Interplay between Oncogenes and Tumor Suppressor Genes in Human Disease

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Unknown venue

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/B978-0-12-394447-4.30056-6
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• The Biology of Cancer

  2015cited by this paper
• Regulation of cancer metabolism by oncogenes and tumor suppressors.

  2014cited by this paper
• Germline PIK3CA and AKT1 mutations in Cowden and Cowden-like syndromes.

  2013cited by this paper
• Cancer Genome Landscapes

  2013cited by this paper
• MYC on the path to cancer.

  2012cited by this paper
• Regulation of cancer cell metabolism

  2011cited by this paper
• A mosaic activating mutation in AKT1 associated with the Proteus syndrome.

  2011cited by this paper
• Mutations in the p53 Tumor Suppressor Gene: Important Milestones at the Various Steps of Tumorigenesis.

  2011cited by this paper
• Noonan syndrome and clinically related disorders.

  2011cited by this paper
• Fyn-dependent regulation of energy expenditure and body weight is mediated by tyrosine phosphorylation of LKB1.

  2010cited by this paper
• Genetic determinants at the interface of cancer and neurodegenerative disease

  2010cited by this paper
• A novel parkin-mediated transcriptional function links p53 to familial Parkinson’s disease

  2010cited by this paper
• Human papillomavirus oncoproteins: pathways to transformation

  2010cited by this paper
• Myc proteins as therapeutic targets

  2010cited by this paper
• The Control of the Metabolic Switch in Cancers by Oncogenes and Tumor Suppressor Genes

  2010cited by this paper
• PTEN and the PI3-kinase pathway in cancer.

  2009cited by this paper
• Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

  2009cited by this paper
• PTEN promoter methylation and LOH of 10q22-23 locus in PTEN expression of ovarian clear cell adenocarcinomas.

  2009cited by this paper
• Blinded by the Light: The Growing Complexity of p53.

  2009cited by this paper
• Cell cycle re-entry mediated neurodegeneration and its treatment role in the pathogenesis of Alzheimer's disease.

  2009cited by this paper
• Hypoxia, HIF1 and glucose metabolism in the solid tumour

  2008cited by this paper
• DJ-1 Decreases Bax Expression through Repressing p53 Transcriptional Activity*

  2008cited by this paper
• PTEN: a new guardian of the genome

  2008cited by this paper
• The Bcl-2 apoptotic switch in cancer development and therapy

  2007cited by this paper
• GEFs and GAPs: critical elements in the control of small G proteins.

  2007cited by this paper
• MAP kinase signalling pathways in cancer

  2007cited by this paper
• AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy

  2007cited by this paper
• Integrative metabolic regulation of peripheral tissue fatty acid oxidation by the SRC kinase family member Fyn.

  2007cited by this paper
• AKT/PKB signaling: navigating downstream.

  2007cited by this paper
• Germline gain-of-function mutations in SOS1 cause Noonan syndrome

  2007cited by this paper
• Neuronal cell cycle re-entry mediates Alzheimer disease-type changes.

  2007cited by this paper
• Receptor tyrosine kinases: mechanisms of activation and signaling.

  2007cited by this paper
• Caspase-3-derived C-terminal Product of Synphilin-1 Displays Antiapoptotic Function via Modulation of the p53-dependent Cell Death Pathway*

  2006cited by this paper
• The Myc oncoprotein as a therapeutic target for human cancer.

  2006cited by this paper
• A role for Brca1 in chromosome end maintenance.

  2006cited by this paper
• Pten (phosphatase and tensin homologue gene) haploinsufficiency promotes insulin hypersensitivity

  2006cited by this paper
• Cancer's molecular sweet tooth and the Warburg effect.

  2006cited by this paper
• Genetic epidemiology of diabetes.

  2005cited by this paper
• The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism

  2005cited by this paper
• Intracellular Aβ42 activates p53 promoter: a pathway to neurodegeneration in Alzheimer's disease

  2005cited by this paper
• Diverse Biochemical Properties of Shp2 Mutants

  2005cited by this paper
• AMP-activated protein kinase is not down-regulated in human skeletal muscle of obese females.

  2004cited by this paper
• AMPK activity and isoform protein expression are similar in muscle of obese subjects with and without type 2 diabetes.

  2004cited by this paper
• The road to Src

  2004cited by this paper
• PI3K-Akt pathway: Its functions and alterations in human cancer

  2004cited by this paper
• The LKB1 tumor suppressor negatively regulates mTOR signaling.

  2004cited by this paper
• A Family with Severe Insulin Resistance and Diabetes Due to a Mutation in AKT2

  2004cited by this paper
• Oncogenic mutations of PIK3CA in human cancers.

  2004cited by this paper
• AMPK as a metabolic switch in rat muscle, liver and adipose tissue after exercise.

  2003cited by this paper
• Control of apoptosis by p53

  2003cited by this paper
• Apoptosis - the p53 network

  2003cited by this paper
• Molecular mechanisms of selective dopaminergic neuronal death in Parkinson's disease.

  2003cited by this paper
• The phosphoinositide 3-kinase pathway.

  2002cited by this paper
• Mutations of the BRAF gene in human cancer

  2002cited by this paper
• NF1 tumor suppressor gene function: narrowing the GAP.

  2001cited by this paper
• Oncogenic kinase signalling

  2001cited by this paper
• Wild-type but Not Parkinson's Disease-related Ala-53 → Thr Mutant α-Synuclein Protects Neuronal Cells from Apoptotic Stimuli*

  2000cited by this paper
• Selective activation of NF-κB subunits in human breast cancer: potential roles for NF-κB2/p52 and for Bcl-3

  2000cited by this paper
• The multiple roles of PTEN in tumor suppression.

  2000cited by this paper
• Oncogenic alterations of metabolism.

  1999cited by this paper
• Alzheimer's disease: The tangled tale of tau

  1999cited by this paper
• Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene.

  1999cited by this paper
• The 5′‐AMP‐activated protein kinase inhibits the transcriptional stimulation by glucose in liver cells, acting through the glucose response complex

  1998cited by this paper
• Type 1 neurofibromatosis: a descriptive analysis of the disorder in 1,728 patients.

  1997cited by this paper
• Correlates of p53- and Fas (CD95)-mediated apoptosis in Alzheimer's disease.

  1997cited by this paper
• Changes of p53 in the brains of patients with Alzheimer's disease.

  1997cited by this paper
• Structure and function of the p53 tumor suppressor gene: clues for rational cancer therapeutic strategies.

  1996cited by this paper
• Tumor suppressor genes.

  1994cited by this paper
• Retinoblastoma protein and the cell cycle.

  1993cited by this paper
• Tumor suppressor genes.

  1991cited by this paper
• A genetic model for colorectal tumorigenesis.

  1990cited by this paper
• ras oncogenes in human cancer: a review.

  1989cited by this paper
• ras GTPase activating protein: signal transmitter and signal terminator.

  1989cited by this paper
• Regulation of carnitine palmitoyltransferase by insulin results in decreased activity and decreased apparent Ki values for malonyl-CoA.

  1987cited by this paper
• Amyloid plaque core protein in Alzheimer disease and Down syndrome.

  1985cited by this paper
• Cellular oncogenes and retroviruses.

  1983cited by this paper
• Isolation of a transforming sequence from a human bladder carcinoma cell line.

  1982cited by this paper
• Human-tumor-derived cell lines contain common and different transforming genes.

  1981cited by this paper
• Transforming activity of human tumor DNAs.

  1981cited by this paper
• DNA related to the transforming gene(s) of avian sarcoma viruses is present in normal avian DNA

  1976cited by this paper
• Suppression of malignancy in human cells

  1976cited by this paper
• Suppression of Malignancy by Cell Fusion

  1969cited by this paper

• The Multi-Target lncRNA–miRNA–mRNA TRIAD in Pancreatic Cancer Diagnosis and Therapy

  2026cites this paper
• Main molecular mechanisms for noncommunicable diseases

  2022cites this paper
• The Efficiency of Play Therapy Based on Cognitive–Behavioral Approach on Aggression of Preschool Children with Attention Deficit/Hyperactivity Disorder

  2016cites this paper