Activators of G-protein signaling 3: a drug addiction molecular gateway

No abstract is available for this paper.

• Publication year

  2010

• Venue

  Behavioural Pharmacology

• Publication date

  2010-09-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1097/FBP.0b013e32833dcfa5PMID 20700046PMCID PMC2963093
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Regulator of G protein–signaling proteins and addictive drugs

  2010cited by this paper
• Brain region specific actions of regulator of G protein signaling 4 oppose morphine reward and dependence but promote analgesia.

  2010cited by this paper
• Reduced nucleus accumbens SK channel activity enhances alcohol seeking during abstinence.

  2010cited by this paper
• Addiction: A Disorder of Choice

  2010cited by this paper
• Identification of a Deubiquitinating Enzyme as a Novel AGS3-Interacting Protein

  2010cited by this paper
• Dopamine receptors in the learning, memory and drug reward circuitry.

  2009cited by this paper
• [Therapeutic approaches to cocaine addiction].

  2009cited by this paper
• Dopamine, Behavioral Economics, and Effort

  2009cited by this paper
• Purinergic signalling in the nervous system: an overview.

  2009cited by this paper
• GoLoco motif proteins binding to Gαi1: insights from molecular simulations

  2009cited by this paper
• Up-Regulation of AGS3 during Morphine Withdrawal Promotes cAMP Superactivation via Adenylyl Cyclase 5 and 7 in Rat Nucleus Accumbens/Striatal Neurons

  2009cited by this paper
• Neurogenetics of Dopaminergic Receptor Supersensitivity in Activation of Brain Reward Circuitry and Relapse: Proposing “Deprivation-Amplification Relapse Therapy” (DART)

  2009cited by this paper
• Metabotropic glutamate receptor ligands as potential therapeutics for addiction.

  2009cited by this paper
• Metabotropic glutamate receptor ligands as potential therapeutics for addiction.

  2009cited by this paper
• Effects of repeated exposure to cocaine on group II metabotropic glutamate receptor function in the rat medial prefrontal cortex: behavioral and neurochemical studies

  2009cited by this paper
• Conditioned cues and the expression of stimulant sensitization in animals and humans.

  2009cited by this paper
• Role of GluR1 expression in nucleus accumbens neurons in cocaine sensitization and cocaine‐seeking behavior

  2008cited by this paper
• Do pharmacological approaches that prevent opioid tolerance target different elements in the same regulatory machinery?

  2008cited by this paper
• Cocaine but not natural reward self-administration nor passive cocaine infusion produces persistent LTP in the VTA.

  2008cited by this paper
• A role of RGS proteins in drug addiction.

  2008cited by this paper
• Concurrent access to sucrose pellets decreases methamphetamine-seeking behavior in Lewis rats.

  2008cited by this paper
• A point mutation to Galphai selectively blocks GoLoco motif binding: direct evidence for Galpha.GoLoco complexes in mitotic spindle dynamics.

  2008cited by this paper
• Addictive drugs modulate GIRK-channel signaling by regulating RGS proteins.

  2008cited by this paper
• Selective alterations of brain dopamine D2 receptor binding in cirrhotic patients: results of a 11C-N-methylspiperone PET study

  2008cited by this paper
• The incentive sensitization theory of addiction: some current issues

  2008cited by this paper
• Excitotoxic lesions of the basolateral amygdala impair the acquisition of cocaine-seeking behaviour under a second-order schedule of reinforcement

  2008cited by this paper
• An update on adenosine A2A-dopamine D2 receptor interactions: implications for the function of G protein-coupled receptors.

  2008cited by this paper
• Gene expression profiling of the rewarding effect caused by methamphetamine in the mesolimbic dopamine system.

  2008cited by this paper
• Nucleus accumbens AGS3 expression drives ethanol seeking through Gβγ

  2008influential reference
• Drug Addiction as a Pathology of Staged Neuroplasticity

  2008cited by this paper
• REVIEW

  2008cited by this paper
• Glutamate Release in the Nucleus Accumbens Core Is Necessary for Heroin Seeking

  2008cited by this paper
• Varenicline, an α4β2 nicotinic acetylcholine receptor partial agonist, selectively decreases ethanol consumption and seeking

  2007cited by this paper
• Psychostimulants, madness, memory ... and RGS proteins?

  2007cited by this paper
• Inhibition by cocaine of G protein-activated inwardly rectifying K+ channels expressed in Xenopus oocytes.

  2007cited by this paper
• Varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist, selectively decreases ethanol consumption and seeking.

  2007cited by this paper
• Aripiprazole blocks reinstatement of cocaine seeking in an animal model of relapse.

  2007cited by this paper
• Insights into the Role of Dopamine Receptor Systems in Learning and Memory

  2007cited by this paper
• Addiction-Related Alterations in D1 and D2 Dopamine Receptor Behavioral Responses Following Chronic Cocaine Self-Administration

  2007cited by this paper
• Neural mechanisms of addiction: the role of reward-related learning and memory.

  2006cited by this paper
• Toward a model of drug relapse: an assessment of the validity of the reinstatement procedure

  2006cited by this paper
• Clinical potential of GABAB receptor modulators.

  2006cited by this paper
• REVIEW: Behavioural assessment of drug reinforcement and addictive features in rodents: an overview

  2006cited by this paper
• Environmental cues, alcohol seeking, and consumption in baboons: effects of response requirement and duration of alcohol abstinence.

  2006cited by this paper
• Animal models and brain circuits in drug addiction.

  2006cited by this paper
• Alcoholism and neuropeptides: an update.

  2006cited by this paper
• Dopamine D3 as well as D2 receptor ligands attenuate the cue-induced cocaine-seeking in a relapse model in rats.

  2006cited by this paper
• The neural basis of addiction: a pathology of motivation and choice.

  2005cited by this paper
• G alpha selectivity and inhibitor function of the multiple GoLoco motif protein GPSM2/LGN.

  2005cited by this paper
• The corticotropin-releasing factor (CRF) family of neuropeptides in inflammation: potential therapeutic applications.

  2005cited by this paper
• Long‐Term Gene Expression in the Nucleus Accumbens Following Heroin Administration is Subregion‐Specific and Depends on the Nature of Drug Administration

  2005cited by this paper
• Differential regulation of ionotropic glutamate receptor subunits following cocaine self-administration.

  2005cited by this paper
• The "Ups and Downs" of Signaling Cascades in Addiction

  2005cited by this paper
• Correlation of alcohol craving with striatal dopamine synthesis capacity and D2/3 receptor availability: a combined [18F]DOPA and [18F]DMFP PET study in detoxified alcoholic patients.

  2005cited by this paper
• D2 dopamine receptor activation of potassium channels is selectively decoupled by Gαi‐specific GoLoco motif peptides

  2005cited by this paper
• Is there a common molecular pathway for addiction?

  2005cited by this paper
• Neuronal substrates of relapse to cocaine-seeking behavior: role of prefrontal cortex.

  2005cited by this paper
• Stimulant-induced adaptations in neostriatal matrix and striosome systems: transiting from instrumental responding to habitual behavior in drug addiction.

  2005cited by this paper
• Activator of G protein signaling 3 regulates opiate activation of protein kinase A signaling and relapse of heroin-seeking behavior.

  2005influential reference
• Synaptic plasticity and drug addiction.

  2005cited by this paper
• Regulators of G protein signaling & drugs of abuse.

  2005cited by this paper
• Gα selectivity and inhibitor function of the multiple GoLoco motif protein GPSM2/LGN

  2005cited by this paper
• The GAPs, GEFs, and GDIs of heterotrimeric G-protein alpha subunits

  2005cited by this paper
• Alcohol dependence is associated with blunted dopamine transmission in the ventral striatum.

  2005cited by this paper
• Modification by Dopaminergic Drugs of Choice Behavior under Concurrent Schedules of Intravenous Saline and Food Delivery in Monkeys

  2004cited by this paper
• Limbic and Motor Circuitry Underlying Footshock-Induced Reinstatement of Cocaine-Seeking Behavior

  2004cited by this paper
• Guanine nucleotide dissociation inhibitor activity of the triple GoLoco motif protein G18: alanine-to-aspartate mutation restores function to an inactive second GoLoco motif.

  2004cited by this paper
• Memory and Addiction: Shared Neural Circuitry and Molecular Mechanisms

  2004cited by this paper
• Identification and characterization of AGS4: a protein containing three G-protein regulatory motifs that regulate the activation state of Gialpha.

  2004cited by this paper
• Memory and addiction: shared neural circuitry and molecular mechanisms.

  2004cited by this paper
• Gene transcripts selectively down‐regulated in the shell of the nucleus accumbens long after heroin self‐administration are up‐regulated in the core independent of response contingency

  2004cited by this paper
• Opioid receptors.

  2004cited by this paper
• Reinstatement of cocaine-reinforced responding in the rat

  2004cited by this paper
• Identification and Characterization of AGS4

  2004cited by this paper
• Activator of G protein signaling 3: a gatekeeper of cocaine sensitization and drug seeking.

  2004influential reference
• The ups and downs of addiction: role of metabotropic glutamate receptors.

  2004cited by this paper
• Intra-accumbens pertussis toxin sensitizes rats to the locomotor activating effects of a single cocaine challenge.

  2003cited by this paper
• Regulation of RGS proteins by chronic morphine in rat locus coeruleus

  2003cited by this paper
• Drug Addiction, Relapse, and the Amygdala

  2003cited by this paper
• Neuroadaptive effects of active versus passive drug administration in addiction research.

  2003cited by this paper
• Prefrontal Glutamate Release into the Core of the Nucleus Accumbens Mediates Cocaine-Induced Reinstatement of Drug-Seeking Behavior

  2003cited by this paper
• Dopamine: a potential substrate for synaptic plasticity and memory mechanisms.

  2003cited by this paper
• Decreased striatal dopamine D1 receptor-stimulated adenylyl cyclase activity in human methamphetamine users.

  2003cited by this paper
• Comparative Inter-strain Sequence Analysis of the Putative Regulatory Region of Murine Psychostimulant-regulated Gene GNB1 (G Protein β1 Subunit Gene)

  2003cited by this paper
• The reinstatement model of drug relapse: history, methodology and major findings

  2003cited by this paper
• Adaptations in adenosine signaling in drug dependence: therapeutic implications.

  2003cited by this paper
• Thermodynamic Characterization of the Binding of Activator of G Protein Signaling 3 (AGS3) and Peptides Derived from AGS3 with Gαi1*

  2003influential reference
• Cocaine sensitization: modulation by dopamine D2 receptors.

  2002cited by this paper
• Regulators of G protein signaling (RGS proteins): novel central nervous system drug targets.

  2002cited by this paper
• Structural determinants for GoLoco-induced inhibition of nucleotide release by Gα subunits

  2002cited by this paper
• Modulation of Group II Metabotropic Glutamate Receptor Signaling by Chronic Cocaine

  2002cited by this paper
• A GPR-protein interaction surface of Gi(alpha): implications for the mechanism of GDP-release inhibition.

  2002cited by this paper
• A Single Dose of Methamphetamine Rescues the Blunted Dopamine D1‐Receptor Activity in the Neocortex of D2‐ and D3‐Receptor Knockout Mice

  2002cited by this paper
• Tolerance and sensitization to the locomotor-activating effects of cocaine are mediated via independent mechanisms.

  2002cited by this paper
• Molecular mechanisms for heterologous sensitization of adenylate cyclase.

  2002cited by this paper
• Cocaine Administered into the Medial Prefrontal Cortex Reinstates Cocaine-Seeking Behavior by Increasing AMPA Receptor-Mediated Glutamate Transmission in the Nucleus Accumbens

  2002cited by this paper
• OPIOID RECEPTORS

  2002cited by this paper
• Cellular Regulation of RGS Proteins: Modulators and Integrators of G Protein Signaling

  2002cited by this paper
• Neurobiology of relapse to alcohol in rats.

  2002cited by this paper
• Social dominance in monkeys: dopamine D2 receptors and cocaine self-administration

  2002cited by this paper

• Properties of biomolecular condensates defined by the receptor independent activator of G protein Signaling 3 (AGS3).

  2024cites this paper
• Proteomic analysis of anti-aging effects of Dendrobium nobile Lindl. alkaloids in aging-accelerated SAMP8 mice.

  2023cites this paper
• Biomolecular Condensates defined by Receptor Independent Activator of G protein Signaling: Properties and Regulation

  2023cites this paper
• Regulation of G Protein βγ Signaling.

  2018cites this paper
• Two novel candidate genes identified in adults from the Newfoundland population with addictive tendencies towards food.

  2017influential citation
• Regulation of Airway Inflammation by G-protein Regulatory Motif Peptides of AGS3 protein

  2016cites this paper
• Development of inhibitors of heterotrimeric Gαi subunits.

  2014cites this paper
• Fine-tuning of GPCR signals by intracellular G protein modulators.

  2013cites this paper
• Family-Based Genetic Association Analysis: Methods and Applications to Addiction Phenotypes

  2012cites this paper
• Group II activators of G‐protein signalling and proteins containing a G‐protein regulatory motif

  2012cites this paper
• Neuronal Functions of Activators of G Protein Signaling

  2012cites this paper
• Striatal Signal Transduction and Drug Addiction

  2011cites this paper