Probiotics normalize the gut-brain-microbiota axis in immunodeficient mice.

No abstract is available for this paper.

• Publication year

  2014

• Venue

  American Journal of Physiology - Gastrointestinal and Liver Physiology

• Publication date

  2014-10-15

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1152/ajpgi.00238.2014PMID 25190473PMCID PMC4200314
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Association between Faecalibacterium prausnitzii Reduction and Inflammatory Bowel Disease: A Meta-Analysis and Systematic Review of the Literature

  2014cited by this paper
• The microbiota–gut–brain axis in gastrointestinal disorders: stressed bugs, stressed brain or both?

  2014cited by this paper
• Effects of Lactobacillus helveticus on murine behavior are dependent on diet and genotype and correlate with alterations in the gut microbiome.

  2013cited by this paper
• Host interactions with Segmented Filamentous Bacteria: an unusual trade-off that drives the post-natal maturation of the gut immune system.

  2013cited by this paper
• Brain-gut interactions in inflammatory bowel disease.

  2013cited by this paper
• The contributing role of the intestinal microbiota in stressor-induced increases in susceptibility to enteric infection and systemic immunomodulation.

  2012cited by this paper
• STRESS AND THE GUT: PATHOPHYSIOLOGY, CLINICAL CONSEQUENCES, DIAGNOSTIC APPROACH AND TREATMENT OPTIONS

  2012cited by this paper
• Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour

  2012cited by this paper
• The intestinal microbiota affect central levels of brain-derived neurotropic factor and behavior in mice.

  2011cited by this paper
• Stress and the gut: pathophysiology, clinical consequences, diagnostic approach and treatment options.

  2011cited by this paper
• Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve

  2011cited by this paper
• Regulation of innate and adaptive immunity by the commensal microbiota.

  2011influential reference
• The anxiolytic effect of Bifidobacterium longum NCC3001 involves vagal pathways for gut–brain communication

  2011cited by this paper
• Recommendations for probiotic use-2011 update.

  2011cited by this paper
• Protective autoimmunity functions by intracranial immunosurveillance to support the mind: The missing link between health and disease

  2010cited by this paper
• Probiotics prevent death caused by Citrobacter rodentium infection in neonatal mice.

  2010cited by this paper
• Bacterial infection causes stress-induced memory dysfunction in mice

  2010cited by this paper
• Immune adaptations that maintain homeostasis with the intestinal microbiota

  2010cited by this paper
• Probiotics and the gut microbiota in intestinal health and disease

  2010cited by this paper
• Maternal deprivation alters epithelial secretory cell lineages in rat duodenum: role of CRF-related peptides

  2010cited by this paper
• Host-bacterial symbiosis in health and disease.

  2010cited by this paper
• Unraveling mechanisms of action of probiotics.

  2009cited by this paper
• Acute stress increases colonic paracellular permeability in mice through a mast cell-independent mechanism: involvement of pancreatic trypsin.

  2009cited by this paper
• A strain of Lactobacillus plantarum affects segmented filamentous bacteria in the intestine of immunosuppressed mice.

  2008cited by this paper
• Adaptive immunity affects learning behavior in mice.

  2008cited by this paper
• Role of the Brain-Gut Axis in the Pathophysiology of Crohn’s Disease

  2008cited by this paper
• Pathophysiological mechanisms of stress-induced intestinal damage.

  2008cited by this paper
• Behavioral and serotonergic consequences of decreasing or increasing hippocampus brain-derived neurotrophic factor protein levels in mice.

  2008cited by this paper
• Immunity and cognition: what do age-related dementia, HIV-dementia and 'chemo-brain' have in common?

  2008cited by this paper
• Corticotropin-releasing factor receptor-1: a therapeutic target for cardiac autonomic disturbances

  2007cited by this paper
• Probiotic treatment of rat pups normalises corticosterone release and ameliorates colonic dysfunction induced by maternal separation

  2007cited by this paper
• Synergy between Lactobacillus paracasei and its bacterial products to counteract stress-induced gut permeability and sensitivity increase in rats.

  2007cited by this paper
• Immune cells contribute to the maintenance of neurogenesis and spatial learning abilities in adulthood

  2006cited by this paper
• Neonatal Maternal Separation Causes Colonic Dysfunction in Rat Pups Including Impaired Host Resistance

  2006cited by this paper
• Cellular and molecular mechanisms of hippocampal activation by acute stress are age-dependent

  2006cited by this paper
• Abnormal microbiota composition in the ileocolonic mucosa of Crohn's disease patients as revealed by polymerase chain reaction‐denaturing gradient gel electrophoresis

  2006cited by this paper
• Probiotics prevent bacterial translocation and improve intestinal barrier function in rats following chronic psychological stress

  2006cited by this paper
• Recommendations for probiotic use.

  2006cited by this paper
• Hippocampal c-fos is necessary for long-term memory of a socially transmitted food preference.

  2005cited by this paper
• Stress hormones and human memory function across the lifespan.

  2005cited by this paper
• Stress Impairs Murine Intestinal Barrier Function: Improvement by Glucagon-Like Peptide-2

  2005cited by this paper
• Amelioration of the effects of Citrobacter rodentium infection in mice by pretreatment with probiotics.

  2005cited by this paper
• Aberrant expansion of segmented filamentous bacteria in IgA-deficient gut

  2004cited by this paper
• T cell deficiency leads to cognitive dysfunction: implications for therapeutic vaccination for schizophrenia and other psychiatric conditions.

  2004cited by this paper
• Signaling Pathways in Brain Involved in Predisposition and Pathogenesis of Stress‐Related Disease: Genetic and Kinetic Factors Affecting the MR/GR Balance

  2004cited by this paper
• In vitro fermentability of dextran, oligodextran and maltodextrin by human gut bacteria

  2000cited by this paper
• Corticosterone effects on BDNF mRNA expression in the rat hippocampus during morris water maze training.

  1999cited by this paper
• A new one-trial test for neurobiological studies of memory in rats. III. Spatial vs. non-spatial working memory.

  1992cited by this paper
• RAG-1-deficient mice have no mature B and T lymphocytes.

  1992cited by this paper
• A new one-trial test for neurobiological studies of memory in rats. 1: Behavioral data.

  1988cited by this paper

• Therapeutic Application of Postbiotics in the Management of Polycystic Ovarian Syndrome

  2026cites this paper
• The Microbiome–Neurodegeneration Interface: Mechanisms, Evidence, and Future Directions

  2026cites this paper
• Impact of Gut–Brain Axis and Probiotics on Alzheimer’s Disease

  2025cites this paper
• Circulating extracellular vesicle microRNAs mediate immune modulation of social behavior in mice

  2025cites this paper
• mTORC1-Independent IgA Production: A Unique Pathway for Gut Immune Homeostasis.

  2025cites this paper
• Interplay between antipredator behavior, parasitism, and gut microbiome in wild stickleback populations

  2025cites this paper
• Exploring neurotransmitter regulation following probiotic supplementation in adults with subthreshold depression: A secondary analysis of a randomized controlled trial.

  2025cites this paper
• Add-on probiotics for inflammatory depression - A double-blind randomized placebo-controlled trial.

  2025cites this paper
• Exploring the microbiota-gut-brain axis: impact on brain structure and function

  2025cites this paper
• Synbiotic diet produces antidepressant-like effects but alters ketamine activity in an avian model of treatment-resistant depression.

  2025cites this paper
• How the gut microbiome shapes learning and memory: A comprehensive review

  2025cites this paper
• Clinically approved immunomodulators ameliorate behavioral changes in a mouse model of hereditary spastic paraplegia type 11

  2024cites this paper
• The emerging roles of neuroactive components produced by gut microbiota

  2024cites this paper
• The efficacy of Lactobacillus and Bifidobacterium in patients with schizophrenia: a meta-analysis

  2024cites this paper
• The gut microbiome in patients with Cushing’s disease affects depression- and anxiety-like behavior in mice

  2024cites this paper
• Health benefits and risks of fermented foods—the PIMENTO initiative

  2024cites this paper
• Unlocking the mind-gut connection: Impact of human microbiome on cognition.

  2024cites this paper
• A novel probiotic formula, BLLL, ameliorates chronic stress-induced depression-like behaviors in mice by reducing neuroinflammation and increasing neurotrophic factors

  2024cites this paper
• Exploring the complex interplay: gut microbiome, stress, and leptospirosis

  2024cites this paper
• BDNF/CREB signaling pathway contribution in depression pathogenesis: A survey on the non-pharmacological therapeutic opportunities for gut microbiota dysbiosis.

  2024cites this paper
• Understanding the Gut–Brain Axis and Its Therapeutic Implications for Neurodegenerative Disorders

  2023cites this paper
• Probiotics Show Promise as a Novel Natural Treatment for Neurological Disorders.

  2023cites this paper
• Rol de la suplementación con probióticos en el desarrollo y la evolución de la enfermedad de Alzheimer y la enfermedad de Parkinson: una revisión narrativa

  2023cites this paper
• The Role of Chronic Fatigue in Patients with Crohn’s Disease

  2023cites this paper
• The microbiota-gut-brain axis in hippocampus-dependent learning and memory: current state and future challenges.

  2023cites this paper
• Combined Supplementation of Clostridium butyricum and Bifidobacterium infantis Diminishes Chronic Unpredictable Mild Stress-Induced Intestinal Alterations via Activation of Nrf-2 Signaling Pathway in Rats

  2023cites this paper
• The Muscle‐Gut‐Brain Axis and Psychiatric Illness

  2023cites this paper
• The gut microbiota contributes to the pathogenesis of anorexia nervosa in humans and mice

  2023cites this paper
• History of childhood physical abuse is associated with gut microbiota diversity among adult psychiatric inpatients.

  2023cites this paper
• Brain and gut microbiota disorders in the psychopathology of anorexia nervosa

  2022cites this paper
• Updates on the Role of Probiotics against Different Health Issues: Focus on Lactobacillus

  2022cites this paper
• Probiotic Mechanism to Modulate the Gut-Brain Axis (GBA)

  2022cites this paper
• A Reciprocal Link Between Gut Microbiota, Inflammation and Depression

  2022cites this paper
• The microbiota-gut-brain axis in pathogenesis of depression: A narrative review.

  2022cites this paper
• The Role of the Gut Microbiome in Psychiatric Disorders

  2022cites this paper
• Effect of the Mediterranean diet and probiotic supplementation in the management of mild cognitive impairment: Rationale, methods, and baseline characteristics

  2022cites this paper
• Functional Gastrointestinal Disorders with Psychiatric Symptoms: Involvement of the Microbiome–Gut–Brain Axis in the Pathophysiology and Case Management

  2022cites this paper
• Different oral and gut microbial profiles in those with Alzheimer's disease consuming anti-inflammatory diets

  2022cites this paper
• Investigation of memory-enhancing effects of Streptococcus thermophilus EG007 in mice and elucidating molecular and metagenomic characteristics using nanopore sequencing

  2022cites this paper
• Impact of Environmental Pollutants on Gut Microbiome and Mental Health via the Gut–Brain Axis

  2022cites this paper
• The Many Ages of Microbiome–Gut–Brain Axis

  2022cites this paper
• Obesity and the Brain

  2022cites this paper
• Intermittent fasting mitigates cognitive deficits in Alzheimer’s disease via the gut-brain axis

  2022cites this paper
• A Reciprocal Link Between Gut Microbiota, Inflammation and Depression: A Place for Probiotics?

  2022cites this paper
• Psychoactive Effects of Lactobacillus johnsonii BS15 on Preventing Memory Dysfunction Induced by Acute Ethanol Exposure Through Modulating Intestinal Microenvironment and Improving Alcohol Metabolic Level

  2022cites this paper
• An anxious relationship between Autism Spectrum Disorder and Gut Microbiota: A tangled chemistry?

  2022cites this paper
• Drosophila Model for Studying Gut Microbiota in Behaviors and Neurodegenerative Diseases

  2022cites this paper
• The regulative effect and repercussion of probiotics and prebiotics on osteoporosis: involvement of brain-gut-bone axis

  2022cites this paper
• Ingestion of Bifidobacterium longum changes miRNA levels in the brains of mice

  2021cites this paper
• The Microbiome-Gut-Brain Axis and Resilience to Developing Anxiety or Depression under Stress

  2021cites this paper
• Inflammatory Depression—Mechanisms and Non-Pharmacological Interventions

  2021cites this paper
• The microbiota–gut–brain axis: A novel nutritional therapeutic target for growth retardation

  2021cites this paper
• Diet, Microbiota and the Gut-Brain Axis

  2021cites this paper
• Skin-brain axis signaling mediates behavioral changes after skin wounding

  2021cites this paper
• Hidden Role of Gut Microbiome Dysbiosis in Schizophrenia: Antipsychotics or Psychobiotics as Therapeutics?

  2021cites this paper
• Accumulation of cytotoxic T cells in the aged CNS leads to axon degeneration and contributes to cognitive and motor decline

  2021cites this paper
• The Gut Microbiome in Schizophrenia and the Potential Benefits of Prebiotic and Probiotic Treatment

  2021cites this paper
• Obesity Impairs Short-Term and Working Memory through Gut Microbial Metabolism of Aromatic Amino Acids.

  2020cites this paper
• Depression's Unholy Trinity: Dysregulated Stress, Immunity, and the Microbiome.

  2020cites this paper
• The Effect of Probiotic Intervention in Ameliorating the Altered Central Nervous System Functions in Neurological Disorders: A Review

  2020cites this paper
• Loss of T cells influences sex differences in stress-related gene expression.

  2020cites this paper
• The Role of the Gut Microbiota in Dietary Interventions for Depression and Anxiety

  2020cites this paper
• Dysregulation of synaptic pruning as a possible link between intestinal microbiota dysbiosis and neuropsychiatric disorders

  2020cites this paper
• Genetic and metabolic links between the murine microbiome and memory

  2020cites this paper
• Is there a role of gut microbiota in mental health?

  2020cites this paper
• High-altitude Tibetan fermented milk ameliorated cognitive dysfunction by modified gut microbiota in Alzheimer's disease transgenic mice.

  2020cites this paper
• Primary Care Revisited: Interdisciplinary Perspectives for a New Era

  2020cites this paper
• Tryptophan Metabolites Along the Microbiota-Gut-Brain Axis: An Interkingdom Communication System Influencing the Gut in Health and Disease

  2020cites this paper
• A murine model of pediatric inflammatory bowel disease causes microbiota-gut-brain axis deficits in adulthood.

  2020cites this paper
• Neonatal Enteropathogenic Escherichia coli Infection Disrupts Microbiota-Gut-Brain Axis Signaling

  2020cites this paper
• The effects of psychobiotics on the microbiota-gut-brain axis in early-life stress and neuropsychiatric disorders.

  2020cites this paper
• Intermingling of gut microbiota with brain: Exploring the role of probiotics in battle against depressive disorders.

  2020cites this paper
• Is good memory always a good thing? An early offset of infantile amnesia predicts anxiety-like behavior throughout development in rats.

  2020cites this paper
• Public Health in the Context of Environment and Housing

  2020cites this paper
• The microbiota-gut-brain axis: Focus on the fundamental communication pathways.

  2020cites this paper
• ADIPS 2020 guideline for pre‐existing diabetes and pregnancy

  2020cites this paper
• The impact of the microbiota-gut-brain axis on Alzheimer's disease pathophysiology.

  2020cites this paper
• The use of probiotics in depression

  2020cites this paper
• Two gut microbes are necessary and sufficient for normal cognition in Drosophila melanogaster

  2019cites this paper
• The antidepressant-like effect of probiotics and their faecal abundance may be modulated by the cohabiting gut microbiota in rats.

  2019cites this paper
• Nod‐like receptors are critical for gut–brain axis signalling in mice

  2019cites this paper
• Optimal Criteria for the Selection of Probiotics, Based on their Mode of Action

  2019cites this paper
• Topical Application of Adult Cecal Contents to Eggs Transplants Spore-Forming Microbiota but Not Other Members of the Microbiota to Chicks

  2019cites this paper
• The connection between microbiome and schizophrenia.

  2019cites this paper
• Probiotic food consumption is associated with lower severity and prevalence of depression: A nationwide cross-sectional study.

  2019cites this paper
• Method of preparation, visualization and ultrastructural analysis of a formulation of probiotic Bacillus subtilis KATMIRA1933 produced by solid-phase fermentation

  2019cites this paper
• Influence of the microbiota-gut-brain axis on behavior and welfare in farm animals: A review.

  2019cites this paper
• The gut microbiota composition affects dietary polyphenols-mediated cognitive resilience in mice by modulating the bioavailability of phenolic acids

  2019cites this paper
• Mast Cells in Gut and Brain and Their Potential Role as an Emerging Therapeutic Target for Neural Diseases

  2019cites this paper
• The Acute Influence of Acid Suppression with Esomeprazole on Gastrointestinal Microbiota and Brain Gene Expression Profiles in a Murine Model of Restraint Stress.

  2019cites this paper
• Nod-like receptors are critical for gut-brain axis signaling

  2019cites this paper
• Cross‐species examination of single‐ and multi‐strain probiotic treatment effects on neuropsychiatric outcomes

  2019cites this paper
• Lactobacillus Bacteria: Biological and Therapeutic Properties

  2019cites this paper
• The Microbiota-Gut-Brain Axis.

  2019cites this paper
• Intestinal Lactobacillus in health and disease, a driver or just along for the ride?

  2018cites this paper
• The Microbiome: A New Target for Research and Treatment of Schizophrenia and its Resistant Presentations? A Systematic Literature Search and Review

  2018cites this paper
• Targeting the gut microbiota to influence brain development and function in early life.

  2018cites this paper
• Psychobiotics: Next Generation Treatment for Mental Disorders

  2018cites this paper
• Gut microbiota regulates mouse behaviors through glucocorticoid receptor pathway genes in the hippocampus

  2018cites this paper
• Targeting the Microbiota, From Irritable Bowel Syndrome to Mood Disorders: Focus on Probiotics and Prebiotics

  2018cites this paper