Genetic and regulatory architecture of Alzheimer's disease in the APOE region

A. Kulminski,Leonardo Shu,Yury Loika,Liang He,A. Nazarian,K. Arbeev,S. Ukraintseva,A. Yashin,Irina Culminskaya

Published 2020 in Alzheimer's & Dementia

ABSTRACT

Apolipoprotein E (APOE) ε2 and ε4 alleles encoded by rs7412 and rs429358 polymorphisms, respectively, are landmark contra and pro “risk” factors for Alzheimer's disease (AD).

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