Mapping the Murine Cardiac 26S Proteasome Complexes

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Circulation Research

• Publication date

  2006-08-18

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1161/01.RES.0000237386.98506.f7PMID 16857966
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The ubiquitin-proteasome system in cardiac physiology and pathology.

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• Regulation of Murine Cardiac 20S Proteasomes: Role of Associating Partners

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• Oxidized and Ubiquitinated Proteins May Predict Recovery of Postischemic Cardiac Function: Essential Role of the Proteasome

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• Mobilizing the proteolytic machine: cell biological roles of proteasome activators and inhibitors.

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• Intrasarcoplasmic Amyloidosis Impairs Proteolytic Function of Proteasomes in Cardiomyocytes by Compromising Substrate Uptake

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• Impairment of the ubiquitin-proteasome system by truncated cardiac myosin binding protein C mutants.

  2005cited by this paper
• The Murine Cardiac 26S Proteasome: An Organelle Awaiting Exploration

  2005cited by this paper
• Molecular and Functional Signature of Heart Hypertrophy During Pregnancy

  2005cited by this paper
• Protein-protein interactions among human 20S proteasome subunits and proteassemblin.

  2004cited by this paper
• Inhibitors of the eukaryotic 20S proteasome core particle: a structural approach.

  2004cited by this paper
• The proteasome.

  2004cited by this paper
• Phosphorylation of 20S proteasome alpha subunit C8 (alpha7) stabilizes the 26S proteasome and plays a role in the regulation of proteasome complexes by gamma-interferon.

  2004cited by this paper
• N-Terminal modifications of the 19S regulatory particle subunits of the yeast proteasome.

  2003cited by this paper
• Proteasome inhibition ablates activation of NF-kappa B in myocardial reperfusion and reduces reperfusion injury.

  2003cited by this paper
• Mapping and Structural Dissection of Human 20 S Proteasome Using Proteomic Approaches*

  2002cited by this paper
• Mitochondrial PKCepsilon and MAPK form signaling modules in the murine heart: enhanced mitochondrial PKCepsilon-MAPK interactions and differential MAPK activation in PKCepsilon-induced cardioprotection.

  2002cited by this paper
• Gankyrin Is an Ankyrin-repeat Oncoprotein That Interacts with CDK4 Kinase and the S6 ATPase of the 26 S Proteasome*

  2002cited by this paper
• The role of the ubiquitin-proteasome pathway in the formation of mallory bodies.

  2002cited by this paper
• Identification of the 19S regulatory particle subunits from the rice 26S proteasome.

  2002cited by this paper
• The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction.

  2002cited by this paper
• Welcome to the machine: a cardiologist's introduction to protein folding and degradation.

  2002cited by this paper
• The structure of the mammalian 20S proteasome at 2.75 A resolution.

  2002cited by this paper
• A proteasome inhibitor confers cardioprotection.

  2002cited by this paper
• Protein Kinase C ε Signaling Complexes Include Metabolism- and Transcription/Translation-related Proteins

  2002cited by this paper
• The ubiquitin-proteasome 26s pathway in liver cell protein turnover: effect of ethanol and drugs.

  2001cited by this paper
• Up-regulation of the proteasome subunit LMP7 in tissues of endotoxemic rats.

  2000cited by this paper
• Developmentally regulated, alternative splicing of the Rpn10 gene generates multiple forms of 26S proteasomes

  2000cited by this paper
• A proteasome howdunit: the case of the missing signal.

  2000cited by this paper
• Exercise preconditioning against hydrogen peroxide-induced oxidative damage in proteins of rat myocardium.

  2000cited by this paper
• Nalpha -terminal acetylation of eukaryotic proteins.

  2000cited by this paper
• Nα-terminal Acetylation of Eukaryotic Proteins*

  2000cited by this paper
• Association of Increased Ubiquitinated Proteins with Cardiac Apoptosis

  2000cited by this paper
• Subcellular localization of proteasomes and their regulatory complexes in mammalian cells.

  2000cited by this paper
• PKC-dependent activation of p44/p42 MAPKs during myocardial ischemia-reperfusion in conscious rabbits.

  1999cited by this paper
• Cardioprotective effects of a novel proteasome inhibitor following ischemia and reperfusion in the isolated perfused rat heart.

  1999cited by this paper
• The proteasome.

  1999cited by this paper
• Comparative resistance of the 20S and 26S proteasome to oxidative stress.

  1998cited by this paper
• cDNA cloning and characterization of a human proteasomal modulator subunit, p27 (PSMD9).

  1998cited by this paper
• Structure of 20S proteasome from yeast at 2.4Å resolution

  1997cited by this paper
• Electrostatic interaction of myristoylated proteins with membranes: simple physics, complicated biology.

  1997cited by this paper
• Structure and functions of the 20S and 26S proteasomes.

  1996cited by this paper
• Protein Kinase A Phosphorylation of the Proteasome: A Contribution to the α‐Secretase Pathway in Human Cells

  1996cited by this paper
• γ-lnterferon and expression of MHC genes regulate peptide hydrolysis by proteasomes

  1995cited by this paper
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  1995cited by this paper
• Analysis of molecular masses and oligomeric states of protein complexes by blue native electrophoresis and isolation of membrane protein complexes by two-dimensional native electrophoresis.

  1994cited by this paper
• Binding of acylated peptides and fatty acids to phospholipid vesicles: pertinence to myristoylated proteins.

  1993cited by this paper
• Gamma-interferon and expression of MHC genes regulate peptide hydrolysis by proteasomes.

  1993cited by this paper
• Proteasomes (multi-protease complexes) as 20 S ring-shaped particles in a variety of eukaryotic cells.

  1988cited by this paper
• Attachment and maintenance of adult rabbit cardiac myocytes in primary cell culture.

  1988cited by this paper
• The FASEB Journal express article 10.1096/fj.05-3973fje. Published online September 27, 2005.

  year unknowncited by this paper

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  2025cites this paper
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  2024influential citation
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  2024cites this paper
• Proteomic insights from extracellular vesicles into the molecular mechanisms of health effects induced by Per- and polyfluoroalkyl substances.

  2024cites this paper
• Genetic ablation of Lmp2 increases the susceptibility for impaired cardiac function

  2024cites this paper
• CARMIL1 regulates liver cancer cell proliferation by activating the ERK/mTOR pathway through the TRIM27/p53 axis.

  2024cites this paper
• Lipid-anchored Proteasomes Control Membrane Protein Homeostasis

  2023cites this paper
• Western blotting (immunoblotting): history, theory, uses, protocol and problems.

  2023cites this paper
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  2023cites this paper
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  2023cites this paper
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  2023cites this paper
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  2023cites this paper
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  2022cites this paper
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  2022cites this paper
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• Activity of immunoproteasome inhibitor ONX-0914 in acute lymphoblastic leukemia expressing MLL–AF4 fusion protein

  2021cites this paper
• Structure, Dynamics and Function of the 26S Proteasome.

  2021cites this paper
• Exploring the proteasome system: A novel concept of proteasome inhibition and regulation.

  2020cites this paper
• Phosphorylation Modifications Regulating Cardiac Protein Quality Control Mechanisms

  2020cites this paper
• Dynamic Regulation of the 26S Proteasome: From Synthesis to Degradation

  2019cites this paper
• Altered proteasome function in right ventricular hypertrophy.

  2019cites this paper
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  2019cites this paper
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  2019cites this paper
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  2018cites this paper
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  2018cites this paper
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  2017cites this paper
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  2016cites this paper
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  2016cites this paper
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  2016cites this paper
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  2016cites this paper
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  2016cites this paper
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  2016cites this paper
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  2014cites this paper
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• A novel spectral library workflow to enhance protein identifications.

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  2013cites this paper
• Pulmonary Inflammation Loss of ABCG1 Results in Chronic

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  2013cites this paper
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  2013cites this paper
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  2013cites this paper
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  2012cites this paper
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  2012cites this paper
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  2012cites this paper
• N-myristoylation of the Rpt2 subunit regulates intracellular localization of the yeast 26S proteasome.

  2012cites this paper
• Physiological and pathological role of the ubiquitin-proteasome system in the vascular smooth muscle cell.

  2012cites this paper
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  2012cites this paper
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  2011cites this paper
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• Cardiac atrophy due to cancer: Characterization, Mechanisms and Sex Differences

  2011cites this paper
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  2011cites this paper
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