ATP-Binding Cassette Transporters Are Targets for the Development of Antibacterial Vaccines and Therapies

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Infection and Immunity

• Publication date

  2004-12-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/IAI.72.12.6757-6763.2004PMID 15557595PMCID PMC529116
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Cloning and characterization of a Campylobacter jejuni 72Dz/92 gene encoding a 30 kDa immunopositive protein, component of the ABC transport system; expression of the gene in avirulent Salmonella typhimurium.

  2006cited by this paper
• Crystallography of membrane proteins, major targets in drug design.

  2003cited by this paper
• The sloABCR Operon of Streptococcus mutans Encodes an Mn and Fe Transport System Required for Endocarditis Virulence and Its Mn-Dependent Repressor

  2003cited by this paper
• SufC: an unorthodox cytoplasmic ABC/ATPase required for [Fe—S] biogenesis under oxidative stress

  2003cited by this paper
• Novel protein vaccine candidates against Group B streptococcal infection identified using alkaline phosphatase fusions.

  2003cited by this paper
• A solute binding protein of Streptococcus pneumoniae iron transport.

  2003cited by this paper
• Structure-activity relationships for a series of peptidomimetic antimicrobial prodrugs containing glutamine analogues.

  2003cited by this paper
• MtsABC Is Important for Manganese and Iron Transport, Oxidative Stress Resistance, and Virulence of Streptococcus pyogenes

  2003cited by this paper
• Acquisition of Mn(II) in Addition to Fe(II) Is Required for Full Virulence of Salmonella enterica Serovar Typhimurium

  2002influential reference
• Structure and association of ATP-binding cassette transporter nucleotide-binding domains.

  2002cited by this paper
• Immunoproteome of Helicobacter pylori.

  2002cited by this paper
• Mapping of immunoreactive antigens of Francisella tularensis live vaccine strain

  2002cited by this paper
• A Glutamine Transport Gene, glnQ, Is Required for Fibronectin Adherence and Virulence of Group B Streptococci

  2002cited by this paper
• Identification of vaccine candidate antigens of Staphylococcus aureus by serological proteome analysis

  2002cited by this paper
• Identification of ABC transporters in vancomycin-resistant Enterococcus faecium as potential targets for antibody therapy.

  2002influential reference
• Proteome Analysis of Highly Immunoreactive Proteins of Helicobacter pylori

  2002cited by this paper
• Search for Potential Vaccine Candidate Open Reading Frames in the Bacillus anthracis Virulence Plasmid pXO1: In Silico and In Vitro Screening

  2002cited by this paper
• GroEL (Hsp60) of Clostridium difficile is involved in cell adherence.

  2001cited by this paper
• Application of High-Density Array-Based Signature-Tagged Mutagenesis To Discover Novel YersiniaVirulence-Associated Genes

  2001cited by this paper
• ABC transporters catalyzing carbohydrate uptake.

  2001cited by this paper
• Bacterial transporters for sulfate and organosulfur compounds.

  2001cited by this paper
• A Streptococcus pneumoniae pathogenicity island encoding an ABC transporter involved in iron uptake and virulence

  2001cited by this paper
• Molybdate transport.

  2001cited by this paper
• Role of ATP hydrolysis by UvrA and UvrB during nucleotide excision repair.

  2001cited by this paper
• Polyamine uptake systems in Escherichia coli.

  2001cited by this paper
• Immunization with Components of Two Iron Uptake ABC Transporters Protects Mice against Systemic Streptococcus pneumoniae Infection

  2001cited by this paper
• Peptides and ATP binding cassette peptide transporters.

  2001cited by this paper
• Translational regulation by ABC systems.

  2001cited by this paper
• A new family of high-affinity ABC manganese and zinc permeases.

  2001cited by this paper
• Bacterial ABC transporters of amino acids.

  2001cited by this paper
• ABC transporters and the export of capsular polysaccharides from gram-negative bacteria.

  2001cited by this paper
• The ABC of ABCS: a phylogenetic and functional classification of ABC systems in living organisms.

  2001cited by this paper
• ABC transporters: physiology, structure and mechanism--an overview.

  2001cited by this paper
• Multidrug transport by ATP binding cassette transporters: a proposed two-cylinder engine mechanism.

  2001cited by this paper
• The role of ABC transporters in antibiotic-producing organisms: drug secretion and resistance mechanisms.

  2001cited by this paper
• ABC transporter-mediated uptake of iron, siderophores, heme and vitamin B12.

  2001cited by this paper
• SoxR‐dependent response to oxidative stress and virulence of Erwinia chrysanthemi: the key role of SufC, an orphan ABC ATPase

  2001cited by this paper
• Immunization of Mice with Combinations of Pneumococcal Virulence Proteins Elicits Enhanced Protection against Challenge with Streptococcus pneumoniae

  2000cited by this paper
• Natural development of antibodies to pneumococcal surface protein A, pneumococcal surface adhesin A, and pneumolysin in relation to pneumococcal carriage and acute otitis media.

  2000cited by this paper
• Genetic Characterization of a Streptococcus mutans LraI Family Operon and Role in Virulence

  2000cited by this paper
• Intranasal Immunization of Mice with a Mixture of the Pneumococcal Proteins PsaA and PspA Is Highly Protective against Nasopharyngeal Carriage of Streptococcus pneumoniae

  2000cited by this paper
• Identification of an Immunodominant ABC Transporter in Methicillin-Resistant Staphylococcus aureusInfections

  2000cited by this paper
• The putative iron transport system SitABCD encoded on SPI1 is required for full virulence of Salmonella typhimurium

  2000cited by this paper
• Identification of Yersinia enterocolitica genes affecting survival in an animal host using signature‐tagged transposon mutagenesis

  1999cited by this paper
• The Yfe system of Yersinia pestis transports iron and manganese and is required for full virulence of plague

  1999cited by this paper
• Cloning and characterization of a gene encoding an antigenic membrane protein from Actinobacillus pleuropneumoniae with homology to ABC transporters.

  1999cited by this paper
• Subunit interactions in ABC transporters: towards a functional architecture.

  1999cited by this paper
• YbtP and YbtQ: two ABC transporters required for iron uptake in Yersinia pestis

  1999cited by this paper
• Identification of the znuA-Encoded Periplasmic Zinc Transport Protein of Haemophilus ducreyi

  1999cited by this paper
• Immunogenicity and protective efficacy of tuberculosis DNA vaccines encoding putative phosphate transport receptors.

  1999cited by this paper
• Use of primate model system to identify Chlamydia trachomatis protein antigens recognized uniquely in the context of infection.

  1999cited by this paper
• ABC transporters: bacterial exporters-revisited five years on.

  1999cited by this paper
• In vivo testing of an Enterococcus faecalis efaA mutant and use of efaA homologs for species identification.

  1998cited by this paper
• The Escherichia coli ATP‐binding cassette (ABC) proteins

  1998cited by this paper
• ATP-binding-cassette (ABC) transport systems: functional and structural aspects of the ATP-hydrolyzing subunits/domains.

  1998cited by this paper
• Staphylococcus aureus genetic loci impacting growth and survival in multiple infection environments

  1998cited by this paper
• Campylobacter jejuni 72Dz/92 cjaC gene coding 28 kDa immunopositive protein, a homologue of the solute‐binding components of the ABC transport system

  1998cited by this paper
• Surface-Associated Hsp60 Chaperonin of Legionella pneumophila Mediates Invasion in a HeLa Cell Model

  1998cited by this paper
• Large-scale identification of virulence genes from Streptococcus pneumoniae.

  1998cited by this paper
• Identification and characterization of a basic cell surface-located protein from Lactobacillus fermentum BR11

  1997cited by this paper
• Identification and transcriptional analysis of a Treponema pallidum operon encoding a putative ABC transport system, an iron-activated repressor protein homolog, and a glycolytic pathway enzyme homolog.

  1997cited by this paper
• Identification of Staphylococcus aureus virulence genes in a murine model of bacteraemia using signature‐tagged mutagenesis

  1997cited by this paper
• Identification and characterization of Brucella ovis immunogenic proteins using two‐dimensional electrophoresis and immunoblotting

  1997cited by this paper
• Three different putative phosphate transport receptors are encoded by the Mycobacterium tuberculosis genome and are present at the surface of Mycobacterium bovis BCG

  1997cited by this paper
• Requirement for genes with homology to ABC transport systems for attachment and virulence of Agrobacterium tumefaciens

  1996cited by this paper
• Sequence heterogeneity of PsaA, a 37-kilodalton putative adhesin essential for virulence of Streptococcus pneumoniae

  1996cited by this paper
• Analysis of the pesticin receptor from Yersinia pestis: role in iron-deficient growth and possible regulation by its siderophore

  1995cited by this paper
• FimA, a major virulence factor associated with Streptococcus parasanguis endocarditis

  1995cited by this paper
• The crystal structures of the oligopeptide-binding protein OppA complexed with tripeptide and tetrapeptide ligands.

  1995cited by this paper
• Simultaneous identification of bacterial virulence genes by negative selection.

  1995cited by this paper
• Porin activity and sequence analysis of a 31-kilodalton Treponema pallidum subsp. pallidum rare outer membrane protein (Tromp1)

  1995cited by this paper
• The structural basis of sequence-independent peptide binding by OppA protein.

  1994cited by this paper
• Simultaneous exploitation of different peptide permeases by combinations of synthetic peptide smugglins can lead to enhanced antibacterial activity.

  1990cited by this paper
• Microbiology. Synthesizing designer drugs.

  1987cited by this paper
• Design and synthesis of peptide derivatives of a 3-deoxy-D-manno-2-octulosonic acid (KDO) analogue as novel antibacterial agents acting upon lipopolysaccharide biosynthesis.

  1987cited by this paper
• Synthesizing designer drugs

  1987cited by this paper
• A new class of synthetic antibacterials acting on lipopolysaccharide biosynthesis

  1987cited by this paper
• Peptides and micro-organisms.

  1976cited by this paper
• Transport of impermeant substances in E. coli by way of oligopeptide permease.

  1973cited by this paper
• Illicit transport: the oligopeptide permease.

  1973cited by this paper
• Identification and Characterization of a Brucella abortus ATP-Binding Cassette Transporter Homolog to Rhizobium meliloti ExsA and Its Role in Virulence and Protection in Mice

  year unknowncited by this paper

• PurK, N5-Carboxyaminoimidazole Ribonucleotide Synthetase, an Exocrine Protein Induced by Potato Plants, Influences the Virulence Through Motility Modulation in Pectobacterium brasiliense NJAU180

  2026cites this paper
• SPD_1629 is a uracil transporter and is crucial for pneumococcal fitness and pathogenesis in vivo.

  2025cites this paper
• Identification of cross-reactive vaccine antigen candidates in Gram-positive ESKAPE pathogens through subtractive proteome analysis using opsonic sera

  2025cites this paper
• The Evolution of ABC Importers.

  2025cites this paper
• Psychrobacter Infections in Humans—A Narrative Review of Reported Cases

  2025cites this paper
• Characterization of Extracellular Vesicles from Streptococcus thermophilus 065 and Their Potential to Modulate the Immune Response

  2025cites this paper
• Vaginal pharmacomicrobiomics modulates risk of persistent and recurrent bacterial vaginosis

  2025influential citation
• Identification and evaluation of novel antigens PykA, CPE1060 and Mbp as G-type Clostridium perfringens subunit vaccines.

  2025cites this paper
• A defined bacterial consortium and spatial transcriptomics highlight the complex interaction between Campylobacter jejuni and the murine intestine

  2025cites this paper
• RNA thermometers are widespread upstream of ABC transporter genes in bacteria

  2024cites this paper
• HbpA from Glaesserella parasuis induces an inflammatory response in 3D4/21 cells by activating the MAPK and NF-κB signalling pathways and protects mice against G. parasuis when used as an immunogen

  2024cites this paper
• Burkholderia pseudomallei Complex Subunit and Glycoconjugate Vaccines and Their Potential to Elicit Cross-Protection to Burkholderia cepacia Complex

  2024cites this paper
• Genome wide structural prediction of ABC transporter systems in Bacillus subtilis

  2024cites this paper
• Bioinformatic Analysis of Sulfotransferases from an Unexplored Gut Microbe, Sutterella wadsworthensis 3_1_45B: Possible Roles towards Detoxification via Sulfonation by Members of the Human Gut Microbiome

  2024cites this paper
• Secretome analysis and virulence assessment in Abiotrophia defectiva

  2024cites this paper
• Unraveling the molecular dynamics of Pseudomonas aeruginosa biofilms at the air-liquid interface.

  2024cites this paper
• Identification and Functional Annotation of Hypothetical Proteins of Pan-Drug-Resistant Providencia rettgeri Strain MRSN845308 Toward Designing Antimicrobial Drug Targets

  2024cites this paper
• Wildfire Ashes from the Wildland-Urban Interface Alter Vibrio vulnificus Growth and Gene Expression.

  2024cites this paper
• Detergents with Scalable Properties Identify Noncanonical Lipopolysaccharide Binding to Bacterial Inner Membrane Proteins

  2024cites this paper
• 16S rRNA female reproductive microbiome investigation reveals Dalfopristin, Clorgyline, and Hydrazine as potential therapeutics for the treatment of bacterial vaginosis.

  2024cites this paper
• Transcriptional profiling of extraintestinal Escherichia coli exposed to cranberry pomace extracts alone or in combination with ceftriaxone

  2023influential citation
• Transcriptional Response of Pectobacterium carotovorum to Cinnamaldehyde Treatment

  2023cites this paper
• Rationalizing the Optimization of Detergents for Membrane Protein Purification.

  2023cites this paper
• Comprehensive genomic analysis of hypocholesterolemic probiotic Enterococcus faecium LR13 reveals unique proteins involved in cholesterol-assimilation

  2023cites this paper
• Discovery of Natural Bispecific Antibodies: Is Psoriasis Induced by a Toxigenic Corynebacterium simulans and Maintained by CIDAMPs as Autoantigens?

  2023cites this paper
• Structures and coordination chemistry of transporters involved in manganese and iron homeostasis.

  2023cites this paper
• Proteomic analysis to unravel the biochemical mechanisms triggered by Bacillus toyonensis SFC 500-1E under chromium(VI) and phenol stress

  2023cites this paper
• The man, the plant, and the insect: shooting host specificity determinants in Serratia marcescens pangenome

  2023cites this paper
• Transcriptome analysis reveals the underlying mechanism for over-accumulation of alkaline protease in Bacillus licheniformis.

  2023cites this paper
• Role of Metabolic Adaptation of Streptococcus suis to Host Niches in Bacterial Fitness and Virulence

  2023cites this paper
• Hemin availability induces coordinated DNA methylation and gene expression changes in Porphyromonas gingivalis

  2023cites this paper
• In silico functional and structural characterization revealed virulent proteins of Francisella tularensis strain SCHU4

  2022cites this paper
• Reduced and Nonreduced Genomes in Paraburkholderia Symbionts of Social Amoebas

  2022cites this paper
• Streptococcus mutans glutamate binding protein (GlnH) as antigen target for a mucosal anti-caries vaccine

  2022cites this paper
• Isoquinoline Antimicrobial Agent: Activity against Intracellular Bacteria and Effect on Global Bacterial Proteome

  2022cites this paper
• Biochemical and Molecular Mechanisms of Antibiotic Resistance in Salmonella spp.

  2022cites this paper
• The emergence of metal oxide nanoparticles (NPs) as a phytomedicine: A two-facet role in plant growth, nano-toxicity and anti-phyto-microbial activity.

  2022cites this paper
• Functional Annotation of Hypothetical Proteins From the Enterobacter cloacae B13 Strain and Its Association With Pathogenicity

  2022cites this paper
• Unique mechanistic insights into pathways associated with the synergistic activity of polymyxin B and caspofungin against multidrug-resistant Klebsiella pneumoniae

  2022cites this paper
• Hemin availability induces coordinated DNA methylation and gene expression changes in Porphyromonas gingivalis

  2022cites this paper
• Distinct Potentially Adaptive Accumulation of Truncation Mutations in Salmonella enterica serovar Typhi and Salmonella enterica serovar Paratyphi A

  2022cites this paper
• Immunomodulatory effect of mycobacterial outer membrane vesicles coated nanoparticles

  2022cites this paper
• Comparative genomics support reduced-genome Paraburkholderia symbionts of Dictyostelium discoideum amoebas are ancestrally adapted professional symbionts

  2022cites this paper
• Metal Ion Periplasmic-Binding Protein YfeA of Glaesserella parasuis Induces the Secretion of Pro-Inflammatory Cytokines of Macrophages via MAPK and NF-κB Signaling through TLR2 and TLR4

  2022cites this paper
• Bacterial Community in Cold Surge-Caused Sea Ice Differs From Seawater in Mid-Latitude Region: A Case Study in Aoshan Bay, Southern Yellow Sea

  2022cites this paper
• Involvement of a putative ATP-Binding Cassette (ABC) Involved in manganese transport in virulence of Listeria monocytogenes

  2022cites this paper
• Streptococcus suis TrpX is part of a tryptophan uptake system, and its expression is regulated by a T-box regulatory element

  2022cites this paper
• Transcriptome analysis revealed transporter proteins role in the growth of Labrenzia sp. PO1 and SY1

  2021cites this paper
• How Zinc-Binding Systems, Expressed by Human Pathogens, Acquire Zinc from the Colonized Host Environment: A Critical Review on Zincophores

  2021cites this paper
• ABC Transporters and Group Translocation

  2021cites this paper
• Reverse Microbiomics: A New Reverse Dysbiosis Analysis Strategy and Its Usage in Prediction of Autoantigens and Virulent Factors in Dysbiotic Gut Microbiomes From Rheumatoid Arthritis Patients

  2021cites this paper
• Genetic Determinants in Salmonella enterica Serotype Typhimurium Required for Overcoming In Vitro Stressors in the Mimicking Host Environment

  2021cites this paper
• Context-aware genomic surveillance reveals hidden transmission of a carbapenemase-producing Klebsiella pneumoniae

  2021cites this paper
• Biophysical analysis of the Mycobacteria tuberculosis peptide binding protein DppA reveals a stringent peptide binding pocket.

  2021cites this paper
• Virtual Screening to Identify Protein Targets of Aggregatibacter Actinomycetemcomitans Interacting with Emodin

  2021cites this paper
• Proteins from the core genome of Corynebacterium ulcerans respond for pathogenicity and reveal promising vaccine targets for diphtheria.

  2021cites this paper
• Reannotation of mycoplasma hyopneumoniae hypothetical proteins revealed novel potential virulence factors.

  2021cites this paper
• Study of silver nanoparticle effects on some molecular responses and metabolic pathways of Phytophthora parasitica

  2021cites this paper
• Detection of Carbapenems Resistant K-mer Sequences in Bacteria of Critical Priority by the World Health Organization (Pseudomonas aeruginosa and Acinetobacter baumannii)

  2020cites this paper
• A review of bacterial zoonoses and antimicrobial resistant (AMR) on grouper fish (epinepholus sp.)

  2020cites this paper
• Signs of biofilm formation in the genome of Labrenzia sp. PO1

  2020cites this paper
• Inactivation of the htpsA gene affects capsule development and pathogenicity of Streptococcus suis

  2020cites this paper
• A compromised developmental trajectory of the infant gut microbiome and metabolome in atopic eczema

  2020cites this paper
• Multitask ATPases (NBDs) of bacterial ABC importers type I and their interspecies exchangeability

  2020cites this paper
• Identification of residues for chaperone-like activity of OppA protein in Yersinia pseudotuberculosis

  2020cites this paper
• Iron Pathways and Iron Chelation Approaches in Viral, Microbial, and Fungal Infections

  2020cites this paper
• Complementation of the Mycoplasma synoviae MS-H vaccine strain with wild-type oppF1 influences its growth characteristics

  2020cites this paper
• Dynamic interactions within the host-associated microbiota cause tumor formation in the basal metazoan Hydra

  2020cites this paper
• Crystal structure and pathophysiological role of the pneumococcal nucleoside-binding protein PnrA.

  2020cites this paper
• Live attenuated pertussis vaccine BPZE1 induces a broad antibody response in humans.

  2020cites this paper
• Vaccinomics to Design a Novel Single Chimeric Subunit Vaccine for Broad-Spectrum Immunological Applications targeting Nosocomial Enterobacteriaceae Pathogens.

  2020cites this paper
• Immunization with the basic membrane protein (BMP) family ABC transporter elicits protection against Enterococcus faecium in a murine infection model.

  2020cites this paper
• Transcriptomic Analysis of the Brucella melitensis Rev.1 Vaccine Strain in an Acidic Environment: Insights Into Virulence Attenuation

  2019cites this paper
• Crystal structure of SpuE-Spermidine in complex with ScFv5

  2019cites this paper
• In-silico subtractive proteomic analysis approach for therapeutic targets in MDR Salmonella enterica sub sp. Enterica serovar Typhi str. CT18.

  2019cites this paper
• Comparative assessment of the therapeutic drug targets of C. botulinum ATCC 3502 and C. difficile str. 630 using in silico subtractive proteomics approach

  2019cites this paper
• The scfCDE Operon Encodes a Predicted ABC Importer Required for Fitness and Virulence during Group A Streptococcus Invasive Infection

  2019cites this paper
• In silico characterization of hypothetical proteins from Orientia tsutsugamushi str. Karp uncovers virulence genes

  2019cites this paper
• Temporal proteomic profiling reveals changes that support Burkholderia biofilms.

  2019cites this paper
• Rv1273c, an ABC transporter of Mycobacterium tuberculosis promotes mycobacterial intracellular survival within macrophages via modulating the host cell immune response.

  2019cites this paper
• Bioinformatic Exploration of Metal-Binding Proteome of Zoonotic Pathogen Orientia tsutsugamushi

  2019cites this paper
• Molecular Basis of Unexpected Specificity of ABC Transporter-Associated Substrate-Binding Protein DppA from Helicobacter pylori

  2019cites this paper
• Structures of the substrate-binding protein YfeA in apo and zinc-reconstituted holo forms

  2019cites this paper
• Structural and Functional Annotation of Conserved Virulent Hypothetical Proteins in Chlamydia Trachomatis: An In-Silico Approach

  2019cites this paper
• Zinc-Induced Immune Anti-Bacterial Vaccine Activity in Bacterial Cell Walls Against Gram-Positive and Gram-Negative Bacteria

  2019cites this paper
• Mutation of oppF gene in the Mycoplasma synoviae MS-H vaccine strain and its implication for differential serological responses to vaccination versus field challenge.

  2019cites this paper
• Structural insights into the substrate specificity of SP_0149, the substrate-binding protein of a methionine ABC transporter from Streptococcus pneumoniae.

  2019cites this paper
• An in silico approach towards identification of virulence factors in red complex pathogens targeted by reserpine

  2019cites this paper
• Characterization of bacteriocin ABC transporter ATP-binding protein produced by a newly isolated Enterococcus casseliflavus MI001 strain

  2019cites this paper
• Quantitative Proteomic Analyses of a Pathogenic Strain and Its Highly Passaged Attenuated Strain of Mycoplasma hyopneumoniae

  2019cites this paper
• Proteomics of Extracellular Vesicles Produced by Granulicatella Species that cause Infective Endocarditis

  2019cites this paper
• Patulin interference with ATP binding cassette transferring auto inducer −2 in Salmonella typhi and biofilm inhibition via quorum sensing

  2019cites this paper
• DNA Vaccines Against Mycoplasma Elicit Humoral Immune Responses in Ostriches

  2019cites this paper
• IMUNOPROFILAKSIS DAN IMUNOTERAPI BAKTERI STAPHYLOCOCCUS AUREUS

  2019cites this paper
• Millet-based supplement restored microbiota diversity of acute undernourished pigs

  2019cites this paper
• Immune Response of BALB/c Mice toward Putative Calcium Transporter Recombinant Protein of Trichomonas vaginalis

  2019cites this paper
• Preliminary X-ray crystallographic studies on the Helicobacter pylori ABC transporter glutamine-binding protein GlnH.

  2019cites this paper
• Genomic analysis of Indian strains of Salmonella enterica subsp. enterica serovar Typhi indicates novel genetic repertoire for pathogenicity and adaptations

  2019cites this paper
• Increased growth rate and amikacin resistance of Salmonella enteritidis after one‐month spaceflight on China’s Shenzhou‐11 spacecraft

  2019cites this paper
• Genetic determinants in Salmonella enterica serotype Typhimurium required for overcoming stressors in the host environment

  2019cites this paper