Acquisition of Mn(II) in Addition to Fe(II) Is Required for Full Virulence of Salmonella enterica Serovar Typhimurium

No abstract is available for this paper.

• Publication year

  2002

• Venue

  Infection and Immunity

• Publication date

  2002-11-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/IAI.70.11.6032-6042.2002PMID 12379679PMCID PMC130432
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• A new family of high-affinity ABC manganese and zinc permeases.

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  2000influential reference
• The putative iron transport system SitABCD encoded on SPI1 is required for full virulence of Salmonella typhimurium

  2000cited by this paper
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  2000cited by this paper
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  2000cited by this paper
• Iron metabolism in pathogenic bacteria.

  2000influential reference
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  2000cited by this paper
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  2000cited by this paper
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  1999influential reference
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  1998cited by this paper
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  1997cited by this paper
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  1997cited by this paper
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• Contribution of TonB- and Feo-mediated iron uptake to growth of Salmonella typhimurium in the mouse

  1996influential reference
• The Ity/Lsh/Bcg locus: natural resistance to infection with intracellular parasites is abrogated by disruption of the Nramp1 gene

  1995cited by this paper
• Molecular identification of an ABC transporter complex for manganese: analysis of a cyanobacterial mutant strain impaired in the photosynthetic oxygen evolution process.

  1995cited by this paper
• Haplotype mapping and sequence analysis of the mouse Nramp gene predict susceptibility to infection with intracellular parasites.

  1994cited by this paper
• Characterization of the ferrous iron uptake system of Escherichia coli

  1993cited by this paper
• Intracellular replication is essential for the virulence of Salmonella typhimurium.

  1991cited by this paper
• Resistance of inbred mice to Salmonella typhimurium.

  1972cited by this paper

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  2024cites this paper
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• Structures and coordination chemistry of transporters involved in manganese and iron homeostasis.

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• Manganese Utilization in Salmonella Pathogenesis: Beyond the Canonical Antioxidant Response

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• The emerging role of bacterial regulatory RNAs in disease.

  2022cites this paper
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