Brain gadolinium deposition after administration of gadolinium-based contrast agents

No abstract is available for this paper.

• Publication year

  2015

• Venue

  Japanese Journal of Radiology

• Publication date

  Unknown publication date

• Fields of study

  Medicine

• Identifiers
  DOI 10.1007/s11604-015-0503-5PMID 26608061
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Progressive increase of T1 signal intensity in the dentate nucleus and globus pallidus on unenhanced T1-weighted MR images in the pediatric brain exposed to multiple doses of gadolinium contrast.

  2016cited by this paper
• Increasing signal intensity within the dentate nucleus and globus pallidus on unenhanced T1W magnetic resonance images in patients with relapsing-remitting multiple sclerosis: correlation with cumulative dose of a macrocyclic gadolinium-based contrast agent, gadobutrol

  2016cited by this paper
• Gadolinium-based Contrast Agent Accumulates in the Brain Even in Subjects without Severe Renal Dysfunction: Evaluation of Autopsy Brain Specimens with Inductively Coupled Plasma Mass Spectroscopy.

  2015cited by this paper
• High-Signal Intensity in the Dentate Nucleus and Globus Pallidus on Unenhanced T1-Weighted Images: Evaluation of the Macrocyclic Gadolinium-Based Contrast Agent Gadobutrol

  2015cited by this paper
• Gadolinium retention in the dentate nucleus and globus pallidus is dependent on the class of contrast agent.

  2015cited by this paper
• Intracranial Gadolinium Deposition after Contrast-enhanced MR Imaging.

  2015influential reference
• Residual or retained gadolinium: practical implications for radiologists and our patients.

  2015cited by this paper
• What Evidence Is There That Gadobutrol Causes Increasing Signal Intensity within the Dentate Nucleus and Globus Pallidus on Unenhanced T1W MRI in Patients with RRMS?

  2015cited by this paper
• T1-Weighted Hypersignal in the Deep Cerebellar Nuclei After Repeated Administrations of Gadolinium-Based Contrast Agents in Healthy Rats

  2015cited by this paper
• Hyperintense Dentate Nuclei on T1-Weighted MRI: Relation to Repeat Gadolinium Administration

  2015cited by this paper
• Gadodiamide and Dentate Nucleus T1 Hyperintensity in Patients With Meningioma Evaluated by Multiple Follow-Up Contrast-Enhanced Magnetic Resonance Examinations With No Systemic Interval Therapy.

  2015cited by this paper
• Increased Signal Intensity in the Dentate Nucleus on Unenhanced T1-Weighted Images After Gadobenate Dimeglumine Administration

  2015cited by this paper
• Gadobenate Dimeglumine Administration and Nephrogenic Systemic Fibrosis: Is There a Real Risk in Patients with Impaired Renal Function?

  2015cited by this paper
• Gadolinium-associated plaques: a new, distinctive clinical entity.

  2015cited by this paper
• High T1 Signal Intensity in Dentate Nucleus after Multiple Injections of Linear Gadolinium Chelates.

  2015cited by this paper
• High Signal Intensity in Dentate Nucleus on Unenhanced T1-weighted MR Images: Association with Linear versus Macrocyclic Gadolinium Chelate Administration.

  2015cited by this paper
• Commentary on T1-Weighted Hypersignal in the Deep Cerebellar Nuclei After Repeated Administrations of Gadolinium-Based Contrast Agents in Healthy Rats: Difference Between Linear and Macrocyclic Agents.

  2015cited by this paper
• Revisiting the risks of MRI with Gadolinium based contrast agents—review of literature and guidelines

  2015cited by this paper
• High Signal Intensity in Globus Pallidus and Dentate Nucleus on Unenhanced T1-weighted MR Images: Evaluation of Two Linear Gadolinium-based Contrast Agents.

  2015cited by this paper
• High signal intensity in the dentate nucleus and globus pallidus on unenhanced T1-weighted MR images: relationship with increasing cumulative dose of a gadolinium-based contrast material.

  2014cited by this paper
• Application of Extracellular Gadolinium-based MRI Contrast Agents and the Risk of Nephrogenic Systemic Fibrosis

  2014cited by this paper
• Progressive Increase of T1 Signal Intensity of the Dentate Nucleus on Unenhanced Magnetic Resonance Images Is Associated With Cumulative Doses of Intravenously Administered Gadodiamide in Patients With Normal Renal Function, Suggesting Dechelation

  2014cited by this paper
• Nephrogenic systemic fibrosis and gadolinium-based contrast media: updated ESUR Contrast Medium Safety Committee guidelines

  2013influential reference
• High frequency of calcification in basal ganglia on brain computed tomography images in Japanese older adults

  2013cited by this paper
• Identification of mineral deposits in the brain on radiological images: a systematic review

  2012cited by this paper
• Intracranial lesions with high signal intensity on T1-weighted MR images: differential diagnosis.

  2012cited by this paper
• Lollipop lesions in nephrogenic systemic fibrosis mimicking a deep fungal infection.

  2012cited by this paper
• Nephrogenic systemic fibrosis.

  2012cited by this paper
• Cover Quizlet: Cover Quizlet

  2012cited by this paper
• MRI contrast agents: Basic chemistry and safety

  2012influential reference
• The Developmental History of the Gadolinium Chelates as Intravenous Contrast Media for Magnetic Resonance

  2011influential reference
• Findings of osseous sclerotic bodies: a unique sequence of cutaneous bone formation in nephrogenic systemic fibrosis

  2011cited by this paper
• Quantification of gadolinium in fresh skin and serum samples from patients with nephrogenic systemic fibrosis.

  2011cited by this paper
• Hyperintense dentate nucleus on unenhanced T1-weighted MR images is associated with a history of brain irradiation.

  2011cited by this paper
• Nephrogenic systemic fibrosis

  2010cited by this paper
• Gadolinium released from MR contrast agents is deposited in brain tumors: in situ demonstration using scanning electron microscopy with energy dispersive X-ray spectroscopy

  2010cited by this paper
• Role of thermodynamic and kinetic parameters in gadolinium chelate stability

  2009cited by this paper
• Incorporation of excess gadolinium into human bone from medical contrast agents.

  2009cited by this paper
• Multiple sclerosis: hyperintense dentate nucleus on unenhanced T1-weighted MR images is associated with the secondary progressive subtype.

  2009cited by this paper
• Sclerotic bodies in nephrogenic systemic fibrosis: a new histopathologic finding

  2009cited by this paper
• Primer on gadolinium chemistry

  2009cited by this paper
• Efficiency, thermodynamic and kinetic stability of marketed gadolinium chelates and their possible clinical consequences: a critical review

  2008cited by this paper
• Preclinical investigation to compare different gadolinium-based contrast agents regarding their propensity to release gadolinium in vivo and to trigger nephrogenic systemic fibrosis-like lesions

  2008cited by this paper
• Stability of Gadolinium-Based Magnetic Resonance Imaging Contrast Agents in Human Serum at 37°C

  2008cited by this paper
• Gadolinium is detectable within the tissue of patients with nephrogenic systemic fibrosis.

  2007cited by this paper
• Gadolinium deposition in nephrogenic fibrosing dermopathy.

  2007cited by this paper
• Metal transporters in intestine and brain: their involvement in metal-associated neurotoxicities

  2007cited by this paper
• Nephrogenic systemic fibrosis: risk factors and incidence estimation.

  2007cited by this paper
• Comparison of Gd(DTPA-BMA) (Omniscan) Versus Gd(HP-DO3A) (ProHance) Relative to Gadolinium Retention in Human Bone Tissue by Inductively Coupled Plasma Mass Spectroscopy

  2006cited by this paper
• Nephrogenic systemic fibrosis: suspected causative role of gadodiamide used for contrast-enhanced magnetic resonance imaging.

  2006cited by this paper
• Gadolinium--a specific trigger for the development of nephrogenic fibrosing dermopathy and nephrogenic systemic fibrosis?

  2006cited by this paper
• Human comparative study of zinc and copper excretion via urine after administration of magnetic resonance imaging contrast agents.

  2005cited by this paper
• Comparison of Gd DTPA-BMA (Omniscan) versus Gd HP-DO3A (ProHance) Retention in Human Bone Tissue by Inductively Coupled Plasma Atomic Emission Spectroscopy

  2004cited by this paper
• Scleromyxoedema-like cutaneous diseases in renal-dialysis patients.

  2000cited by this paper
• Human in vivo comparative study of zinc and copper transmetallation after administration of magnetic resonance imaging contrast agents.

  1996cited by this paper
• Biodistribution of Radiolabeled, Formulated Gadopentetate, Gadoteridol, Gadoterate, and Gadodiamide in Mice and Rats

  1995cited by this paper
• Dose-dependent biodistribution of [153Gd]Gd(acetate)n in mice.

  1993cited by this paper
• Dissociation of gadolinium chelates in mice: relationship to chemical characteristics.

  1992cited by this paper
• Comparison of the biodistribution of 153Gd-labeled Gd(DTPA)2-, Gd(DOTA)-, and Gd(acetate)n in mice.

  1988cited by this paper
• Work in progress: potential oral and intravenous paramagnetic NMR contrast agents.

  1983cited by this paper

• Hepatic organic anion transporting polypeptides (OATPs) as MRI reporter proteins

  2026cites this paper
• Accuracy of Tumor Surveillance of Pediatric Adamantinomatous Craniopharyngioma Using Noncontrast Brain MRI

  2025cites this paper
• Blood-brain barrier water exchange in relation to amyloid, cognition and cerebrovascular burden

  2025cites this paper
• Squared diffusion-weighted imaging for improving the detection of clinically significant prostate cancer

  2025cites this paper
• Enhanced detection of glioblastoma vasculature with superparamagnetic iron oxide nanoparticles and MRI

  2025cites this paper
• Skin-Related Adverse Reactions in Gadolinium-Based Contrast Agents-Induced Hypersensitivity: A Systematic Review of the Literature

  2025cites this paper
• Protamine-1 encoded recombinant adeno-associated virus for enhanced brain magnetic resonance imaging.

  2025cites this paper
• Gadopiclenol Versus Gadoterate Meglumine for Pediatric Brain MRI: An Intraindividual Comparison of Contrast Enhancement.

  2025cites this paper
• Identifying a potential role of immune cells in gadolinium deposition within the brain

  2025cites this paper
• A Review on Novel Applications of Nanoparticles in Pediatric Oncology

  2025cites this paper
• The Value of Using Quantitative MRI based on Synthetic Acquisition and Apparent Diffusion Coefficient to Monitor Multiple Sclerosis Lesion Activity.

  2025cites this paper
• Taylor dispersion analysis for measurement of diffusivity and size of gadolinium-based contrast agents.

  2024cites this paper
• New Insights into the Toxicity of Lanthanides with Functional Genomics.

  2024cites this paper
• Tracking the distribution of persistent and mobile wastewater-derived substances in the southern and central North Sea using anthropogenic gadolinium from MRI contrast agents as a far-field tracer.

  2024cites this paper
• Into the deep: Exploring the molecular mechanisms of hyperactive behaviour induced by three rare earth elements in early life-stages of the deep-sea scavenging amphipod Tmetonyx cicada (Lysianassidae).

  2024cites this paper
• Contrast‐free dynamic susceptibility contrast using sinusoidal and bolus oxygenation challenges

  2024cites this paper
• Evaluation of signal intensity changes in dentate nucleus and globus pallidus on magnetic resonance imaging after intrathecal gadolinium-based contrast agent administration.

  2024cites this paper
• The Application, Safety, and Recent Developments of Commonly Used Gadolinium-Based Contrast Agents in MRI: A Scoping Review

  2024cites this paper
• The Glymphatic System in Humans: Investigations With Magnetic Resonance Imaging

  2023cites this paper
• Heavily Gd-Doped Non-Toxic Cerium Oxide Nanoparticles for MRI Labelling of Stem Cells

  2023cites this paper
• Gadolinium-Based Contrast Agents and Free Gadolinium Inhibit Differentiation and Activity of Bone Cell Lineages

  2023cites this paper
• Effects of gadolinium (Gd) and a Gd-based contrast agent (GBCA) on early life stages of zebrafish (Danio rerio).

  2023cites this paper
• Nano-imaging agents for brain diseases: Environmentally responsive imaging and therapy

  2023cites this paper
• Brand ferumoxytol vs. generic ferumoxytol comparison across two dosing regimens: a cardiac MRI image quality study

  2023cites this paper
• A Comprehensive Overview of the Efficacy and Safety of Gadopiclenol: A New Contrast Agent for MRI of the CNS and Body

  2023cites this paper
• Understanding the biological behavior of lanthanides and actinides through omics approaches

  2023cites this paper
• Gadolinium-based contrast agents suppress adipocyte differentiation in 3T3-L1 cells.

  2023cites this paper
• Gadolinium contrast agents- challenges and opportunities of a multidisciplinary approach: Literature review

  2023cites this paper
• Glymphatic Magnetic Resonance Imaging: Part I—Methodologies for Evaluation of the Glymphatic System

  2023cites this paper
• Intracerebral gadolinium deposition following blood–brain barrier disturbance in two different mouse models

  2023cites this paper
• Comparison of the biological effects of gadodiamide (Omniscan) and gadoteridol (ProHance) by means of multi-organ and plasma metabolomics.

  2023cites this paper
• Brain MRI and clinical exam findings in women with multiple gadolinium-based contrast agent (GBCA) exposures due to screening breast MRIs.

  2022cites this paper
• Gadolinium based contrast agents (GBCAs): Uniqueness, aquatic toxicity concerns, and prospective remediation.

  2022cites this paper
• Ferumoxytol-Enhanced MRI in Children and Young Adults: State of the Art.

  2022cites this paper
• Gadolinium-based contrast agent accelerates the migration of astrocyte via integrin αvβ3 signaling pathway

  2022cites this paper
• American Society of Regional Anesthesia and Pain Medicine contrast shortage position statement

  2022cites this paper
• The Effect of Gadolinium-Based Contrast Agents on Longitudinal Changes of Magnetic Resonance Imaging Signal Intensities and Relaxation Times in the Aging Rat Brain

  2022cites this paper
• Applications of nanoparticles in cardiovascular imaging and therapeutics

  2022cites this paper
• The effect of gadolinium-based contrast-agents on automated brain atrophy measurements by FreeSurfer in patients with multiple sclerosis

  2022cites this paper
• Delineating toxicity mechanisms associated with MRI contrast enhancement through a multidimensional toxicogenomic profiling of gadolinium.

  2022cites this paper
• Awareness of Gadolinium Toxicity Among Non-radiologists in Saudi Arabia

  2022influential citation
• The Spreads and the Uniqueness of the Controversial Toxic Pharmaceutic Contrast Agents and Their Remediation.

  2022cites this paper
• Gadolinium Retention after Contrast-Enhanced Magnetic Resonance Imaging: A Narratative Review

  2022influential citation
• Does Gadolinium Deposition Lead to Metabolite Alteration in the Dentate Nucleus? An MRS Study in Patients with MS

  2022cites this paper
• A Contrast Examination of Proinflammatory Effects on Kidney Function for γ-Fe2O3 NP and Gadolinium Dimeglumine

  2021cites this paper
• The Use of Contrast Agents in Interventional Pain Procedures: A Multispecialty and Multisociety Practice Advisory on Nephrogenic Systemic Fibrosis, Gadolinium Deposition in the Brain, Encephalopathy After Unintentional Intrathecal Gadolinium Injection, and Hypersensitivity Reactions

  2021cites this paper
• Effects of Gadolinium Deposits in the Cerebellum: Reviewing the Literature from In Vitro Laboratory Studies to In Vivo Human Investigations

  2021cites this paper
• Use of Intravenous Contrast During Pregnancy and Lactation

  2021cites this paper
• Fluorescent chitosan-based nanohydrogels and encapsulation of gadolinium MRI contrast agent for magneto-optical imaging

  2021cites this paper
• Chemistry, Physicochemical Properties and Pharmacokinetics of Gadolinium-Based Contrast Agents

  2021cites this paper
• Evidence of high bioaccessibility of gadolinium-contrast agents in natural waters after human oral uptake.

  2021cites this paper
• Application of ICP-MS to the development of metal-based drugs and diagnostic agents: where do we stand?

  2021cites this paper
• Genome-wide toxicogenomic study of the lanthanides sheds light on the selective toxicity mechanisms associated with critical materials

  2021cites this paper
• Safety issues related to intravenous contrast agent use in magnetic resonance imaging

  2021cites this paper
• Gadolinium-based contrast agents in neurofibromatosis type 1 (Review)

  2021cites this paper
• The Use of Gadolinium in Musculoskeletal MRI—Time to Rethink?

  2021cites this paper
• Dentate Nucleus Signal Intensity Changes in Children with Adrenoleukodystrophy in Comparison to Primary Brain Tumor with and without Radiotherapy after Gadobutrol Administration

  2021cites this paper
• Comparison of unenhanced and contrast-enhanced 3 T magnetic resonance portovenography in children with extra hepatic portal venous obstruction

  2021cites this paper
• Interference of gadolinium dechelated from MR contrast agents by calcium signaling in neuronal cells of GnRH

  2020cites this paper
• Variations in native T1 values in patients with Duchenne muscular dystrophy with and without late gadolinium enhancement

  2020cites this paper
• Abbreviated and Ultrafast Breast MRI in Clinical Practice.

  2020cites this paper
• Limited Utility of Gadolinium Contrast Administration in Routine Multiple Sclerosis Surveillance

  2020cites this paper
• The Glymphatic System: A Review of the Challenges in Visualizing its Structure and Function with MR Imaging

  2020cites this paper
• Assessment of gadolinium deposition in the brain tissue of pediatric and adult congenital heart disease patients after contrast enhanced cardiovascular magnetic resonance

  2020cites this paper
• Benefits and Detriments of Gadolinium from Medical Advances to Health and Ecological Risks

  2020cites this paper
• Abbreviated magnetic resonance imaging in breast cancer: A systematic review of literature

  2020cites this paper
• Glymphatic imaging using MRI

  2020cites this paper
• Influence Blocking by Gadolinium in Calcium Diffusion on Synapse Model: A Monte Carlo Simulation Study

  2020cites this paper
• Multifunctional imaging of amyloid-beta peptides with a new gadolinium-based contrast agent in Alzheimer’s disease

  2020cites this paper
• Synthesis and in vivo behaviour of an exendin-4-based MRI probe capable of β-cell-dependent contrast enhancement in the pancreas.

  2020cites this paper
• A Microfluidic Platform to design Multimodal PEG - crosslinked Hyaluronic Acid Nanoparticles (PEG-cHANPs) for diagnostic applications

  2020cites this paper
• Investigation of potential adverse central nervous system effects after long term oral administration of gadolinium in mice

  2020cites this paper
• Rapid Detection of Gadolinium-Based Contrast Agents in Urine with a Chelated Europium Luminescent Probe.

  2020cites this paper
• Anthropogenic gadolinium in freshwater and drinking water systems

  2020cites this paper
• Ultra-High-b-Value Kurtosis Imaging for Noninvasive Tissue Characterization of Ovarian Lesions.

  2020cites this paper
• Ag2Te Quantum Dots as Contrast Agents for Near-Infrared Fluorescence and Computed Tomography Imaging

  2020cites this paper
• Influence Blocking by Gadolinium in Calcium Diffusion on Synapse Model: A Monte Carlo Simulation Study

  2020cites this paper
• Prediction of on-treatment disability worsening in RRMS with the MAGNIMS score

  2020cites this paper
• Cardiac Imaging for Coronary Heart Disease Risk Stratification in Chronic Kidney Disease.

  2020cites this paper
• Quantifying iron content in magnetic resonance imaging

  2019cites this paper
• Radiolabeled PET/MRI Nanoparticles for Tumor Imaging

  2019cites this paper
• 단축 자기공명영상검사를 이용한 유방암 검진

  2019cites this paper
• Safety of gadoterate meglumine in over 1600 children included in the prospective observational SECURE study

  2019influential citation
• Detection of recurrent brain tumors in children: No significant difference in sensitivity between unenhanced and contrast-enhanced MRI

  2019cites this paper
• Quantitative analysis of Gd in the protein content of the brain following single injection of gadolinium-based contrast agents (GBCAs) by size exclusion chromatography.

  2019cites this paper
• Ligand design strategies to increase stability of gadolinium-based magnetic resonance imaging contrast agents

  2019cites this paper
• Effects of gadolinium and gadolinium chelates on intracellular calcium signaling in sensory neurons.

  2019cites this paper
• MRI-biochemical follow up measurements of lumbar intervertebral disc in patients with leg length discrepancy: Is it possible to alter cartilage damage with conservative therapy?

  2019cites this paper
• Cumulative gadodiamide administration leads to brain gadolinium deposition in early MS

  2019influential citation
• Conservative gadolinium administration to patients with Duchenne muscular dystrophy: decreasing exposure, cost, and time, without change in medical management

  2019cites this paper
• Use and Safety of Gadolinium Based Contrast Agents in Pediatric MR Imaging

  2019cites this paper
• Studies of Helium Droplet Mass Spectrometry and Magnetic Nanoparticles

  2019cites this paper
• Imaging vascular calcification

  2019cites this paper
• EDTA Chelation Therapy for the Treatment of Neurotoxicity

  2019cites this paper
• Reductive microenvironment responsive gadolinium-based polymers as potential safe MRI contrast agents.

  2019cites this paper
• Magnetic resonance gadolinium-based contrast agent deposition in brain: status and progress

  2018cites this paper
• Gadolinium retention after administration of contrast agents based on linear chelators and the recommendations of the European Medicines Agency

  2018cites this paper
• Gadolinium as an MRI contrast agent.

  2018cites this paper
• The New Restrictions on the Use of Linear Gadolinium-based Contrast Agents in Japan

  2018cites this paper
• Contrast-enhanced cone-beam breast-CT (CBBCT): clinical performance compared to mammography and MRI

  2018cites this paper