Significance of taurine transporter (TauT) in homeostasis and its layers of regulation

Taurine (2-aminoethanesulfonic acid) contributes to homeostasis, mainly through its antioxidant and osmoregulatory properties. Taurine's influx and efflux are mainly mediated through the ubiquitous expression of the sodium/chloride-dependent taurine transporter, located on the plasma membrane. The significance of the taurine transporter has been shown in various organ malfunctions in taurine-transporter-null mice. The taurine transporter differentially responds to various cellular stimuli including ionic environment, electrochemical charge, and pH changes. The renal system has been used as a model to evaluate the factors that significantly determine the regulation of taurine transporter regulation.

• Publication year

  2020

• Venue

  Molecular Medicine Reports

• Publication date

  2020-07-09

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.3892/mmr.2020.11321PMID 32705197PMCID 7411481
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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