Functional TauT protects against acute kidney injury.

No abstract is available for this paper.

• Publication year

  2009

• Venue

  Journal of the American Society of Nephrology

• Publication date

  2009-06-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1681/ASN.2008050465PMID 19423693PMCID PMC2689910
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Regulation of PUMA-alpha by p53 in cisplatin-induced renal cell apoptosis.

  2006cited by this paper
• Regulation of PUMA-α by p53 in cisplatin-induced renal cell apoptosis

  2006cited by this paper
• The taurine transporter: mechanisms of regulation

  2006cited by this paper
• Neuronal cell death caused by inhibition of intracellular cholesterol trafficking is caspase dependent and associated with activation of the mitochondrial apoptosis pathway

  2006cited by this paper
• Prospective therapeutic applications of p53 inhibitors.

  2005cited by this paper
• Role of p53 in cisplatin-induced tubular cell apoptosis: dependence on p53 transcriptional activity.

  2004cited by this paper
• Characteristics of basal taurine release in the rat striatum measured by microdialysis

  2004cited by this paper
• Inflammatory cytokines in acute renal failure.

  2004influential reference
• Cell cycle regulation: repair and regeneration in acute renal failure.

  2004cited by this paper
• Deciphering the renal code: advances in conditional gene targeting.

  2004cited by this paper
• Ca2+-mediated Potentiation of the Swelling-induced Taurine Efflux from HeLa Cells: On the Role of Calmodulin and Novel Protein Kinase C Isoforms

  2004cited by this paper
• Cisplatin: mode of cytotoxic action and molecular basis of resistance

  2003cited by this paper
• Regulation of taurine transporter gene (TauT) by WT1

  2003cited by this paper
• TNFR2-mediated apoptosis and necrosis in cisplatin-induced acute renal failure.

  2003cited by this paper
• TNFR 2-mediated apoptosis and necrosis in cisplatin-induced acute renal failure

  2003cited by this paper
• TNF-alpha mediates chemokine and cytokine expression and renal injury in cisplatin nephrotoxicity.

  2002cited by this paper
• Kidney-Targeted Naked DNA Transfer by Retrograde Renal Vein Injection in Rats

  2002cited by this paper
• Cloning and characterization of the promoter region of the rat taurine transporter (TauT) gene.

  2002cited by this paper
• Protection Effects of Taurine Supplementation against Cisplatin-Induced Nephrotoxicity in Rats

  2002cited by this paper
• TNF-α mediates chemokine and cytokine expression and renal injury in cisplatin nephrotoxicity

  2002cited by this paper
• Disruption of the taurine transporter gene (taut) leads to retinal degeneration in mice

  2002cited by this paper
• Transcriptional Repression of Taurine Transporter Gene (TauT) by p53 in Renal Cells*

  2002cited by this paper
• Role of the increase in p21 in cisplatin-induced acute renal failure in rats.

  2001cited by this paper
• Regulation of TauT by cisplatin in LLC-PK1 renal cells

  2001cited by this paper
• Cloning and characterization of the promoter region of the rat taurine transporter (TauT) gene.

  2000cited by this paper
• The taurine transporter gene and its role in renal development

  2000cited by this paper
• Acute renal failure in the new millennium: time to consider combination therapy.

  2000cited by this paper
• Identification of promoter elements involved in adaptive regulation of the taurine transporter gene: role of cytosolic Ca2+ signaling.

  2000cited by this paper
• Induction of p21WAF1/CIP1/SDI1 in kidney tubule cells affects the course of cisplatin-induced acute renal failure.

  1998cited by this paper
• Clinical development of platinum complexes in cancer therapy: an historical perspective and an update.

  1998cited by this paper
• In vitro and in vivo evidence suggesting a role for iron in cisplatin-induced nephrotoxicity.

  1998cited by this paper
• Regulation of the taurine transporter gene in the S3 segment of the proximal tubule.

  1997cited by this paper
• Acute renal failure.

  1996cited by this paper
• Wild-type p53 transgenic mice exhibit altered differentiation of the ureteric bud and possess small kidneys.

  1996cited by this paper
• Somatic point mutations in the p53 gene of human tumors and cell lines: updated compilation

  1996cited by this paper
• Critical subcellular targets of cisplatin and related platinum analogs in rat renal proximal tubule cells.

  1995cited by this paper
• The Relative Roles of External Taurine Concentration and Medium Osmolality in the Regulation of Taurine Transport in LLC-PK1 and MDCK Cells

  1995cited by this paper
• Nephrotoxicity induced by cancer chemotherapy with special emphasis on cisplatin toxicity.

  1986cited by this paper
• Taurine deficiency in the developing cat: Persistence of the cerebellar external granule cell layer

  1985cited by this paper
• Taurine deficiency in the developing cat: persistence of the cerebellar external granule cell layer.

  1985cited by this paper
• Acute Renal Failure

  1960cited by this paper

• Molecular basis for substrate recognition and transport of mammalian taurine transporters

  2025cites this paper
• Molecular mechanisms attributed to colistin renal proximal tubular epithelial cytotoxicity

  2025cites this paper
• Taurine Deficiency Is a Hallmark of Injured Kidney Allografts

  2024cites this paper
• Direct Three-Dimensional Mass Spectrometry Imaging with Laser Ablation Remote Atmospheric Pressure Photoionization/Chemical Ionization

  2024cites this paper
• Untargeted metabolomics analysis of serum and urine unveils the protective effect of cilastatin on altered metabolic pathways during cisplatin-induced acute kidney injury.

  2024cites this paper
• NMR Metabolomics of Primary Ovarian Cancer Cells in Comparison to Established Cisplatin-Resistant and -Sensitive Cell Lines

  2024cites this paper
• Metabolomics Assessment of Volume Overload-Induced Heart Failure and Oxidative Stress in the Kidney

  2023cites this paper
• Metabolomics for the identification of early biomarkers of nephrotoxicity in a mouse model of cisplatin-induced acute kidney injury.

  2023cites this paper
• Metabolomics profiling distinctively identified end-stage renal disease patients from chronic kidney disease patients

  2023cites this paper
• TMT-based proteomics analysis of the cerebral cortex of TauT knockout rats

  2022cites this paper
• Taurine as a Natural Antioxidant: From Direct Antioxidant Effects to Protective Action in Various Toxicological Models

  2021cites this paper
• Ameliorative Effects of Gallic Acid on Cisplatin-Induced Nephrotoxicity in Rat Variations of Biochemistry, Histopathology, and Gene Expression

  2021influential citation
• Role of taurine, its haloamines and its lncRNA TUG1 in both inflammation and cancer progression. On the road to therapeutics? (Review)

  2020cites this paper
• Significance of taurine transporter (TauT) in homeostasis and its layers of regulation

  2020cites this paper
• Impact of the histone deacetylase inhibitor Trichostatin A on active uptake, volume-sensitive release of taurine and cell fate in human ovarian cancer cells.

  2020cites this paper
• Clinical and Genome-Wide Analysis of Serum Platinum Levels after Cisplatin-Based Chemotherapy

  2019cites this paper
• Wogonin pre-treatment attenuates cisplatin-induced nephrotoxicity in rats: Impact on PPAR-γ, inflammation, apoptosis and Wnt/β-catenin pathway.

  2019cites this paper
• Elevated SLC6A6 expression drives tumorigenesis and affects clinical outcomes in gastric cancer.

  2019cites this paper
• Protective effects of zingerone on cisplatin-induced nephrotoxicity in female rats

  2019cites this paper
• Overview of cisplatin-induced neurotoxicity and ototoxicity, and the protective agents.

  2019cites this paper
• Protective effect of avenanthramides against cisplatin induced nephrotoxicity in rats

  2019cites this paper
• New Insights in the Pathogenesis of Cisplatin-induced Nephrotoxicity

  2019cites this paper
• Genetic and Modifiable Risk Factors Contributing to Cisplatin-induced Toxicities

  2018cites this paper
• The Protective Effects of Sika Deer Antler Protein on Cisplatin-Induced Nephrotoxicity

  2017cites this paper
• Protective effect of Nigella sativa oil on cisplatin induced nephrotoxicity and oxidative damage in rat kidney.

  2017cites this paper
• Beneficial Effects of Myo-Inositol Oxygenase Deficiency in Cisplatin-Induced AKI.

  2017cites this paper
• miR-3156-3p is downregulated in HPV-positive cervical cancer and performs as a tumor-suppressive miRNA

  2017cites this paper
• Dual role of LRRC8A-containing transporters on cisplatin resistance in human ovarian cancer cells.

  2016cites this paper
• Knockout of the TauT Gene Predisposes C57BL/6 Mice to Streptozotocin-Induced Diabetic Nephropathy

  2015cites this paper
• Physiological role of taurine – from organism to organelle

  2015cites this paper
• Renal fibrogenesis and platinum compounds in a rat model: a novel Pt (II) complex vs. cisplatin.

  2015cites this paper
• In vitro characterization of a novel C,N-cyclometalated benzimidazole Ru(II) arene complex: stability, intracellular distribution and binding, effects on organic osmolyte homeostasis and induction of apoptosis.

  2015cites this paper
• Role of volume-regulated and calcium-activated anion channels in cell volume homeostasis, cancer and drug resistance

  2015cites this paper
• Ion channels and transporters in the development of drug resistance in cancer cells

  2014cites this paper
• Acquired cisplatin resistance in human ovarian A2780 cancer cells correlates with shift in taurine homeostasis and ability to volume regulate.

  2014cites this paper
• Renal Toxicology/Nephrotoxicity of Cisplatin and Other Chemotherapeutic Agents

  2014cites this paper
• Physical Biology of Cancer Acquired cisplatin resistance in human ovarian A 2780 cancer cells correlates with shift in taurine homeostasis and ability to volume regulate

  2014cites this paper
• Significant renoprotective effect of telbivudine during preemptive antiviral therapy in advanced liver cancer patients receiving cisplatin-based chemotherapy: a case–control study

  2014cites this paper
• Pathophysiology of Cisplatin-Induced Acute Kidney Injury

  2014cites this paper
• Effect of taurine on intestinal recovery following intestinal ischemia-reperfusion injury in a rat

  2014cites this paper
• Tubular p53 regulates multiple genes to mediate AKI.

  2014cites this paper
• mTOR ensures increased release and reduced uptake of the organic osmolyte taurine under hypoosmotic conditions in mouse fibroblasts.

  2014cites this paper
• Knockdown of TauT expression impairs human embryonic kidney 293 cell development.

  2013cites this paper
• Protective effect of an intrinsic antioxidant, HMH (5-hydroxy-1-methylhydantoin; NZ-419), against cellular damage of kidney tubules.

  2013cites this paper
• Upregulation of Na+,Cl--Coupled Betaine/ γ-Amino-Butyric Acid Transporter BGT1 by Tau Tubulin Kinase 2

  2013cites this paper
• Carvedilol efficiently protects kidneys without affecting the antitumor efficacy of cisplatin in mice.

  2013cites this paper
• Klotho has dual protective effects on cisplatin-induced acute kidney injury

  2013cites this paper
• Cisplatin-induced nephrotoxicity and targets of nephroprotection: an update

  2012cites this paper
• The role of taurine in renal disorders

  2012cites this paper
• Taurine and the kidneys

  2012influential citation
• Radiation protection following nuclear power accidents: a survey of putative mechanisms involved in the radioprotective actions of taurine during and after radiation exposure

  2012cites this paper
• Pathogenesis of acute kidney injury: foundation for clinical practice.

  2011cites this paper
• Taurine transporter gene expression in peripheral mononuclear blood cells of type 2 diabetic patients

  2011cites this paper
• Regulation of Taurine Transport Systems by Protein Kinase CK2 in Mammalian Cells

  2011cites this paper
• Introductory Address for John Howland Award Recipient, Russell Chesney, M.D.

  2011cites this paper
• Pinpointing Differences in Cisplatin-induced Apoptosis in Adherent and Non-adherent Cancer Cells

  2011cites this paper
• Poly(ADP-ribose) polymerase-1 is a key mediator of cisplatin-induced kidney inflammation and injury.

  2011cites this paper
• Stress-responsive gene TauT and acute kidney injury

  2010cites this paper
• Inhibitors of histone deacetylases suppress cisplatin-induced p53 activation and apoptosis in renal tubular cells.

  2010cites this paper
• Taurine and the renal system

  2010influential citation