Molecular advances in the etiology and treatment of colorectal cancer.

No abstract is available for this paper.

• Publication year

  1997

• Venue

  Surgical oncology

• Publication date

  1997-11-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/S0960-7404(97)00020-0PMID 9576630
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• 5-Azacytidine-induced undercondensations in human chromosomes

  2004cited by this paper
• Colorectal cancer screening: clinical guidelines and rationale.

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• Cancer statistics, 1997

  1997cited by this paper
• Hereditary nonpolyposis colorectal cancer: review of clinical, molecular genetics, and counseling aspects.

  1996cited by this paper
• Molecular genetic basis of colorectal cancer susceptibility

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• Suppression of Intestinal Polyposis in ApcΔ716 Knockout Mice by Inhibition of Cyclooxygenase 2 (COX-2)

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• Self-promotion? Intimate connections between APC and prostaglandin H synthase-2.

  1996cited by this paper
• Prostaglandin endoperoxide synthase: why two isoforms?

  1996cited by this paper
• Suppression of intestinal polyposis in Apc delta716 knockout mice by inhibition of cyclooxygenase 2 (COX-2).

  1996cited by this paper
• DNA mismatch binding defects, DNA damage tolerance, and mutator phenotypes in human colorectal carcinoma cell lines.

  1995cited by this paper
• The APC Protein and E-cadherin Form Similar but Independent Complexes with α-Catenin, β-Catenin, and Plakoglobin (*)

  1995cited by this paper
• The APC protein and E-cadherin form similar but independent complexes with alpha-catenin, beta-catenin, and plakoglobin.

  1995cited by this paper
• Genetics of colon cancer: impact of inheritance on colon cancer risk.

  1995cited by this paper
• Prognostic value of TP53 and K-ras-2 mutational analysis in stage III carcinoma of the colon.

  1995cited by this paper
• Loss of Apc heterozygosity and abnormal tissue building in nascent intestinal polyps in mice carrying a truncated Apc gene.

  1995cited by this paper
• The clinical and genetic manifestations of hereditary nonpolyposis colorectal carcinoma.

  1995cited by this paper
• Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2.

  1995cited by this paper
• Advances in the genetics and molecular biology of colorectal tumors.

  1994cited by this paper
• Mismatch repair and cancer

  1994cited by this paper
• Genetic steps in colorectal cancer

  1994cited by this paper
• Genetics of colorectal cancer.

  1994influential reference
• Association of p53 mutations with short survival in colorectal cancer.

  1994cited by this paper
• Wild-type but not mutant APC associates with the microtubule cytoskeleton.

  1994cited by this paper
• The APC gene product associates with microtubules in vivo and promotes their assembly in vitro.

  1994cited by this paper
• Replication errors in benign and malignant tumors from hereditary nonpolyposis colorectal cancer patients.

  1994cited by this paper
• Colon cancer connections. Cancer syndrome meets molecular biology meets histopathology.

  1994cited by this paper
• hMSH2 mutations in hereditary nonpolyposis colorectal cancer kindreds.

  1994cited by this paper
• Mutation in the DNA mismatch repair gene homologue hMLH 1 is associated with hereditary non-polyposis colon cancer

  1994cited by this paper
• Allelic loss of chromosome 18q and prognosis in colorectal cancer.

  1994cited by this paper
• Aspirin use, cancer, and polyps of the large bowel

  1993cited by this paper
• Prognostic value of p53 overexpression and c-Ki-ras gene mutations in colorectal cancer.

  1993cited by this paper
• p53 mutations increase resistance to ionizing radiation.

  1993cited by this paper
• Prevention of colorectal cancer by colonoscopic polypectomy. The National Polyp Study Workgroup.

  1993cited by this paper
• Treatment of colonic and rectal adenomas with sulindac in familial adenomatous polyposis.

  1993cited by this paper
• Hypermutability and mismatch repair deficiency in RER+ tumor cells.

  1993cited by this paper
• The genetic and molecular diagnosis of adenomatous polyposis coli.

  1993cited by this paper
• Prognostic significance of K-ras mutations in colorectal carcinoma.

  1993cited by this paper
• Clinical implications of the p53 tumor-suppressor gene.

  1993cited by this paper
• Extracolonic cancer in hereditary nonpolyposis colorectal cancer

  1993cited by this paper
• The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer.

  1993cited by this paper
• The molecular genetics of colorectal neoplasia.

  1993cited by this paper
• Association of the APC tumor suppressor protein with catenins.

  1993cited by this paper
• Genetics, natural history, tumor spectrum, and pathology of hereditary nonpolyposis colorectal cancer: an updated review.

  1993cited by this paper
• Two cases of 5q deletions in patients with familial adenomatous polyposis: possible link with Caroli's disease.

  1993cited by this paper
• Association of the APC gene product with beta-catenin.

  1993cited by this paper
• Prevention of colorectal cancer by colonoscopic polypectomy. The National Polyp Study Workgroup.

  1993cited by this paper
• Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer.

  1993cited by this paper
• Microsatellite instability is associated with tumors that characterize the hereditary non-polyposis colorectal carcinoma syndrome.

  1993cited by this paper
• A CA-repeat polymorphism close to the adenomatous polyposis coli (APC) gene offers improved diagnostic testing for familial APC.

  1993cited by this paper
• Molecular diagnosis of familial adenomatous polyposis.

  1993cited by this paper
• Association between wild type and mutant APC gene products.

  1993cited by this paper
• Cancer Risk in Relatives of Patients with Common Colorectal Cancer

  1993cited by this paper
• K-ras mutations in putative preneoplastic lesions in human colon.

  1993cited by this paper
• Alleles of the APC gene: an attenuated form of familial polyposis.

  1993cited by this paper
• Molecular genetic studies of tumor suppressor gene regions on chromosomes 13 and 17 in colorectal tumors.

  1992cited by this paper
• Families at risk of colorectal cancer: who are they?

  1992cited by this paper
• Prognostic significance of p53 overexpression in gastric and colorectal carcinoma.

  1992cited by this paper
• Correlation between the location of germ-line mutations in the APC gene and the number of colorectal polyps in familial adenomatous polyposis patients.

  1992cited by this paper
• Identification of ras oncogene mutations in the stool of patients with curable colorectal tumors.

  1992cited by this paper
• Somatic mutations of the APC gene in colorectal tumors: mutation cluster region in the APC gene.

  1992cited by this paper
• Genetic changes of both p53 alleles associated with the conversion from colorectal adenoma to early carcinoma in familial adenomatous polyposis and non-familial adenomatous polyposis patients.

  1992cited by this paper
• Phenotypic, cytogenetic, and molecular studies of three patients with constitutional deletions of chromosome 5 in the region of the gene for familial adenomatous polyposis.

  1992cited by this paper
• Screening for large bowel neoplasms individuals with a family history of colorectal cancer

  1992cited by this paper
• Survival and acquired genetic alterations in colorectal cancer.

  1992cited by this paper
• Molecular genetics of colorectal carcinoma

  1992cited by this paper
• Herditary aspects of colorectal adenomas

  1992cited by this paper
• Hereditary flat adenoma syndrome: A variant of familial adenomatous polyposis?

  1992cited by this paper
• APC mutations occur early during colorectal tumorigenesis

  1992cited by this paper
• Germ-line mutations of the APC gene in 53 familial adenomatous polyposis patients.

  1992cited by this paper
• Aspirin use and reduced risk of fatal colon cancer.

  1991cited by this paper
• Occurrence of Ki-ras and p53 mutations in primary colorectal tumors.

  1991cited by this paper
• Frequency of familial colorectal cancer

  1991cited by this paper
• The International Collaborative Group on Hereditary Non-Polyposis Colorectal Cancer (ICG-HNPCC)

  1991cited by this paper
• The p53 tumour suppressor gene

  1991cited by this paper
• p53 mutations in human cancers.

  1991cited by this paper
• Hereditary non-polyposis colorectal cancer

  1991cited by this paper
• Risk of cancer death in first‐degree relatives of patients with hereditary non‐polyposis cancer syndrome (Lynch type II): A study of 130 kindreds in the United Kingdom

  1990cited by this paper
• The tumour spectrum in hereditary non‐polyposis colorectal cancer: A study of 24 kindreds in the netherlands

  1990cited by this paper
• A genetic model for colorectal tumorigenesis.

  1990cited by this paper
• Colorectal adenomas in the Lynch syndromes. Results of a colonoscopy screening program.

  1990cited by this paper
• Human colorectal cancer: high frequency of deletions at chromosome 1p35.

  1990cited by this paper
• ras oncogenes in human cancer: a review.

  1989cited by this paper
• Characteristics of familial colon cancer in a large population data base

  1989cited by this paper
• Genetic alterations during colorectal-tumor development.

  1988cited by this paper
• Turcot's syndrome

  1988cited by this paper
• Natural history of colorectal cancer in hereditary nonpolyposis colorectal cancer (Lynch syndromes I and II)

  1988cited by this paper
• Screening for colorectal cancer in a high risk population

  1987cited by this paper
• Screening for colorectal cancer in a high-risk population. Results of a mathematical model.

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• Hereditary Gastrointestinal Polyposis Syndromes

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• Association of endocrine neoplasia with multiple polyposis of the colon

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• Biliary involvement in familial adenomatosis coli

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• Association between hepatoblastoma and polyposis coli.

  1983cited by this paper
• Penetrance and expressivity of the gene responsible for the Gardner syndrome

  1977cited by this paper
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