Nonylphenol Alters Connexin 43 Levels and Connexin 43 Phosphorylation Via an Inhibition of the p38-Mitogen-Activated Protein Kinase Pathway1

No abstract is available for this paper.

• Publication year

  2005

• Venue

  Biology of Reproduction

• Publication date

  2005-05-01

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1095/biolreprod.104.038596PMID 15647452
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Seeds of concern

  2004cited by this paper
• A proposed role for ZO-1 in targeting connexin 43 gap junctions to the endocytic pathway.

  2004cited by this paper
• Prevention of organochlorine-induced inhibition of gap junctional communication by chaetoglobosin K in astrocytes

  2004cited by this paper
• Enhancing effect of the endocrine disruptor para-nonylphenol on the generation of reactive oxygen species in human blood neutrophils.

  2004cited by this paper
• How strong is the evidence of a link between environmental chemicals and adverse effects on human reproductive health?

  2004cited by this paper
• The toxic effects of nonylphenol on the reproductive system of male rats.

  2004cited by this paper
• Consumption of xenoestrogen-contaminated fish during lactation alters adult male reproductive function.

  2004cited by this paper
• Consequences of xenoestrogen exposure on male reproductive function in spottail shiners (Notropis hudsonius).

  2004cited by this paper
• Assessment of pubertal development in juvenile male rats after sub-acute exposure to bisphenol A and nonylphenol.

  2003cited by this paper
• Aberrant Connexin 43 endocytosis by the carcinogen lindane involves activation of the ERK/mitogen-activated protein kinase pathway.

  2003cited by this paper
• Transforming Growth Factor β3 Regulates the Dynamics of Sertoli Cell Tight Junctions Via the p38 Mitogen-Activated Protein Kinase Pathway1

  2003cited by this paper
• Restoration of gap junctional intercellular communication by dibutyryl-cAMP in renal epithelial cells treated with renal carcinogen.

  2003cited by this paper
• Environmental pollutants and breast cancer.

  2003cited by this paper
• TGF-beta3 regulates the blood-testis barrier dynamics via the p38 mitogen activated protein (MAP) kinase pathway: an in vivo study.

  2003cited by this paper
• 17beta-Estradiol and environmental estrogens significantly affect mammalian sperm function.

  2003cited by this paper
• Occurrence of alkylphenol polyethoxylates in the St. Lawrence River and their bioconcentration by mussels (Elliptio complanata).

  2003cited by this paper
• Decreased gap junctional intercellular communication in hexachlorobenzene-induced gender-specific hepatic tumor formation in the rat.

  2002cited by this paper
• Environmental Health Perspectives

  2002cited by this paper
• Estrogens and environmental estrogens.

  2002cited by this paper
• Effect of nonylphenol on the antioxidant system in epididymal sperm of rats

  2002cited by this paper
• In utero reproductive study in rats exposed to nonylphenol.

  2001cited by this paper
• Failure of Spermatogenesis in Mice Lacking Connexin431

  2001cited by this paper
• Disruption of gap junctional intercellular communication by lindane is associated with aberrant localization of connexin43 and zonula occludens-1 in 42GPA9 Sertoli cells.

  2001cited by this paper
• Developmental regulation of connexin 43 expression in fetal mouse testicular cells

  2001cited by this paper
• Hormones and testis development and the possible adverse effects of environmental chemicals.

  2001cited by this paper
• Unique and shared functions of different connexins in mice.

  2000cited by this paper
• Disruption of the reproductive system and reproductive performance by administration of nonyiphenol to newborn rats

  2000cited by this paper
• Connexin43 Gene Expression and Regulation in the Rodent Seminiferous Epithelium

  2000cited by this paper
• Analysis of connexin phosphorylation sites.

  2000cited by this paper
• Cadmium decreases gap junctional intercellular communication in mouse liver.

  2000cited by this paper
• Connexin Gene Expression in Seminiferous Tubules of the Sprague-Dawley Rat1

  2000cited by this paper
• Phosphorylation of Connexin43 on Serine368 by Protein Kinase C Regulates Gap Junctional Communication

  2000cited by this paper
• Estrogenic activity of octylphenol, nonylphenol, bisphenol A and methoxychlor in rats.

  2000cited by this paper
• II. The effect of p-nonylphenol on the fertility potential of male rats after gestational, lactational and direct exposure

  1999cited by this paper
• Cellular immunolocalization of occludin during embryonic and postnatal development of the mouse testis and epididymis.

  1999cited by this paper
• I. The effect of p‐nonylphenol, an environmental toxicant with oestrogenic properties, on fertility potential in adult male rats

  1999cited by this paper
• Defects in the germ line and gonads of mice lacking connexin43.

  1999cited by this paper
• II. The effect of p‐nonylphenol on the fertility potential of male rats after gestational, lactational and direct exposure

  1999cited by this paper
• Permanent Effects of Neonatal Estrogen Exposure in Rats on Reproductive Hormone Levels, Sertoli Cell Number, and the Efficiency of Spermatogenesis in Adulthood1.

  1999cited by this paper
• Modified expression of testicular gap-junction connexin 43 during normal spermatogenic cycle and in altered spermatogenesis

  1999cited by this paper
• Toxic effects of octylphenol on cultured rat spermatogenic cells and Sertoli cells.

  1999cited by this paper
• Inhibition of hCG-stimulated steroidogenesis in cultured mouse Leydig tumor cells by bisphenol A and octylphenols.

  1999cited by this paper
• Phosphorylation of connexin43 and the regulation of neonatal rat cardiac myocyte gap junctions.

  1997cited by this paper
• Tyrosine Phosphorylation of Connexin 43 by v-Src Is Mediated by SH2 and SH3 Domain Interactions*

  1997cited by this paper
• Biochemical and molecular changes at the cellular level in response to exposure to environmental estrogen-like chemicals.

  1997cited by this paper
• Characterization of the Mitogen-activated Protein Kinase Phosphorylation Sites on the Connexin-43 Gap Junction Protein (*)

  1996cited by this paper
• Assessing environmental chemicals for estrogenicity using a combination of in vitro and in vivo assays.

  1996cited by this paper
• Male reproductive health and environmental xenoestrogens.

  1996cited by this paper
• Inhibition of gap junctional intercellular communication in heptachlor- and heptachlor epoxide-treated normal human breast epithelial cells

  1996cited by this paper
• Localization and function of the connexin 43 gap‐junction protein in normal and various oncogene‐expressing rat liver epithelial cells

  1996cited by this paper
• Connections with connexins: the molecular basis of direct intercellular signaling.

  1996cited by this paper
• Regulated assembly of connexin33 and connexin43 into rat Sertoli cell gap junctions.

  1996cited by this paper
• Gestational and lactational exposure of rats to xenoestrogens results in reduced testicular size and sperm production.

  1995cited by this paper
• Inhibition of rat liver gap junction intercellular communication by tumor-promoting agents in vivo. Association with aberrant localization of connexin proteins.

  1995cited by this paper
• Changes in gap‐junction permeability, phosphorylation, and number mediated by phorbol ester and non‐phorbol‐ester tumor promoters in rat liver epithelial cells

  1994cited by this paper
• Two inhibitors of gap junctional intercellular communication, TPA and endosulfan: different effects on phosphorylation of connexin 43 in the rat liver epithelial cell line, IAR 20.

  1994cited by this paper
• Biodegradation of 4-nonylphenol in seawater and sediment.

  1993cited by this paper
• Declining sperm counts in men--is there an endocrine cause?

  1993cited by this paper
• Evidence for decreasing quality of semen during past 50 years.

  1992cited by this paper
• Cell-, age- and stage-dependent distribution of connexin43 gap junctions in testes.

  1992cited by this paper
• Connexin43 in MDCK cells: regulation by a tumor-promoting phorbol ester and Ca2+.

  1992cited by this paper
• Tissue-specific distribution of differentially phosphorylated forms of Cx43

  1991cited by this paper
• Turnover and phosphorylation dynamics of connexin43 gap junction protein in cultured cardiac myocytes.

  1991cited by this paper
• p-Nonyl-phenol: an estrogenic xenobiotic released from "modified" polystyrene.

  1991cited by this paper
• The tumor promoter 12-O-tetradecanoylphorbol-13-acetate and the ras oncogene modulate expression and phosphorylation of gap junction proteins

  1991cited by this paper
• Expression of the gap junction protein connexin43 in embryonic chick lens: Molecular cloning, ultrastructural localization, and post-translational phosphorylation

  1990cited by this paper
• Phosphorylation of connexin43 gap junction protein in uninfected and Rous sarcoma virus-transformed mammalian fibroblasts

  1990cited by this paper
• The actions of calcitonin on the TM3 Leydig cell line and on rat Leydig cell-enriched cultures.

  1989cited by this paper
• Estrogen and androgen receptors in Sertoli, Leydig, myoid, and epithelial cells: effects of time in culture and cell density.

  1984cited by this paper
• 4-Nonylphenol in sewage sludge: accumulation of toxic metabolites from nonionic surfactants.

  1984cited by this paper
• Gap junctions between Sertoli and germ cells of rat seminiferous tubules.

  1979cited by this paper
• The Sertoli cell occluding junctions and gap junctions in mature and developing mammalian testis.

  1976cited by this paper

• Endocrine Disrupting Agents: Toxicological Aspects on Male Reproduction

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  2018cites this paper
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  2018cites this paper
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  2017cites this paper
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  2016cites this paper
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  2016cites this paper
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  2016cites this paper
• Protection of erythropoietin against ischemic neurovascular unit injuries through the effects of connexin43.

  2015cites this paper
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  2015influential citation
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• Sertoli cells are the target of environmental toxicants in the testis – a mechanistic and therapeutic insight

  2015cites this paper
• Effects of 4-nonylphenol isomers on cell receptors and mitogen-activated protein kinase pathway in mouse Sertoli TM4 cells.

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  2013cites this paper
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  2012cites this paper
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  2011cites this paper
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  2007cites this paper
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