In this review, we discuss violacein and prodigiosin, two chromogenic bacterial secondary metabolites that have diverse biological activities. Although both compounds were “discovered” more than seven decades ago, interest into their biological applications has grown in the last two decades, particularly driven by their antimicrobial and anticancer properties. These topics will be discussed in the first half of this review. The latter half delves into the current efforts of groups to produce these two compounds. This includes in both their native bacterial hosts and heterogeneously in other bacterial hosts, including discussing some of the caveats related to the yields reported in the literature, and some of the synthetic biology techniques employed in this pursuit.
Biotechnological Activities and Applications of Bacterial Pigments Violacein and Prodigiosin
S. Choi,S. Lim,Kyoung-Hye Yoon,J. I. Lee,R. Mitchell
Published 2021 in Journal of Biological Engineering
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- Publication year
2021
- Venue
Journal of Biological Engineering
- Publication date
2021-03-11
- Fields of study
Biology, Medicine, Chemistry, Environmental Science
- Identifiers
- External record
- Source metadata
Semantic Scholar, PubMed
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