Reactive oxygen species from mitochondria induce cyclooxygenase-2 gene expression in human mesangial cells: potential role in diabetic nephropathy.

No abstract is available for this paper.

• Publication year

  2003

• Venue

  Diabetes

• Publication date

  2003-10-01

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.2337/DIABETES.52.10.2570PMID 14514642
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Technical Advance A New Method for Large Scale Isolation of Kidney Glomeruli from Mice

  2002cited by this paper
• Immunohistochemical and functional correlations of renal cyclooxygenase-2 in experimental diabetes.

  2001influential reference
• Human thymus contains IFN-alpha-producing CD11c(-), myeloid CD11c(+), and mature interdigitating dendritic cells.

  2001cited by this paper
• Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage

  2000influential reference
• Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation.

  2000cited by this paper
• NF-kappaB and AP-1 are required for cyclo-oxygenase 2 gene expression in amnion epithelial cell line (WISH).

  2000cited by this paper
• Extension of life-span with superoxide dismutase/catalase mimetics.

  2000cited by this paper
• Effects of ramipril on cardiovascular and microvascular outcomes in people with diabetes mellitus: results of the HOPE study and MICRO-HOPE substudy. Heart Outcomes Prevention Evaluation Study Investigators.

  2000cited by this paper
• Effects of ramipril on cardiovascular and microvascular outcomes in people with diabetes mellitus: results of the HOPE study and MICRO-HOPE substudy. Heart Outcomes Prevention Evaluation Study Investigators.

  2000cited by this paper
• Redox-dependent trafficking of 2,3,4,5, 6-pentafluorodihydrotetramethylrosamine, a novel fluorogenic indicator of cellular oxidative activity.

  2000cited by this paper
• Quantifying cellular oxidative stress by dichlorofluorescein assay using microplate reader.

  1999cited by this paper
• High-dose vitamin E supplementation normalizes retinal blood flow and creatinine clearance in patients with type 1 diabetes.

  1999cited by this paper
• A nonpeptidyl mimic of superoxide dismutase with therapeutic activity in rats.

  1999cited by this paper
• Sequential effects of high glucose on mesangial cell transforming growth factor-beta 1 and fibronectin synthesis.

  1998cited by this paper
• Cyclooxygenase-2 participates in tubular flow-dependent afferent arteriolar tone: interaction with neuronal NOS.

  1998cited by this paper
• Budesonide epimer R or dexamethasone selectively inhibit platelet-activating factor-induced or interleukin 1beta-induced DNA binding activity of cis-acting transcription factors and cyclooxygenase-2 gene expression in human epidermal keratinocytes.

  1998cited by this paper
• Hypoxia Induces Cyclooxygenase-2 via the NF-κB p65 Transcription Factor in Human Vascular Endothelial Cells*

  1997cited by this paper
• Cyclooxygenase 2 induction: molecular mechanism and pathophysiologic roles.

  1996influential reference
• Nitric oxide amplifies interleukin 1-induced cyclooxygenase-2 expression in rat mesangial cells.

  1996cited by this paper
• Oxidative Stress and Diabetic Vascular Complications

  1996cited by this paper
• Transcriptional Roles of Nuclear Factor B and Nuclear Factor-Interleukin-6 in the Tumor Necrosis Factor -Dependent Induction of Cyclooxygenase-2 in MC3T3-E1 Cells (*)

  1995cited by this paper
• Transcriptional Regulation of Human Prostaglandin-endoperoxide Synthase-2 Gene by Lipopolysaccharide and Phorbol Ester in Vascular Endothelial Cells

  1995cited by this paper
• Transcriptional roles of nuclear factor kappa B and nuclear factor-interleukin-6 in the tumor necrosis factor alpha-dependent induction of cyclooxygenase-2 in MC3T3-E1 cells.

  1995cited by this paper
• Characterization of the genomic structure, chromosomal location and promoter of human prostaglandin H synthase-2 gene.

  1994cited by this paper
• Glomerular prostaglandins modulate vascular reactivity of the downstream efferent arterioles.

  1994cited by this paper
• Cyclooxygenase-2 is associated with the macula densa of rat kidney and increases with salt restriction.

  1994cited by this paper
• Purification and characterization of a novel, distinct isoform of prostaglandin endoperoxide synthase induced by human chorionic gonadotropin in granulosa cells of rat preovulatory follicles.

  1992influential reference
• Role of Oxidative Stress in Development of Complications in Diabetes

  1991cited by this paper
• Sequential alterations in glomerular prostaglandin and thromboxane synthesis in diabetic rats: relationship to the hyperfiltration of early diabetes.

  1987cited by this paper
• Increased prostaglandin production by glomeruli isolated from rats with streptozotocin-induced diabetes mellitus.

  1985cited by this paper
• Glomerular hemodynamics in experimental diabetes mellitus.

  1981cited by this paper
• Abnormally Increased Glomerular Filtration Rate in Short-term Insulin-treated Diabetic Subjects

  1967cited by this paper

• Transcriptomic Analysis Reveals Novel Mechanisms Underlying Neutrophil Activation Induced by High Salt

  2026cites this paper
• Immune-mediated renal injury in diabetic kidney disease: from mechanisms to therapy

  2025cites this paper
• -Association of CYP8B1 rs3732860 Polymorphism and Gene Expression with Oxidative Stress and biochemical Markers in Type 2 Diabetes Mellitus

  2025cites this paper
• Diabetic kidney disease: m6A modification as a marker of disease progression and subtype classification

  2025cites this paper
• Agmatine ameliorates diabetes type 2-induced nephropathy in rats

  2024cites this paper
• Endothelial NOX5 Obliterates the Reno-Protective Effect of Nox4 Deletion by Promoting Renal Fibrosis via Activation of EMT and ROS-Sensitive Pathways in Diabetes

  2024cites this paper
• Hexokinase-linked glycolytic overload and unscheduled glycolysis in hyperglycemia-induced pathogenesis of insulin resistance, beta-cell glucotoxicity, and diabetic vascular complications

  2024cites this paper
• The potential protective effect of propolis on diabetic nephropathy induced by streptozotocin in adult albino rats

  2024cites this paper
• Spilanthes filicaulis (Schumach. & Thonn.) C.D. Adams leaves protects against streptozotocin-induced diabetic nephropathy

  2024cites this paper
• Assessment of the effect of sodium tetraborate on oxidative stress, inflammation, and apoptosis in lead-induced nephrotoxicity

  2024cites this paper
• The roles of dietary polyphenols at crosstalk between type 2 diabetes and Alzheimer's disease in ameliorating oxidative stress and mitochondrial dysfunction via PI3K/Akt signaling pathways.

  2024cites this paper
• Recent Pharmacological Options in Type 2 Diabetes and Synergic Mechanism in Cardiovascular Disease

  2023cites this paper
• Quercetin Mitigates Diabetic Nephropathy in Rats via Keap1/Nrf2/HO-1 Signaling Pathway

  2023cites this paper
• Postictal hypoxia involves reactive oxygen species and is ameliorated by chronic mitochondrial uncoupling.

  2023cites this paper
• Response of a Human Lens Epithelial Cell Line to Hyperglycemic and Oxidative Stress: The Role of Aldose Reductase

  2023cites this paper
• Network-based identification and prioritization of key transcriptional factors of diabetic kidney disease

  2023cites this paper
• Neuroprotective Effects of a Hydrogen Sulfide Donor in Streptozotocin-Induced Diabetic Rats

  2023cites this paper
• Sex-Specific Variations in the mRNA Levels of Candidate Genes in Peripheral Blood Mononuclear Cells from Patients with Diabetes: A Multistep Study

  2023cites this paper
• Biomarkers and signaling pathways of diabetic nephropathy and peripheral neuropathy: possible therapeutic intervention of rutin and quercetin

  2023cites this paper
• Staphylococcus epidermidis WF2R11 Suppresses PM2.5-Mediated Activation of the Aryl Hydrocarbon Receptor in HaCaT Keratinocytes

  2022cites this paper
• Integration of various protein similarities using random forest technique to infer augmented drug-protein matrix for enhancing drug-disease association prediction

  2022cites this paper
• Hexokinase-2-Linked Glycolytic Overload and Unscheduled Glycolysis—Driver of Insulin Resistance and Development of Vascular Complications of Diabetes

  2022cites this paper
• Chemical inhibition of mitochondrial fission improves insulin signaling and subdues hyperglycemia induced stress in placental trophoblast cells

  2022cites this paper
• Use of Ferulic Acid in the Management of Diabetes Mellitus and Its Complications

  2022cites this paper
• Role of aquaporin 9 in hyperglycaemia-induced testicular leydig cell apoptosis

  2022cites this paper
• Mitophagy and mitochondrial dynamics in type 2 diabetes mellitus treatment

  2022cites this paper
• IL-23 production in human macrophages is regulated negatively by tumor necrosis factor α-induced protein 3 and positively by specificity protein 1 after stimulation of the toll-like receptor 7/8 signaling pathway

  2022cites this paper
• Taurine improves health of juvenile rice field eel (Monopterus albus) fed with oxidized fish oil: Involvement of lipid metabolism, antioxidant capacity, inflammatory response

  2022cites this paper
• Molecular Mechanisms of Diabetic Kidney Disease

  2022cites this paper
• Nutritional intervention for diabetes mellitus with Alzheimer's disease

  2022cites this paper
• Saffron as a promising therapy for diabetes and Alzheimer's disease: mechanistic insights

  2022cites this paper
• Transcript Expression Profiles and MicroRNA Regulation Indicate an Upregulation of Processes Linked to Oxidative Stress, DNA Repair, Cell Death, and Inflammation in Type 1 Diabetes Mellitus Patients

  2022cites this paper
• Antioxidant Potential of Non-Extractable Fractions of Dried Persimmon (Diospyros kaki Thunb.) in Streptozotocin-Induced Diabetic Rats

  2022cites this paper
• Genetic variations of tumor necrosis factor-α and prostaglandin-endoperoxide synthase 2 genes among Egyptian patients with type 2 diabetes mellitus and diabetic nephropathy

  2022cites this paper
• Inflammation and Diabetic Kidney Disease: New Perspectives

  2022cites this paper
• Research Progress on the Positive and Negative Regulatory Effects of Rhein on the Kidney: A Review of Its Molecular Targets

  2022cites this paper
• International Journal of Scientific Research in Science and Technology

  2021cites this paper
• PP2 Ameliorates Renal Fibrosis by Regulating the NF-κB/COX-2 and PPARγ/UCP2 Pathway in Diabetic Mice

  2021cites this paper
• Effects of the Type and Volume of Physical Activity on Leukocyte Telomere Length in Middle-Aged Men

  2021cites this paper
• Diabetic Nephropathy: Challenges in Pathogenesis, Diagnosis, and Treatment

  2021cites this paper
• Chronic Diclofenac Exposure Increases Mitochondrial Oxidative Stress, Inflammatory Mediators, and Cardiac Dysfunction

  2021cites this paper
• Effect of Vanillic Acid in Streptozotocin Induced Diabetic Neuropathy

  2021cites this paper
• Therapeutic Potential of Astaxanthin in Diabetic Kidney Disease.

  2021cites this paper
• Mitochondrial Dysfunction and Mitophagy Closely Cooperate in Neurological Deficits Associated with Alzheimer’s Disease and Type 2 Diabetes

  2021influential citation
• Roles of mTOR in Diabetic Kidney Disease

  2021cites this paper
• Protection of 6-OHDA neurotoxicity by PGF2α through FP-ERK-Nrf2 signaling in SH-SY5Y cells.

  2021cites this paper
• Arbuscular Mycorrhizal Fungi : Diversity and Its Impact with Abiotic Factors in Phoenix dactylifera L. of Kachchh Region, Gujarat, India

  2021cites this paper
• Reactive Oxygen Species: Not Omnipresent but Important in Many Locations

  2021cites this paper
• Spatially Organized Functional Bioreactors in Nanoscale Mesoporous MOFs for Cascade Scavenging of Intracellular ROS

  2021cites this paper
• Functions of ROS in Macrophages and Antimicrobial Immunity

  2021cites this paper
• The emerging role of COX-2, 15-LOX, and PPARγ in metabolic diseases and cancer: An introduction to novel multi-target directed ligands (MTDLs).

  2020cites this paper
• Unresponsiveness to inhaled antigen is governed by conventional dendritic cells and overridden during infection by monocytes

  2020cites this paper
• Mechanisms of action of metformin in type 2 diabetes: Effects on mitochondria and leukocyte-endothelium interactions

  2020influential citation
• The effect of tropisetron on oxidative stress, SIRT1, FOXO3a, and claudin-1 in the renal tissue of STZ-induced diabetic rats

  2020cites this paper
• CROSS LINKAGE BETWEEN OXIDATIVE STRESSES IN DIABETIC NEPHROPATHY: AN UPDATED REVIEW

  2020cites this paper
• Sinapic Acid Ameliorates the Progression of Streptozotocin (STZ)-Induced Diabetic Nephropathy in Rats via NRF2/HO-1 Mediated Pathways

  2020cites this paper
• MicroRNA-140-5p ameliorates the high glucose-induced apoptosis and inflammation through suppressing TLR4/NF-κB signaling pathway in human renal tubular epithelial cells

  2020cites this paper
• Levosimendan Prevents Memory Impairment Induced by Diabetes in Rats: Role of Oxidative Stress.

  2020cites this paper
• Low-dose lixisenatide protects against early-onset nephropathy induced in diabetic rats.

  2020cites this paper
• Effect of Solanum torvum Swartz on diabetic neuropathy in alloxan-induced diabetic rats

  2020cites this paper
• OxHDL controls LOX-1 expression and plasma membrane localization through a mechanism dependent on NOX/ROS/NF-κB pathway on endothelial cells

  2019cites this paper
• Hexokinase-2 Glycolytic Overload in Diabetes and Ischemia-Reperfusion Injury.

  2019cites this paper
• Type 2 diabetes mellitus, oxidative stress and inflammation: examining the links.

  2019cites this paper
• The Dualistic Effect of COX-2-Mediated Signaling in Obesity and Insulin Resistance

  2019cites this paper
• Endothelium structure and function in kidney health and disease

  2019cites this paper
• Lysophosphatidylcholine-induced mitochondrial fission contributes to collagen production in human cardiac fibroblasts[S]

  2019cites this paper
• Understanding Biochemical and Molecular Mechanism of Complications of Glycation and Its Management by Herbal Medicine

  2019cites this paper
• Manganese Oxide Nanozymes Ameliorate Mechanical Allodynia in a Rat Model of Partial Sciatic Nerve-Transection Induced Neuropathic Pain

  2019cites this paper
• Protective Role of Peroxiredoxins against Reactive Oxygen Species in Neonatal Rat Testicular Gonocytes

  2019cites this paper
• Endothelial Toxicity of High Glucose and its by-Products in Diabetic Kidney Disease

  2019cites this paper
• Recent advances in the pathogenesis of microvascular complications in diabetes

  2019cites this paper
• Die funktionelle Rolle des tubulären Renin-Systems

  2019cites this paper
• DNA Methylome and Transcriptome Alterations in High Glucose-Induced Diabetic Nephropathy Cellular Model and Identification of Novel Targets for Treatment by Tanshinone IIA.

  2019cites this paper
• Allicin modulates diclofenac sodium induced hepatonephro toxicity in rats via reducing oxidative stress and caspase 3 protein expression.

  2019cites this paper
• Renoprotective Effect of Danhong Injection on Streptozotocin-Induced Diabetic Rats through a Peroxisome Proliferator-Activated Receptor γ Mediated Pathway

  2018cites this paper
• Kobe University Repository : Kernel タイトル Tit le Methylglyoxal Induces Prostaglandin E 2 Product ion in Rat Mesangial Cells

  2018cites this paper
• SET8 is involved in the regulation of hyperglycemic memory in human umbilical endothelial cells

  2018cites this paper
• Effect of Bangle (Zingiber purpureum) extract and low-intensity exercise on mTOR phosphorylation and autophagy flux in skeletal muscles of rats on a high-fat diet

  2018cites this paper
• A potential strategy for treating atherosclerosis: improving endothelial function via AMP-activated protein kinase

  2018cites this paper
• The prophylactic and therapeutic effects of Momordica charantia methanol extract through controlling different hallmarks of the hepatocarcinogenesis.

  2018cites this paper
• Effects of Physical Activity, Exercise Training and Physical Fitness on Telomere Length as Biomarker of Cell Aging

  2018cites this paper
• Glucose Transporters in Diabetic Kidney Disease—Friends or Foes?

  2018cites this paper
• Protective effects of human induced pluripotent stem cell-derived exosomes on high glucose-induced injury in human endothelial cells

  2018cites this paper
• Diabetic nephropathy: Is there a role for oxidative stress?

  2018cites this paper
• A Review on Diabetic Neuropathy

  2018cites this paper
• Effects of Moringa Oleifera Aqueous Leaf Extract on Submandibular Salivary Glands of Diabetic Albino Rats

  2018cites this paper
• Astragaloside IV protects rat retinal capillary endothelial cells against high glucose-induced oxidative injury

  2017cites this paper
• Activation of Nrf2 signaling by natural products-can it alleviate diabetes?

  2017cites this paper
• Mitochondrial dynamics in type 2 diabetes: Pathophysiological implications

  2017cites this paper
• Papel de las especies reactivas de oxígeno en la función endotelial renal y en la disfunción endotelial asociada a la obesidad

  2017cites this paper
• Perturbed Brain Energy Metabolism in Alzheimer’s Disease and Diabetes

  2017cites this paper
• Recent Progress in Therapeutics for Inflammation-Associated Preterm Birth

  2017cites this paper
• Diabetes-Induced Reactive Oxygen Species: Mechanism of Their Generation and Role in Renal Injury

  2017cites this paper
• Optimized multiplex immunofluorescence single-cell analysis reveals tuft cell heterogeneity.

  2017cites this paper
• The Novel Compound Sul-121 Preserves Endothelial Function and Inhibits Progression of Kidney Damage in Type 2 Diabetes Mellitus in Mice

  2017cites this paper
• Palmitate induces mitochondrial superoxide generation and activates AMPK in podocytes

  2017cites this paper
• Higher mitochondrial potential and elevated mitochondrial respiration are associated with excessive activation of blood platelets in diabetic rats.

  2016cites this paper
• Momordica charantia polysaccharides mitigate the progression of STZ induced diabetic nephropathy in rats.

  2016cites this paper
• Estimation of Levels of Non-Enzymatic Antioxidants In Saliva of Chronic Periodontitis Patients with Type 2 Diabetes Mellitus Before And After Phase 1 Periodontal Therapy- A Prospective Follow Up Study

  2016cites this paper
• Aryl Hydrocarbon Receptor Deficiency Attenuates Oxidative Stress-Related Mesangial Cell Activation and Macrophage Infiltration and Extracellular Matrix Accumulation in Diabetic Nephropathy

  2016influential citation