Nasal administration of opioids for pain management in adults

No abstract is available for this paper.

• Publication year

  2002

• Venue

  Acta Anaesthesiologica Scandinavica

• Publication date

  2002-08-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1034/j.1399-6576.2002.460702.xPMID 12139528
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Peptide and Protein Drug Delivery

  2024cited by this paper
• Drug Metabolism in the Nasal Mucosa

  2004cited by this paper
• Otolaryngology- Head and Neck Surgery

  2004cited by this paper
• Improving the quality of reporting in randomised controlled trials.

  2004cited by this paper
• The absolute bioavailability of transnasal butorphanol in patients experiencing rhinitis

  2004cited by this paper
• Glutathione transferases in human nasal mucosa

  2004cited by this paper
• Multicentre randomised controlled trial of nasal diamorphine for analgesia in children and teenagers with clinical fractures

  2001cited by this paper
• Complaints related to respiratory events in anaesthesia and intensive care medicine from 1994 to 1998 in Denmark

  2001cited by this paper
• An assessment of the safety, efficacy, and acceptability of intranasal fentanyl citrate in the management of cancer-related breakthrough pain: a pilot study.

  2000cited by this paper
• Patient-controlled intranasal diamorphine for postoperative pain: an acceptability study.

  2000cited by this paper
• An open-label evaluation of the efficacy and safety of Stadol NS with ibuprofen in the treatment of pain after removal of impacted wisdom teeth.

  2000cited by this paper
• Patient-controlled intranasal analgesia: effective alternative to intravenous PCA for postoperative pain relief

  2000influential reference
• Effectiveness of Stadol NS (butorphanol tartrate) with ibuprofen in the treatment of pain after laser-assisted uvulopalatopharyngoplasty.

  2000cited by this paper
• Head and Neck Surgery—Otolaryngology

  2000cited by this paper
• Single‐ and Repeated‐dose Local Toxicity in the Nasal Cavity of Rabbits after Intranasal Administration of Different Glycols for Formulations Containing Benzodiazepines

  1999cited by this paper
• Immunohistochemical study of cytochrome P450 2C and 3A in human non-neoplastic and neoplastic tissues

  1999cited by this paper
• MECHANISMS AND MANAGEMENT

  1998cited by this paper
• Xenobiotic-metabolizing enzymes in pig nasal and hepatic tissues.

  1998cited by this paper
• Intranasal drug delivery.

  1998cited by this paper
• Rhinitis: Mechanisms and Management

  1998cited by this paper
• Transnasal Butorphanol: Pain Relief in the Head and Neck Patient

  1997cited by this paper
• Nasal cytochrome P450 2A: identification, regional localization, and metabolic activity toward hexamethylphosphoramide, a known nasal carcinogen.

  1997cited by this paper
• The Pharmacokinetics of Butorphanol and its Metabolites at Steady State Following Nasal Administration in Humans

  1997cited by this paper
• Pharmacokinetic Interaction Between Butorphanol Nasal Spray and Oral Metoclopramide in Healthy Women

  1997cited by this paper
• The princes and princesses of possibilities.

  1997cited by this paper
• Preliminary Clinical use of a Patient-Controlled Intranasal Analgesia (PCINA) Device

  1997cited by this paper
• A prospective comparison of transnasal butorphanol and acetaminophen with codeine for the relief of acute musculoskeletal pain.

  1997cited by this paper
• Patient-controlled intranasal analgesia.

  1997cited by this paper
• Direct drug transport from the nasal cavity to the cerebrospinal fluid. A new strategy for drug delivery to the brain

  1997cited by this paper
• Selective delivery of insulin into the brain: Intraolfactory absorption

  1997cited by this paper
• Solubilization of various benzodiazepines for intranasal administration, a pilot study.

  1997cited by this paper
• Erratum to “Selective delivery of insulin into the brain: Intraolfactory absorption” [Int. J. Pharm. 140 (1996) 77]

  1997cited by this paper
• Pharmacokinetic and Pharmacodynamic Response after Intranasal Administration of Diazepam to Rabbits

  1997cited by this paper
• Pharmacokinetic comparison of intravenous and intranasal administration of oxycodone

  1997influential reference
• Olfactory Absorption of Insulin to the Brain

  1997cited by this paper
• Patient-controlled intranasal analgesia (PCINA) for the management of postoperative pain: a pilot study.

  1996cited by this paper
• Lack of pharmacokinetic interaction between butorphanol nasal spray and cimetidine.

  1996cited by this paper
• Pharmacokinetics of butorphanol nasal spray in patients with renal impairment.

  1996cited by this paper
• Patient-Controlled Intranasal Analgesia: A Method for Noninvasive Postoperative Pain Management

  1996influential reference
• Self-administered intranasal meperidine for postoperative pain management.

  1996influential reference
• The CONSORT Statement

  1996cited by this paper
• Improving the quality of reporting of randomized controlled trials. The CONSORT statement.

  1996cited by this paper
• The absolute bioavailability and pharmacokinetics of butorphanol nasal spray in patients with hepatic impairment

  1996cited by this paper
• Transnasal Butorphanol in the Treatment of Acute Migraine

  1995cited by this paper
• Transnasal butorphanol. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in acute pain management.

  1995influential reference
• Pharmacokinetics of intranasal alfentanil.

  1995cited by this paper
• The nasal route of cerebrospinal fluid drainage in man. A light–microscope study

  1994cited by this paper
• Peptide and Protein Drugs

  1994cited by this paper
• Effectiveness of transnasal butorphanol for the treatment of musculoskeletal pain.

  1994cited by this paper
• The effects of age and sex on the systemic

  1994cited by this paper
• CSF drains directly from the subarachnoid space into nasal lymphatics in the rat. Anatomy, histology and immunological significance

  1993cited by this paper
• Intranasal fentanyl titration for postoperative pain management in an unselected population

  1993influential reference
• Biopharmaceutical evaluation of transnasal, sublingual, and buccal disk dosage forms of butorphanol

  1993cited by this paper
• [Intranasal fentanyl for breakthrough cancer pain. A pilot study.].

  1993cited by this paper
• Multiple‐dose phase I study of transnasal butorphanol

  1993cited by this paper
• Acetone-dependent regulation of cytochromes P4502E1 and P4502B1 in rat nasal mucosa.

  1993cited by this paper
• [Pharmacokinetics of intranasal Fentanyl.].

  1993cited by this paper
• Glutathione transferase isoenzymes in olfactory and respiratory epithelium of cattle.

  1993cited by this paper
• Intranasal Meperidine Titration for Postoperative Pain Relief

  1993influential reference
• Transnasal butorphanol tartrate for pain control following ambulatory surgery

  1992cited by this paper
• Drug-metabolizing enzymes in respiratory nasal mucosa and liver of cynomolgus monkey.

  1992cited by this paper
• Postoperative pain management by intranasal demand-adapted fentanyl titration.

  1992cited by this paper
• Transnasal butorphanol and intramuscular meperidine in the treatment of postoperative pain

  1992cited by this paper
• Transnasal butorphanol: a new method for pain relief in post‐cesarean section pain

  1991cited by this paper
• Postoperative patient‐controlled analgesia with sufentanil: analgesic efficacy and minimum effective concentrations

  1991cited by this paper
• Xenobiotic-metabolizing enzymes in human respiratory nasal mucosa.

  1991influential reference
• Nose-blowing and CSF rhinorrhoea.

  1991cited by this paper
• Postoperative patient-controlled analgesia with alfentanil: analgesic efficacy and minimum effective concentrations.

  1990cited by this paper
• Evaluation of alternate routes for delivery of leuprolide

  1990cited by this paper
• Metabolism of diethylnitrosamine by microsomes of human respiratory nasal mucosa and liver.

  1989cited by this paper
• Intranasal Drug Delivery

  1989cited by this paper
• The systemic availability of buprenorphine administered by nasal spray

  1989cited by this paper
• Nasal absorption and metabolism of progesterone and 17 beta-estradiol in the rat.

  1989cited by this paper
• Comparison of intravenous and intranasal sufentanil absorption and sedation

  1989cited by this paper
• Mechanism of nasal absorption of drugs.

  1989cited by this paper
• Mechanism of nasal absorption of drugs.

  1989cited by this paper
• Biotransformation enzymes in nasal mucosa and liver of Sprague-Dawley rats.

  1988influential reference
• Balanced anesthesia and patient-controlled postoperative analgesia with fentanyl: minimum effective concentrations, accumulation and acute tolerance.

  1988cited by this paper
• The influence of solution viscosity on nasal spray deposition and clearance

  1988cited by this paper
• Absorption of recombinant methionyl-human growth hormone (Met-hGH) from rat nasal mucosa

  1988cited by this paper
• Bioadhesive microspheres as a potential nasal drug delivery system

  1987cited by this paper
• Analysis of structural requirements for the absorption of drugs and macromolecules from the nasal cavity.

  1987influential reference
• Bile salts and intranasal drug absorption

  1986cited by this paper
• Ultrastructural morphology of the olfactory pathway for cerebrospinal fluid drainage in the rabbit.

  1986cited by this paper
• Metabolism of diethylnitrosamine by nasal mucosa and hepatic microsomes from hamster and rat: species specificity of nasal mucosa.

  1986cited by this paper
• Cytochrome P-450-dependent monooxygenase activity in nasal membranes of six species.

  1983cited by this paper
• Formaldehyde production promoted by rat nasal cytochrome P-450-dependent monooxygenases with nasal decongestants, essences, solvents, air pollutants, nicotine, and cocaine as substrates.

  1983cited by this paper
• Drainage of cerebral interstitial fluid into deep cervical lymph of the rabbit.

  1981cited by this paper
• Nasal absorption of propranolol in humans.

  1979cited by this paper
• Subarachnoid space of the CNS, nasal mucosa, and lymphatic system.

  1979cited by this paper
• Seasonal allergic rhinitis.

  1971cited by this paper

• Primary Mucosal Routes of Opioid Administration for Treating Terminal Cancer Pain: Rectal, Buccal, and Intranasal Delivery

  2026cites this paper
• Naloxone : l’antidote qui sauve des vies

  2025cites this paper
• Management of critically ill patients in austere environments: good clinical practice by the Italian Society of Anesthesia, Analgesia, Resuscitation and Intensive Care (SIAARTI)

  2024cites this paper
• Comparing the Efficacy of Fentanyl Nasal Packing on Postoperative Pain in Patients Undergoing Nasal Surgeries Versus Normal Saline Pack—A Randomized Control Trial

  2024cites this paper
• Opioids in Treatment of Refractory Dyspnea in Chronic Obstructive Pulmonary Disease: Yes, No or Maybe

  2024cites this paper
• Clinical evaluation of the sedative, antinociceptive and cardiorespiratory effects of intranasal dexmedetomidine combined with methadone in healthy dogs.

  2024cites this paper
• Clinical Pharmacokinetics and Pharmacodynamics of Naloxone

  2024influential citation
• Intranasal transmucosal drug delivery: An alternative approach to the parenteral route for medical emergencies

  2023cites this paper
• Fentanyl in cancer pain management: avoiding hasty judgments and discerning its potential benefits

  2023cites this paper
• Intranasal Fentanyl for Acute Pain Management in Children, Adults and Elderly Patients in the Prehospital Emergency Service and in the Emergency Department: A Systematic Review

  2023cites this paper
• Additive Value of Intranasal Fentanyl on Ibuprofen for Pain Management of Children With Moderate to Severe Headaches: A Randomized Controlled Trial.

  2023cites this paper
• Administration of Nebulised Ketamine for Managing Pain in the Intensive Care Unit of Obstetrics and Gynaecology

  2023cites this paper
• Polymeric nanocarriers for nose-to-brain drug delivery in neurodegenerative diseases and neurodevelopmental disorders

  2022cites this paper
• Intranasal Fentanyl for On-the-Hill Analgesia by Ski Patrol

  2022cites this paper
• Determination of the ED95 of intranasal sufentanil combined with intranasal dexmedetomidine for moderate sedation during endoscopic ultrasonography

  2022cites this paper
• Pharmacokinetic considerations for community-based dosing of nasal naloxone in opioid overdose in adults

  2022cites this paper
• Intranasal Fentanyl for First-Trimester Uterine Aspiration Pain:A Randomized Controlled Trial.

  2022cites this paper
• The Safety of High-Dose Intranasal Fentanyl in the Pediatric Emergency Department

  2022cites this paper
• IF IM in a crisis: Intranasal fentanyl versus intravenous morphine in adult vaso-occlusive crisis.

  2022cites this paper
• Tolerance of Fentanyl Pectin Nasal Spray for Procedural Pain in Geriatric Patients.

  2022cites this paper
• Pre-referral intranasal artesunate powder for cerebral malaria: a proof-of-concept study

  2022cites this paper
• Comparison of the sedative effects of intranasal or intramuscular dexmedetomidine at low doses in healthy dogs: a randomized clinical trial.

  2022cites this paper
• Intranasal drug delivery: opportunities and toxicologic challenges during drug development

  2021cites this paper
• Efficacy, safety, and tolerability of sublingual fentanyl orally disintegrating tablet in the treatment of breakthrough cancer pain: a randomized, double-blind, placebo-controlled study

  2021cites this paper
• Intranasal sufentanil compared with a classic protocol for acute pain management in an emergency department: A prospective sequential study

  2021cites this paper
• Effect of two surfactants on in vitro permeation of butorphanol through horse nasal mucosa

  2021cites this paper
• Mucus-producing 3D cell culture models.

  2021cites this paper
• Efficacy and Safety of Butorphanol Use in Patient-Controlled Analgesia: A Meta-Analysis

  2021cites this paper
• Short Onset and Enhanced Analgesia Following Nasal Administration of Non-Controlled Drugs in Nanovesicular Systems

  2021cites this paper
• Changes in Plasma Beta-Endorphin Levels in Stage III–IV Nasopharyngeal Carcinoma Patients Post World Health Organization 3-Step Analgesic Ladder Therapy

  2021cites this paper
• Combination of propofol and nasal sufentanil or intravenous midazolam for colonoscopy: a comparative study

  2021cites this paper
• Commonly used agent for acute pain management of sickle cell anemia in Saudi Emergency Department: A narrative review

  2021cites this paper
• Strategies for the delivery of antidiabetic drugs via intranasal route.

  2021cites this paper
• Inhaled Anesthetics and Draw-Over Devices in Disaster Response

  2020cites this paper
• SALT Triage Scheme

  2020cites this paper
• Chemical and Radiologic Exposures in Trauma and Disasters

  2020cites this paper
• Essentials of Disaster Anesthesia

  2020cites this paper
• Airway Management

  2020cites this paper
• Vascular Access, Hydration, and Fluids

  2020cites this paper
• Disaster Recovery Toolkit for Small Businesses

  2020cites this paper
• Strategic Packing v13.2

  2020cites this paper
• International Humanitarian Law

  2020cites this paper
• Disaster Anesthesia

  2020cites this paper
• Index

  2020cites this paper
• Preparing to Deploy to a Remote Disaster

  2020cites this paper
• Critical Care Delivery for Disasters in Austere Environments

  2020cites this paper
• Security in Disaster Anesthesia

  2020cites this paper
• Mass Spectrometric Imaging of the Brain Demonstrates the Regional Displacement of 6-Monoacetylmorphine by Naloxone

  2020cites this paper
• Pain in Disasters

  2020cites this paper
• Pharmacy in Disaster Anesthesia

  2020cites this paper
• Principles of Emergency and Trauma Surgery

  2020cites this paper
• Family Disaster Checklist and Plan

  2020cites this paper
• Power and Light: Impact of Electrical Systems Failure on the Delivery of Anesthetic Care

  2020cites this paper
• Considerations When Working with Children and Families

  2020cites this paper
• Disaster: Mental Health Effects, Responses, and What Clinicians Can Do

  2020cites this paper
• Laboratory Tests and Blood Banking

  2020cites this paper
• Quick Reference Guides for Mass Decontamination

  2020cites this paper
• High-Altitude Physiology and Anesthesia

  2020cites this paper
• Checklist for Trauma Anesthesia

  2020cites this paper
• Operating Room Procedures for Mass Casualty

  2020cites this paper
• Re-Opening Your Business: A Post-Disaster Checklist

  2020cites this paper
• Preface

  2020cites this paper
• Total Intravenous Anesthesia in Disaster Medicine

  2020cites this paper
• Special Populations: Children

  2020cites this paper
• Powered Air Purifying Respirator Placement

  2020cites this paper
• Austere Obstetric Anesthesia

  2020cites this paper
• Intranasal Agents in the emergency care: A systematic review

  2020cites this paper
• Children in Disasters

  2020cites this paper
• Radiology in the Austere or Disaster Environment

  2020cites this paper
• Communications

  2020cites this paper
• Operation Tomodachi: Anesthetic Implications

  2020cites this paper
• Regional Anesthesia in Disaster Circumstances

  2020cites this paper
• Draft Connecticut Acute Care Hospital Pediatric Disaster Preparedness Checklist

  2020cites this paper
• Current status and application of patient-controlled analgesia : a literature review

  2019cites this paper
• A Comparative Study of Post-Operative Analgesic Efficacy of Fentanyl, Butorphanol, Pethidine by Intranasal Route

  2019cites this paper
• Take-Home Naloxone for the Emergency Interim Management of Opioid Overdose: The Public Health Application of an Emergency Medicine

  2019cites this paper
• Intranasal Sufentanil Versus Intravenous Morphine for Acute Pain in the Emergency Department: A Randomized Pilot Trial.

  2019cites this paper
• Effect of fentanyl nasal packing treatment on patients with acute postoperative pain after closed reduction of nasal bone fracture: a randomized double-blind controlled trial

  2019cites this paper
• Safety of Intranasal Ketamine for Reducing Uncontrolled Cancer-Related Pain: Protocol of a Phase I/II Clinical Trial

  2019cites this paper
• Comparing Nonopioids Versus Opioids for Acute Pain in the Emergency Department: A Literature Review.

  2019cites this paper
• Intranasal Fentanyl and Midazolam for Procedural Analgesia and Anxiolysis in Pediatric Urgent Care Centers.

  2019cites this paper
• Why is the therapeutic effect of acute antimigraine drugs delayed? A review of controlled trials and hypotheses about the delay of effect

  2019cites this paper
• Baclofen-Loaded Poly (D,L-Lactide-Co-Glycolic Acid) Nanoparticles for Neuropathic Pain Management: In Vitro and In Vivo Evaluation

  2019cites this paper
• Intranasal Nanoparticulate Systems as Alternative Route of Drug Delivery.

  2019cites this paper
• Protocol Safety of Intranasal Ketamine for Reducing Uncontrolled Cancer-Related Pain : Protocol of a Phase I / II Clinical Trial

  2019cites this paper
• The Use of Intranasal Fentanyl for the Palliation of Incident Dyspnea in Advanced Congestive Heart Failure: A Pilot Study

  2018cites this paper
• Nanosystems in nose‐to‐brain drug delivery: A review of non‐clinical brain targeting studies

  2018cites this paper
• Interested in publishing with us ? Contact book

  2018cites this paper
• Intranasal Ketamine and Its Potential Role in Cancer‐Related Pain

  2018cites this paper
• Primjenjivost gelan gume u pripravi in situ gelirajućeg sustava za nazalnu primjenu lijekova

  2018cites this paper
• Treatment of pain with intranasal fentanyl in pediatric patients in an acute care setting: a systematic review.

  2018cites this paper
• Determination of the maximum tolerated dose of intranasal sufentanil and midazolam in Chinese: a pilot study

  2018cites this paper
• Association between intraoperative opioid administration and 30‐day readmission: a pre‐specified analysis of registry data from a healthcare network in New England

  2018cites this paper
• Effect of Fentanyl Nasal Packing Treatment on Patients With Acute Postoperative Pain After Nasal Operation: A Randomized Double-Blind Controlled Trial

  2018cites this paper
• Sedative and cardiovascular effects of intranasal or intramuscular dexmedetomidine in healthy dogs.

  2017cites this paper
• Analgesic Effect of Nebulized Versus Intravenous Fentanyl for Pain Relief of Limb Fracture: A Double-Blind Clinical Trial

  2017cites this paper
• The use of intranasal analgesia for acute pain control in the emergency department: A literature review

  2017cites this paper
• Does the Intranasal Route Pass the Sniff Test?

  2017cites this paper
• Patient-Controlled Analgesia (PCA) in Acute Pain: Pharmacological and Clinical Aspects

  2017cites this paper
• Intranasal fentanyl for initial treatment of vaso‐occlusive crisis in sickle cell disease

  2017cites this paper