Curcumin, both histone deacetylase and p300/CBP-specific inhibitor, represses the activity of nuclear factor kappa B and Notch 1 in Raji cells.

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Basic & Clinical Pharmacology & Toxicology

• Publication date

  2007-12-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1111/J.1742-7843.2007.00142.XPMID 17927689
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Notch1 augments NF‐κB activity by facilitating its nuclear retention

  2006cited by this paper
• Deguelin inhibits expression of IkappaBalpha protein in Raji and U937 cells.

  2006cited by this paper
• Notch1 augments NF-kappaB activity by facilitating its nuclear retention.

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• [Regulatory effect of curcumin on p300 and HDAC1 in B-NHL cells].

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• Deguelin inhibits expression of IκBα protein in Raji and U937 cells

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• Down-regulation of notch-1 inhibits invasion by inactivation of nuclear factor-kappaB, vascular endothelial growth factor, and matrix metalloproteinase-9 in pancreatic cancer cells.

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• Curcumin, a potent anti-tumor reagent, is a novel histone deacetylase inhibitor regulating B-NHL cell line Raji proliferation

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• Coactivators and Corepressors of NF-κB in IκBα Gene Promoter*

  2005cited by this paper
• Signaling to NF-kappaB.

  2004cited by this paper
• Notch‐1 regulates cell death independently of differentiation in murine erythroleukemia cells through multiple apoptosis and cell cycle pathways

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• Curcumin (diferuloylmethane) down-regulates the constitutive activation of nuclear factor-kappa B and IkappaBalpha kinase in human multiple myeloma cells, leading to suppression of proliferation and induction of apoptosis.

  2003cited by this paper
• Post-activation turn-off of NF-kappa B-dependent transcription is regulated by acetylation of p65.

  2003cited by this paper
• IκBα and p65 Regulate the Cytoplasmic Shuttling of Nuclear Corepressors: Cross-talk between Notch and NFκB Pathways

  2003cited by this paper
• IkappaBalpha and p65 regulate the cytoplasmic shuttling of nuclear corepressors: cross-talk between Notch and NFkappaB pathways.

  2003cited by this paper
• Post-activation Turn-off of NF-κB-dependent Transcription Is Regulated by Acetylation of p65*

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• Curcumin (diferuloylmethane) down-regulates the constitutive activation of nuclear factor–κB and IκBα kinase in human multiple myeloma cells, leading to suppression of proliferation and induction of apoptosis

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• Jagged-1 mediated activation of notch signaling induces complete maturation of human keratinocytes through NF-kappaB and PPARgamma.

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• Jagged-1 mediated activation of notch signaling induces complete maturation of human keratinocytes through NF-κB and PPARγ

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• Histone acetyltransferases.

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• Duration of Nuclear NF-κB Action Regulated by Reversible Acetylation

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• Duration of nuclear NF-kappaB action regulated by reversible acetylation.

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• Human Notch-1 Inhibits NF-κB Activity in the Nucleus Through a Direct Interaction Involving a Novel Domain1

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• p300 Acts as a Transcriptional Coactivator for Mammalian Notch-1

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• Notch signaling: cell fate control and signal integration in development.

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• Notch Signaling : Cell Fate Control and Signal Integration in Development

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