Orthopedic implant biomaterials with both osteogenic and anti-infection capacities and associated in vivo evaluation methods.

No abstract is available for this paper.

• Publication year

  2017

• Venue

  Nanomedicine : nanotechnology, biology, and medicine

• Publication date

  Unknown publication date

• Fields of study

  Medicine, Materials Science, Engineering

• Identifiers
  DOI 10.1016/j.nano.2016.08.003PMID 27553074
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Osteogenic ability of Cu-bearing stainless steel.

  2015cited by this paper
• Osteoblastic cell responses and antibacterial efficacy of Cu/Zn co-substituted hydroxyapatite coatings on pure titanium using electrodeposition method

  2015cited by this paper
• Antibacterial efficacy, corrosion resistance, and cytotoxicity studies of copper-substituted carbonated hydroxyapatite coating on titanium substrate

  2015cited by this paper
• Influence of Cu content on the cell biocompatibility of Ti-Cu sintered alloys.

  2015cited by this paper
• Enhanced antibacterial properties, biocompatibility, and corrosion resistance of degradable Mg-Nd-Zn-Zr alloy.

  2015cited by this paper
• Biocompatibility of ferroelectric lithium niobate and the influence of polarization charge on osteoblast proliferation and function.

  2015cited by this paper
• Alkalization is responsible for antibacterial effects of corroding magnesium.

  2015cited by this paper
• In vitro biodegradation behavior, mechanical properties, and cytotoxicity of biodegradable Zn-Mg alloy.

  2015cited by this paper
• Hydroxyapatite and demineralized calf fetal growth plate effects on bone healing in rabbit model

  2014cited by this paper
• Long-lasting in vivo and in vitro antibacterial ability of nanostructured titania coating incorporated with silver nanoparticles.

  2014cited by this paper
• Antibacterial Properties of Magnesium In Vitro and in an In Vivo Model of Implant-Associated Methicillin-Resistant Staphylococcus aureus Infection

  2014cited by this paper
• Antibacterial activity and cytocompatibility of titanium oxide coating modified by iron ion implantation.

  2014cited by this paper
• Enhanced antimicrobial properties, cytocompatibility, and corrosion resistance of plasma-modified biodegradable magnesium alloys.

  2014cited by this paper
• Silver nanoparticles and growth factors incorporated hydroxyapatite coatings on metallic implant surfaces for enhancement of osteoinductivity and antibacterial properties.

  2014cited by this paper
• Synergistic effects of dual Zn/Ag ion implantation in osteogenic activity and antibacterial ability of titanium.

  2014cited by this paper
• A histological and biomechanical study of bone stress and bone remodeling around immediately loaded implants

  2014cited by this paper
• Osteogenic activity and antibacterial effect of zinc ion implanted titanium.

  2014cited by this paper
• In Vivo Effect of Quaternized Chitosan-Loaded Polymethylmethacrylate Bone Cement on Methicillin-Resistant Staphylococcus epidermidis Infection of the Tibial Metaphysis in a Rabbit Model

  2014cited by this paper
• Controlled‐release of bone morphogenetic protein‐2 from a microsphere coating applied to acid‐etched Ti6AL4V implants increases biological bone growth in vivo

  2014cited by this paper
• Osteogenic activity of silver-loaded coral hydroxyapatite and its investigation in vivo

  2014cited by this paper
• Antibacterial Properties of Ti–6Al–4V–xCu Alloys

  2014cited by this paper
• Synthesis, structural analysis, mechanical, antibacterial and hemolytic activity of Mg²⁺ and Cu²⁺ co-substitutions in β-Ca₃(PO₄)₂.

  2014cited by this paper
• Fabrication of Ti–Nb–Ag alloy via powder metallurgy for biomedical applications

  2014cited by this paper
• Antibacterial activity and cytocompatibility of Cu-Ti-O nanotubes.

  2014cited by this paper
• Inhibitory effect of Ti-Ag alloy on artificial biofilm formation.

  2014cited by this paper
• Tailoring of antibacterial Ag nanostructures on TiO2 nanotube layers by magnetron sputtering.

  2014cited by this paper
• In vitro antibacterial capacity and cytocompatibility of SiO2-CaO-P2O5 meso-macroporous glass scaffolds enriched with ZnO.

  2014cited by this paper
• Surface functionalization of titanium substrates with chitosan-lauric acid conjugate to enhance osteoblasts functions and inhibit bacteria adhesion.

  2014cited by this paper
• Enhanced osseointegration and antibacterial action of zinc-loaded titania-nanotube-coated titanium substrates: in vitro and in vivo studies.

  2014cited by this paper
• Antibacterial property, angiogenic and osteogenic activity of Cu-incorporated TiO2 coating.

  2014cited by this paper
• In vitro and in vivo anti-biofilm effects of silver nanoparticles immobilized on titanium.

  2014cited by this paper
• Synthesis, structure, thermal stability, mechanical and antibacterial behaviour of lanthanum (La³⁺) substitutions in β-tricalciumphosphate.

  2014cited by this paper
• Tailoring of antibacterial Ag nanostructures on TiO2 nanotube layers by magnetron sputtering

  2014cited by this paper
• Effect of Cu content on the antibacterial activity of titanium-copper sintered alloys.

  2014cited by this paper
• Understanding of dopant-induced osteogenesis and angiogenesis in calcium phosphate ceramics.

  2013cited by this paper
• Silver oxide‐containing hydroxyapatite coating has in vivo antibacterial activity in the rat tibia

  2013cited by this paper
• Antibacterial biodegradable Mg-Ag alloys.

  2013cited by this paper
• Functionalizing Calcium Phosphate Biomaterials with Antibacterial Silver Particles

  2013cited by this paper
• Copper-containing mesoporous bioactive glass scaffolds with multifunctional properties of angiogenesis capacity, osteostimulation and antibacterial activity.

  2013cited by this paper
• Quaternized Chitosan as an Antimicrobial Agent: Antimicrobial Activity, Mechanism of Action and Biomedical Applications in Orthopedics

  2013cited by this paper
• Magnesium Alloy for Repair of Lateral Tibial Plateau Defect in Minipig Model

  2013cited by this paper
• Silver and fluoride doped hydroxyapatites: Investigation by microstructure, mechanical and antibacterial properties

  2013cited by this paper
• Biodegradable magnesium-based screw clinically equivalent to titanium screw in hallux valgus surgery: short term results of the first prospective, randomized, controlled clinical pilot study

  2013cited by this paper
• PolyNaSS grafting on titanium surfaces enhances osteoblast differentiation and inhibits Staphylococcus aureus adhesion

  2013cited by this paper
• Critical factors in the translation of improved antimicrobial strategies for medical implants and devices.

  2013cited by this paper
• A Model of Implant-Associated Infection in the Tibial Metaphysis of Rats

  2013cited by this paper
• Effectiveness of synthetic hydroxyapatite versus Persian Gulf coral in an animal model of long bone defect reconstruction

  2013cited by this paper
• A rabbit osteomyelitis model for the longitudinal assessment of early post-operative implant infections

  2013cited by this paper
• Chitosan‐heparin polyelectrolyte multilayers on cortical bone: Periosteum‐mimetic, cytophilic, antibacterial coatings

  2013cited by this paper
• A Silver Ion-doped Calcium Phosphate-based Ceramic Nanopowder-coated Prosthesis Increased Infection Resistance

  2013cited by this paper
• Silver-containing mesoporous bioactive glass with improved antibacterial properties

  2013cited by this paper
• Designing antimicrobial bioactive glass materials with embedded metal ions synthesized by the sol-gel method.

  2013cited by this paper
• A new antibacterial titanium-copper sintered alloy: preparation and antibacterial property.

  2013cited by this paper
• In vitro cytotoxicity evaluation of porous TiO₂-Ag antibacterial coatings for human fetal osteoblasts.

  2012cited by this paper
• Preliminary study of anti-infective function of a copper-bearing stainless steel

  2012cited by this paper
• Balancing osteoblast functions and bacterial adhesion on functionalized titanium surfaces.

  2012cited by this paper
• Modulation of osteogenic differentiation in hMSCs cells by submicron topographically-patterned ridges and grooves.

  2012cited by this paper
• Hydrophobic polycationic coatings that inhibit biofilms and support bone healing during infection.

  2012cited by this paper
• Antibacterial activity and increased bone marrow stem cell functions of Zn-incorporated TiO2 coatings on titanium.

  2012cited by this paper
• Surface properties of titanium and zirconia dental implant materials and their effect on bacterial adhesion.

  2012cited by this paper
• Effects of extrusion and heat treatment on the mechanical properties and biocorrosion behaviors of a Mg-Nd-Zn-Zr alloy.

  2012cited by this paper
• Microstructure, mechanical properties, biocorrosion behavior, and cytotoxicity of as-extruded Mg-Nd-Zn-Zr alloy with different extrusion ratios.

  2012cited by this paper
• Decreased bacteria activity on Si3N4 surfaces compared with PEEK or titanium

  2012cited by this paper
• Antibacterial and biological characteristics of silver containing and strontium doped plasma sprayed hydroxyapatite coatings.

  2012cited by this paper
• Orthopedic applications of silicon nitride ceramics.

  2012cited by this paper
• Anti-infective and osteointegration properties of silicon nitride, poly(ether ether ketone), and titanium implants.

  2012cited by this paper
• Review of titania nanotubes: Fabrication and cellular response

  2012cited by this paper
• Antibacterial effect of sand blasted, large-grit, acid-etched treated Ti–Ag alloys

  2012cited by this paper
• The effect of antibacterial ingredients and coating microstructure on the antibacterial properties of plasma sprayed hydroxyapatite coatings

  2012cited by this paper
• The use of quaternised chitosan-loaded PMMA to inhibit biofilm formation and downregulate the virulence-associated gene expression of antibiotic-resistant staphylococcus.

  2012cited by this paper
• Enhanced biological responses of a hydroxyapatite/TiO2 hybrid structure when surface electric charge is controlled using radiofrequency sputtering.

  2012cited by this paper
• Physical characterization and osteogenic activity of the quaternized chitosan-loaded PMMA bone cement.

  2012cited by this paper
• Modulation of osteogenic, adipogenic and myogenic differentiation of mesenchymal stem cells by submicron grooved topography

  2012cited by this paper
• Size-dependent bacterial growth inhibition and mechanism of antibacterial activity of zinc oxide nanoparticles.

  2011cited by this paper
• Effect of electrical polarization and composition of biphasic calcium phosphates on early stage osteoblast interactions.

  2011cited by this paper
• Metallic ions as therapeutic agents in tissue engineering scaffolds: an overview of their biological applications and strategies for new developments

  2011cited by this paper
• Bioinorganics and biomaterials: bone repair.

  2011cited by this paper
• Early bone growth on the surface of titanium implants in rat femur is enhanced by an amorphous diamond coating

  2011cited by this paper
• Antibacterial nano-structured titania coating incorporated with silver nanoparticles.

  2011cited by this paper
• Differential attraction and repulsion of Staphylococcus aureus and Pseudomonas aeruginosa on molecularly smooth titanium films

  2011cited by this paper
• A review of the biological response to ionic dissolution products from bioactive glasses and glass-ceramics.

  2011cited by this paper
• Bone-implant interface strength and osseointegration: Biodegradable magnesium alloy versus standard titanium control.

  2011cited by this paper
• Differential response of Staphylococci and osteoblasts to varying titanium surface roughness.

  2011cited by this paper
• Free form fabricated features on CoCr implants with and without hydroxyapatite coating in vivo: a comparative study of bone contact and bone growth induction

  2011cited by this paper
• Mechanical and corrosion properties of newly developed biodegradable Zn-based alloys for bone fixation.

  2011cited by this paper
• Synthesis of antimicrobial monophase silver-doped hydroxyapatite nanopowders for bone tissue engineering

  2011cited by this paper
• Differential scanning calorimetry analysis on Cu precipitation in a high Cu austenitic stainless steel

  2011cited by this paper
• Antibacterial effect of 317L stainless steel contained copper in prevention of implant-related infection in vitro and in vivo

  2011cited by this paper
• Porous titanium granules promote bone healing and growth in rabbit tibia peri-implant osseous defects.

  2010cited by this paper
• Impact of nanoscale roughness of titanium thin film surfaces on bacterial retention.

  2010cited by this paper
• Response of osteoblast-like SAOS-2 cells to zirconia ceramics with different surface topographies.

  2010cited by this paper
• The relationship between the nanostructure of titanium surfaces and bacterial attachment.

  2010cited by this paper
• Fabrication of porous chitosan films impregnated with silver nanoparticles: a facile approach for superior antibacterial application.

  2010cited by this paper
• Electrically polarized HAp-coated Ti: in vitro bone cell-material interactions.

  2010cited by this paper
• Synthesis, characterization and antimicrobial activity of copper and zinc-doped hydroxyapatite nanopowders

  2010cited by this paper
• An in vivo evaluation of bone response to three implant surfaces using a rabbit intramedullary rod model

  2010cited by this paper
• Metallic Copper as an Antimicrobial Surface

  2010cited by this paper
• Visible-light-induced bactericidal activity of titanium dioxide codoped with nitrogen and silver.

  2010cited by this paper
• Investigations into the antibacterial behavior of copper nanoparticles against Escherichia coli

  2010cited by this paper
• Antibacterial coatings of fluoridated hydroxyapatite for percutaneous implants.

  2010cited by this paper

• Dual-functional titanium implants via polydopamine-mediated lithium and copper co-incorporation: synergistic enhancement of osseointegration and antibacterial efficacy

  2025cites this paper
• Multifunctional PEEK implants via mussel adhesion-mediated assembly for osteoimmune regulation and antibacterial properties

  2025cites this paper
• Novel Foamed Magnesium Phosphate Antimicrobial Bone Cement for Bone Augmentation.

  2025cites this paper
• Enhancing the Implant Osteointegration via Supramolecular Co‐Assembly Coating with Early Immunomodulation and Cell Colonization

  2025cites this paper
• Physical, mechanical, and bioactive investigation of marble dust and silver reinforced NiTi hybrid composite

  2025cites this paper
• Carbon-based composites in biomedical applications: a comprehensive review of properties, applications, and future directions

  2024cites this paper
• Porcine Mandibular Bone Marrow-Derived Mesenchymal Stem Cell (BMSC)-Derived Extracellular Vesicles Can Promote the Osteogenic Differentiation Capacity of Porcine Tibial-Derived BMSCs

  2024cites this paper
• Revolutionizing medical implant fabrication: advances in additive manufacturing of biomedical metals

  2024cites this paper
• Enhancing the immunomodulatory osteogenic properties of Ti-Mg alloy by Mg2+-containing nanostructures

  2024cites this paper
• Tailoring microenvironment responsive Fe/Cu micro-galvanic couples on polyetheretherketone for selective antibacteria and osteogenesis

  2024cites this paper
• Challenges and Pitfalls of Research Designs Involving Magnesium-Based Biomaterials: An Overview

  2024cites this paper
• Surface engineering of pure magnesium in medical implant applications

  2024cites this paper
• Study of the Preparation and Properties of Biomedical Ti–Mg Composites

  2024cites this paper
• Coating of manganese functional polyetheretherketone implants for osseous interface integration

  2023influential citation
• Immunological mechanism of Sr/Cu ion synergistically promote implant osseointegration

  2023cites this paper
• Realizing Both Antibacterial Activity and Cytocompatibility in Silicocarnotite Bioceramic via Germanium Incorporation

  2023cites this paper
• Review on magnesium and magnesium-based alloys as biomaterials for bone immobilization

  2023cites this paper
• Theoretical modeling approach for adsorption of fibronectin on the nanotopographical implants

  2023cites this paper
• β duplex phase Ti-Zr-Nb-Ag alloys with impressive mechanical properties, excellent antibacterial and good biocompatibility

  2022cites this paper
• Biodegradable Mg-based alloys: biological implications and restorative opportunities

  2022cites this paper
• Shellac: A Bioactive Coating for Surface Engineering of Cardiovascular Devices

  2022cites this paper
• Current Knowledge on Biomaterials for Orthopedic Applications Modified to Reduce Bacterial Adhesive Ability

  2022cites this paper
• Osseointegration Assessment of Multi‐Material Ti6Al4V‐β TCP Implants: An Experimental Study in Rats

  2022cites this paper
• NiTi laser textured implants with improved in vivo osseointegration: An experimental study in rats

  2022cites this paper
• Chitosan/vancomycin antibacterial hydrogel for application in knee prostheses

  2022cites this paper
• The application of biomaterials in osteogenesis: A bibliometric and visualized analysis

  2022cites this paper
• A silane-based coupling strategy for enhancing the mechanical properties of proanthocyanidin nanocoatings on Ti dental implants

  2022cites this paper
• Hybrid fabrication of photo-clickable vascular hydrogels with additive manufactured titanium implants for enhanced osseointegration and vascularized bone formation

  2022cites this paper
• Study on TiO2 Nanofilm That Reduces the Heat Production of Titanium Alloy Implant in Microwave Irradiation and Does Not Affect Fracture Healing

  2022cites this paper
• Antibacterial surfaces: Strategies and applications

  2022cites this paper
• Enhancement of Physical and Mechanical Characteristics of NiTi Composite Containing Ag and TiC

  2021cites this paper
• Development of hydrofluoric acid-cleaned silicon nitride implants for periprosthetic infection eradication and bone regeneration enhancement.

  2021cites this paper
• A comprehensive review on techniques to create the anti-microbial surface of biomaterials to intervene in biofouling

  2021cites this paper
• Multifunctional Titanium Surfaces for Orthopedic Implants: Antimicrobial Activity and Enhanced Osseointegration.

  2021cites this paper
• Antibacterial surface design of biomedical titanium materials for orthopedic applications

  2021cites this paper
• Cu-decorated graphene oxide coatings with enhanced antibacterial activity for surface modification of implant

  2021cites this paper
• Bimetallic ions regulated PEEK of bone implantation for antibacterial and osteogenic activities

  2021cites this paper
• Preclinical In Vitro Assessment of Submicron-Scale Laser Surface Texturing on Ti6Al4V

  2020cites this paper
• Surface modification of β-type titanium with multi-walled CNTs/ μ-HAp powder mixed Electro Discharge Treatment process

  2020cites this paper
• Silver-substituted hydroxyapatite

  2020cites this paper
• Combined Infection Control and Enhanced Osteogenic Differentiation Capacity on Additive Manufactured Ti‐6Al‐4V are Mediated via Titania Nanotube Delivery of Novel Biofilm Inhibitors

  2020cites this paper
• Development of systemic immune dysregulation in a rat trauma model of biomaterial-associated infection.

  2020cites this paper
• Halloysite nanotubes loaded with nano silver for the sustained-release of antibacterial polymer nanocomposite scaffolds

  2020cites this paper
• The effect of teicoplanin coating on osteointegration of titanium screws: a biomechanical and histomorphometric study in a rabbit model

  2020cites this paper
• Bacterial adhesion on orthopedic implants.

  2020cites this paper
• Enhancing antibacterial performance and biocompatibility of pure titanium by a two-step electrochemical surface coating.

  2020cites this paper
• Stimulation of in vitro and in vivo osteogenesis by Ti-Mg composite materials with the sustained-release function of magnesium ions.

  2020cites this paper
• Ceramic Coating in Cemented Primary Total Knee Arthroplasty is Not Associated With Decreased Risk of Revision due to Early Prosthetic Joint Infection.

  2020cites this paper
• Smart Titanium Coating Composed of Antibiotic Conjugated Peptides as an Infection-Responsive Antibacterial Agent.

  2020cites this paper
• Chitin and chitosan composites for bone tissue regeneration

  2020cites this paper
• Biofilm Formation and Expression of Virulence Genes of Microorganisms Grown in Contact with a New Bioactive Glass

  2020cites this paper
• Antibacterial, proangiogenic, and osteopromotive nanoglass paste coordinates regenerative process following bacterial infection in hard tissue.

  2020cites this paper
• BIODEGRADABLE ZINC ALLOYS AND COMPOSITES FOR BIOMEDICAL APPLICATION: AN OVERVIEW OF PROCESSING ROUTES AND POSSIBLE FUTURE WORK

  2020cites this paper
• Laser engineered net shaping of antimicrobial and biocompatible titanium-silver alloys.

  2019cites this paper
• Biological Response of and Blood Plasma Protein Adsorption on Silver-Doped Hydroxyapatite.

  2019cites this paper
• Effect of Au addition on the corrosion activity of Ca-Mg-Zn bulk metallic glasses in Ringer's solution

  2019cites this paper
• Bi-functional titanium-polydopamine-zinc coatings for infection inhibition and enhanced osseointegration

  2019cites this paper
• Titania nanotube-based protein delivery system to inhibit cranial bone regeneration in Crouzon model of craniosynostosis

  2019cites this paper
• The Effect of Deposition Time on Ag-Zn Thin Film Forming Using RF Sputtering for Antimicrobial Coating Orthopedic Devices

  2019cites this paper
• Enhancement of bone consolidation using high-frequency pulsed electromagnetic short-waves and titanium implants coated with biomimetic composite embedded into PLA matrix: in vivo evaluation

  2019cites this paper
• Surface functionalization of titanium with zinc/strontium-doped titanium dioxide microporous coating via microarc oxidation.

  2019cites this paper
• Biomineralization, antibacterial activity and mechanical properties of biowaste derived diopside nanopowders

  2019cites this paper
• Clinical, industrial, and research perspectives on powder bed fusion additively manufactured metal implants

  2019cites this paper
• Surface degradation–enabled osseointegrative, angiogenic and antiinfective properties of magnesium-modified acrylic bone cement

  2019cites this paper
• Mechanical Properties of Powder Metallurgy Processed Biodegradable Zn-Based Alloy for Biomedical Application

  2019cites this paper
• Advances in Dual Functional Antimicrobial and Osteoinductive Biomaterials for Orthopedic Applications.

  2019cites this paper
• Experimental model of peri-prosthetic infection of the knee caused by Staphylococcus aureus using biomaterials representative of modern TKA

  2019cites this paper
• Biofunctional Sr- and Si-loaded titania nanotube coating of Ti surfaces by anodization-hydrothermal process

  2018cites this paper
• Fabrication and Characterizations of Metallic Mg Containing PMMA-Based Partially Degradable Composite Bone Cements

  2018cites this paper
• Enhancing Corrosion Resistance, Osteoinduction, and Antibacterial Properties by Zn/Sr Additional Surface Modification of Magnesium Alloy.

  2018cites this paper
• Influence of reinforcements in friction stir processed magnesium alloys: insight in medical applications

  2018cites this paper
• Microstructural and mechanical analysis of 316L SS/ β-TCP composites produced though the powder metallurgy route

  2018cites this paper
• Lactic acid of PLGA coating promotes angiogenesis on the interface between porous titanium and diabetic bone.

  2018cites this paper
• Antibacterial effects, biocompatibility and electrochemical behavior of zinc incorporated niobium oxide coating on 316L SS for biomedical applications

  2018cites this paper
• Antibacterial Activity and Biocompatibility of Nanoporous Titanium Doped with Silver Nanoparticles and Coated with N-Acetyl Cysteine

  2018cites this paper
• Degradation Products of Polydopamine Restrained Inflammatory Response of LPS-Stimulated Macrophages Through Mediation TLR-4-MYD88 Dependent Signaling Pathways by Antioxidant

  2018cites this paper
• Antibacterial forsterite (Mg2SiO4) scaffold: A promising bioceramic for load bearing applications

  2018cites this paper
• Carboxymethyl chitosan–zinc coating for prevention of pin tract infection: An animal model

  2018cites this paper
• Novel functionalized nanoparticles for tumor-targeting co-delivery of doxorubicin and siRNA to enhance cancer therapy

  2017cites this paper