Gonadal steroids and humoral immunity

No abstract is available for this paper.

• Publication year

  2013

• Venue

  Nature Reviews Endocrinology

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1038/nrendo.2012.206PMID 23183675
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Differential Roles of Estrogen Receptors α and β in Control of B-Cell Maturation and Selection

  2011cited by this paper
• B-lymphocyte commitment: identifying the point of no return.

  2011cited by this paper
• Differential regulation of self-reactivity discriminates between IgG+ human circulating memory B cells and bone marrow plasma cells

  2011cited by this paper
• AID dysregulation in lupus-prone MRL/Faslpr/lpr mice increases class switch DNA recombination and promotes interchromosomal c-Myc/IgH loci translocations: Modulation by HoxC4

  2011cited by this paper
• Abrogation of pathogenic IgG autoantibody production in CD40L gene-deleted lupus-prone New Zealand Black mice.

  2011cited by this paper
• Expression of Humoral Autoimmunity is Related to Androgen Receptor CAG Repeat Length in Men with Systemic Lupus Erythematosus

  2011cited by this paper
• Checkpoints in lymphocyte development and autoimmune disease

  2010cited by this paper
• Estrogen Receptors Bind to and Activate the HOXC4/HoxC4 Promoter to Potentiate HoxC4-mediated Activation-induced Cytosine Deaminase Induction, Immunoglobulin Class Switch DNA Recombination, and Somatic Hypermutation*

  2010cited by this paper
• Activation‐induced deaminase heterozygous MRL/lpr mice are delayed in the production of high‐affinity pathogenic antibodies and in the development of lupus nephritis

  2009cited by this paper
• Susceptibility to autoimmunity and B cell resistance to apoptosis in mice lacking androgen receptor in B cells.

  2009cited by this paper
• Estrogen directly activates AID transcription and function

  2009cited by this paper
• Lupus-prone MRL/faslpr/lpr mice display increased AID expression and extensive DNA lesions, comprising deletions and insertions, in the immunoglobulin locus: Concurrent upregulation of somatic hypermutation and class switch DNA recombination

  2009cited by this paper
• Progesterone Inhibits Activation-Induced Deaminase by Binding to the Promoter1

  2009cited by this paper
• HoxC4 binds to the Aicda promoter to induce AID expression, class switch DNA recombination and somatic hypermutation

  2009cited by this paper
• Soluble Frizzled-Related Protein 1 Is Estrogen Inducible in Bone Marrow Stromal Cells and Suppresses the Earliest Events in Lymphopoiesis1

  2008cited by this paper
• The biochemistry of somatic hypermutation.

  2008cited by this paper
• Mechanism and regulation of class switch recombination.

  2008cited by this paper
• Molecular mechanisms of antibody somatic hypermutation.

  2007cited by this paper
• B-cell self-tolerance in humans.

  2007cited by this paper
• Abrogation of Lupus Nephritis in Activation-Induced Deaminase-Deficient MRL/lpr Mice1

  2007cited by this paper
• A checkpoint for autoreactivity in human IgM+ memory B cell development

  2006cited by this paper
• Cutting Edge: Hormonal Milieu, Not Antigenic Specificity, Determines the Mature Phenotype of Autoreactive B Cells1

  2006cited by this paper
• Toll-like receptors in systemic autoimmune disease

  2006cited by this paper
• Induction of tolerance in arthritogenic B cells with receptors of differing affinity for self-antigen.

  2006cited by this paper
• Protein array autoantibody profiles for insights into systemic lupus erythematosus and incomplete lupus syndromes

  2006cited by this paper
• Hormonal Regulation of B Cell Development: 17β-Estradiol Impairs Negative Selection of High-Affinity DNA-Reactive B Cells at More Than One Developmental Checkpoint1

  2006cited by this paper
• Hormonal modulation of B cell development and repertoire selection.

  2005cited by this paper
• Ongoing Immunoglobulin Class Switch DNA Recombination in Lupus B Cells: Analysis of Switch Regulatory Regions

  2004cited by this paper
• B cell receptor signal strength determines B cell fate

  2004cited by this paper
• Predominant Autoantibody Production by Early Human B Cell Precursors

  2003cited by this paper
• Oestrogen receptor specificity in oestradiol‐mediated effects on B lymphopoiesis and immunoglobulin production in male mice

  2003cited by this paper
• Estrogen alters thresholds for B cell apoptosis and activation.

  2002cited by this paper
• Characteristics of early murine B-lymphocyte precursors and their direct sensitivity to negative regulators.

  2001cited by this paper
• B cell development pathways.

  2001cited by this paper
• The follicular versus marginal zone B lymphocyte cell fate decision is regulated by Aiolos, Btk, and CD21.

  2001cited by this paper
• Cutting Edge: Expansion and Activation of A Population of Autoreactive Marginal Zone B Cells in a Model of Estrogen-Induced Lupus

  2001cited by this paper
• Bone marrow stromal cells mediate androgenic suppression of B lymphocyte development.

  2001cited by this paper
• Identification of very early lymphoid precursors in bone marrow and their regulation by estrogen

  2001cited by this paper
• Linking class-switch recombination with somatic hypermutation

  2001cited by this paper
• Estrogen up-regulates Bcl-2 and blocks tolerance induction of naive B cells.

  2000cited by this paper
• Estrogen influences the differentiation, proliferation, and survival of early B-lineage precursors.

  2000cited by this paper
• Early B‐lymphocyte precursors and their regulation by sex steroids

  2000cited by this paper
• Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme.

  2000cited by this paper
• Role of Estrogen Receptor α in Hematopoietic Stem Cell Development and B Lymphocyte Maturation in the Male Mouse.

  2000cited by this paper
• Role of estrogen receptor alpha in hematopoietic stem cell development and B lymphocyte maturation in the male mouse.

  2000cited by this paper
• The role of estrogen receptors and androgen receptors in sex steroid regulation of B lymphopoiesis.

  1998cited by this paper
• Androgens alter B cell development in normal male mice.

  1997cited by this paper
• Estrogen deficiency stimulates B lymphopoiesis in mouse bone marrow.

  1994cited by this paper
• Increased B lymphopoiesis in genetically sex steroid-deficient hypogonadal (hpg) mice

  1994cited by this paper
• Pregnancy-related steroids are potential negative regulators of B lymphopoiesis.

  1994cited by this paper
• Suppression of B lymphopoiesis during normal pregnancy

  1993cited by this paper
• Receptor editing in self-reactive bone marrow B cells

  1993cited by this paper
• Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genes

  1989cited by this paper
• Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice

  1988cited by this paper
• Sex hormone modulation of autoimmunity in NZB/NZW mice.

  1979cited by this paper
• Effect of castration and sex hormone treatment on survival, anti- nucleic acid antibodies, and glomerulonephritis in NZB/NZW F1 mice

  1978cited by this paper
• Androgenic hormones modulate autoantibody responses and improve survival in murine lupus.

  1977cited by this paper
• STUDIES OF THE REGULATORY EFFECTS OF THE SEX HORMONES ON ANTIBODY FORMATION AND STEM CELL DIFFERENTIATION

  1972cited by this paper
• Regulation of the antibody response

  1971cited by this paper
• Measurement of Antibody-Producing Capacity in Man

  1971cited by this paper
• Measurement of antibody-producing capacity in man. I. The normal response to flagellin from Salmonella adelaide.

  1969cited by this paper
• Difference in the immunoglobulin class of polioantibody in the serum of men and women.

  1968cited by this paper
• Influence of Sex on Immunoglobulin Levels

  1967cited by this paper
• Effect of estrogen and cortisone on immune hemoantibodies in mice of inbred strains.

  1955cited by this paper
• The Effect of Estrone on Antibody-Production

  1942cited by this paper
• The Effect of Estrogenic Hormone and Ovariectomy on the Normal Antibody Content of the Serum of Mature Rabbits *

  1939cited by this paper
• Effect of Gonadotropic and Oestrogenic Hormones on Agglutinin Response to B. Pertussis in Immature Animals

  1936cited by this paper
• The Relationship of Age to Immunological Reactions *

  1934cited by this paper
• Einfluß der Entfernung von Drüsen mit innerer Sekretion auf die Antikörperbildung

  1924cited by this paper

• Urticaria and Urticaria-like Dermatoses in Pregnancy: Clinical Spectrum, Differential Diagnosis and Management

  2026cites this paper
• TFOS DEWS III.

  2025cites this paper
• The toll like receptor 7 pathway and the sex bias of systemic lupus erythematosus

  2025cites this paper
• TFOS DEWS III Digest Report.

  2025cites this paper
• The prevalence of autoimmune thyroiditis is not increased in women with polycystic ovary syndrome after adjustment for family predisposition

  2025cites this paper
• Menopause and gastrointestinal health and disease

  2025cites this paper
• The Impact of Microbiota–Immunity–Hormone Interactions on Autoimmune Diseases and Infection

  2024cites this paper
• Torque teno virus: a potential marker of immune reconstitution in youths with vertically acquired HIV

  2024cites this paper
• The Impact of Immune System Aging on Infectious Diseases

  2024cites this paper
• Real-world effectiveness of the CoronaVac vaccine in a retrospective population-based cohort in four Colombian Cities 2021-2022.

  2024cites this paper
• Autoimmunity associates with severity of illness in elderly patients with drug-induced liver injury

  2023cites this paper
• Abcc8 (sulfonylurea receptor-1) knockout mice exhibit reduced axonal injury, cytotoxic edema and cognitive dysfunction vs. wild-type in a cecal ligation and puncture model of sepsis

  2023cites this paper
• Activation of GPER1 in macrophages ameliorates UUO-induced renal fibrosis

  2023cites this paper
• Role of Sex Hormones in Prevalent Kidney Diseases

  2023cites this paper
• Characteristics of steroid hormones in systemic lupus erythematosus revealed by GC/MS-based metabolic profiling

  2023cites this paper
• Rapid Assessment of Insect Steroid Hormone Entry Into Cultured Cells

  2022cites this paper
• Potential immunological effects of gender-affirming hormone therapy in transgender people – an unexplored area of research

  2022cites this paper
• Sex bias in lymphocytes: Implications for autoimmune diseases

  2022influential citation
• Immunomodulatory effects of Bacillus subtilis-fermented soybean extract in mice

  2022cites this paper
• Land use influences human mental and respiratory health in a conservation priority area in southeastern Brazil

  2022cites this paper
• Sex and Gender Differences in Bacterial Infections

  2022cites this paper
• Serum IL-1ra Is Associated with but Has No Genetic Link to Type 1 Diabetes

  2022cites this paper
• Deficiency of mature B cells does not alter the atherogenic response to castration in male mice

  2022cites this paper
• Sex disparity and drug-induced liver injury.

  2022cites this paper
• The immune response to COVID‐19: Does sex matter?

  2022cites this paper
• Machine-learning-aided identification of steroid hormones based on the anisotropic galvanic replacement generated sensor array

  2022cites this paper
• Role of hormones in the pregnancy and sex‐specific outcomes to infections with respiratory viruses *

  2022cites this paper
• Fracture-related infection in osteoporotic bone causes more severe infection and further delays healing

  2022cites this paper
• Sex, Allergic Diseases and Omalizumab

  2022cites this paper
• Propensity-Score Analysis Reveals that Sex is Not a Prognosis Factor for Mortality in Intensive Care Unit-Admitted Patients with Septic Bacteremia.

  2021cites this paper
• Sex Differences in Differentiated Thyroid Cancer

  2021cites this paper
• Systemic lupus erythematosus in children and adults: A retrospective study in Brazilian patients

  2021cites this paper
• Propensity-Score Analysis Reveals that Sex is Not a Prognosis Factor for Mortality in Intensive Care Unit-Admitted Patients with Sepsis

  2021cites this paper
• The influence of hepatitis B virus infection in pregnant women

  2021influential citation
• Assessing sex differential in COVID-19 mortality rate by age and polymerase chain reaction test results: an Iranian multi-center study

  2021cites this paper
• SARS-CoV-2 vaccination responses in untreated, conventionally treated and anticytokine-treated patients with immune-mediated inflammatory diseases

  2021cites this paper
• Disease Severity, Fever, Age, and Sex Correlate With SARS-CoV-2 Neutralizing Antibody Responses

  2021cites this paper
• Progestogens and Autoimmunity

  2021cites this paper
• Immunosenescence and inflammaging in the aging process: age-related diseases or longevity?

  2021cites this paper
• Effects of Hormone Therapy and Flavonoids Capable on Reversal of Menopausal Immune Senescence

  2021cites this paper
• Estrogen Signaling Based Current and Potential Therapies Against Obesity and Related Diseases

  2021cites this paper
• Expression of Sex Hormone Receptor and Immune Response Genes in Peripheral Blood Mononuclear Cells During the Menstrual Cycle

  2021cites this paper
• The bone is the major source of high circulating intact fibroblast growth factor-23 in acute murine polymicrobial sepsis induced by cecum ligation puncture

  2021cites this paper
• Kinetic Characteristics of Neutralizing Antibody Responses Vary among Patients with COVID-19

  2021cites this paper
• Sex Bias in Systemic Lupus Erythematosus and Sjögren’s Syndrome

  2020cites this paper
• Long-term exposure to low 17α-ethinylestradiol (EE2) concentrations disrupts both the reproductive and the immune system of juvenile rainbow trout, Oncorhynchus mykiss.

  2020cites this paper
• Considering how biological sex impacts immune responses and COVID-19 outcomes

  2020cites this paper
• Sex Differences in Case Fatality Rate of COVID-19: Insights From a Multinational Registry

  2020cites this paper
• A systematic review on current osteosynthesis-associated infection animal fracture models

  2020cites this paper
• Immunological, vascular and metabolic actions of androgens

  2020cites this paper
• Gender differences in the severity and features of lesions among Cutaneous Leishmaniasis patients

  2020cites this paper
• Gender differences in Community-acquired Pneumonia.

  2020cites this paper
• The international epidemiological transition and the education gender gap

  2020cites this paper
• The international epidemiological transition and the education gender gap

  2020cites this paper
• Effect of sex on clinical outcomes in COVID-19 patients: a population-based study

  2020cites this paper
• Effect of Sex on Clinical Outcomes in Patients with Coronavirus Disease: A Population-Based Study

  2020cites this paper
• Blood hormones and torque teno virus in peripheral blood mononuclear cells

  2020cites this paper
• Crystal structure of steroid reductase SRD5A reveals conserved steroid reduction mechanism

  2020cites this paper
• Sex differences in neuro(auto)immunity and chronic sciatic nerve pain

  2020cites this paper
• Increased estrogen to androgen ratio enhances immunoglobulin levels and impairs B cell function in male mice

  2020cites this paper
• Cardiac Diseases in Pregnancy Antibiotic Prescription Antenatal Care Services Epithelial Ovarian Tumours Low Back Pain Regional Anaesthesia in Children Somatisation Nigella sativa and Essential Tremor Neonatal Conjunctivitis Long Term Non-Progressive HIV Infection

  2020cites this paper
• Beyond dexamethasone, emerging immuno‐thrombotic therapies for COVID‐19

  2020cites this paper
• The Patient's Gender Influencing the Accuracy of Diagnosis and Proposed Sepsis Treatment in Constructed Cases

  2020cites this paper
• Updated advances of linking psychosocial factors and sex hormones with systemic lupus erythematosus susceptibility and development

  2019cites this paper
• The Effect of Female Pheromone on the Functional State of Young Men

  2019cites this paper
• Selective Sexual Dimorphisms in Musculoskeletal and Cardiopulmonary Pathologic Manifestations and Mortality Incidence in the Tumor Necrosis Factor–Transgenic Mouse Model of Rheumatoid Arthritis

  2019cites this paper
• Sex Differences in Older Adults' Immune Responses to Seasonal Influenza Vaccination

  2019cites this paper
• Влияние женского феромона на уровень здоровья и функциональное состояние юношей

  2019cites this paper
• TNFα is responsible for the canonical offspring number-size trade-off

  2019cites this paper
• Relevance of Steroid Biosynthesis, Metabolism and Transport in Pathophysiology and Drug Discovery

  2019cites this paper
• Management of Subclinical and Overt Hypothyroidism Following Hemithyroidectomy in Children and Adolescents: A Pilot Study

  2019cites this paper
• Human Papillomavirus Infection and Cancer Risk in Peri- and Postmenopausal Women

  2019cites this paper
• Identification of genes and pathways in human antigen‐presenting cell subsets in response to polio vaccine by bioinformatical analysis

  2019cites this paper
• Feasibility of Localized Metabolomics in the Study of Pancreatic Islets and Diabetes

  2019cites this paper
• A Review of the Impact of Neuter Status on Expression of Inherited Conditions in Dogs

  2019cites this paper
• Intracrine Regulation of Estrogen and Other Sex Steroid Levels in Endometrium and Non-gynecological Tissues; Pathology, Physiology, and Drug Discovery

  2018cites this paper
• Sex differences of inflammation in target organs, induced by intraperitoneal injection of lipopolysaccharide, depend on its dose

  2018cites this paper
• Sex Differences in HIV Infection

  2018cites this paper
• Effects of Estrogen on the Gastrointestinal Tract

  2018cites this paper
• Testosterone is an endogenous regulator of BAFF and splenic B cell number

  2018cites this paper
• Proliferation of B-lymphocytes in inflammatory and hematological diseases

  2018cites this paper
• Sex Differences in HIV Infection: Mystique Versus Machismo

  2018cites this paper
• Gender-related differences in patients with colon cancer resection

  2018cites this paper
• An intracrine view of sex steroids, immunity, and metabolic regulation

  2018cites this paper
• Subcutaneous testosterone-letrozole therapy before and concurrent with neoadjuvant breast chemotherapy: clinical response and therapeutic implications

  2017cites this paper
• Stress differentially affects the systemic and leukocyte estrogen network in common carp

  2017cites this paper
• Interleukin-1 and estrogen protect against disseminating dentoalveolar infections

  2017cites this paper
• The immunomodulatory role of the hypothalamus-pituitary-gonad axis: Proximate mechanism for reproduction-immune trade offs?

  2017cites this paper
• Vitamin D in autoimmune rheumatic diseases: A view inside gender differences

  2017cites this paper
• Indications and outcomes of pediatric keratoplasty in a tertiary eye care center

  2017cites this paper
• T Cell Subpopulations in Healthy Elderly and Lung Cancer Patients: Insights from Cuban Studies

  2017cites this paper
• Protection against Pertussis in Humans Correlates to Elevated Serum Antibodies and Memory B Cells

  2017cites this paper
• Dihydrotestosterone levels at birth associate positively with higher proportions of circulating immature/naïve CD5+ B cells in boys

  2017cites this paper
• Long-term follow-up in primary Sjögren’s syndrome reveals differences in clinical presentation between female and male patients

  2017cites this paper
• Vitamin D : Autoimmunity and Gender.

  2017cites this paper
• HSC extrinsic sex-related and intrinsic autoimmune disease-related human B-cell variation is recapitulated in humanized mice.

  2017cites this paper
• Torque Teno Virus Load—Inverse Association With Antibody-Mediated Rejection After Kidney Transplantation

  2017cites this paper
• The role of dehydroepiandrosterone on functional innate immune responses to acute stress

  2017cites this paper
• MOLECULAR AND CLINICAL SEXUAL DIMORPHISM IN SYSTEMIC AUTOIMMUNITY

  2017cites this paper
• Gender Medicine in Austria

  2017cites this paper