Loss of Heterozygosity and Its Correlation with Expression Profiles in Subclasses of Invasive Breast Cancers

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Cancer Research

• Publication date

  2004-01-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1158/0008-5472.CAN-03-2570PMID 14729609
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2002influential reference
• Single nucleotide polymorphism array analysis of flow-sorted epithelial cells from frozen versus fixed tissues for whole genome analysis of allelic loss in breast cancer.

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• Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications

  2001influential reference
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  2000influential reference
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• Genome-wide search for loss of heterozygosity using laser capture microdissected tissue of breast carcinoma: an implication for mutator phenotype and breast cancer pathogenesis.

  2000influential reference
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  1999cited by this paper
• 17q21-q25 aberrations in breast cancer: combined allelotyping and CGH analysis reveals 5 regions of allelic imbalance among which two correspond to DNA amplification

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• DNA copy number losses at 1p32-pter in monozygotic twins concordant for breast cancer.

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  1999cited by this paper
• Localization of human cadherin genes to chromosome regions exhibiting cancer-related loss of heterozygosity.

  1998cited by this paper
• Distinct somatic genetic changes associated with tumor progression in carriers of BRCA1 and BRCA2 germ-line mutations.

  1997cited by this paper
• Tumour biological features of BRCA1-induced breast and ovarian cancer.

  1997cited by this paper
• Genome-wide search for loss of heterozygosity shows extensive genetic diversity of human breast carcinomas.

  1997influential reference
• Comparative genomic hybridization analysis of breast tumors with predetermined profiles of DNA amplification.

  1997cited by this paper
• Consistent loss of the wild type allele in breast cancers from a family linked to the BRCA2 gene on chromosome 13q12-13.

  1995cited by this paper
• BRCA1 mutations in primary breast and ovarian carcinomas.

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• Genetic basis for p53 overexpression in human breast cancer.

  1991cited by this paper
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  1990cited by this paper
• Allelotype of colorectal carcinomas.

  1989cited by this paper
• Mutations in the p53 gene occur in diverse human tumour types

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• Expression of recessive alleles by chromosomal mechanisms in retinoblastoma

  1983cited by this paper

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