DNA methylation homeostasis in human and mouse development.

No abstract is available for this paper.

• Publication year

  2017

• Venue

  Current Opinion in Genetics and Development

• Publication date

  2017-04-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.gde.2017.02.003PMID 28260631
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Gender Differences in Global but Not Targeted Demethylation in iPSC Reprogramming

  2017cited by this paper
• Naive Human Pluripotent Cells Feature a Methylation Landscape Devoid of Blastocyst or Germline Memory.

  2016cited by this paper
• Hemi-methylated DNA opens a closed conformation of UHRF1 to facilitate its histone recognition

  2016cited by this paper
• Naive Pluripotent Stem Cells Derived Directly from Isolated Cells of the Human Inner Cell Mass

  2016cited by this paper
• DNA methylation dynamics in mouse preimplantation embryos revealed by mass spectrometry

  2016cited by this paper
• De novo DNA methylation drives 5hmC accumulation in mouse zygotes

  2016cited by this paper
• Impairment of DNA Methylation Maintenance Is the Main Cause of Global Demethylation in Naive Embryonic Stem Cells

  2016cited by this paper
• The Germ Cell Fate of Cynomolgus Monkeys Is Specified in the Nascent Amnion.

  2016cited by this paper
• Comparative Principles of DNA Methylation Reprogramming during Human and Mouse In Vitro Primordial Germ Cell Specification

  2016cited by this paper
• Specification and epigenetic programming of the human germ line

  2016cited by this paper
• The DNA methyltransferase DNMT3C protects male germ cells from transposon activity

  2016cited by this paper
• An epigenetic switch ensures transposon repression upon dynamic loss of DNA methylation in embryonic stem cells

  2016cited by this paper
• Global Landscape and Regulatory Principles of DNA Methylation Reprogramming for Germ Cell Specification by Mouse Pluripotent Stem Cells.

  2016cited by this paper
• Isoform Switch of TET1 Regulates DNA Demethylation and Mouse Development.

  2016cited by this paper
• Dissecting the precise role of H3K9 methylation in crosstalk with DNA maintenance methylation in mammals

  2016cited by this paper
• MERVL/Zscan4 Network Activation Results in Transient Genome-wide DNA Demethylation of mESCs

  2016cited by this paper
• Single-cell epigenomics: powerful new methods for understanding gene regulation and cell identity

  2016cited by this paper
• A Surveillance Mechanism Ensures Repair of DNA Lesions during Zygotic Reprogramming

  2016cited by this paper
• Hemi-methylated DNA regulates DNA methylation inheritance through allosteric activation of H3 ubiquitylation by UHRF1

  2016cited by this paper
• Stage-Specific Demethylation in Primordial Germ Cells Safeguards against Precocious Differentiation.

  2016cited by this paper
• The Transcriptome and DNA Methylome Landscapes of Human Primordial Germ Cells.

  2015cited by this paper
• SOX17 Is a Critical Specifier of Human Primordial Germ Cell Fate

  2015cited by this paper
• Human primordial germ cell commitment in vitro associates with a unique PRDM14 expression profile

  2015cited by this paper
• Parallel single-cell sequencing links transcriptional and epigenetic heterogeneity

  2015cited by this paper
• Robust In Vitro Induction of Human Germ Cell Fate from Pluripotent Stem Cells.

  2015cited by this paper
• DNA methylation requires a DNMT1 ubiquitin interacting motif (UIM) and histone ubiquitination

  2015cited by this paper
• Chromatin dynamics and the role of G9a in gene regulation and enhancer silencing during early mouse development

  2015cited by this paper
• DNA Demethylation Dynamics in the Human Prenatal Germline.

  2015cited by this paper
• A Unique Gene Regulatory Network Resets the Human Germline Epigenome for Development

  2015cited by this paper
• Resetting Transcription Factor Control Circuitry toward Ground-State Pluripotency in Human

  2014cited by this paper
• Systematic Identification of Culture Conditions for Induction and Maintenance of Naive Human Pluripotency

  2014cited by this paper
• DNA methylation dynamics of the human preimplantation embryo

  2014cited by this paper
• Reprogramming the Methylome: Erasing Memory and Creating Diversity

  2014cited by this paper
• The DNA methylation landscape of human early embryos

  2014cited by this paper
• Genome-wide Bisulfite Sequencing in Zygotes Identifies Demethylation Targets and Maps the Contribution of TET3 Oxidation

  2014cited by this paper
• Ontogeny of CpG island methylation and specificity of DNMT3 methyltransferases during embryonic development in the mouse

  2014cited by this paper
• Reversing DNA methylation: mechanisms, genomics, and biological functions.

  2014cited by this paper
• Programming and inheritance of parental DNA methylomes in mammals.

  2014cited by this paper
• Tet3 and DNA replication mediate demethylation of both the maternal and paternal genomes in mouse zygotes.

  2014cited by this paper
• DNA methylation dynamics during epigenetic reprogramming in the germline and preimplantation embryos

  2014cited by this paper
• Systematic Identification of Culture Conditions for Induction and Maintenance of Naive Human Pluripotency

  2014cited by this paper
• Active and passive demethylation of male and female pronuclear DNA in the mammalian zygote.

  2014cited by this paper
• FGF Signaling Inhibition in ESCs Drives Rapid Genome-wide Demethylation to the Epigenetic Ground State of Pluripotency

  2013cited by this paper
• Prdm14 promotes germline fate and naive pluripotency by repressing FGF signalling and DNA methylation

  2013cited by this paper
• UHRF1 targets DNMT1 for DNA methylation through cooperative binding of hemi-methylated DNA and methylated H3K9

  2013cited by this paper
• Germline DNA Demethylation Dynamics and Imprint Erasure Through 5-Hydroxymethylcytosine

  2013cited by this paper
• Active demethylation in mouse zygotes involves cytosine deamination and base excision repair

  2013cited by this paper
• Naïve pluripotency is associated with global DNA hypomethylation

  2013cited by this paper
• Dynamics of 5-methylcytosine and 5-hydroxymethylcytosine during germ cell reprogramming

  2013cited by this paper
• Combined deficiency of Tet1 and Tet2 causes epigenetic abnormalities but is compatible with postnatal development.

  2013cited by this paper
• Synergistic Mechanisms of DNA Demethylation during Transition to Ground-State Pluripotency

  2013cited by this paper
• Stage-specific roles for tet1 and tet2 in DNA demethylation in primordial germ cells.

  2013cited by this paper
• Uhrf1-dependent H3K23 ubiquitylation couples maintenance DNA methylation and replication

  2013cited by this paper
• A tripartite transcription factor network regulates primordial germ cell specification in mice

  2013cited by this paper
• Whole-genome bisulfite sequencing of two distinct interconvertible DNA methylomes of mouse embryonic stem cells.

  2013cited by this paper
• High-resolution DNA methylome analysis of primordial germ cells identifies gender-specific reprogramming in mice

  2013cited by this paper
• Pluripotency in the embryo and in culture.

  2012cited by this paper
• The Dynamics of Genome-wide DNA Methylation Reprogramming in Mouse Primordial Germ Cells

  2012cited by this paper
• Global profiling of DNA methylation erasure in mouse primordial germ cells.

  2012cited by this paper
• Replication‐coupled passive DNA demethylation for the erasure of genome imprints in mice

  2012cited by this paper
• Functions of DNA methylation: islands, start sites, gene bodies and beyond

  2012cited by this paper
• A unique regulatory phase of DNA methylation in the early mammalian embryo

  2012cited by this paper
• The Transcriptional and Epigenomic Foundations of Ground State Pluripotency

  2012cited by this paper
• In Embryonic Stem Cells, ZFP57/KAP1 Recognize a Methylated Hexanucleotide to Affect Chromatin and DNA Methylation of Imprinting Control Regions

  2011cited by this paper
• Reprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5-methylcytosine

  2011cited by this paper
• Generation and replication-dependent dilution of 5fC and 5caC during mouse preimplantation development

  2011cited by this paper
• The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes

  2011cited by this paper
• Dynamic CpG island methylation landscape in oocytes and preimplantation embryos

  2011cited by this paper
• 5-Hydroxymethylcytosine in the mammalian zygote is linked with epigenetic reprogramming.

  2011cited by this paper
• Dynamic link of DNA demethylation, DNA strand breaks and repair in mouse zygotes

  2010cited by this paper
• Genome-Wide Reprogramming in the Mouse Germ Line Entails the Base Excision Repair Pathway

  2010cited by this paper
• The multi-domain protein Np95 connects DNA methylation and histone modification

  2009cited by this paper
• Structural basis for recognition of hemi-methylated DNA by the SRA domain of human UHRF1

  2008cited by this paper
• The SRA domain of UHRF1 flips 5-methylcytosine out of the DNA helix

  2008cited by this paper
• Recognition of hemi-methylated DNA by the SRA protein UHRF1 by a base-flipping mechanism

  2008cited by this paper
• The elusive Dnmt1 and its role during early development

  2008cited by this paper
• Maternal and zygotic Dnmt1 are necessary and sufficient for the maintenance of DNA methylation imprints during preimplantation development.

  2008cited by this paper
• Preimplantation expression of the somatic form of Dnmt1 suggests a role in the inheritance of genomic imprints

  2008cited by this paper
• The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNA

  2007cited by this paper
• UHRF1 Plays a Role in Maintaining DNA Methylation in Mammalian Cells

  2007cited by this paper

• Cannabidiol inhibits melanoma progression by regulating PPARγ-TET1 complex-dependent LRSAM1 demethylation.

  2026cites this paper
• DNA methylation mechanisms in the maturing and ageing oocyte

  2025cites this paper
• Accumulation of Epigenetic Noise in the Aging Corneal Epithelium and Its Possible Mechanism

  2025cites this paper
• Role of Stem Cells in Ageing and Age-related Diseases.

  2025cites this paper
• Matrix Stiffness-Mediated DNA Methylation in Endothelial Cells

  2025cites this paper
• Epigenetic dysregulation in recurrent pregnancy loss: the pivotal roles of DNMT and TET enzymes

  2025cites this paper
• LINE-1 retrotransposons mediate cis-acting transcriptional control in human pluripotent stem cells and regulate early brain development

  2025cites this paper
• High resolution multi-scale profiling of embryonic germ cell-like cell derivation reveals pluripotent state transitions in humans.

  2025cites this paper
• Metabolic enzymes aldo-2 and pdhb-1 as potential epigenetic regulators during C. elegans embryogenesis

  2024cites this paper
• Epigenetic mechanisms linking early-life adversities and mental health.

  2024cites this paper
• Adverse effects of bisphenol A and its analogues on male fertility: An epigenetic perspective.

  2024cites this paper
• Escape from X-chromosome inactivation and sex differences in Alzheimer’s disease

  2024cites this paper
• The identification and classification of candidate genes during the zygotic genome activation in the mammals.

  2024cites this paper
• DNMT3b-mediated CpA methylation facilitates REST binding and gene silencing and exacerbates hippocampal demyelination in diabetic mice

  2024cites this paper
• Copper Oxide Nanoparticles Impair Mouse Preimplantation Embryonic Development through Disruption of Mitophagy-Mediated Metabolism

  2024cites this paper
• Evaluating the connection between diet quality, EpiNutrient intake and epigenetic age: an observational study.

  2024cites this paper
• The Role of DNMT Methyltransferases and TET Dioxygenases in the Maintenance of the DNA Methylation Level

  2024cites this paper
• Transcription of Endogenous Retroviruses: Broad and Precise Mechanisms of Control

  2024cites this paper
• Kick-starting the zygotic genome: licensors, specifiers, and beyond

  2024cites this paper
• Optimized Protocol for the Regulation of DNA Methylation and Gene Expression Using Modified dCas9-SunTag Platforms.

  2024cites this paper
• Remembering foods and foes: emerging principles of transcriptional memory

  2023cites this paper
• From cellular to fear memory: An epigenetic toolbox to remember.

  2023cites this paper
• Engineered deaminases as a key component of DNA and RNA editing tools

  2023cites this paper
• MAP4K4 is involved in the neuronal development of retinal photoreceptors.

  2023cites this paper
• RNautophagic regulation of DNMT3a‐dependent DNA methylation by Linc00942 enhances chemoresistance in gastric cancer

  2023cites this paper
• Long noncoding RNA (lncRNA) H19: An essential developmental regulator with expanding roles in cancer, stem cell differentiation, and metabolic diseases

  2023cites this paper
• Single-molecule footprinting identifies context-dependent regulation of enhancers by DNA methylation.

  2023cites this paper
• Transgenerational epigenetic control of constitutive heterochromatin, transposons, and centromeres.

  2023cites this paper
• Epigenetic biomarkers for animal welfare monitoring

  2023cites this paper
• α-Kleisin subunit of cohesin preserves the genome integrity of embryonic stem cells

  2022cites this paper
• Epigenetics as “conductor” in “orchestra” of pluripotent states

  2022cites this paper
• Clinical and Prognostic Values of DNMT3B Expression in Hepatocellular Carcinoma

  2022influential citation
• Single molecule multi-omics reveals context-dependent regulation of enhancers by DNA methylation

  2022influential citation
• DNA Methylation Imputation Across Platforms.

  2022cites this paper
• ImmuMethy, a database of DNA methylation plasticity at a single cytosine resolution in human blood and immune cells

  2022cites this paper
• Heterozygous loss of Zbtb38 leads to early embryonic lethality via the suppression of Nanog and Sox2 expression

  2022cites this paper
• Dynamic nucleosome organization after fertilization reveals regulatory factors for mouse zygotic genome activation

  2022cites this paper
• Expression of epigenetic pathway related genes in association with PD-L1, ER/PgR and MLH1 in endometrial carcinoma

  2022cites this paper
• The chromosomal protein SMCHD1 regulates DNA methylation and the 2c-like state of embryonic stem cells by antagonizing TET proteins

  2021cites this paper
• Inducible Uniparental Chromosome Disomy to Probe Genomic Imprinting at Single-cell Level in Brain and Beyond.

  2021cites this paper
• Epigenetic regulation of inflammation by CxxC domain‐containing proteins *

  2021cites this paper
• Uterine deficiency of Dnmt3b impairs decidualization and causes consequent embryo implantation defects

  2021cites this paper
• Therapeutic Targeting of Cancer: Epigenetic Homeostasis

  2021cites this paper
• Roles of TET and TDG in DNA demethylation in proliferating and non-proliferating immune cells

  2021cites this paper
• Chromatin accessibility dynamics during cell fate reprogramming

  2021cites this paper
• DNA methylation changes induced by BDE-209 are related to DNA damage response and germ cell development in GC-2spd.

  2021cites this paper
• Purification of TET Proteins.

  2021cites this paper
• The regulation mechanisms and the Lamarckian inheritance property of DNA methylation in animals

  2021cites this paper
• Resveratrol inhibits the tumor migration and invasion by upregulating TET1 and reducing TIMP2/3 methylation in prostate carcinoma cells

  2020cites this paper
• Phylogenic determinants of cardiovascular frailty, focus on hemodynamics and arterial smooth muscle cells.

  2020cites this paper
• DNA methylation-driven EMT is a common mechanism of resistance to various therapeutic agents in cancer

  2020cites this paper
• DNA methylation editing by CRISPR-guided excision of 5-methylcytosine.

  2020cites this paper
• IMPLICON: an ultra-deep sequencing method to uncover DNA methylation at imprinted regions

  2020cites this paper
• Prenatal bisphenol-A exposure altered exploratory and anxiety-like behaviour and induced non-monotonic, sex-specific changes in the cortical expression of CYP19A1, BDNF and intracellular signaling proteins in F1 rats.

  2020cites this paper
• Electronic Equivalent of Consciousness with Elementary Mental Process Model

  2020cites this paper
• CUE: CpG impUtation Ensemble for DNA Methylation Levels Across the Human Methylation450 (HM450) and EPIC (HM850) BeadChip Platforms

  2020cites this paper
• DNA methylation and the core pluripotency network.

  2020cites this paper
• TET1-DNA Hydroxymethylation Mediated Oligodendrocyte Homeostasis is Required for CNS Myelination and Remyelination

  2020cites this paper
• Insights into epigenetic patterns in mammalian early embryos

  2020cites this paper
• Organization of the Pluripotent Genome.

  2020cites this paper
• BPA's transgenerational disturbance to transcription of ovarian steroidogenic genes in rare minnow Gobiocypris rarus via DNA and histone methylation.

  2020cites this paper
• Chromatin plasticity in pluripotent and cancer stem cells

  2020cites this paper
• Keeping your options open: insights from Dppa2/4 into how epigenetic priming factors promote cell plasticity

  2020cites this paper
• Reprogramming of DNA methylation at NEUROD2-bound sequences during cortical neuron differentiation

  2019cites this paper
• Epigenetic Regulation of Transition Among Different Pluripotent States: Concise Review

  2019cites this paper
• Stability and Lability of Parental Methylation Imprints in Development and Disease

  2019cites this paper
• TET1-mediated Oligodendrocyte Homeostasis Regulates Myelination and Synaptic Functions

  2019cites this paper
• Strand-specific single-cell methylomics reveals distinct modes of DNA demethylation dynamics during early mammalian development

  2019cites this paper
• The influence of DNA methylation on monoallelic expression

  2019cites this paper
• DNA Methylation and Histone H1 Jointly Repress Transposable Elements and Aberrant Intragenic Transcripts.

  2019cites this paper
• Epigenetic remodelling licences adult cholangiocytes for organoid formation and liver regeneration

  2019cites this paper
• Ten-eleven translocation 1 mediated-DNA hydroxymethylation is required for myelination and remyelination in the mouse brain

  2019cites this paper
• DNA methylation dynamics at transposable elements in mammals.

  2019cites this paper
• Does epigenetic ‘memory’ of early-life stress predispose to chronic pain in later life? A potential role for the stress regulator FKBP5

  2019cites this paper
• B-vitamins & one-carbon metabolism

  2019cites this paper
• Early-Life Adjustment of Epigenetic Aging Clock

  2019cites this paper
• Single‐base methylome profiling of the giant kelp Saccharina japonica reveals significant differences in DNA methylation to microalgae and plants

  2019cites this paper
• Joint profiling of DNA methylation and chromatin architecture in single cells

  2019cites this paper
• Concise Review: Epigenetic Regulation of Transition among Different Pluripotent States.

  2019cites this paper
• Epigenetic aberrations in human pluripotent stem cells

  2019cites this paper
• DNA methylation and histone H1 cooperatively repress transposable elements and aberrant intragenic transcripts

  2019cites this paper
• Endo-siRNAs regulate early embryonic development by inhibiting transcription of long terminal repeat sequence in pig†

  2019cites this paper
• DNA Methylation Regulates Corneal Epithelial Wound Healing by Targeting miR-200a and CDKN2B.

  2019cites this paper
• Transcriptional Heterogeneity in Naive and Primed Human Pluripotent Stem Cells at Single-Cell Resolution

  2019cites this paper
• On the epigenetic ageing clock in humans

  2019cites this paper
• Chromatin remodeling in bovine embryos indicates species-specific regulation of genome activation

  2019cites this paper
• Population Epigenomics: Advancing Understanding of Phenotypic Plasticity, Acclimation, Adaptation and Diseases

  2018cites this paper
• Dynamics of the epigenetic landscape during the maternal-to-zygotic transition

  2018cites this paper
• LPS-induces IL-6 and IL-8 gene expression in bovine endometrial cells "through DNA methylation".

  2018cites this paper
• Developmental programming of aging trajectory.

  2018cites this paper
• Genome-Scale Oscillations in DNA Methylation during Exit from Pluripotency

  2018cites this paper
• Abnormal folate metabolism causes age‐, sex‐ and parent‐of‐origin‐specific haematological defects in mice

  2018cites this paper
• The Epigenetics of Early Life Adversity: Current Limitations and Possible Solutions.

  2018cites this paper
• Eicosapentaenoic acid induces DNA demethylation in carcinoma cells through a TET1‐dependent mechanism

  2018cites this paper
• Editing of DNA Methylation Using dCas9-Peptide Repeat and scFv-TET1 Catalytic Domain Fusions.

  2018cites this paper
• Developmental Functions of the Dynamic DNA Methylome and Hydroxymethylome in the Mouse and Zebrafish: Similarities and Differences

  2018influential citation
• Environmental effects on chromatin repression at imprinted genes and endogenous retroviruses.

  2018cites this paper
• The role of the X chromosome in embryonic and postnatal growth

  2018cites this paper
• Simultaneous profiling of DNA methylation and chromatin architecture in mixed populations and in single cells

  2018cites this paper
• Can Reprogramming of Overall Epigenetic Memory and Specific Parental Genomic Imprinting Memory within Donor Cell-Inherited Nuclear Genome be a Major Hindrance for the Somatic Cell Cloning of Mammals? – A Review

  2018influential citation