MPK6, sphinganine and the LCB2a gene from serine palmitoyltransferase are required in the signaling pathway that mediates cell death induced by long chain bases in Arabidopsis.

No abstract is available for this paper.

• Publication year

  2011

• Venue

  New Phytologist

• Publication date

  2011-09-01

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1111/j.1469-8137.2011.03727.xPMID 21534970
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Lipid Signaling

  2019cited by this paper
• Plant sphingolipids: decoding the enigma of the Sphinx.

  2010cited by this paper
• Pseudomonas syringae infection triggers de novo synthesis of phytosphingosine from sphinganine in Arabidopsis thaliana

  2010cited by this paper
• Nuclear calcium controls the apoptotic-like cell death induced by d-erythro-sphinganine in tobacco cells.

  2010influential reference
• Accumulation of chlorophyll catabolites photosensitizes the hypersensitive response elicited by Pseudomonas syringae in Arabidopsis.

  2010cited by this paper
• The SPTLC3 Subunit of Serine Palmitoyltransferase Generates Short Chain Sphingoid Bases*

  2009cited by this paper
• Phospholipase Dα1 and Phosphatidic Acid Regulate NADPH Oxidase Activity and Production of Reactive Oxygen Species in ABA-Mediated Stomatal Closure in Arabidopsis[C][W][OA]

  2009cited by this paper
• Serine palmitoyltransferase, the first step enzyme in sphingolipid biosynthesis, is involved in nonhost resistance.

  2009influential reference
• Plant Sphingolipids: Structure, Synthesis and Function

  2009influential reference
• A major role of the MEKK1-MKK1/2-MPK4 pathway in ROS signalling.

  2009cited by this paper
• Arabidopsis MPK6 is involved in cell division plane control during early root development, and localizes to the pre-prophase band, phragmoplast, trans-Golgi network and plasma membrane.

  2009cited by this paper
• Mitogen-Activated Protein Kinases 3 and 6 Are Required for Full Priming of Stress Responses in Arabidopsis thaliana[W][OA]

  2009cited by this paper
• MAPK target networks in Arabidopsis thaliana revealed using functional protein microarrays.

  2009cited by this paper
• MAP KINASE PHOSPHATASE1 and PROTEIN TYROSINE PHOSPHATASE1 Are Repressors of Salicylic Acid Synthesis and SNC1-Mediated Responses in Arabidopsis[C][W]

  2009cited by this paper
• Arabidopsis MAPKs: a complex signalling network involved in multiple biological processes.

  2008cited by this paper
• A fungal-responsive MAPK cascade regulates phytoalexin biosynthesis in Arabidopsis

  2008cited by this paper
• Functional Characterization of a Higher Plant Sphingolipid D 4-Desaturase: Defining the Role of Sphingosine and Sphingosine-1-Phosphate in Arabidopsis

  2008cited by this paper
• Loss-of-function mutations and inducible RNAi suppression of Arabidopsis LCB2 genes reveal the critical role of sphingolipids in gametophytic and sporophytic cell viability.

  2008influential reference
• Principles of bioactive lipid signalling: lessons from sphingolipids

  2008cited by this paper
• Functional Characterization of a Higher Plant Sphingolipid Δ4-Desaturase: Defining the Role of Sphingosine and Sphingosine-1-Phosphate in Arabidopsis1[W][OA]

  2008cited by this paper
• An Inositolphosphorylceramide Synthase Is Involved in Regulation of Plant Programmed Cell Death Associated with Defense in Arabidopsis[C][W]

  2008influential reference
• Involvement of sphingosine kinase in plant cell signalling.

  2008influential reference
• Sphingolipid Long-Chain Base Hydroxylation Is Important for Growth and Regulation of Sphingolipid Content and Composition in Arabidopsis[W]

  2008influential reference
• Stomatal Development and Patterning Are Regulated by Environmentally Responsive Mitogen-Activated Protein Kinases in Arabidopsis[W]

  2007cited by this paper
• Tracheary element differentiation.

  2007cited by this paper
• Arabidopsis Mutants Lacking Long Chain Base Phosphate Lyase Are Fumonisin-sensitive and Accumulate Trihydroxy-18:1 Long Chain Base Phosphate*

  2007cited by this paper
• Mechanical Stress Induces Biotic and Abiotic Stress Responses via a Novel cis-Element

  2007cited by this paper
• Guard cell-specific inhibition of Arabidopsis MPK3 expression causes abnormal stomatal responses to abscisic acid and hydrogen peroxide.

  2007cited by this paper
• Involvement of sphingoid bases in mediating reactive oxygen intermediate production and programmed cell death in Arabidopsis

  2007influential reference
• Chloroplast-generated reactive oxygen species are involved in hypersensitive response-like cell death mediated by a mitogen-activated protein kinase cascade.

  2007cited by this paper
• Rapid measurement of sphingolipids from Arabidopsis thaliana by reversed-phase high-performance liquid chromatography coupled to electrospray ionization tandem mass spectrometry.

  2007cited by this paper
• Mutational evidence that the Arabidopsis MAP kinase MPK6 is involved in anther, inflorescence, and embryo development.

  2007cited by this paper
• The Essential Nature of Sphingolipids in Plants as Revealed by the Functional Identification and Characterization of the Arabidopsis LCB1 Subunit of Serine Palmitoyltransferase[W]

  2006cited by this paper
• Activation of Ntf4, a Tobacco Mitogen-Activated Protein Kinase, during Plant Defense Response and Its Involvement in Hypersensitive Response-Like Cell Death1

  2006cited by this paper
• Cell death in seedlings of the interspecific hybrid of Nicotiana gossei and N. tabacum; possible role of knob-like bodies formed on tonoplast in vacuolar-collapse-mediated cell death

  2006cited by this paper
• Separation and Identification of Major Plant Sphingolipid Classes from Leaves*

  2006cited by this paper
• Ceramides induce programmed cell death in Arabidopsis cells in a calcium-dependent manner

  2005cited by this paper
• Autophagy regulates programmed cell death during the plant innate immune response.

  2005cited by this paper
• SphK1 and SphK2, Sphingosine Kinase Isoenzymes with Opposing Functions in Sphingolipid Metabolism*

  2005influential reference
• Arabidopsis Sphingosine Kinase and the Effects of Phytosphingosine-1-Phosphate on Stomatal Aperture1[w]

  2005influential reference
• Arabidopsis ACCELERATED CELL DEATH2 Modulates Programmed Cell Death[W]

  2005cited by this paper
• Vacuolar Processing Enzyme Is Essential for Mycotoxin-induced Cell Death in Arabidopsis thaliana*

  2005cited by this paper
• A Sphingolipid Elicitor-Inducible Mitogen-Activated Protein Kinase Is Regulated by the Small GTPase OsRac1 and Heterotrimeric G-Protein in Rice1[w]

  2005cited by this paper
• Signalling functions for sphingolipid long-chain bases in Saccharomyces cerevisiae.

  2005cited by this paper
• The mitochondrion--an organelle commonly involved in programmed cell death in Arabidopsis thaliana.

  2004cited by this paper
• Phosphorylation of 1-Aminocyclopropane-1-Carboxylic Acid Synthase by MPK6, a Stress-Responsive Mitogen-Activated Protein Kinase, Induces Ethylene Biosynthesis in Arabidopsisw⃞

  2004cited by this paper
• Silencing of the Mitogen-Activated Protein Kinase MPK6 Compromises Disease Resistance in Arabidopsis

  2004influential reference
• The Arabidopsis Putative G Protein–Coupled Receptor GCR1 Interacts with the G Protein α Subunit GPA1 and Regulates Abscisic Acid Signaling

  2004cited by this paper
• Lipid signaling.

  2004cited by this paper
• The enigma of the sphinx

  2003influential reference
• Sphingolipid signalling in Arabidopsis guard cells involves heterotrimeric G proteins

  2003cited by this paper
• Quantitative Nature of Arabidopsis Responses during Compatible and Incompatible Interactions with the Bacterial Pathogen Pseudomonas syringae Online version contains Web-only data. Article, publication date, and citation information can be found at www.plantcell.org/cgi/doi/10.1105/tpc.007591.

  2003cited by this paper
• Ceramides modulate programmed cell death in plants.

  2003cited by this paper
• Mitogen-activated protein kinases.

  2002cited by this paper
• hrp genes of Erwinia chrysanthemi 3937 are important virulence factors.

  2002cited by this paper
• Knockout of Arabidopsis accelerated-cell-death11 encoding a sphingosine transfer protein causes activation of programmed cell death and defense.

  2002cited by this paper
• Distinct regulation of salinity and genotoxic stress responses by Arabidopsis MAP kinase phosphatase 1

  2002cited by this paper
• MAP kinase signalling cascade in Arabidopsis innate immunity

  2002cited by this paper
• Mutations in the Yeast LCB1 and LCB2Genes, Including Those Corresponding to the Hereditary Sensory Neuropathy Type I Mutations, Dominantly Inactivate Serine Palmitoyltransferase*

  2002cited by this paper
• Cell Death Mediated by MAPK Is Associated with Hydrogen Peroxide Production in Arabidopsis *

  2002cited by this paper
• Harpin induces activation of the Arabidopsis mitogen-activated protein kinases AtMPK4 and AtMPK6.

  2001cited by this paper
• Mitogen-activated protein kinase phosphatase is required for genotoxic stress relief in Arabidopsis.

  2001cited by this paper
• Sphingolipid metabolism: roles in signal transduction and disruption by fumonisins.

  2001cited by this paper
• Drought-induced guard cell signal transduction involves sphingosine-1-phosphate

  2001cited by this paper
• Guard cell abscisic acid signalling and engineering drought hardiness in plants

  2001cited by this paper
• Simulation of Fungal-Mediated Cell Death by Fumonisin B1 and Selection of Fumonisin B1–Resistant (fbr) Arabidopsis Mutants

  2000cited by this paper
• Fumonisin B1–Induced Cell Death in Arabidopsis Protoplasts Requires Jasmonate-, Ethylene-, and Salicylate-Dependent Signaling Pathways

  2000cited by this paper
• Multiple levels of tobacco WIPK activation during the induction of cell death by fungal elicitins.

  2000cited by this paper
• Activation of mitogen-activated protein kinase by fumonisin B(1) stimulates cPLA(2) phosphorylation, the arachidonic acid cascade and cAMP production.

  1999influential reference
• Activation of the Tobacco SIP Kinase by Both a Cell Wall–Derived Carbohydrate Elicitor and Purified Proteinaceous Elicitins from Phytophthora spp

  1998cited by this paper
• Programmed cell death: a way of life for plants.

  1996cited by this paper
• Activation of mitogen-activated protein kinase by the carcinogenic mycotoxin fumonisin B1.

  1996influential reference
• H2O2 from the oxidative burst orchestrates the plant hypersensitive disease resistance response.

  1994cited by this paper
• Inhibition of sphingolipid biosynthesis by fumonisins. Implications for diseases associated with Fusarium moniliforme.

  1991cited by this paper

• Fungal Sphingolipids: Biosynthesis Pathways, Structural Features and Biological Functions.

  2026cites this paper
• Sphingolipid long chain bases as mediators of cell death in olive fruit abscission

  2025influential citation
• Role of cuticle, sterols, sphingolipids, and glycerolipids in plant defense.

  2025cites this paper
• Metabolomic and Physiological Analysis of Blueberry (Vaccinium spp.) in Response to Ericoid Mycorrhizal Fungi (Oidiodendron maius H14)

  2025cites this paper
• Understanding lipid-mediated defense mechanisms in plant responses to abiotic stress

  2025cites this paper
• Lesion mimic gene HLM1 positively regulates cell death and disease resistance in rice

  2025cites this paper
• Chemical composition and bioinsecticidal activity of bioinputs produced by Saccharopolyspora spinosa

  2025cites this paper
• Non-targeted metabolomics reveals fatty acid and associated pathways driving resistance to whitefly and tomato leafminer in wild tomato accessions

  2025cites this paper
• Sphingolipid metabolism and signaling in plant stress responses and crop improvement.

  2025cites this paper
• Sphingolipid homeostasis--how do cells know when enough is enough? Implications for plant pathogen responses.

  2024cites this paper
• Exploring lipid signaling in plant physiology: From cellular membranes to environmental adaptation.

  2024cites this paper
• Natural Algaecide Sphingosines Identified in Hybrid Straw Decomposition Driven by White‐Rot Fungi

  2023cites this paper
• Phosphorylation of the LCB1 subunit of Arabidopsis serine palmitoyltransferase stimulates its activity and modulates sphingolipid biosynthesis.

  2023cites this paper
• Sphingolipid Long-Chain Base Signaling in Compatible and Non-Compatible Plant–Pathogen Interactions in Arabidopsis

  2023cites this paper
• Proteomics analysis reveals three potential cacao target that interacts with Moniliophthora perniciosa NEP during witches broom disease

  2023cites this paper
• New Paradigms in Brassinosteroids, Strigolactones, Sphingolipids, and Nitric Oxide Interaction in the Control of Lateral and Adventitious Root Formation

  2023cites this paper
• Combination of transcriptomic, proteomic and degradomic profiling reveals common and distinct patterns of pathogen-induced cell death in maize

  2022cites this paper
• Extracellular ATP targets Arabidopsis RIBONUCLEASE 1 to suppress mycotoxin stress‐induced cell death

  2022cites this paper
• Sphingolipids in plant immunity

  2022influential citation
• Sphingolipids are involved in insect egg-induced cell death in Arabidopsis.

  2022cites this paper
• Growth and metabolism of dark septate endophytes and their stimulatory effects on plant growth.

  2022cites this paper
• Nitrated Fatty-Acids Distribution in Storage Biomolecules during Arabidopsis thaliana Development

  2022cites this paper
• The Two Classes of Ceramide Synthases Play Different Roles in Plant Immunity and Cell Death

  2022cites this paper
• Plant defence mechanisms against mycotoxin fumonisin B1.

  2021cites this paper
• Biosynthesis and Functions of Very-Long-Chain Fatty Acids in the Responses of Plants to Abiotic and Biotic Stresses

  2021cites this paper
• Phenotypic and transcriptomic analyses reveal major differences between apple and pear scab nonhost resistance

  2021influential citation
• Effects of MPK3 and MPK6 kinases on the chloroplast architecture and function induced by cold acclimation in Arabidopsis

  2021cites this paper
• Serum metabolomics in chickens infected with Cryptosporidium baileyi

  2021cites this paper
• Sphingolipids are involved in Pieris brassicae egg-induced cell death in Arabidopsis thaliana

  2021cites this paper
• Sphingolipids in foodstuff: Compositions, distribution, digestion, metabolism and health effects - A comprehensive review.

  2021cites this paper
• Sphingolipid metabolism, transport, and functions in plants: Recent progress and future perspectives

  2021cites this paper
• Host Resistance Signaling Network System to Multiple Stresses

  2021cites this paper
• Plasma and Vacuolar Membrane Sphingolipidomes: Composition and Insights on The Role of Main Molecular Species.

  2021cites this paper
• Comparative Secretome and Functional Analyses Reveal Glycoside Hydrolase Family 30 and Cysteine Peptidase as Virulence Determinants in the Pinewood Nematode Bursaphelenchus xylophilus

  2021cites this paper
• Sphingolipid-Induced Programmed Cell Death is a Salicylic Acid and EDS1-Dependent Phenotype in Arabidopsis Fatty Acid Hydroxylase (Fah1, Fah2) and Ceramide Synthase (Loh2) Triple Mutants

  2021cites this paper
• Metabolic profiling of DREB-overexpressing transgenic wheat seeds by liquid chromatography–mass spectrometry

  2020cites this paper
• Title : Phosphorylation of LCB 1 subunit of serine palmitoyltransferase stimulates its 1 activity and modulates sphingolipid biosynthesis in Arabidopsis 2 3 Running title : Phosphorylation of LCB 1 subunit activates serine palmitoyltransferase

  2020cites this paper
• Sphinganine-Analog Mycotoxins (SAMs): Chemical Structures, Bioactivities, and Genetic Controls

  2020cites this paper
• Sphingolipids in plants: a guidebook on their function in membrane architecture, cellular processes, and environmental or developmental responses

  2020cites this paper
• Fumonisin B1: A Tool for Exploring the Multiple Functions of Sphingolipids in Plants

  2020cites this paper
• Sphingolipid Effects on the Plasma Membrane Produced by Addition of Fumonisin B1 to Maize Embryos

  2020cites this paper
• Organized Disassembly of Photosynthesis During Programmed Cell Death Mediated By Long Chain Bases

  2020cites this paper
• A Plant Immune Receptor Degraded by Selective Autophagy.

  2019cites this paper
• Overexpression of FBR41 enhances resistance to sphinganine analog mycotoxin‐induced cell death and Alternaria stem canker in tomato

  2019cites this paper
• Sphingolipid-induced cell death in Arabidopsis is negatively regulated by the papain-like cysteine protease RD21.

  2019cites this paper
• Elevated Levels of Phosphorylated Sphingobases Do Not Antagonize Sphingobase- or Fumonisin B1-Induced Plant Cell Death.

  2019cites this paper
• Disruption of Arabidopsis neutral ceramidases 1 and 2 results in specific sphingolipid imbalances triggering different phytohormone-dependent plant cell death programs.

  2019cites this paper
• Sphingolipids: towards an integrated view of metabolism during the plant stress response

  2019cites this paper
• Sphingolipid Distribution, Content and Gene Expression during Olive-Fruit Development and Ripening

  2018influential citation
• Modulation of sphingolipid long-chain base composition and gene expression during early olive-fruit development, and putative role of brassinosteroid.

  2018cites this paper
• Emerging Roles of Sphingolipid Signaling in Plant Response to Biotic and Abiotic Stresses.

  2018cites this paper
• Sphingosine kinase AtSPHK1 functions in fumonisin B1-triggered cell death in Arabidopsis.

  2017cites this paper
• Association mapping for traits related to nitrogen use efficiency in tropical maize lines under field conditions

  2017cites this paper
• Long-chain base kinase1 affects freezing tolerance in Arabidopsis thaliana.

  2017cites this paper
• Synthesis and degradation of long-chain base phosphates affect fumonisin B1-induced cell death in Arabidopsis thaliana

  2017cites this paper
• Genome-wide Association Analysis Tracks Bacterial Leaf Blight Resistance Loci In Rice Diverse Germplasm

  2017cites this paper
• How Very-Long-Chain Fatty Acids Could Signal Stressful Conditions in Plants?

  2016cites this paper
• Molecular Characterization of Rice OsLCB2a1 Gene and Functional Analysis of its Role in Insect Resistance

  2016cites this paper
• Lipid signalling in plant responses to abiotic stress.

  2016cites this paper
• Molecular characterization and targeted quantitative profiling of the sphingolipidome in rice.

  2016cites this paper
• Plant Sphingolipid Metabolism and Function.

  2016cites this paper
• 18. Plant Lipidomics

  2016cites this paper
• Calcium Sensors as Key Hubs in Plant Responses to Biotic and Abiotic Stresses

  2016cites this paper
• Lipids in Plant and Algae Development

  2016cites this paper
• Toxin distribution and sphingoid base imbalances in Fusarium verticillioides-infected and fumonisin B1-watered maize seedlings.

  2016cites this paper
• A review of redox signaling and the control of MAP kinase pathway in plants

  2016cites this paper
• ORM Expression Alters Sphingolipid Homeostasis and Differentially Affects Ceramide Synthase Activity1[OPEN]

  2016cites this paper
• The sphingolipid biosynthetic enzyme Sphingolipid delta8 desaturase is important for chilling resistance of tomato

  2016cites this paper
• Calcium- and Nitric Oxide-Dependent Nuclear Accumulation of Cytosolic Glyceraldehyde-3-Phosphate Dehydrogenase in Response to Long Chain Bases in Tobacco BY-2 Cells.

  2016cites this paper
• Orosomucoid Proteins Interact with the Small Subunit of Serine Palmitoyltransferase and Contribute to Sphingolipid Homeostasis and Stress Responses in Arabidopsis[OPEN]

  2016cites this paper
• Plant sphingolipids: Their importance in cellular organization and adaption

  2016cites this paper
• Out for a Walk Along the Secretory Pathway During Programmed Cell Death

  2015cites this paper
• Long-chain bases, phosphatidic acid, MAPKs, and reactive oxygen species as nodal signal transducers in stress responses in Arabidopsis

  2015influential citation
• Overexpression of Ceramide Synthase in Arabidopsis 1 Running Head : Overexpression of Ceramide Synthase in Arabidopsis

  2015cites this paper
• Overexpression of BAX INHIBITOR-1 Links Plasma Membrane Microdomain Proteins to Stress1[OPEN]

  2015cites this paper
• Long-chain bases and their phosphorylated derivatives differentially regulate cryptogein-induced production of reactive oxygen species in tobacco (Nicotiana tabacum) BY-2 cells.

  2015cites this paper
• Overexpression of Arabidopsis Ceramide Synthases Differentially Affects Growth, Sphingolipid Metabolism, Programmed Cell Death, and Mycotoxin Resistance1[OPEN]

  2015cites this paper
• Modifications of Sphingolipid Content Affect Tolerance to Hemibiotrophic and Necrotrophic Pathogens by Modulating Plant Defense Responses in Arabidopsis1[OPEN]

  2015cites this paper
• Deciphering the link between salicylic acid signaling and sphingolipid metabolism

  2015cites this paper
• Plant lipid environment and membrane enzymes: the case of the plasma membrane H+-ATPase

  2015cites this paper
• To die or not to die? Lessons from lesion mimic mutants

  2015cites this paper
• A novel function for Arabidopsis CYCLASE 1 in programmed cell death revealed by iTRAQ analysis of extracellular matrix proteins *

  2015cites this paper
• A Novel Function for Arabidopsis CYCLASE1 in Programmed Cell Death Revealed by Isobaric Tags for Relative and Absolute Quantitation (iTRAQ) Analysis of Extracellular Matrix Proteins

  2015cites this paper
• Sphingolipid metabolism is strikingly different between pollen and leaf in Arabidopsis as revealed by compositional and gene expression profiling.

  2015cites this paper
• Overexpression of BI-1 enhances tolerance to stress-induced cell death in plant cells, although

  2015cites this paper
• The Arabidopsis ceramidase AtACER functions in disease resistance and salt tolerance.

  2015cites this paper
• Investigation of Pathways for Complex Sphingolipid Biosynthesis in Arabidopsis thaliana (L.) Heynh

  2015influential citation
• Misexpression of the Niemann-Pick disease type C1 (NPC1)-like protein in Arabidopsis causes sphingolipid accumulation and reproductive defects

  2015cites this paper
• A systematic simulation of the effect of salicylic acid on sphingolipid metabolism

  2014cites this paper
• Functional analysis of Arabidopsis immune-related MAPKs uncovers a role for MPK3 as negative regulator of inducible defences

  2014cites this paper
• Molecular characterization of rice sphingosine-1-phosphate lyase gene OsSPL1 and functional analysis of its role in disease resistance response

  2014influential citation
• Long-chain base phosphates modulate pollen tube growth via channel-mediated influx of calcium.

  2014cites this paper
• Comparative plant sphingolipidomic reveals specific lipids in seeds and oil.

  2014cites this paper
• Roles of lipids as signaling molecules and mitigators during stress response in plants.

  2014cites this paper
• Inhibition of very long acyl chain sphingolipid synthesis modifies membrane dynamics during plant cytokinesis.

  2014cites this paper
• Expression of the Bacterial Type III Effector DspA/E in Saccharomyces cerevisiae Down-regulates the Sphingolipid Biosynthetic Pathway Leading to Growth Arrest*

  2014cites this paper
• Loss of Ceramide Kinase in Arabidopsis Impairs Defenses and Promotes Ceramide Accumulation and Mitochondrial H2O2 Bursts[C][W]

  2014cites this paper
• Fumonisinas –Síntesis y función en la interacción Fusarium verticillioides-maíz

  2014cites this paper
• Relationships between calcium and sphingolipid-dependent signalling pathways during the early steps of plant-pathogen interactions.

  2013cites this paper
• Plant sphingolipids: function follows form.

  2013cites this paper