Running exercise alleviates trabecular bone loss and osteopenia in hemizygous β-globin knockout thalassemic mice.

No abstract is available for this paper.

• Publication year

  2014

• Venue

  American Journal of Physiology. Endocrinology and Metabolism

• Publication date

  2014-06-15

• Fields of study

  Medicine

• Identifiers
  DOI 10.1152/ajpendo.00111.2014PMID 24780610
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• Oxidative stress stimulates apoptosis and activates NF-kappaB in osteoblastic cells via a PKCbeta/p66shc signaling cascade: counter regulation by estrogens or androgens.

  2010cited by this paper
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  2010cited by this paper
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  2009cited by this paper
• Imbalanced globin chain synthesis determines erythroid cell pathology in thalassemic mice

  2009cited by this paper
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  2009cited by this paper
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  2009cited by this paper
• Skeletal remodeling in health and disease

  2007cited by this paper
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  2007cited by this paper
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  2007cited by this paper
• The hematological etiology of osteoporosis.

  2006cited by this paper
• Osteocytes subjected to pulsating fluid flow regulate osteoblast proliferation and differentiation.

  2006cited by this paper
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  2005cited by this paper
• A humanized mouse model for a common beta0-thalassemia mutation.

  2005cited by this paper
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  2004cited by this paper
• Bone histomorphometry in children and adolescents with beta-thalassemia disease: iron-associated focal osteomalacia.

  2003cited by this paper
• Studies of local bone remodeling. The calvarial injection assay.

  2003cited by this paper
• Abnormalities in Bone Mineral Density and Bone Histology in Thalassemia

  2003influential reference
• High-impact exercise strengthens bone in osteopenic ovariectomized rats with the same outcome as Sham rats.

  2003cited by this paper
• Insulin‐Like Growth Factor I Is Required for the Anabolic Actions of Parathyroid Hormone on Mouse Bone

  2002cited by this paper
• Effect of exercise training and detraining on bone mineral density in postmenopausal women with osteoporosis

  2001cited by this paper
• Skeletal muscle capillarity and angiogenic mRNA levels after exercise training in normoxia and chronic hypoxia.

  2001cited by this paper
• Disruption of the fibroblast growth factor-2 gene results in decreased bone mass and bone formation.

  2000cited by this paper
• Serum Levels of Tumor Necrosis Factor-alpha, Interleukin-1, and Interferon-gamma in beta-Thalassemia/HbE and Their Clinical Significance

  1999cited by this paper
• Differential effect of treadmill exercise on three cancellous bone sites in the young growing rat.

  1999cited by this paper
• Interleukin 1 induces multinucleation and bone-resorbing activity of osteoclasts in the absence of osteoblasts/stromal cells.

  1999cited by this paper
• Bone Metabolism in Thalassemia a

  1998cited by this paper
• Bone mineral density in prepubertal children with beta-thalassemia: correlation with growth and hormonal data.

  1998cited by this paper
• A common human beta globin splicing mutation modeled in mice.

  1998cited by this paper
• The Morbidity of Bone Disease in Thalassemia

  1998cited by this paper
• A distinct pattern of cytokine production from blood mononuclear cells in multitransfused patients with β‐thalassaemia

  1997cited by this paper
• Five Jumps per Day Increase Bone Mass and Breaking Force in Rats

  1997cited by this paper
• Evidence for coordinated regulation of osteoblast function by 1,25-dihydroxyvitamin D3 and parathyroid hormone.

  1996cited by this paper
• Exercise effects on bone mass in postmenopausal women are site‐specific and load‐dependent

  1996cited by this paper
• Bone marrow, cytokines, and bone remodeling. Emerging insights into the pathophysiology of osteoporosis.

  1995cited by this paper
• Bone marrow, cytokines, and bone remodeling

  1995cited by this paper
• Increase in femoral bone density in young women following high-impact exercise

  1994cited by this paper
• Regulation of Duodenal Insulin-Like Growth Factor I and Active Calcium Transport by Ovariectomy in Female Rats 1

  1992cited by this paper
• Thalassemia in SouthEast Asia: problems and strategy for prevention and control.

  1992cited by this paper
• Neurosecretory Dysfunction of Growth Hormone Secretion in Thalassemia Major

  1990cited by this paper
• In vivo hematopoietic effects of recombinant interleukin-1 alpha in mice: stimulation of granulocytic, monocytic, megakaryocytic, and early erythroid progenitors, suppression of late-stage erythropoiesis, and reversal of erythroid suppression with erythropoietin.

  1989cited by this paper
• Effect of physical activity on calcium and phosphorus metabolism in the rat.

  1989cited by this paper
• Serum Insulin-Like Growth Factors I and II Concentrations and Growth Hormone and Insulin Responses to Arginine Infusion in Children with Protein-Energy Malnutrition before and after Nutritional Rehabilitation

  1986cited by this paper
• Defective Vitamin D Metabolism in Thalassemia Major

  1985cited by this paper
• Role of intestinal calcium absorption in plasma calcium regulation of the rat.

  1984cited by this paper
• Combined vitamin D parathyroid defect in thalassemia major.

  1982cited by this paper
• Calcium phosphate metabolism and bone disease in patients with homozygous thalassemia.

  1982cited by this paper
• PATHOPHYSIOLOGY OF THALASSEMIA

  1980cited by this paper
• Iron absorption and loading in beta-thalassaemia intermedia.

  1979cited by this paper
• IRON ABSORPTION AND LOADING IN β-THALASSÆMIA INTERMEDIA

  1979cited by this paper
• Serum 25-hydroxyvitamin D levels in thalassaemia.

  1978cited by this paper
• Calcium Metabolism in Children Suffering from Homozygous ß-Thalassaemia after Oral Administration of 47Ca

  1976cited by this paper
• CITRYL-COA. AN SUBSTRATE FOR THE CITRATE-CLEAVAGE ENZYME.

  1963cited by this paper

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  2022cites this paper
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  2020cites this paper
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  2019cites this paper
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  2018cites this paper
• Intestinal calcium transport and its regulation in thalassemia: interaction between calcium and iron metabolism

  2018cites this paper
• Chemokine-like receptor 1 deficiency leads to lower bone mass in male mice

  2018cites this paper
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  2017cites this paper
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  2017cites this paper
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  2016cites this paper
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  2016cites this paper
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  2016cites this paper
• The mechanisms underlying the beneficial effects of exercise on bone remodeling: Roles of bone-derived cytokines and microRNAs.

  2016influential citation
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  2016cites this paper
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