Intestinal calcium transport and its regulation in thalassemia: interaction between calcium and iron metabolism

No abstract is available for this paper.

• Publication year

  2018

• Venue

  Journal of Physiological Sciences

• Publication date

  2018-02-26

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1007/s12576-018-0600-1PMID 29484538PMCID PMC10717198
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Prolonged exposure to 1,25(OH)2D3 and high ionized calcium induces FGF-23 production in intestinal epithelium-like Caco-2 monolayer: A local negative feedback for preventing excessive calcium transport.

  2018cited by this paper
• Non-invasive MRI biomarkers for the early assessment of iron overload in a humanized mouse model of β-thalassemia

  2017cited by this paper
• Combination Iron Chelation Therapy with Deferiprone and Deferasirox in Iron-Overloaded Patients with Transfusion-Dependent β-Thalassemia Major

  2017cited by this paper
• Parathyroid hormone in pediatric patients with β-thalassemia major and its relation to bone mineral density; a case control study

  2017cited by this paper
• Cardiac iron overload in chronically transfused patients with thalassemia, sickle cell anemia, or myelodysplastic syndrome

  2017cited by this paper
• Na+/H+ exchanger 3 inhibitor diminishes hepcidin-enhanced duodenal calcium transport in hemizygous β-globin knockout thalassemic mice

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• Hepcidin and 1,25(OH)2D3 effectively restore Ca2+ transport in β-thalassemic mice: reciprocal phenomenon of Fe2+ and Ca2+ absorption.

  2016cited by this paper
• On the move, lysosomal CAX drives Ca2+ transport and motility

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• Hematological and biochemical status of Beta-thalassemia major patients in Bangladesh: A comparative analysis

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  2016cited by this paper
• Effects of dietary iron intake and chronic kidney disease on fibroblast growth factor 23 metabolism in wild-type and hepcidin knockout mice.

  2016cited by this paper
• Review and Recommendations on Management of Adult Female Thalassemia Patients with Hypogonadism based on Literature Review and Experience of ICET-A Network Specialists

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• Bone Disease in Thalassemia: A Molecular and Clinical Overview.

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  2015cited by this paper
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  2015cited by this paper
• Plasma fibroblast growth factor 23 concentration and iron status. Does the relationship exist in the elderly population?

  2015cited by this paper
• Bone microstructural defects and osteopenia in hemizygous βIVSII-654 knockin thalassemic mice: sex-dependent changes in bone density and osteoclast function.

  2015cited by this paper
• Molecular Aspects of Bone Resorption in β-Thalassemia Major

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  2014cited by this paper
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  2013cited by this paper
• Early-Life Iron Deficiency Anemia Alters the Development and Long-Term Expression of Parvalbumin and Perineuronal Nets in the Rat Hippocampus

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• Copper Deficiency Leads to Anemia, Duodenal Hypoxia, Upregulation of HIF-2α and Altered Expression of Iron Absorption Genes in Mice

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  2013cited by this paper
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  2013cited by this paper
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  2013cited by this paper
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• Thalassemia.

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• Deferasirox reduces iron overload significantly in nontransfusion-dependent thalassemia: 1-year results from a prospective, randomized, double-blind, placebo-controlled study.

  2012cited by this paper
• Fibroblast growth factor-23 abolishes 1,25-dihydroxyvitamin D₃-enhanced duodenal calcium transport in male mice.

  2012cited by this paper
• Pharmacokinetics of Deferiprone in Patients with β-Thalassaemia

  2011cited by this paper
• Evaluation of Growth, Puberty and Endocrine Dysfunctions in Relation to Iron Overload in Multi Transfused Indian Thalassemia Patients

  2011cited by this paper
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  2011cited by this paper
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  2011cited by this paper
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  2011cited by this paper
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  2011cited by this paper
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  2011cited by this paper
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  2011cited by this paper
• Impaired bone formation and osteopenia in heterozygous βIVSII-654 knockin thalassemic mice

  2011cited by this paper
• Pharmacokinetics of Deferiprone in Patients with β-Thalassaemia : Impact of Splenectomy and Iron Status.

  2011cited by this paper
• Phosphate and FGF-23.

  2011cited by this paper
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• Evaluation of Osteopathy in Thalassemia by Bone Mineral Densitometry and Biochemical Indices

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  2009cited by this paper
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  2009cited by this paper
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• Serum Dickkopf-1 is increased and correlates with reduced bone mineral density in patients with thalassemia-induced osteoporosis. Reduction post-zoledronic acid administration

  2008cited by this paper
• Bone Disease in Thalassemia: A Frequent and Still Unresolved Problem

  2008cited by this paper
• Tight junction proteins claudin-2 and -12 are critical for vitamin D-dependent Ca2+ absorption between enterocytes.

  2008cited by this paper
• Calcium homeostasis in 40 adolescents with beta-thalassemia major: a case-control study of the effects of intramuscular injection of a megadose of cholecalciferol.

  2008cited by this paper
• Prolactin is an important regulator of intestinal calcium transport.

  2007cited by this paper
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  2007cited by this paper
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  2007cited by this paper
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  2007cited by this paper
• Prevalence of fractures among the Thalassemia syndromes in North America.

  2006cited by this paper
• Ineffective erythropoiesis in beta-thalassemia is characterized by increased iron absorption mediated by down-regulation of hepcidin and up-regulation of ferroportin.

  2006cited by this paper
• mRNA expression of iron regulatory genes in β‐thalassemia intermedia and β‐thalassemia major mouse models

  2006cited by this paper
• Chelation Therapy and Bone Metabolism Markers in Thalassemia Major

  2006cited by this paper
• mRNA expression of iron regulatory genes in beta-thalassemia intermedia and beta-thalassemia major mouse models.

  2006cited by this paper
• Vesicular transport and apotransferrin in intestinal iron absorption, as shown in the Caco-2 cell model.

  2006cited by this paper
• Low serum levels of 25-hydroxy vitamin D in adults affected by thalassemia major or intermedia.

  2006cited by this paper
• Effects of extracellular iron concentration on calcium absorption and relationship between Ca2+ and cell apoptosis in Caco-2 cells.

  2005cited by this paper
• 1alpha,25-Dihydroxyvitamin D3 upregulates FGF23 gene expression in bone: the final link in a renal-gastrointestinal-skeletal axis that controls phosphate transport.

  2005cited by this paper
• Desferrioxamine mesylate for managing transfusional iron overload in people with transfusion-dependent thalassaemia.

  2005cited by this paper
• Vitamin D receptor-independent FGF23 actions in regulating phosphate and vitamin D metabolism.

  2005cited by this paper
• Regulation of gene expression of epithelial calcium channels in intestine and kidney of mice by 1alpha,25-dihydroxyvitamin D3.

  2004cited by this paper
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  2004cited by this paper
• Prolactin directly stimulated the solvent drag-induced calcium transport in the duodenum of female rats.

  2004cited by this paper
• Bone mineral density, biochemical and hormonal profiles in suboptimally treated children and adolescents with beta-thalassaemia disease.

  2003cited by this paper
• Intestinal Calcium Transporter Genes Are Upregulated by Estrogens and the Reproductive Cycle Through Vitamin D Receptor‐Independent Mechanisms

  2003cited by this paper
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• Hypocalcemia as biological mechanism responsible for prenatal exposure to polycyclic aromatic hydrocarbons (PAHs) and anemia: Insights from Zunyi birth cohort.

  2025cites this paper
• Safety and efficacy of peripheral blood stem cells collection in healthy children and pediatric patients with thalassemia major weighing 20 kg or less

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• Unraveling the Intricate Interplay: Iron and Zinc’s Regulatory Mechanisms on Calcium Bioavailability During Intestinal Absorption

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• CORRELATION BETWEEN CALCIUM SENSING RECEPTOR WITH CALCIUM HOMEOSTASIS IN MAJOR β-THALASSEMIA PATIENTS

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• Caffeic acid and ferulic acid can improve toxicological damage caused by iron overload mediated by carbonic anhydrase inhibition

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  2021cites this paper
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• Iron and Folic Acid Supplementation Affects Mineral Status in Female Rats with a Deficiency of These Micronutrients

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• Intestinal Ca2+ absorption revisited: A molecular and clinical approach

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• The Relationship between Ferritin and Calcium Levels in Patients with Thalassemia β Major

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• Excessive Reactive Iron Impairs Hematopoiesis by Affecting Both Immature Hematopoietic Cells and Stromal Cells

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