Absorption, metabolism, and functions of hyaluronic acid and its therapeutic prospects in combination with microorganisms: A review.

Hyaluronic acid (HA) is key to the stability of the internal environment of tissues. HA content in tissues gradually decreases with age, causing age-related health problems. Exogenous HA supplements are used to prevent or treat these problems including skin dryness and wrinkles, intestinal imbalance, xerophthalmia, and arthritis after absorption. Moreover, some probiotics are able to promote endogenous HA synthesis and alleviate symptoms caused by HA loss, thus introducing potential preventative or therapeutic applications of HA and probiotics. Here, we review the oral absorption, metabolism, and biological function of HA as well as the potential role of probiotics and HA in increasing the efficacy of HA supplements.

• Publication year

  2022

• Venue

  Carbohydrate Polymers

• Publication date

  2022-09-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.carbpol.2022.120153PMID 36876779
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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