Tissue-Resident NK Cells Mediate Ischemic Kidney Injury and Are Not Depleted by Anti–Asialo-GM1 Antibody

No abstract is available for this paper.

• Publication year

  2015

• Venue

  Journal of Immunology

• Publication date

  2015-11-15

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.4049/jimmunol.1500651PMID 26453755PMCID PMC4640895
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• NK cells regulating T cell responses: mechanisms and outcome.

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• Inhibition of the TRAIL Death Receptor by CMV Reveals Its Importance in NK Cell-Mediated Antiviral Defense

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• Cutting Edge: Salivary Gland NK Cells Develop Independently of Nfil3 in Steady-State

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• Uterine NK cells: active regulators at the maternal-fetal interface.

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• Differential Requirement for Nfil3 during NK Cell Development

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• Natural killer (NK) cells augment atherosclerosis by cytotoxic-dependent mechanisms.

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• Ly49 Receptors: Innate and Adaptive Immune Paradigms

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• Conventional NK Cells Can Produce IL-22 and Promote Host Defense in Klebsiella pneumoniae Pneumonia

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• Ischemic neurons recruit natural killer cells that accelerate brain infarction

  2014cited by this paper
• Tissue-resident natural killer (NK) cells are cell lineages distinct from thymic and conventional splenic NK cells

  2014influential reference
• Anti-Asialo GM1 NK Cell Depleting Antibody Does Not Alter the Development of Bleomycin Induced Pulmonary Fibrosis

  2014cited by this paper
• Cytomegalovirus generates long-lived antigen-specific NK cells with diminished bystander activation to heterologous infection

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• TLR2 Signaling in Tubular Epithelial Cells Regulates NK Cell Recruitment in Kidney Ischemia–Reperfusion Injury

  2013influential reference
• Variable NK cell receptors and their MHC class I ligands in immunity, reproduction and human evolution

  2013cited by this paper
• Up-regulation of a death receptor renders antiviral T cells susceptible to NK cell–mediated deletion

  2013cited by this paper
• Liver-resident NK cells confer adaptive immunity in skin-contact inflammation.

  2013influential reference
• Tuning the threshold of natural killer cell responses.

  2013cited by this paper
• Contribution of Thy1+ NK cells to protective IFN-γ production during Salmonella Typhimurium infections

  2013cited by this paper
• Transcription factors involved in the regulation of natural killer cell development and function: an update

  2012cited by this paper
• NK Cells Are Not Required for Spontaneous Autoimmune Diabetes in NOD Mice

  2012cited by this paper
• The transcription factors T-bet and Eomes control key checkpoints of natural killer cell maturation.

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• Intrahepatic Infiltrating NK and CD8 T Cells Cause Liver Cell Death in Different Phases of Dengue Virus Infection

  2012cited by this paper
• NK cell MHC class I specific receptors (KIR): from biology to clinical intervention.

  2012cited by this paper
• IL-22 from conventional NK cells is epithelial regenerative and inflammation protective during influenza infection

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• Lower TCR repertoire diversity in Traj18-deficient mice

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• Severe necroinflammatory reaction caused by natural killer cell‐mediated Fas/Fas ligand interaction and dendritic cells in human hepatocyte chimeric mouse

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• Natural Killer Cells Protect against Mucosal and Systemic Infection with the Enteric Pathogen Citrobacter rodentium

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• CCR2 Defines a Distinct Population of NK Cells and Mediates Their Migration during Influenza Virus Infection in Mice

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• NK Cell-Depleting Anti-Asialo GM1 Antibody Exhibits a Lethal Off-Target Effect on Basophils In Vivo

  2011cited by this paper
• Homeostatic proliferation generates long-lived natural killer cells that respond against viral infection

  2011cited by this paper
• Cellular pathophysiology of ischemic acute kidney injury.

  2011cited by this paper
• Use of a Hanging-weight System for Isolated Renal Artery Occlusion

  2011influential reference
• Reverse signaling through the costimulatory ligand CD137L in epithelial cells is essential for natural killer cell-mediated acute tissue inflammation

  2011influential reference
• Cutting Edge: CD8+ T Cell Priming in the Absence of NK Cells Leads to Enhanced Memory Responses

  2011cited by this paper
• Innate or Adaptive Immunity? The Example of Natural Killer Cells

  2011cited by this paper
• Natural killer (NK)–dendritic cell interactions generate MHC class II-dressed NK cells that regulate CD4+ T cells

  2011cited by this paper
• Toll-like receptor 4 engagement contributes to expression of NKG2D ligands by renal tubular epithelial cells.

  2011cited by this paper
• Memory‐like responses of natural killer cells

  2010cited by this paper
• Membrane nanotubes facilitate long-distance interactions between natural killer cells and target cells

  2010cited by this paper
• Salivary Gland NK Cells Are Phenotypically and Functionally Unique

  2010cited by this paper
• Osteopontin Expressed in Tubular Epithelial Cells Regulates NK Cell-Mediated Kidney Ischemia Reperfusion Injury

  2010cited by this paper
• Effect of NKG2D ligand expression on host immune responses

  2010cited by this paper
• HIF-1alpha accumulation upregulates MICA and MICB expression on human cardiomyocytes and enhances NK cell cytotoxicity during hypoxia-reoxygenation.

  2010cited by this paper
• Hidden talents of natural killers: NK cells in innate and adaptive immunity

  2009cited by this paper
• Cutting Edge: IL-15-Independent NK Cell Response to Mouse Cytomegalovirus Infection1

  2009cited by this paper
• The basic leucine zipper transcription factor E4BP4 is essential for natural killer cell development

  2009cited by this paper
• Natural killer cell cytotoxicity: how do they pull the trigger?

  2009cited by this paper
• IL-4-induced transcription factor NFIL3/E4BP4 controls IgE class switching

  2009cited by this paper
• Nfil3/E4bp4 is required for the development and maturation of NK cells in vivo

  2009cited by this paper
• Natural killer cells are required for accelerated type 1 diabetes driven by interferon‐β

  2008cited by this paper
• Functions of natural killer cells

  2008cited by this paper
• NK Cells Induce Apoptosis in Tubular Epithelial Cells and Contribute to Renal Ischemia-Reperfusion Injury1

  2008influential reference
• NK but Not CD1-Restricted NKT Cells Facilitate Systemic Inflammation during Polymicrobial Intra-Abdominal Sepsis1

  2008cited by this paper
• Inhibitory receptors signal activation.

  2008cited by this paper
• NKT Cell Activation Mediates Neutrophil IFN-γ Production and Renal Ischemia-Reperfusion Injury1

  2007cited by this paper
• NKT cell activation mediates neutrophil IFN-gamma production and renal ischemia-reperfusion injury.

  2007cited by this paper
• Identification, activation, and selective in vivo ablation of mouse NK cells via NKp46

  2007cited by this paper
• Molecular and Genetic Basis for Strain-Dependent NK1.1 Alloreactivity of Mouse NK Cells

  2006cited by this paper
• CD27 Dissects Mature NK Cells into Two Subsets with Distinct Responsiveness and Migratory Capacity1

  2006cited by this paper
• Synergy among receptors on resting NK cells for the activation of natural cytotoxicity and cytokine secretion.

  2006cited by this paper
• Molecular and Genetic Basis for Strain-Dependent NK1.1 Alloreactivity of Mouse NK Cells1

  2006cited by this paper
• NKR-P1 biology

  2006cited by this paper
• Self-tolerance of natural killer cells

  2006cited by this paper
• Roles for Common Cytokine Receptor γ-Chain-Dependent Cytokines in the Generation, Differentiation, and Maturation of NK Cell Precursors and Peripheral NK Cells in Vivo1

  2005cited by this paper
• Coordination of activating and inhibitory signals in natural killer cells.

  2005cited by this paper
• T-bet regulates the terminal maturation and homeostasis of NK and Valpha14i NKT cells.

  2004cited by this paper
• Natural Killer Cell Signaling Pathways

  2004cited by this paper
• Innate immune response to encephalomyocarditis virus infection mediated by CD1d

  2003cited by this paper
• Hypoxia and reoxygenation do not upregulate adhesion molecules and natural killer cell adhesion on human endothelial cells in vitro.

  2003cited by this paper
• Cutting Edge: The Mouse NK Cell-Associated Antigen Recognized by DX5 Moncoclonal Antibody is CD49b (α2 Integrin, Very Late Antigen-2)1

  2001influential reference
• Involvement of tumor necrosis factor-related apoptosis-inducing ligand in surveillance of tumor metastasis by liver natural killer cells

  2001cited by this paper
• Reversible Defects in Natural Killer and Memory Cd8 T Cell Lineages in Interleukin 15–Deficient Mice

  2000cited by this paper
• A simple, nonradioactive method for evaluating single-nephron filtration rate using FITC-inulin.

  1999cited by this paper
• Cd1-Reactive Natural Killer T Cells Are Required for Development of Systemic Tolerance through an Immune-Privileged Site

  1999cited by this paper
• Impaired NK1+ T cell development and early IL-4 production in CD1-deficient mice.

  1997influential reference
• Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor gamma chain.

  1995cited by this paper
• In vivo effect of anti-asialo GM1 antibody on natural killer activity

  1981cited by this paper
• Identification of ganglio-N-tetraosylceramide as a new cell surface marker for murine natural killer (NK) cells.

  1980cited by this paper
• A glycolipid on the surface of mouse natural killer cells

  1980cited by this paper

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• Natural killer cells in kidney immune surveillance, injury and fibrosis

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• Kidney-resident macrophages limit toxin-induced inflammation through their hallmark functions.

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• Metabolic regulation of tissue-resident immune cells: Molecular mechanisms and therapeutic implications.

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• Innate Immune Mechanisms in Normal and Adverse Pregnancy.

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• Identification and Validation of Tryptophan Metabolism–Related Genes in Diabetic Kidney Disease and Construction of a Clinical Prediction Model

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• Innate immune cells in acute and chronic kidney disease

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• Leveraging Integrated RNA Sequencing to Decipher Adrenomedullin’s Protective Mechanisms in Experimental Bronchopulmonary Dysplasia

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• MiR‐21 suppression in macrophages promotes M2‐like polarization and attenuates kidney ischemia–reperfusion injury

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• Glutamine modulates neutrophil recruitment and effector functions during sterile inflammation.

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• Natural killer cell-based cancer immunotherapy: from basics to clinical trials

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• CD94+ natural killer cells potentiate pulmonary ischaemia–reperfusion injury

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• Lymphocytes and innate immune cells in acute kidney injury and repair

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• High Dose of Estrogen Protects the Lungs from Ischemia–Reperfusion Injury by Downregulating the Angiotensin II Signaling Pathway

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• Natural Killer Cells, as the Rising Point in Tissues, Are Forgotten in the Kidney

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• Establishment of anti-asialo-GM1 rabbit monoclonal antibodies capable of reducing natural killer cell activity in mice

  2023cites this paper
• Natural killer cells in the lung: potential role in asthma and virus-induced exacerbation?

  2023cites this paper
• Protective and pathogenic functions of innate lymphoid cells in transplantation.

  2023cites this paper
• Myc controls NK cell development, IL-15-driven expansion, and translational machinery

  2023cites this paper
• The resurgence of the Adora2b receptor as an immunotherapeutic target in pancreatic cancer

  2023cites this paper
• Role of natural killer and B cell interaction in inducing pathogen specific immune responses

  2023cites this paper
• Early immune and host cell responses to Cryptosporidium infection

  2023cites this paper
• Tissue-Dependent Adaptations and Functions of Innate Lymphoid Cells

  2022cites this paper
• Natural killer cell-mediated immunopathology in recurrent pregnancy losses Exploration of Immunology

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• Natural killer cell-mediated immunopathology in recurrent pregnancy losses

  2022cites this paper
• Metabolic signatures of immune cells in chronic kidney disease

  2022cites this paper
• LFA-1/ ICAM-1 promotes NK cell cytotoxicity associated with the pathogenesis of ocular toxoplasmosis in murine model

  2022cites this paper
• Inflammation Controls Susceptibility of Immune-Experienced Mice to Sepsis

  2022cites this paper
• Alternative adenosine Receptor activation: The netrin-Adora2b link

  2022cites this paper
• The functional diversity of tissue‐resident natural killer cells against infection

  2022cites this paper
• Updated Views on Neutrophil Responses in Ischemia–Reperfusion Injury

  2022cites this paper
• NK Cells and ILC1s in Cancer Biology.

  2022cites this paper
• Tissue Immunity in the Bladder.

  2022cites this paper
• SARS-CoV-2 Infection: Host Response, Immunity, and Therapeutic Targets

  2022cites this paper
• Natural killer cells in inflammatory autoimmune diseases

  2021cites this paper
• The innate immune system in human kidney inflammaging

  2021cites this paper
• Signatures and Specificity of Tissue-Resident Lymphocytes Identified in Human Renal Peritumor and Tumor Tissue

  2021cites this paper
• Group 1 innate lymphoid-cell-derived interferon-γ maintains anti-viral vigilance in the mucosal epithelium.

  2021cites this paper
• Natural killer cells in reproduction: Before, during and after pregnancy

  2021cites this paper
• Innate (and Innate-like) Lymphoid Cells: Emerging Immune Subsets With Multiple Roles Along Transplant Life

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• NK Cells in Autoimmune Diseases: Protective or Pathogenic?

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• Natural Killer Cell Integrins and Their Functions in Tissue Residency

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• NK Cell–Derived IL-10 Supports Host Survival during Sepsis

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• Acute Kidney Injury and Regenerative Medicine

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• A shift toward inhibitory receptors and impaired effector functions on NK cells contribute to immunosuppression during sepsis

  2020cites this paper
• Progression or suppression: Two sides of the innate lymphoid cells in cancer

  2020cites this paper
• Tissue Determinants of Human NK Cell Development, Function, and Residence.

  2020influential citation
• Uterine Natural Killer Cell Heterogeneity: Lessons From Mouse Models

  2020cites this paper
• Tissue-resident NK cells and other innate lymphoid cells.

  2020cites this paper
• Transcriptional Regulation of Mouse Tissue-Resident Natural Killer Cell Development

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• Prevention of liver metastases through perioperative acute CpG-C immune stimulation

  2020cites this paper
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• Engineering antibody-based molecules for HIV treatment and cure.

  2020cites this paper
• Recent Advances in the Role of Natural Killer Cells in Acute Kidney Injury

  2020cites this paper
• Kidney Protection: Strategies for Renal Preservation.

  2020cites this paper
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  2020cites this paper
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  2020cites this paper
• Type 1 innate lymphoid cells: Soldiers at the front line of immunity

  2020influential citation
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• Tissue-resident lymphocytes: from adaptive to innate immunity

  2019cites this paper
• Anti-CD8 monoclonal antibody-mediated depletion alters the phenotype and behavior of surviving CD8+ T cells

  2019cites this paper
• Natural Killer Cells in Kidney Health and Disease

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• The biology of natural killer cells during sepsis

  2018cites this paper
• Uterine natural killer cells: To protect and to nurture

  2018cites this paper
• Cutting Edge: Local Proliferation of Uterine Tissue-Resident NK Cells during Decidualization in Mice

  2018cites this paper
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  2018cites this paper
• Role of Hepatic Deposited Immunoglobulin G in the Pathogenesis of Liver Damage in Systemic Lupus Erythematosus

  2018cites this paper
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  2018cites this paper
• Tissue-Resident Cytolytic Innate Lymphocytes in Cancer

  2018cites this paper
• Natural killer cells in liver diseases

  2018cites this paper
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  2018cites this paper
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  2018cites this paper
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  2017cites this paper
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  2017cites this paper
• Parabiosis Reveals Leukocyte Dynamics in the Kidney

  2017cites this paper
• Liver-resident NK cells and their potential functions

  2017cites this paper
• NK cell subsets in autoimmune diseases.

  2017cites this paper
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  2017cites this paper
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  2017cites this paper
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  2017cites this paper
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  2017cites this paper
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