Stem cells and regeneration in planarians.

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Frontiers in Bioscience

• Publication date

  2008-05-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.2741/3160PMID 18508666
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Planarians, a tale of stem cells.

  2008cited by this paper
• Silencing of Smed-βcatenin1 generates radial-like hypercephalized planarians

  2008cited by this paper
• β-Catenin Defines Head Versus Tail Identity During Planarian Regeneration and Homeostasis

  2008cited by this paper
• Smed-βcatenin-1 Is Required for Anteroposterior Blastema Polarity in Planarian Regeneration

  2008cited by this paper
• Cell type complexity in the basal metazoan Hydra is maintained by both stem cell based mechanisms and transdifferentiation.

  2008cited by this paper
• The BMP pathway is essential for re-specification and maintenance of the dorsoventral axis in regenerating and intact planarians.

  2007cited by this paper
• Advances in signaling in vertebrate regeneration as a prelude to regenerative medicine.

  2007cited by this paper
• Regeneration and maintenance of the planarian midline is regulated by a slit orthologue.

  2007cited by this paper
• Bone morphogenetic protein is required for dorso‐ventral patterning in the planarian Dugesia japonica

  2007cited by this paper
• Gtdap-1 promotes autophagy and is required for planarian remodeling during regeneration and starvation

  2007cited by this paper
• DjCBC‐1, a conserved DEAD box RNA helicase of the RCK/p54/Me31B family, is a component of RNA‐protein complexes in planarian stem cells and neurons

  2007cited by this paper
• Deciphering the molecular machinery of stem cells: a look at the neoblast gene expression profile

  2007cited by this paper
• nanos function is essential for development and regeneration of planarian germ cells

  2007cited by this paper
• smedinx-11 is a planarian stem cell gap junction gene required for regeneration and homeostasis

  2007cited by this paper
• SmedGD: the Schmidtea mediterranea genome database

  2007cited by this paper
• Embryonic stem cell transplantation: potential applicability in cell replacement therapy and regenerative medicine.

  2007cited by this paper
• The adult Drosophila malpighian tubules are maintained by multipotent stem cells.

  2007cited by this paper
• Characterization and categorization of fluorescence activated cell sorted planarian stem cells by ultrastructural analysis

  2007cited by this paper
• The planarian nanos-like gene Smednos is expressed in germline and eye precursor cells during development and regeneration

  2007cited by this paper
• Reprogramming somatic gene activity by fusion with pluripotent cells

  2007cited by this paper
• The exceptional stem cell system of Macrostomum lignano: Screening for gene expression and studying cell proliferation by hydroxyurea treatment and irradiation

  2007cited by this paper
• Regenerating the central nervous system: how easy for planarians!

  2007cited by this paper
• BMP signaling regulates the dorsal planarian midline and is needed for asymmetric regeneration

  2007cited by this paper
• Identification and origin of the germline stem cells as revealed by the expression of nanos‐related gene in planarians

  2006cited by this paper
• A Bruno-like gene is required for stem cell maintenance in planarians.

  2006cited by this paper
• RNA granules

  2006cited by this paper
• Free-living flatworms under the knife: past and present

  2006cited by this paper
• The stem cell concept in sponges (Porifera): Metazoan traits.

  2006cited by this paper
• The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells

  2006cited by this paper
• Isolation of planarian X‐ray‐sensitive stem cells by fluorescence‐activated cell sorting

  2006cited by this paper
• Molecular control of pluripotency.

  2006cited by this paper
• Early segregation of germ and somatic lineages during gonadal regeneration in the annelid Enchytraeus japonensis.

  2006cited by this paper
• Early embryogenesis of planaria: a cryptic larva feeding on maternal resources

  2006cited by this paper
• DjPiwi-1, a member of the PAZ-Piwi gene family, defines a subpopulation of planarian stem cells

  2006cited by this paper
• The power of regeneration and the stem-cell kingdom: freshwater planarians (Platyhelminthes).

  2006cited by this paper
• Hydra, a niche for cell and developmental plasticity.

  2006cited by this paper
• Core transcriptional regulatory circuitry in human embryonic stem cells.

  2005cited by this paper
• Planarian homologs of netrin and netrin receptor are required for proper regeneration of the central nervous system and the maintenance of nervous system architecture

  2005cited by this paper
• The planarian Schmidtea mediterranea as a model for epigenetic germ cell specification: analysis of ESTs from the hermaphroditic strain.

  2005cited by this paper
• The embryonic development of the triclad Schmidtea polychroa

  2005cited by this paper
• Developmental cell biology: Regulatory networks in embryo-derived pluripotent stem cells

  2005cited by this paper
• Distribution of the stem cells (neoblasts) in the planarian Dugesia japonica

  2005cited by this paper
• Interaction between Oct3/4 and Cdx2 determines trophectoderm differentiation.

  2005cited by this paper
• DjPum, a homologue of Drosophila Pumilio, is essential to planarian stem cell maintenance

  2005cited by this paper
• Stem cell niche: structure and function.

  2005cited by this paper
• SMEDWI-2 Is a PIWI-Like Protein That Regulates Planarian Stem Cells

  2005cited by this paper
• Multigene analyses of bilaterian animals corroborate the monophyly of Ecdysozoa, Lophotrochozoa, and Protostomia.

  2005cited by this paper
• Identification of genes needed for regeneration, stem cell function, and tissue homeostasis by systematic gene perturbation in planaria.

  2005cited by this paper
• Proximodistal patterning during limb regeneration.

  2005cited by this paper
• Embryonic stem cell differentiation: emergence of a new era in biology and medicine.

  2005cited by this paper
• Gli3 and Plzf cooperate in proximal limb patterning at early stages of limb development

  2005cited by this paper
• Differential tissue development during embryogenesis and regeneration in an annelid

  2004cited by this paper
• Mesenchymal-epithelial interactions in the bladder

  2004cited by this paper
• Stem cells for Parkinson disease and ALS: replacement or protection?

  2004cited by this paper
• Stem cell dynamics during growth, feeding, and starvation in the basal flatworm Macrostomum sp. (Platyhelminthes)

  2004cited by this paper
• Transgenic planarian lines obtained by electroporation using transposon-derived vectors and an eye-specific GFP marker

  2003cited by this paper
• Gtwnt-5 a member of the wnt family expressed in a subpopulation of the nervous system of the planarian Girardia tigrina.

  2003cited by this paper
• Allometric scaling and proportion regulation in the freshwater planarian Schmidtea mediterranea

  2003cited by this paper
• The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells.

  2003cited by this paper
• Origin and evolutionary process of the CNS elucidated by comparative genomics analysis of planarian ESTs

  2003cited by this paper
• Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells.

  2003cited by this paper
• Epithelial mesenchymal interactions, the ECM and limb development

  2003cited by this paper
• A simple "soaking method" for RNA interference in the planarian Dugesia japonica

  2003cited by this paper
• Ingestion of bacterially expressed double-stranded RNA inhibits gene expression in planarians

  2003cited by this paper
• BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3.

  2003cited by this paper
• Switching from Asexual to Sexual Reproduction in the Planarian Dugesia ryukyuensis: Change of the Fissiparous Capacity along with the Sexualizing Process

  2002cited by this paper
• Mesenchymal-epithelial interactions in lung development and repair: are modeling and remodeling the same process?

  2002cited by this paper
• Dissecting planarian central nervous system regeneration by the expression of neural‐specific genes

  2002cited by this paper
• Regeneration in planarians and other worms: New findings, new tools, and new perspectives.

  2002cited by this paper
• A re-examination of proximodistal patterning during vertebrate limb development

  2002cited by this paper
• Planarian fibroblast growth factor receptor homologs expressed in stem cells and cephalic ganglions

  2002cited by this paper
• Dorsal and ventral positional cues required for the onset of planarian regeneration may reside in differentiated cells.

  2001cited by this paper
• Searching for the prototypic eye genetic network: Sine oculis is essential for eye regeneration in planarians.

  2000cited by this paper
• Bromodeoxyuridine specifically labels the regenerative stem cells of planarians.

  2000cited by this paper
• The new animal phylogeny: reliability and implications.

  2000cited by this paper
• An MCM2‐related gene is expressed in proliferating cells of intact and regenerating planarians

  2000cited by this paper
• Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells

  2000cited by this paper
• Intercalary muscle cell renewal in planarian pharynx

  1999cited by this paper
• The role of dorsoventral interaction in the onset of planarian regeneration.

  1999cited by this paper
• Molecular and cellular aspects of planarian regeneration.

  1999cited by this paper
• Expression of vasa(vas)-related genes in germline cells and totipotent somatic stem cells of planarians.

  1999cited by this paper
• Double-stranded RNA specifically disrupts gene expression during planarian regeneration.

  1999cited by this paper
• Embryonic stem cell lines derived from human blastocysts.

  1998cited by this paper
• Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3.

  1998cited by this paper
• Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4.

  1998cited by this paper
• A planarian orthopedia homolog is specifically expressed in the branch region of both the mature and regenerating brain

  1997cited by this paper
• Amphibian Limb Regeneration: Rebuilding a Complex Structure

  1997cited by this paper
• The cellular basis of limb regeneration in urodeles.

  1996cited by this paper
• Homeobox genes and pattern formation in the vertebrate limb.

  1992cited by this paper
• Observations on planarian epithelization after wounding.

  1989cited by this paper
• Inhibition of pluripotential embryonic stem cell differentiation by purified polypeptides

  1988cited by this paper
• Cell movement in intact and regenerating planarians. Quantitation using chromosomal, nuclear and cytoplasmic markers.

  1985cited by this paper
• Regeneration and pattern formation in planarians. I. The pattern of mitosis in anterior and posterior regeneration in Dugesia (G) tigrina, and a new proposal for blastema formation.

  1984cited by this paper
• Formation of germ-line chimaeras from embryo-derived teratocarcinoma cell lines

  1984cited by this paper
• Evidence of male germ cell redifferentiation into female germ cells in planarian regeneration.

  1982cited by this paper
• Cell death and acid phosphatase activity in the regenerating planarian Polycelis tenuis Iijima.

  1982cited by this paper
• Establishment in culture of pluripotential cells from mouse embryos

  1981cited by this paper
• Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells.

  1981cited by this paper
• On the role of germ cells in planarian regeneration. I. A karyological investigation.

  1980cited by this paper
• The regeneration of positional information in the amphibian limb.

  1977cited by this paper

• Recent clinical trials with stem cells to slow or reverse normal aging processes

  2023cites this paper
• Djhsp70s, especially Djhsp70c, play a key role in planarian regeneration and tissue homeostasis by regulating cell proliferation and apoptosis.

  2022cites this paper
• Djptpn11 is indispensable for planarian regeneration by affecting early wound response genes expression and the Wnt pathway.

  2022cites this paper
• TBX2/3 is required for regeneration of dorsal‐ventral and medial‐lateral polarity in planarians

  2021cites this paper
• Cytology, function and dynamics of stem and progenitor cells in decapod crustaceans

  2021cites this paper
• The Diverse Manifestations of Regeneration and Why We Need to Study Them.

  2021cites this paper
• A pan‐metazoan concept for adult stem cells: the wobbling Penrose landscape

  2021cites this paper
• Stem cells of aquatic invertebrates as an advanced tool for assessing ecotoxicological impacts.

  2021cites this paper
• Scarless wound healingとアカハライモリ

  2020cites this paper
• Planarian Regeneration: Connecting Lab Exercises & Scientific Modeling

  2020cites this paper
• Identification of rare transient somatic cell states induced by injury and required for whole-body regeneration

  2020cites this paper
• Djmek is involved in planarian regeneration by regulation of cell proliferation and apoptosis.

  2020cites this paper
• Exportin-1 is required for the maintenance of the planarian epidermal lineage.

  2019cites this paper
• Bibliography

  2019cites this paper
• Drug delivery and epimorphic salamander‐type mouse regeneration: A full parts and labor plan

  2018cites this paper
• Immunohistochemistry on Paraffin-Embedded Planarian Tissue Sections.

  2018cites this paper
• Pattern Regeneration in Coupled Networks

  2018cites this paper
• Identification of runt family genes involved in planarian regeneration and tissue homeostasis.

  2018cites this paper
• Gap junctional signaling in pattern regulation: Physiological network connectivity instructs growth and form

  2017cites this paper
• Identification and characterization of a novel multifunctional placenta specific protein 8 in Dugesia japonica.

  2017cites this paper
• Biochemical and Molecular Study of Carpobrotus edulis Bioactive Properties and Their Effects on Dugesia sicula (Turbellaria, Tricladida) Regeneration

  2017cites this paper
• Comparative Proteomic Analysis of the Effect of the Four-Herb Chinese Medicine ANBP on Promoting Mouse Skin Wound Healing

  2017cites this paper
• Epigenetic regulation via methylation on histone H3K27 is involved in leg regeneration patterning and photoperiodic responses of the circadian clock in the cricket Gryllus bimaculatus

  2016cites this paper
• Evolution of the EGFR pathway in Metazoa and its diversification in the planarian Schmidtea mediterranea

  2016cites this paper
• A transcriptional time-course analysis of oral vs. aboral whole-body regeneration in the Sea anemone Nematostella vectensis

  2016cites this paper
• Early exposure of rotating magnetic fields promotes central nervous regeneration in planarian Girardia sinensis

  2016cites this paper
• De Novo Transcriptome Analysis Provides Insights into Immune Related Genes and the RIG-I-Like Receptor Signaling Pathway in the Freshwater Planarian (Dugesia japonica)

  2016cites this paper
• Induced Pluripotent Stem Cells: Next Generation Cells for Tissue Regeneration

  2016cites this paper
• Growth and Scaling during Development and Regeneration

  2016cites this paper
• Caracterización funcional de la vía Wnt/Bcatenina en el restablecimiento y mantenimiento del eje anteroposterior durante la regeneración y homeostasis de la planaria Schmidtea mediterranea

  2016cites this paper
• Planarian myosin essential light chain is involved in the formation of brain lateral branches during regeneration

  2015cites this paper
• Regenerated leg segment patterns are regulated epigenetically by histone H3K27 methylation in the cricket Gryllus bimaculatus

  2015cites this paper
• Leg regeneration is epigenetically regulated by histone H3K27 methylation in the cricket Gryllus bimaculatus

  2015cites this paper
• Cloning and characterization of DjPRPS gene in freshwater planarian Dugesia japonica

  2015cites this paper
• Cloning and characterization of DjPRPS gene in freshwater planarian Dugesia japonica / [DjPRPS geninin tatlısu planaryası Dugesia japonica’da tanımlanması ve klonlanması]

  2015cites this paper
• DEV122598 2916..2927

  2015cites this paper
• The stability of memories during brain remodeling: A perspective

  2015cites this paper
• iTRAQ-based proteomic analysis of adaptive response in the regenerating limb of the Cynops orientalis newt.

  2015cites this paper
• iTRAQ-Based Quantitative Proteomic Analysis of the Initiation of Head Regeneration in Planarians

  2015cites this paper
• Designing Self-Assembling Structures of Particles and Cells

  2015cites this paper
• JNK Controls the Onset of Mitosis in Planarian Stem Cells and Triggers Apoptotic Cell Death Required for Regeneration and Remodeling

  2014cites this paper
• Planarians Sense Simulated Microgravity and Hypergravity

  2014cites this paper
• Making Heads or Tails: Planarian Stem Cells in the Classroom

  2014cites this paper
• A linear-encoding model explains the variability of the target morphology in regeneration

  2014cites this paper
• Effects of N,N-dimethylformamide on behaviour and regeneration of planarian Dugesia japonica

  2013cites this paper
• The Hippo Pathway Regulates Stem Cells During Homeostasis and Regeneration of the Flatworm Macrostomum Lignano

  2013cites this paper
• Advancing the flatworm Macrostomum lignano as a versatile model organism for stem cell research

  2013influential citation
• Posterior regeneration in Isodiametra pulchra (Acoela, Acoelomorpha)

  2013cites this paper
• Mortalin and Stem Cells: A Study from Planarians

  2012cites this paper
• Hidden Treasures in Stem Cells of Indeterminately Growing Bilaterian Invertebrates

  2012cites this paper
• Space Research Program on Planarian Schmidtea Mediterranea’s Establishment of the Anterior-Posterior Axis in Altered Gravity Conditions

  2012cites this paper
• Stem Cells Propagate Their DNA by Random Segregation in the Flatworm Macrostomum lignano

  2012cites this paper
• Effects of dimethylsulfoxide on behavior and antioxidant enzymes response of planarian Dugesia japonica

  2012cites this paper
• Stem cell protection mechanisms in planarians: the role of some heat shock genes.

  2012cites this paper
• Heterogeneity of planarian stem cells in the S/G2/M phase.

  2012cites this paper
• Small RNA pathways in Schmidtea mediterranea.

  2012cites this paper
• Modeling Planarian Regeneration: A Primer for Reverse-Engineering the Worm

  2012cites this paper
• Inhibitory Smads and bone morphogenetic protein (BMP) modulate anterior photoreceptor cell number during planarian eye regeneration.

  2012cites this paper
• Deorphanization of biogenic amine-responsive G protein-coupled receptors in various model protozoa and platyhelminthes

  2012cites this paper
• Space Research Program on Planarian Schmidtea Mediterranea’s Establishment of the Anterior-Posterior Axis in Altered Gravity Conditions

  2012cites this paper
• Reference genes for qPCR assays in toxic metal and salinity stress in two flatworm model organisms

  2012cites this paper
• La regeneració i l'homeòstasi en les planàries, un model clàssic de biologia del desenvolupament

  2011cites this paper
• Planarian stem cells: a simple paradigm for regeneration.

  2011cites this paper
• The Regenerative Capacity of the Zebrafish Caudal Fin Is Not Affected by Repeated Amputations

  2011cites this paper
• De novo assembly and validation of planaria transcriptome by massive parallel sequencing and shotgun proteomics.

  2011cites this paper
• Expression patterns of the STAG gene in intact and regenerating planarians (Dugesia japonica).

  2011cites this paper
• The head-regeneration transcriptome of the planarian Schmidtea mediterranea

  2011cites this paper
• A proteomics approach to decipher the molecular nature of planarian stem cells

  2011cites this paper
• Loss of DNA Mismatch Repair Imparts a Selective Advantage in Planarian Adult Stem Cells

  2011cites this paper
• Expression pattern and function of eIFE4 isoforms in planarian adult stem cells

  2011influential citation
• Characterization and expression of DjPreb gene in the planarian Dugesia japonica

  2010cites this paper
• Echinoderm immunity

  2010cites this paper
• Molecular and cellular mechanisms of heart regeneration in zebrafish

  2010cites this paper
• Imaginal discs: Renaissance of a model for regenerative biology

  2010cites this paper
• Neurogenesis in mouse models of Alzheimer's disease.

  2010cites this paper
• Gradients in planarian regeneration and homeostasis.

  2010cites this paper
• Cell plasticity in homeostasis and regeneration

  2010cites this paper
• Cell death-induced regeneration in wing imaginal discs requires JNK signalling

  2010cites this paper
• Autophagy and apoptosis in planarians

  2010cites this paper
• The planarian flatworm: an in vivo model for stem cell biology and nervous system regeneration

  2010cites this paper
• Potential of Macrostomum lignano to recover from γ-ray irradiation

  2010cites this paper
• Characterization of the stem cell system of the acoel Isodiametra pulchra

  2009cites this paper
• SpolvlgA is a DDX3/PL10-related DEAD-box RNA helicase expressed in blastomeres and embryonic cells in planarian embryonic development

  2009cites this paper
• Autophagy meets planarians

  2009cites this paper
• Fatty acid content and composition of freshwater planaria Dendrocoelopsis sp. (Planariidae, Turbellaria, Platyhelminthes) from the Yenisei River

  2009cites this paper
• Expression pattern of the expanded noggin gene family in the planarian Schmidtea mediterranea.

  2009cites this paper
• A mortalin-like gene is crucial for planarian stem cell viability.

  2009cites this paper
• Spoltud-1 is a chromatoid body component required for planarian long-term stem cell self-renewal.

  2009cites this paper
• Planarian regeneration: achievements and future directions after 20 years of research.

  2009cites this paper
• Comparative biology of aging.

  2009cites this paper
• New method to deliver exogenous material into developing planarian embryos.

  2008cites this paper