Dopamine/serotonin releasers as medications for stimulant addictions.

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Progress in Brain Research

• Publication date

  Unknown publication date

• Fields of study

  Medicine, Psychology

• Identifiers
  DOI 10.1016/S0079-6123(08)00919-9PMID 18772043
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• Drugs and valvular heart disease.

  2007influential reference
• Monoamine Releasers with Varying Selectivity for Dopamine/Norepinephrine versus Serotonin Release as Candidate “Agonist” Medications for Cocaine Dependence: Studies in Assays of Cocaine Discrimination and Cocaine Self-Administration in Rhesus Monkeys

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  2003influential reference
• Monoamine transporters and psychostimulant drugs.

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