p53, proto-oncogene and rheumatoid arthritis.

No abstract is available for this paper.

• Publication year

  2002

• Venue

  Seminars in Arthritis & Rheumatism

• Publication date

  2002-04-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1053/SARH.2002.31550PMID 11965594
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• What destroys the joint in rheumatoid arthritis?

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• Phenotypic characterization of 3H-thymidine incorporating cells in rheumatoid arthritis synovial membrane

  2004cited by this paper
• Invasiveness of synovial fibroblasts is regulated by p53 in the SCID mouse in vivo model of cartilage invasion.

  2001cited by this paper
• Suppression of arthritis by forced expression of cyclin-dependent kinase inhibitor p21(Cip1) gene into the joints.

  2001cited by this paper
• Gene transfer of p53 to arthritic joints stimulates synovial apoptosis and inhibits inflammation.

  2001cited by this paper
• Apoptosis in rheumatoid arthritis – expression of Fas, Fas‐L, p53, and Bcl‐2 in rheumatoid synovial tissues

  2001cited by this paper
• Synovial membrane p53 protein immunoreactivity in rheumatoid arthritis patients

  2000cited by this paper
• The p53 status in juvenile chronic arthritis and rheumatoid arthritis

  2000cited by this paper
• p300/CBP-dependent and -independent transcriptional interference between NF-kappaB RelA and p53.

  2000cited by this paper
• Apoptosis of articular chondrocytes in rheumatoid arthritis and osteoarthritis: correlation of apoptosis with degree of cartilage destruction and expression of apoptosis-related proteins of p53 and c-myc

  2000cited by this paper
• Rheumatoid Arthritis Synovial Stromal Cells Inhibit Apoptosis and Up-Regulate Bcl-xL Expression by B Cells in a CD49/CD29-CD106-Dependent Mechanism1

  2000cited by this paper
• Bcl-2 Expression in Synovial Fibroblasts Is Essential for Maintaining Mitochondrial Homeostasis and Cell Viability1

  2000cited by this paper
• Adenoviral expression of p53 represses telomerase activity through down-regulation of human telomerase reverse transcriptase transcription.

  2000cited by this paper
• Adenoviral Transfer of Cyclin-Dependent Kinase Inhibitor Genes Suppresses Collagen-Induced Arthritis in Mice1

  2000cited by this paper
• Wild Type and Mutant p53 Differentially Regulate the Gene Expression of Human Collagenase-3 (hMMP-13)*

  2000cited by this paper
• Rheumatoid arthritis and p53: how oxidative stress might alter the course of inflammatory diseases.

  2000cited by this paper
• Analysis of p53 tumour suppressor gene somatic mutations in rheumatoid arthritis synovium.

  2000cited by this paper
• Selective toxicity of MKT-077 to cancer cells is mediated by its binding to the hsp70 family protein mot-2 and reactivation of p53 function.

  2000cited by this paper
• Wild-type p53 suppresses angiogenesis in human leiomyosarcoma and synovial sarcoma by transcriptional suppression of vascular endothelial growth factor expression.

  2000cited by this paper
• Inhibition of Cyclooxygenase-2 Gene Expression by p53*

  1999cited by this paper
• Analysis of the p53 tumor suppressor gene in rheumatoid arthritis synovial fibroblasts.

  1999cited by this paper
• Dominant-negative p53 mutations in rheumatoid arthritis.

  1999cited by this paper
• Inhibition of p53 Transcriptional Activity by Bcl-2 Requires Its Membrane-anchoring Domain*

  1999cited by this paper
• p53 Negatively Regulates cdc2 Transcription via the CCAAT-binding NF-Y Transcription Factor*

  1999cited by this paper
• p53 overexpression in synovial tissue from patients with early and longstanding rheumatoid arthritis compared with patients with reactive arthritis and osteoarthritis.

  1999cited by this paper
• C-myc antisense oligodeoxynucleotides can induce apoptosis and down-regulate Fas expression in rheumatoid synoviocytes.

  1999cited by this paper
• p53 Down-regulates Human Matrix Metalloproteinase-1 (Collagenase-1) Gene Expression*

  1999cited by this paper
• p53-dependent effects of RAS oncogene on chromosome stability and cell cycle checkpoints

  1999cited by this paper
• Mutations of the p53 tumour suppressor gene in erosive rheumatoid synovial tissue

  1998cited by this paper
• Antisense oligonucleotides targeting c-fos mRNA inhibit rheumatoid synovial fibroblast proliferation

  1998cited by this paper
• The p53 Network*

  1998cited by this paper
• Regulation of synoviocyte proliferation, apoptosis, and invasion by the p53 tumor suppressor gene.

  1998cited by this paper
• The Bcl-2 protein family: arbiters of cell survival.

  1998cited by this paper
• Induction of apoptosis in the rheumatoid synovium by Fas ligand gene transfer

  1998cited by this paper
• p53-mediated repression of nuclear factor-kappaB RelA via the transcriptional integrator p300.

  1998cited by this paper
• Bcl-2 family proteins

  1998cited by this paper
• Inactivation of Tumor Suppressor p53 by Mot-2, a hsp70 Family Member*

  1998cited by this paper
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  1998cited by this paper
• [Rheumatoid arthritis synoviocyte hyperplasia and expression of fas and bcl-2 genes].

  1998cited by this paper
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  1998cited by this paper
• Detection of p53 in inflammatory tissue and lymphocytes using immunohistology and flow cytometry: a critical comment.

  1997cited by this paper
• Inhibition of T cell apoptosis in the rheumatoid synovium.

  1997cited by this paper
• Amelioration of collagen-induced arthritis by CD95 (Apo-1/Fas)-ligand gene transfer.

  1997cited by this paper
• Mdm2 promotes the rapid degradation of p53

  1997cited by this paper
• Recruitment of p300/CBP in p53-dependent signal pathways.

  1997cited by this paper
• p53, the Cellular Gatekeeper Review for Growth and Division

  1997cited by this paper
• The role of T cells in the immunopathogenesis of rheumatoid arthritis: new perspectives.

  1997cited by this paper
• H-ras oncogene point mutations in arthritic synovium.

  1997cited by this paper
• Regulation of human interstitial collagenase (matrix metalloproteinase-1) promoter activity by fibroblast growth factor.

  1997cited by this paper
• Repression of glucocorticoid receptor transactivation and DNA binding of a glucocorticoid response element within the serum/glucocorticoid-inducible protein kinase (sgk) gene promoter by the p53 tumor suppressor protein.

  1997cited by this paper
• Bcl-2 inhibits p53 nuclear import following DNA damage

  1997cited by this paper
• Somatic mutations in the p53 tumor suppressor gene in rheumatoid arthritis synovium.

  1997cited by this paper
• Interleukin-1beta-stimulated invasion of articular cartilage by rheumatoid synovial fibroblasts is inhibited by antibodies to specific integrin receptors and by collagenase inhibitors.

  1997cited by this paper
• Matrix metalloproteinase 13 (collagenase 3) in human rheumatoid synovium.

  1997cited by this paper
• Direct evidence of high DNA binding activity of transcription factor AP-1 in rheumatoid arthritis synovium.

  1997cited by this paper
• Inhibition of rheumatoid synovial fibroblast proliferation by antisense oligonucleotides targeting proliferating cell nuclear antigen messenger RNA.

  1997cited by this paper
• Inhibition of rheumatoid synovial fibroblast proliferation by antisense oligonucleotides targeting proliferating cell nuclear antigen messenger rna

  1997cited by this paper
• Invasive fibroblast-like synoviocytes in rheumatoid arthritis. Passive responders or transformed aggressors?

  1996cited by this paper
• Synovial fibroblasts of patients with rheumatoid arthritis attach to and invade normal human cartilage when engrafted into SCID mice.

  1996cited by this paper
• Localisation of apoptosis and expression of apoptosis related proteins in the synovium of patients with rheumatoid arthritis.

  1996cited by this paper
• Biochemical Characterization of Human Collagenase-3 (*)

  1996cited by this paper
• p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells.

  1996cited by this paper
• Importance of the Bcl-2 family in cell death regulation

  1996cited by this paper
• Degradation of cartilage aggrecan by collagenase‐3 (MMP‐13)

  1996cited by this paper
• Constitutive expression of c-fos and c-jun, overexpression of ets-2, and reduced expression of metastasis suppressor gene nm23-H1 in rheumatoid arthritis.

  1996cited by this paper
• Stimulation of 92-kDa Gelatinase B Promoter Activity by ras Is Mitogen-activated Protein Kinase Kinase 1-independent and Requires Multiple Transcription Factor Binding Sites Including Closely Spaced PEA3/ets and AP-1 Sequences (*)

  1996cited by this paper
• Regulating expression of the gene for matrix metalloproteinase-1 (collagenase): mechanisms that control enzyme activity, transcription, and mRNA stability.

  1996cited by this paper
• Apoptosis in rheumatoid arthritis: p53 overexpression in rheumatoid arthritis synovium.

  1996cited by this paper
• Apoptosis in rheumatoid arthritis synovium.

  1995cited by this paper
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  1995cited by this paper
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• Comparative analysis of cathepsin L, cathepsin D, and collagenase messenger RNA expression in synovial tissues of patients with rheumatoid arthritis and osteoarthritis, by in situ hybridization.

  1995cited by this paper
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  1994cited by this paper
• Transcriptional regulation of basic fibroblast growth factor gene by p53 in human glioblastoma and hepatocellular carcinoma cells.

  1994cited by this paper
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  1994cited by this paper
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