Routine invasive strategy within 24 hours of thrombolysis versus ischaemia-guided conservative approach for acute myocardial infarction with ST-segment elevation (GRACIA-1): a randomised controlled trial.

No abstract is available for this paper.

• Publication year

  2004

• Venue

  The Lancet

• Publication date

  2004-09-18

• Fields of study

  Medicine

• Identifiers
  DOI 10.1016/S0140-6736(04)17059-1PMID 15380963
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2003cited by this paper
• "Watchful waiting" after thrombolysis: it's time for a re-evaluation.

  2003cited by this paper
• Early and long-term clinical outcomes associated with reinfarction following fibrinolytic administration in the Thrombolysis in Myocardial Infarction trials.

  2003cited by this paper
• Management of acute myocardial infarction in patients presenting with ST-segment elevation. The Task Force on the Management of Acute Myocardial Infarction of the European Society of Cardiology.

  2003cited by this paper
• Early and sustained dual oral antiplatelet therapy following percutaneous coronary intervention: a randomized controlled trial.

  2002cited by this paper
• Comparison of angioplasty with stenting in acute myocardial infarction.

  2002cited by this paper
• A prospective survey of the characteristics, treatments and outcomes of patients with acute coronary syndromes in Europe and the Mediterranean basin; the Euro Heart Survey of Acute Coronary Syndromes (Euro Heart Survey ACS).

  2002cited by this paper
• Early revascularisation and 1-year survival in 14-day survivors of acute myocardial infarction: a prospective cohort study.

  2002cited by this paper
• Safety of coronary stenting early after thrombolysis in patients with acute myocardial infarction: One‐ and six‐month clinical and angiographic evolution

  2002cited by this paper
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  2002cited by this paper
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  2002cited by this paper
• Platelet glycoprotein IIb/IIIa inhibition with coronary stenting for acute myocardial infarction.

  2001cited by this paper
• Application of the TIMI risk score for ST-elevation MI in the National Registry of Myocardial Infarction 3.

  2001cited by this paper
• ACC/AHA Guidelines for Percutaneous Coronary Intervention (Revision of the 1993 PTCA Guidelines)—Executive Summary

  2001cited by this paper
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  2000cited by this paper
• [The clinical management guidelines of the Sociedad Española de Cardiología in acute myocardial infarct].

  1999cited by this paper
• A randomized trial comparing primary angioplasty with a strategy of short-acting thrombolysis and immediate planned rescue angioplasty in acute myocardial infarction: the PACT trial. PACT investigators. Plasminogen-activator Angioplasty Compatibility Trial.

  1999cited by this paper
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  1999cited by this paper
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  1999cited by this paper
• Coronary angioscopic findings in the infarct-related vessel within 1 month of acute myocardial infarction: natural history and the effect of thrombolysis.

  1998cited by this paper
• Safety and Cost-Effectiveness of Early Discharge After Primary Angioplasty in Low Risk Patients With Acute Myocardial Infarction

  1998cited by this paper
• Safety and cost-effectiveness of early discharge after primary angioplasty in low risk patients with acute myocardial infarction. PAMI-II Investigators. Primary Angioplasty in Myocardial Infarction.

  1998cited by this paper
• Clinical and angiographic implications of coronary stenting in thrombus-containing lesions.

  1997cited by this paper
• Reocclusion: the flip side of coronary thrombolysis.

  1996cited by this paper
• Does PTCA in acute myocardial infarction affect mortality and reinfarction rates? A quantitative overview (meta-analysis) of the randomized clinical trials.

  1995cited by this paper
• Adverse long-term effects of reocclusion after coronary thrombolysis.

  1995cited by this paper
• Indications for fibrinolytic therapy in suspected acute myocardial infarction: collaborative overview of early mortality and major morbidity results from all randomised trials of more than 1000 patients. Fibrinolytic Therapy Trialists' (FTT) Collaborative Group.

  1994cited by this paper
• Indications for fibrinolytic therapy in suspected acute myocardial infarction : collaborative overview of early mortality and major morbidity results from all randomised trials of more than 1000 patients

  1994cited by this paper
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  1993cited by this paper
• Guidelines for percutaneous transluminal coronary angioplasty. A report of the American College of Cardiology/American Heart Association Task Force on Assessment of Diagnostic and Therapeutic Cardiovascular Procedures (Committee on Percutaneous Transluminal Coronary Angioplasty).

  1993cited by this paper
• Culprit lesion morphology and stenosis severity in the prediction of reocclusion after coronary thrombolysis: angiographic results of the APRICOT study. Antithrombotics in the Prevention of Reocclusion in Coronary Thrombolysis.

  1993cited by this paper
• SWIFT trial of delayed elective intervention v conservative treatment after thrombolysis with anistreplase in acute myocardial infarction. SWIFT (Should We Intervene Following Thrombolysis?) Trial Study Group.

  1991cited by this paper
• Comparison of invasive and conservative strategies after treatment with intravenous tissue plasminogen activator in acute myocardial infarction. Results of the thrombolysis in myocardial infarction (TIMI) phase II trial.

  1989cited by this paper
• Thrombolysis with tissue plasminogen activator in acute myocardial infarction: no additional benefit from immediate percutaneous coronary angioplasty.

  1988cited by this paper
• Factors influencing reocclusion after coronary thrombolysis for acute myocardial infarction.

  1986cited by this paper
• The Thrombolysis in Myocardial Infarction (TIMI) trial. Phase I findings.

  1985cited by this paper
• The thrombolysis in myocardial infarction (TIMI) trial.

  1985cited by this paper
• Letter: Ultrasound and safety.

  1976cited by this paper

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  2025cites this paper
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  2025cites this paper
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  2024cites this paper
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  2024cites this paper
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  2023cites this paper
• 2023 ESC Guidelines for the management of acute coronary syndromes.

  2023cites this paper
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  2023cites this paper
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  2022cites this paper
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  2021cites this paper
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  2021cites this paper
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  2021cites this paper
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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
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  2019cites this paper
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  2019cites this paper
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  2019cites this paper
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  2018cites this paper
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  2018cites this paper
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  2018cites this paper
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  2018cites this paper
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  2018cites this paper
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  2018cites this paper
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  2018cites this paper
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  2018cites this paper
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  2018cites this paper
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  2018cites this paper
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  2018cites this paper
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  2018cites this paper
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  2017cites this paper
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  2017cites this paper
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  2017cites this paper
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  2017cites this paper
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  2017cites this paper
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  2017cites this paper
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  2017cites this paper
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  2017cites this paper
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  2016cites this paper
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  2016cites this paper
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  2016cites this paper
• Modelo de intervención coronaria percutánea primaria en la Comunidad

  2016cites this paper
• Very Early versus Early Invasive Strategy after Successful Thrombolysis in Patients with ST Segment Elevation Myocardial Infarction

  2016influential citation
• Pre‐hospital thrombolysis in ST‐segment elevation myocardial infarction: a regional Australian experience

  2016cites this paper
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  2016cites this paper
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  2016cites this paper
• uropean Resuscitation Council Guidelines for Resuscitation 2015 ection 8 . Initial management of acute coronary syndromes

  2015cites this paper
• Long-term mortality following interhospital transfer for acute myocardial infarction

  2015cites this paper
• Guía de práctica clínica de la ESC sobre revascularización miocárdica, 2014

  2015cites this paper
• Why Acute Coronary Syndromes?

  2015cites this paper
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  2015cites this paper
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  2015cites this paper
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  2015cites this paper
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  2015cites this paper
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  2015cites this paper
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  2015influential citation
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  2015cites this paper
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  2015cites this paper
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  2015cites this paper
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  2015cites this paper
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  2015cites this paper
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  2015cites this paper
• Part 5: Acute Coronary Syndromes: 2015 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations.

  2015cites this paper
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  2015cites this paper
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  2015cites this paper
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  2015cites this paper
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  2015cites this paper
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  2015cites this paper
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  2014cites this paper
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  2014cites this paper
• Management of STEMI in low- and middle-income countries.

  2014cites this paper
• [2014 ESC/EACTS Guidelines on myocardial revascularization].

  2014cites this paper
• Weaknesses in regional primary coronary angioplasty programs: is there still a role for a pharmaco-invasive approach?

  2014cites this paper
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  2014cites this paper