Nutritional Cues Control Pseudomonas aeruginosa Multicellular Behavior in Cystic Fibrosis Sputum

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Journal of Bacteriology

• Publication date

  2007-09-14

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1128/JB.01138-07PMID 17873029PMCID PMC2168676
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2005cited by this paper
• Microcolony formation: a novel biofilm model of Pseudomonas aeruginosa for the cystic fibrosis lung.

  2005cited by this paper
• Composition of sputum from patients with cystic fibrosis

  2005cited by this paper
• Pseudomonas aeruginosa regulates flagellin expression as part of a global response to airway fluid from cystic fibrosis patients.

  2004cited by this paper
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  2004cited by this paper
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  2004cited by this paper
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  2004cited by this paper
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  2004cited by this paper
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  2003cited by this paper
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  2003cited by this paper
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  2003cited by this paper
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  2002cited by this paper
• Effects of reduced mucus oxygen concentration in airway Pseudomonas infections of cystic fibrosis patients.

  2002cited by this paper
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  2002cited by this paper
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  2002cited by this paper
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  2002cited by this paper
• Lipopolysaccharide endotoxins.

  2002cited by this paper
• Lung Infections Associated with Cystic Fibrosis

  2002cited by this paper
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  2001cited by this paper
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  2001cited by this paper
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  2001cited by this paper
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  2001cited by this paper
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  2001cited by this paper
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  2000cited by this paper
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  2000cited by this paper
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  2000cited by this paper
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  1999cited by this paper
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  1999cited by this paper
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  1999cited by this paper
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  1999cited by this paper
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  1999cited by this paper
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  1998cited by this paper
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  1997cited by this paper
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  1997cited by this paper
• Isolation and characterization of Pseudomonas aeruginosa genes inducible by respiratory mucus derived from cystic fibrosis patients

  1996cited by this paper
• Common virulence factors for bacterial pathogenicity in plants and animals.

  1995cited by this paper
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  1992cited by this paper
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  1992cited by this paper
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  1991cited by this paper
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  1991cited by this paper
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  1990cited by this paper
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  1990cited by this paper
• [Iron deficiency and Pseudomonas aeruginosa colonization in cystic fibrosis].

  1989cited by this paper
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  1989cited by this paper
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  1985cited by this paper
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