Transcriptional regulation of T cell tolerance.

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Seminars in Immunology

• Publication date

  2007-06-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/J.SMIM.2007.02.006PMID 17387022PMCID PMC1978193
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• Involvement of NFAT1 in B Cell Self-Tolerance1

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• Foxp3+CD25+CD4+ natural regulatory T cells in dominant self‐tolerance and autoimmune disease

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• Disruption of diacylglycerol metabolism impairs the induction of T cell anergy

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• NFAT transcription factors in control of peripheral T cell tolerance

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• Distinct Molecular Program Imposed on CD4+ T Cell Targets by CD4+CD25+ Regulatory T Cells1

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• Two isoforms of otubain 1 regulate T cell anergy via GRAIL

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• A Conserved Docking Motif for CK1 Binding Controls the Nuclear Localization of NFAT1

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• Smad3 Is Essential for TGF-β1 to Suppress IL-2 Production and TCR-Induced Proliferation, but Not IL-2-Induced Proliferation1

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• Murine CD4+CD25+ Regulatory T Cells Fail to Undergo Chromatin Remodeling Across the Proximal Promoter Region of the IL-2 Gene1

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• Structure of NFAT1 bound as a dimer to the HIV-1 LTR κB element

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• Transcriptional regulation by calcium, calcineurin, and NFAT.

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• T cell anergy.

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• Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

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• An asymmetric NFAT1 dimer on a pseudo-palindromic κB-like DNA site

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• GRAIL: an E3 ubiquitin ligase that inhibits cytokine gene transcription is expressed in anergic CD4+ T cells.

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• GRAIL : An E 3 Ubiquitin Ligase that Inhibits Cytokine Gene Transcription Is Expressed in Anergic CD 4 T Cells tumors

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• Ca2+/calcineurin signalling in cells of the immune system.

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• Foxp 3 programs the development and function of CD 4 + CD 25 + regulatory T cells

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• Structure of NFAT bound to DNA as a monomer.

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• Interferon Regulatory Factor 4 (IRF4) Interacts with NFATc2 to Modulate Interleukin 4 Gene Expression

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• Supporting Online Material

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• TH cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes

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• NFAT signaling: choreographing the social lives of cells.

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• Transcriptional mechanisms underlying lymphocyte tolerance.

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• Haematopoietic cell-fate decisions, chromatin regulation and ikaros

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• The enemy within: keeping self-reactive T cells at bay in the periphery

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• Partners in transcription: NFAT and AP-1

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• Fingerprints of anergic T cells.

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