Effects of obesity‐associated plasma markers on adipose stem cell function and epigenetic regulation

This study investigates the correlations between obesity‐related plasma markers and epigenetic/inflammatory changes in white adipose tissue (WAT), focusing on adipose‐derived stem cells (ASCs). We hypothesize that obesity modulates histone H3K27 marks, modified by demethylases (lysine‐specific demethylase 6A and 6B [KDM6A/KDM6B]) and acetylases (CREB–binding protein [CREBBP]/histone acetyltransferase EP300), affecting ASC function.

• Publication year

  2025

• Venue

  Obesity

• Publication date

  2025-06-16

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1002/oby.24321PMID 40518865PMCID 12304845
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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