Molecular Cloning of Apobec-1 Complementation Factor, a Novel RNA-Binding Protein Involved in the Editing of Apolipoprotein B mRNA

No abstract is available for this paper.

• Publication year

  2000

• Venue

  Molecular and Cellular Biology

• Publication date

  2000-03-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/MCB.20.5.1846-1854.2000PMID 10669759PMCID PMC85365
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Escherichia coli cytidine deaminase provides a molecular model for ApoB RNA editing and a mechanism for RNA substrate recognition.

  1998cited by this paper
• A Sequence-Specific RNA-Binding Protein Complements Apobec-1 To Edit Apolipoprotein B mRNA

  1998cited by this paper
• Inhibition of the Apolipoprotein B mRNA Editing Enzyme-Complex by hnRNP C1 Protein and 40S hnRNP Complexes

  1998influential reference
• A guide to RNA editing.

  1997cited by this paper
• Partial Characterization of the Auxiliary Factors Involved in Apolipoprotein B mRNA Editing through APOBEC-1 Affinity Chromatography*

  1997cited by this paper
• Apobec-1 and apolipoprotein B mRNA editing.

  1997influential reference
• RNA editing and hypermutation by adenosine deamination.

  1997cited by this paper
• Cloning of an Apobec-1-binding Protein That Also Interacts with Apolipoprotein B mRNA and Evidence for Its Involvement in RNA Editing*

  1997cited by this paper
• Apobec-1 Interacts with a 65-kDa Complementing Protein to Edit Apolipoprotein-B mRNA in Vitro *

  1996cited by this paper
• An auxiliary factor containing a 240-kDa protein complex is involved in apolipoprotein B RNA editing.

  1996cited by this paper
• Mass spectrometric sequencing of proteins silver-stained polyacrylamide gels.

  1996cited by this paper
• Base-modification mRNA editing through deamination--the good, the bad and the unregulated.

  1996cited by this paper
• RNA editing.

  1996cited by this paper
• Biosynthesis of Apolipoprotein B48-containing Lipoproteins

  1996cited by this paper
• Cloning of cDNAs encoding mammalian double-stranded RNA-specific adenosine deaminase

  1995cited by this paper
• Evolutionary origins of apoB mRNA editing: catalysis by a cytidine deaminase that has acquired a novel RNA-binding motif at its active site.

  1995cited by this paper
• apobec-1, the Catalytic Subunit of the Mammalian Apolipoprotein B mRNA Editing Enzyme, Is a Novel RNA-binding Protein (*)

  1995influential reference
• Conserved structures and diversity of functions of RNA-binding proteins.

  1994influential reference
• Molecular cloning of a human small intestinal apolipoprotein B mRNA editing protein.

  1994cited by this paper
• Direct interaction of the U1 snRNP-A protein with the upstream efficiency element of the SV40 late polyadenylation signal.

  1994cited by this paper
• Cloning and characterization of human type 2 and type 3 inositol 1,4,5-trisphosphate receptors.

  1994cited by this paper
• Expression and characterization of p27, the catalytic subunit of the apolipoprotein B mRNA editing enzyme.

  1994cited by this paper
• Cloning and mutagenesis of the rabbit ApoB mRNA editing protein. A zinc motif is essential for catalytic activity, and noncatalytic auxiliary factor(s) of the editing complex are widely distributed.

  1994cited by this paper
• Complementation of apolipoprotein B mRNA editing by human liver accompanied by secretion of apolipoprotein B48.

  1994influential reference
• Dimeric structure of a human apolipoprotein B mRNA editing protein and cloning and chromosomal localization of its gene.

  1994cited by this paper
• RNA binding specificity of hnRNP A1: significance of hnRNP A1 high‐affinity binding sites in pre‐mRNA splicing.

  1994influential reference
• Apolipoprotein B mRNA editing in 12 different mammalian species: hepatic expression is reflected in low concentrations of apoB-containing plasma lipoproteins.

  1993influential reference
• Induction of RNA editing at heterologous sites by sequences in apolipoprotein B mRNA

  1993cited by this paper
• Apolipoprotein B mRNA editing is associated with UV crosslinking of proteins to the editing site.

  1993cited by this paper
• The p27 catalytic subunit of the apolipoprotein B mRNA editing enzyme is a cytidine deaminase.

  1993cited by this paper
• Molecular cloning of an apolipoprotein B messenger RNA editing protein.

  1993cited by this paper
• Extract-specific heterogeneity in high-order complexes containing apolipoprotein B mRNA editing activity and RNA-binding proteins.

  1993cited by this paper
• Evolution of intestinal apolipoprotein B mRNA editing. Chicken apolipoprotein B mRNA is not edited, but chicken enterocytes contain in vitro editing enhancement factor(s).

  1992cited by this paper
• Apolipoprotein B, the major protein component of triglyceride-rich and low density lipoproteins.

  1992influential reference
• Characterization of apolipoprotein B mRNA editing from rabbit intestine.

  1992influential reference
• The multiple RNA-binding domains of the mRNA poly(A)-binding protein have different RNA-binding activities

  1991cited by this paper
• Sequence requirements for the editing of apolipoprotein B mRNA.

  1991cited by this paper
• In vitro apolipoprotein B mRNA editing: identification of a 27S editing complex.

  1991cited by this paper
• Apolipoprotein B mRNA editing is an intranuclear event that occurs posttranscriptionally coincident with splicing and polyadenylation.

  1991cited by this paper
• Characterization of the apolipoprotein B mRNA editing enzyme: no similarity to the proposed mechanism of RNA editing in kinetoplastid protozoa

  1991influential reference
• RNA‐Editing

  1990cited by this paper
• A 40 kilodalton rat liver nuclear protein binds specifically to apolipoprotein B mRNA around the RNA editing site.

  1990cited by this paper
• Characterization of the apolipoprotein B mRNA editing activity in enterocyte extracts.

  1990cited by this paper
• An in vitro system for the editing of apolipoprotein B mRNA.

  1989cited by this paper
• A novel form of tissue-specific RNA processing produces apolipoprotein-B48 in intestine.

  1987cited by this paper
• Apolipoprotein B-48 is the product of a messenger RNA with an organ-specific in-frame stop codon.

  1987influential reference

• Two codes of RNA editing by deamination in human diseases.

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• CircMTND5 participates in tubulointerstitial injury in lupus nephritis by binding with A1CF protein.

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• APOBEC-1 Complementation Factor: From RNA Binding to Cancer

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• A1CF Binding to the p65 Interaction Site on NKRF Decreased IFN-β Expression and p65 Phosphorylation (Ser536) in Renal Carcinoma Cells

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• RNA Editing in Cancer Progression

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• Precise and efficient C-to-U RNA base editing with SNAP-CDAR-S

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• Downregulation of RNA binding protein 47 predicts low survival in patients and promotes the development of renal cell malignancies through RNA stability modification

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• Transcriptional Regulation of Human Arylamine N-Acetyltransferase 2 Gene by Glucose and Insulin in Liver Cancer Cell Lines.

  2022cites this paper
• Functions and consequences of AID/APOBEC-mediated DNA and RNA deamination

  2022cites this paper
• C-to-U RNA Editing: A Site Directed RNA Editing Tool for Restoration of Genetic Code

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• C-to-U RNA Editing: From Computational Detection to Experimental Validation.

  2021cites this paper
• RNA binding motif 47 (RBM47): emerging roles in vertebrate development, RNA editing and cancer

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• Potential APOBEC-mediated RNA editing of the genomes of SARS-CoV-2 and other coronaviruses and its impact on their longer term evolution

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• Live-Cell Quantification of APOBEC1-Mediated RNA Editing: A Comparison of RNA Editing Assays.

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• APOBEC1 mediated C-to-U RNA editing: target sequence and trans-acting factor contribution to 177 RNA editing events in 119 murine transcripts in vivo

  2021cites this paper
• Transcriptome-wide organization of subcellular microenvironments revealed by ATLAS-Seq

  2020cites this paper
• Apobec1 complementation factor overexpression promotes hepatic steatosis, fibrosis, and hepatocellular cancer.

  2020influential citation
• The Role of APOBECs in Viral Replication

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• A mark of disease: how mRNA modifications shape genetic and acquired pathologies

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• The structure of APOBEC1 and insights into its RNA and DNA substrate selectivity

  2020cites this paper
• High APOBEC1 Complementation Factor Expression Positively Modulates the Proliferation, Invasion, and Migration of Endometrial Cancer Cells Through Regulating P53/P21 Signaling Pathway

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• Off-target Editing by CRISPR-guided DNA base editors.

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• A 1 CF-Axin 2 signal axis regulates apoptosis and migration in Wilms tumor-derived cells through Wnt / β-catenin pathway

  2019cites this paper
• Mouse APOBEC1 cytidine deaminase can induce somatic mutations in chromosomal DNA

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  2019cites this paper
• The RNA-Binding Protein A1CF Regulates Hepatic Fructose and Glycerol Metabolism via Alternative RNA Splicing.

  2019cites this paper
• Curcumin modulates the apolipoprotein B mRNA editing by coordinating the expression of cytidine deamination to uridine editosome components in primary mouse hepatocytes

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• Modeling the Embrace of a Mutator: APOBEC Selection of Nucleic Acid Ligands

  2018cites this paper
• RNA-binding protein A1CF modulates plasma triglyceride levels through posttranscriptional regulation of stress-induced VLDL secretion

  2018cites this paper
• Dimerisation of APOBEC1 is dispensable for its RNA/DNA editing activity and modulates its availability

  2018cites this paper
• A High-Throughput Approach to Uncover Novel Roles of APOBEC2, A Functional Orphan of the AID/APOBEC Family

  2018cites this paper
• RNA Editors, Cofactors, and mRNA Targets: An Overview of the C-to-U RNA Editing Machinery and Its Implication in Human Disease

  2018cites this paper
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  2018cites this paper
• Dimerisation of APOBEC1 is dispensable for its RNA editing activity

  2018cites this paper
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  2018cites this paper
• When MicroRNAs Meet RNA Editing in Cancer: A Nucleotide Change Can Make a Difference

  2018cites this paper
• The Evolution of Substrate Specificity by tRNA Modification Enzymes.

  2017cites this paper
• Exome-wide association study of plasma lipids in >300,000 individuals

  2017cites this paper
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  2017cites this paper
• Exome-wide association study of plasma lipids in >300,000 individuals

  2017cites this paper
• APOBEC: From mutator to editor.

  2017cites this paper
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  2016cites this paper
• Parent-of-origin effects of A1CF and AGO2 on testicular germ-cell tumors, testicular abnormalities, and fertilization bias

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• Apobec3G-Based Strategies to Defeat HIV Infection.

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• Apobec-1 Complementation Factor (A1CF) Inhibits Epithelial-Mesenchymal Transition and Migration of Normal Rat Kidney Proximal Tubular Epithelial Cells

  2016influential citation
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• Functions and Malfunctions of Mammalian DNA-Cytosine Deaminases.

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• APOBEC3A Is Implicated in a Novel Class of G-to-A mRNA Editing in WT1 Transcripts

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