The multifaceted roles of RNA binding in APOBEC cytidine deaminase functions

No abstract is available for this paper.

• Publication year

  2014

• Venue

  Wiley Interdisciplinary Reviews - RNA

• Publication date

  2014-07-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1002/wrna.1226PMID 24664896PMCID PMC4062598
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• Human LINE-1 restriction by APOBEC3C is deaminase independent and mediated by an ORF1p interaction that affects LINE reverse transcriptase activity

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• Atomic force microscopy studies of APOBEC3G oligomerization and dynamics.

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  2012cited by this paper
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  2012cited by this paper
• The APOBEC3C crystal structure and the interface for HIV-1 Vif binding

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• Random Mutagenesis MAPPIT Analysis Identifies Binding Sites for Vif and Gag in Both Cytidine Deaminase Domains of Apobec3G

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• Creative deaminases, self‐inflicted damage, and genome evolution

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• AID and Apobec3G haphazard deamination and mutational diversity

  2012cited by this paper
• APOBEC2 is a monomer in solution: implications for APOBEC3G models.

  2012cited by this paper
• Intensity of Deoxycytidine Deamination of HIV-1 Proviral DNA by the Retroviral Restriction Factor APOBEC3G Is Mediated by the Noncatalytic Domain*

  2011cited by this paper
• Direct evidence that RNA inhibits APOBEC3G ssDNA cytidine deaminase activity.

  2011cited by this paper
• Functional analysis of the two cytidine deaminase domains in APOBEC3G.

  2011cited by this paper
• Deaminase Activity on Single-stranded DNA (ssDNA) Occurs in Vitro when APOBEC3G Cytidine Deaminase Forms Homotetramers and Higher-order Complexes*

  2011cited by this paper
• Human and Rhesus APOBEC3D, APOBEC3F, APOBEC3G, and APOBEC3H Demonstrate a Conserved Capacity To Restrict Vif-Deficient HIV-1

  2011cited by this paper
• APOBEC3A can activate the DNA damage response and cause cell‐cycle arrest

  2011cited by this paper
• APOBEC3G: a double agent in defense.

  2011cited by this paper
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  2011cited by this paper
• Intrinsic restriction activity by apolipoprotein B mRNA editing enzyme APOBEC1 against the mobility of autonomous retrotransposons

  2011cited by this paper
• Atomic Force Microscopy Studies Provide Direct Evidence for Dimerization of the HIV Restriction Factor APOBEC3G

  2010cited by this paper
• Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency

  2010cited by this paper
• Definition of the interacting interfaces of Apobec3G and HIV-1 Vif using MAPPIT mutagenesis analysis

  2010cited by this paper
• The mechanisms regulating the subcellular localization of AID

  2010cited by this paper
• Structural Model for Deoxycytidine Deamination Mechanisms of the HIV-1 Inactivation Enzyme APOBEC3G*♦

  2010cited by this paper
• APOBEC‐1‐mediated RNA editing

  2010cited by this paper
• Rationalisation of the Differences between APOBEC3G Structures from Crystallography and NMR Studies by Molecular Dynamics Simulations

  2010cited by this paper
• Crystal structure of the APOBEC3G catalytic domain reveals potential oligomerization interfaces.

  2010cited by this paper
• Cytidine deaminases: AIDing DNA demethylation?

  2010cited by this paper
• Transcriptome-wide sequencing reveals numerous APOBEC1 mRNA editing targets in transcript 3′ UTRs

  2010cited by this paper
• Metabolic regulation of APOBEC-1 complementation factor trafficking in mouse models of obesity and its positive correlation with the expression of ApoB protein in hepatocytes.

  2010cited by this paper
• Diverse functions for DNA and RNA editing in the immune system

  2010cited by this paper
• APOBEC1-Mediated Editing and Attenuation of Herpes Simplex Virus 1 DNA Indicate That Neurons Have an Antiviral Role during Herpes Simplex Encephalitis

  2010cited by this paper
• Apobec-1 Complementation Factor Modulates Liver Regeneration by Post-transcriptional Regulation of Interleukin-6 mRNA Stability*

  2010cited by this paper
• A Portable Hot Spot Recognition Loop Transfers Sequence Preferences from APOBEC Family Members to Activation-induced Cytidine Deaminase*

  2009cited by this paper
• An extended structure of the APOBEC3G catalytic domain suggests a unique holoenzyme model.

  2009cited by this paper
• RNA-Dependent Oligomerization of APOBEC3G Is Required for Restriction of HIV-1

  2009cited by this paper
• Intracellular interactions between APOBEC3G, RNA, and HIV-1 Gag: APOBEC3G multimerization is dependent on its association with RNA

  2009cited by this paper
• Human APOBEC1 cytidine deaminase edits HBV DNA

  2009cited by this paper
• Sole copy of Z2‐type human cytidine deaminase APOBEC3H has inhibitory activity against retrotransposons and HIV‐1.

  2009cited by this paper
• Model structure of APOBEC3C reveals a binding pocket modulating ribonucleic acid interaction required for encapsidation

  2009cited by this paper
• A hydrodynamic analysis of APOBEC3G reveals a monomer-dimer-tetramer self-association that has implications for anti-HIV function.

  2009cited by this paper
• Definition of the interacting interfaces of Apobec3G and HIV-1 Vif using MAPPIT mutagenesis analysis

  2009cited by this paper
• Structure, interaction and real‐time monitoring of the enzymatic reaction of wild‐type APOBEC3G

  2009cited by this paper
• Decreased Expression of Cholesterol 7α-Hydroxylase and Altered Bile Acid Metabolism in Apobec-1−/− Mice Lead to Increased Gallstone Susceptibility*

  2009cited by this paper
• Two Regions within the Amino-Terminal Half of APOBEC3G Cooperate To Determine Cytoplasmic Localization

  2008cited by this paper
• APOBEC3G Inhibits Elongation of HIV-1 Reverse Transcripts

  2008cited by this paper
• Distinct viral determinants for the packaging of human cytidine deaminases APOBEC3G and APOBEC3C.

  2008cited by this paper
• Structure of the DNA deaminase domain of the HIV-1 restriction factor APOBEC3G

  2008cited by this paper
• The APOBEC1 Paradigm for Mammalian Cytidine Deaminases That Edit DNA and RNA

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• The AID/APOBEC family of nucleic acid mutators

  2008cited by this paper
• Interaction with 7SL RNA but not with HIV-1 genomic RNA or P bodies is required for APOBEC3F virion packaging.

  2008cited by this paper
• APOBEC3G Subunits Self-associate via the C-terminal Deaminase Domain*

  2008cited by this paper
• Nuclear Exclusion of the HIV-1 Host Defense Factor APOBEC3G Requires a Novel Cytoplasmic Retention Signal and Is Not Dependent on RNA Binding*

  2008cited by this paper
• Guidelines for Naming Nonprimate APOBEC3 Genes and Proteins

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• A Model for Oligomeric Regulation of APOBEC3G Cytosine Deaminase-dependent Restriction of HIV*

  2008cited by this paper
• Crystal structure of the anti-viral APOBEC3G catalytic domain and functional implications

  2008cited by this paper
• RNA and DNA editing : molecular mechanisms and their integration into biological systems

  2008influential reference
• The Interaction of APOBEC3G with Human Immunodeficiency Virus Type 1 Nucleocapsid Inhibits tRNA3Lys Annealing to Viral RNA

  2007cited by this paper
• Derepression of MicroRNA-mediated Protein Translation Inhibition by Apolipoprotein B mRNA-editing Enzyme Catalytic Polypeptide-like 3G (APOBEC3G) and Its Family Members*

  2007cited by this paper
• Functional characterization of APOBEC-1 complementation factor phosphorylation sites.

  2007cited by this paper
• APOBEC3 proteins: major players in intracellular defence against LINE-1-mediated retrotransposition.

  2007cited by this paper
• Deletion of the AU-rich RNA binding protein Apobec-1 reduces intestinal tumor burden in Apc(min) mice.

  2007cited by this paper
• The APOBEC-2 crystal structure and functional implications for the deaminase AID

  2007cited by this paper
• Selective inhibition of Alu retrotransposition by APOBEC3G.

  2007cited by this paper
• Evolution and diversification of lamprey antigen receptors: evidence for involvement of an AID-APOBEC family cytosine deaminase

  2007cited by this paper
• Cytidine Deaminases APOBEC3G and APOBEC3F Interact with Human Immunodeficiency Virus Type 1 Integrase and Inhibit Proviral DNA Formation

  2007cited by this paper
• All APOBEC3 family proteins differentially inhibit LINE-1 retrotransposition

  2007cited by this paper
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  2007cited by this paper
• Newly Synthesized APOBEC3G Is Incorporated into HIV Virions, Inhibited by HIV RNA, and Subsequently Activated by RNase H

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• Human Immunodeficiency Virus Type 1 cDNAs Produced in the Presence of APOBEC3G Exhibit Defects in Plus-Strand DNA Transfer and Integration

  2007cited by this paper
• Supplemental materials and methods

  2006cited by this paper
• APOBEC3A and APOBEC3B are potent inhibitors of LTR-retrotransposon function in human cells

  2006cited by this paper
• Biochemical Activities of Highly Purified, Catalytically Active Human APOBEC3G: Correlation with Antiviral Effect

  2006cited by this paper
• APOBEC3A is a potent inhibitor of adeno-associated virus and retrotransposons.

  2006cited by this paper
• APOBEC3G DNA deaminase acts processively 3′ → 5′ on single-stranded DNA

  2006cited by this paper
• APOBEC3 Proteins Inhibit Human LINE-1 Retrotransposition*

  2006cited by this paper
• Structural Phylogenetic Analysis of Activation-Induced Deaminase Function12

  2006cited by this paper
• High-molecular-mass APOBEC3G complexes restrict Alu retrotransposition

  2006cited by this paper
• Metabolic regulation of ApoB mRNA editing is associated with phosphorylation of APOBEC-1 complementation factor

  2006cited by this paper
• Dual inhibitory effects of APOBEC family proteins on retrotransposition of mammalian endogenous retroviruses

  2006cited by this paper
• Nanostructures of APOBEC3G Support a Hierarchical Assembly Model of High Molecular Mass Ribonucleoprotein Particles from Dimeric Subunits*

  2006cited by this paper
• Mammalian C to U Editing

  2006cited by this paper
• The Anti-HIV-1 Editing Enzyme APOBEC3G Binds HIV-1 RNA and Messenger RNAs That Shuttle between Polysomes and Stress Granules*

  2006cited by this paper
• Distinct Patterns of Cytokine Regulation of APOBEC3G Expression and Activity in Primary Lymphocytes, Macrophages, and Dendritic Cells*

  2006cited by this paper
• APOBEC3B and APOBEC3F Inhibit L1 Retrotransposition by a DNA Deamination-independent Mechanism*

  2006cited by this paper
• Interferon‐inducible expression of APOBEC3 editing enzymes in human hepatocytes and inhibition of hepatitis B virus replication

  2006cited by this paper
• Targeted Deletion of the Murine apobec-1 Complementation Factor (acf) Gene Results in Embryonic Lethality

  2005cited by this paper
• APOBEC4, a New Member of the AID/APOBEC Family of Polynucleotide (Deoxy)Cytidine Deaminases Predicted by Computational Analysis

  2005cited by this paper
• Cellular APOBEC3G restricts HIV-1 infection in resting CD4+ T cells

  2005cited by this paper
• Mutational comparison of the single-domained APOBEC3C and double-domained APOBEC3F/G anti-retroviral cytidine deaminases provides insight into their DNA target site specificities

  2005cited by this paper
• APOBEC3G hypermutates genomic DNA and inhibits Ty1 retrotransposition in yeast.

  2005cited by this paper
• Complementary function of the two catalytic domains of APOBEC3G.

  2005cited by this paper
• Activation-induced Cytidine Deaminase Deaminates 5-Methylcytosine in DNA and Is Expressed in Pluripotent Tissues

  2004cited by this paper
• APOBEC3G Is Incorporated into Virus-like Particles by a Direct Interaction with HIV-1 Gag Nucleocapsid Protein*

  2004cited by this paper
• Activation-induced cytidine deaminase shuttles between nucleus and cytoplasm like apolipoprotein B mRNA editing catalytic polypeptide 1

  2004cited by this paper
• The structure of a yeast RNA-editing deaminase provides insight into the fold and function of activation-induced deaminase and APOBEC-1.

  2004cited by this paper
• APOBEC-Mediated Editing of Viral RNA

  2004cited by this paper
• Human Apolipoprotein B mRNA-editing Enzyme-catalytic Polypeptide-like 3G (APOBEC3G) Is Incorporated into HIV-1 Virions through Interactions with Viral and Nonviral RNAs*

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• SNP-based identification of miRNA biomarkers associated with major depressive disorder

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• Development of APOBEC3B inhibitors: Recent advances and perspectives.

  2025cites this paper
• Protein‐RNA Docking Benchmark v3.0 Integrated With Binding Affinity

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• Unraveling the Enzyme-Substrate Properties for APOBEC3A-mediated RNA Editing.

  2023cites this paper
• APOBEC3 family proteins as drivers of virus evolution

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• Multiple roles of apolipoprotein B mRNA editing enzyme catalytic subunit 3B (APOBEC3B) in human tumors: a pan-cancer analysis

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  2022cites this paper
• C-to-U RNA Editing: From Computational Detection to Experimental Validation.

  2021cites this paper
• RNA Editing: Methods and Protocols

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  2020cites this paper
• Infectious vaccine-derived rubella viruses emerge, persist, and evolve in cutaneous granulomas of children with primary immunodeficiencies

  2019cites this paper
• Structural Investigations on the Interactions between Cytidine Deaminase Human APOBEC3G and DNA.

  2019cites this paper
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  2019cites this paper
• An Alu Element Insertion in Intron 1 Results in Aberrant Alternative Splicing of APOBEC3G Pre-mRNA in Northern Pig-Tailed Macaques (Macaca leonina) That May Reduce APOBEC3G-Mediated Hypermutation Pressure on HIV-1

  2019cites this paper
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  2019cites this paper
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  2019cites this paper
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  2018cites this paper
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  2018cites this paper
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  2018cites this paper
• Modeling the Embrace of a Mutator: APOBEC Selection of Nucleic Acid Ligands

  2018cites this paper
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  2017influential citation
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  2017cites this paper
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  2017cites this paper
• Nanoscale Characterization of Interaction of APOBEC3G with RNA.

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