Early Intravenous Infusion of Sodium Nitrite Protects Brain Against In Vivo Ischemia-Reperfusion Injury

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Stroke

• Publication date

  2006-11-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1161/01.STR.0000245116.40163.1cPMID 17008610
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Effects of sodium nitrite on ischemia-reperfusion injury in the rat kidney.

  2006cited by this paper
• Cytoprotective effects of nitrite during in vivo ischemia-reperfusion of the heart and liver.

  2005cited by this paper
• Nitrite infusions to prevent delayed cerebral vasospasm in a primate model of subarachnoid hemorrhage.

  2005cited by this paper
• Granulocyte colony-stimulating factor enhances angiogenesis after focal cerebral ischemia.

  2005cited by this paper
• Inhaled nebulized nitrite is a hypoxia-sensitive NO-dependent selective pulmonary vasodilator

  2004cited by this paper
• HMG-CoA Reductase Inhibitor, Atorvastatin, Promotes Sensorimotor Recovery, Suppressing Acute Inflammatory Reaction After Experimental Intracerebral Hemorrhage

  2004cited by this paper
• Reperfusion-Induced Oxidative/Nitrative Injury to Neurovascular Unit After Focal Cerebral Ischemia

  2004cited by this paper
• Nitrite reduction to nitric oxide by deoxyhemoglobin vasodilates the human circulation

  2003cited by this paper
• NO-dependent protein nitration: a cell signaling event or an oxidative inflammatory response?

  2003cited by this paper
• Nitric-oxide

  2002cited by this paper
• Mevastatin, an HMG-CoA reductase inhibitor, reduces stroke damage and upregulates endothelial nitric oxide synthase in mice.

  2001cited by this paper
• Nitrite-derived nitric oxide: a possible mediator of 'acidic-metabolic' vasodilation.

  2001cited by this paper
• A nitric oxide donor induces neurogenesis and reduces functional deficits after stroke in rats

  2001cited by this paper
• Fas-induced caspase denitrosylation.

  1999cited by this paper
• Bright and dark sides of nitric oxide in ischemic brain injury.

  1997cited by this paper
• The role of nitric oxide in the pathophysiology of thromboembolic stroke in the rat.

  1997cited by this paper
• Nitric oxide and apoptosis: another paradigm for the double-edged role of nitric oxide.

  1997cited by this paper
• Superoxide production in rat hippocampal neurons: selective imaging with hydroethidine

  1996cited by this paper
• Nitric oxide signaling in the central nervous system.

  1995cited by this paper
• L-Arginine Infusion Promotes Nitric Oxide-Dependent Vasodilation, Increases Regional Cerebral Blood Flow, and Reduces Infarction Volume in the Rat

  1994cited by this paper
• Nitric Oxide Donors Increase Blood Flow and Reduce Brain Damage in Focal Ischemia: Evidence That Nitric Oxide is Beneficial in the Early Stages of Cerebral Ischemia

  1994cited by this paper
• Antagonistic action of imidazolineoxyl N-oxides against endothelium-derived relaxing factor/.NO through a radical reaction.

  1993cited by this paper
• Mechanisms Involved in the Neuroprotective Activity of a Nitric Oxide Synthase Inhibitor During Focal Cerebral Ischemia

  1993cited by this paper

• Therapeutic potential of nitric oxide and its donors in hemorrhagic and ischemic stroke: a systematic review.

  2026cites this paper
• Targeted Redox Regulation α-Ketoglutarate Dehydrogenase Complex for the Treatment of Human Diseases

  2025cites this paper
• Addressing the “Nitric Oxide Crisis” in Cardiovascular–Kidney–Metabolic Syndrome: Therapeutic Potential of the Inorganic Nitrate–Nitrite–NO Pathway

  2025cites this paper
• Prevention of Metabolic Impairment by Dietary Nitrate in Overweight Male Mice Improves Stroke Outcome

  2025cites this paper
• Content of Nitrogen Monoxide and Copper in the Hippocampus of a Rat Model of Short-Term Cerebral Ischemia Followed by Reperfusion

  2024cites this paper
• HDAC9 Deficiency Upregulates cGMP-dependent Kinase II to Mitigate Neuronal Apoptosis in Ischemic Stroke

  2024cites this paper
• Research progress of prodrugs for the treatment of cerebral ischemia.

  2024cites this paper
• The Role of Nitric oxide in the sweep gas for patients receiving Extracorporeal Membrane Oxygenation or Cardiopulmonary Bypass.

  2024cites this paper
• Investigation of NO Role in Neural Tissue in Brain and Spinal Cord Injury

  2023cites this paper
• Nitric Oxide Production from Nitrite plus Ascorbate during Ischemia upon Hippocampal Glutamate NMDA Receptor Stimulation

  2023cites this paper
• Advances in nitric oxide regulators for the treatment of ischemic stroke.

  2023cites this paper
• Bringing Nitric Oxide to the Molybdenum World—A Personal Perspective

  2023cites this paper
• Nitrite Supplementation Restores Aortic Health in Chronically Stressed Mice

  2023cites this paper
• The Generation of Nitric Oxide from Aldehyde Dehydrogenase-2: The Role of Dietary Nitrates and Their Implication in Cardiovascular Disease Management

  2022cites this paper
• Arterial Glyceryl Trinitrate in Acute Ischemic Stroke after Thrombectomy for Neuroprotection (AGAIN): Rationale, design and protocol for a prospective randomized controlled trial

  2022cites this paper
• Targeting hydrogen sulfide and nitric oxide to repair cardiovascular injury after trauma.

  2022cites this paper
• Dithiol-Activated Bioorthogonal Chemistry for Endoplasmic Re-ticulum-Targeted Synergistic Chemophototherapy.

  2022cites this paper
• Neuroprotective role of nitric oxide inhalation and nitrite in a Neonatal Rat Model of Hypoxic-Ischemic Injury

  2022cites this paper
• Nitrate Metabolism and Ischemic Cerebrovascular Disease: A Narrative Review

  2022cites this paper
• Modulation of oxidative neurometabolism in ischemia/reperfusion by nitrite.

  2022cites this paper
• Effects of inorganic nitrate on ischaemia-reperfusion injury after coronary artery bypass surgery: a randomised controlled trial

  2021cites this paper
• Content of nitric oxide and copper in the olfactory bulbs of the rats brain after modeling of cerebral stroke and intranasal administration of mesenchymal stem cells

  2021cites this paper
• Beneficial Effect of Sodium Nitrite on EEG Ischaemic Markers in Patients with Subarachnoid Haemorrhage

  2021cites this paper
• Protective Effects of Topical Application of Nitrite on Testicular Ischemia-Reperfusion Injury in Rats

  2021influential citation
• The Biologically Relevant Coordination Chemistry of Iron and Nitric Oxide: Electronic Structure and Reactivity.

  2021cites this paper
• The Roles of Dominance of the Nitric Oxide Fractions Nitrate and Nitrite in the Epilepsy-Prone EL Mouse Brain.

  2021cites this paper
• Dietary Inorganic Nitrate Protects Hepatic Ischemia-Reperfusion Injury Through NRF2-Mediated Antioxidative Stress

  2021cites this paper
• Rapid Intravenous Glyceryl Trinitrate in Ischemic Damage (RIGID) After Stroke: Rationale, Design and Protocol for a Prospective Randomized Controlled Trial

  2021cites this paper
• Neuroprotective Treatment of Postanoxic Encephalopathy: A Review of Clinical Evidence

  2021cites this paper
• Design, Synthesis, and Biological Evaluation of Organic Nitrite (NO2-) Donors as Potential Anticerebral Ischemia Agents.

  2021cites this paper
• The Contribution of Small Vessel Disease to Neurodegeneration: Focus on Alzheimer’s Disease, Parkinson’s Disease and Multiple Sclerosis

  2021cites this paper
• Regulation of carbohydrate metabolism by nitric oxide and hydrogen sulfide: Implications in diabetes.

  2020cites this paper
• Nitrite elicits divergent NO-dependent signaling that associates with outcome in out of hospital cardiac arrest

  2020cites this paper
• AMPK, Mitochondrial Function, and Cardiovascular Disease

  2020cites this paper
• Renovascular effects of inorganic nitrate following ischemia-reperfusion of the kidney

  2020cites this paper
• Dietary nitrate reduces blood pressure and cerebral artery velocity fluctuations and improve cerebral autoregulation in transient ischemic attack patients.

  2020cites this paper
• The Noncanonical Pathway for In Vivo Nitric Oxide Generation: The Nitrate-Nitrite-Nitric Oxide Pathway

  2020cites this paper
• Effect of nitrite on neural activity in the healthy brain

  2019cites this paper
• Therapeutic implications of nitrite in hypertension.

  2019cites this paper
• Thymoquinone therapy remediates elevated brain tissue inflammatory mediators induced by chronic administration of food preservatives

  2019cites this paper
• The effect of inorganic nitrate and antiplatelet drugs on NO metabolites and platelet reactivity in patients with stable coronary artery disease

  2019cites this paper
• Mild NO preconditioning protects H9c2 cells against NO-induced apoptosis through activation of PI3K/Akt and PKA-dependent pathways

  2019cites this paper
• Neuroprotective effects of crocin I and II in an ischemia-reperfusion injury model

  2019cites this paper
• Nitrite pharmacokinetics, safety and efficacy after experimental ventricular fibrillation cardiac arrest.

  2019cites this paper
• Neuroprotective Effects and Mechanisms of Zhenlong Xingnao Capsule in In Vivo and In Vitro Models of Hypoxia

  2019cites this paper
• Nitric oxide signalling in the brain and its control of bodily functions

  2019cites this paper
• Effect of nitrite on the electroencephalographic activity in the healthy brain.

  2019cites this paper
• Impacts of Renal Denervation and Vagus Nerve Stimulation on Acute Renal Failure Induced by Renal Ischemia Reperfusion injury in Rat Model

  2019cites this paper
• Small Vessels Are a Big Problem in Neurodegeneration and Neuroprotection

  2019cites this paper
• Sodium Nitrite Attenuates Hepatic Ischemia-Reperfusion Injury in Rats.

  2019cites this paper
• Hydrogen sulfide, nitric oxide, and neurodegenerative disorders

  2018cites this paper
• Putting xanthine oxidoreductase and aldehyde oxidase on the NO metabolism map: Nitrite reduction by molybdoenzymes☆

  2018cites this paper
• Therapeutic value of stimulating the nitrate‐nitrite‐nitric oxide pathway to attenuate oxidative stress and restore nitric oxide bioavailability in cardiorenal disease

  2018cites this paper
• Usefulness of Intravenous Sodium Nitrite During Resuscitation for the Treatment of Out-of-Hospital Cardiac Arrest.

  2018cites this paper
• Sodium nitrite-derived nitric oxide protects rat testes against ischemia/reperfusion injury

  2018cites this paper
• Reduced blood pressure responsiveness to skeletal muscle metaboreflex activation in older adults following inorganic nitrate supplementation.

  2018cites this paper
• The Role of Vasodilator Receptors of Renin–angiotensin System on Nitric Oxide Formation and Kidney Circulation after Angiotensin II Infusion in Renal Ischemia/Reperfusion Rats

  2018cites this paper
• Hemodynamic effects of IV sodium nitrite in hospitalized comatose survivors of out of hospital cardiac arrest.

  2018cites this paper
• Acute oral dose of sodium nitrite causes redox imbalance and DNA damage in rat kidney

  2018cites this paper
• Dietary nitrate supplementation reduces low frequency blood pressure fluctuations in rats following distal middle cerebral artery occlusion.

  2018cites this paper
• A New Methodology for Detection and Assessment of Nitric Oxide in Biological Samples

  2017cites this paper
• The Mitochondrion: A Physiological Target of Nitrite

  2017cites this paper
• Heme Protein Metabolism of NO and Nitrite

  2017cites this paper
• Dietary nitrate attenuates renal ischemia-reperfusion injuries by modulation of immune responses and reduction of oxidative stress

  2017cites this paper
• Effect of sodium nitrite on local control of contracting skeletal muscle microvascular oxygen pressure in healthy rats.

  2017cites this paper
• Динамика основных биохимических показателей сыворотки крови крыс при остром иммобилизационном стрессе после применения мезенхимальных стволовых клеток

  2017cites this paper
• Update on Nitrite Reduction in Ischemic Disease: Mechanisms and Clinical Translation

  2017cites this paper
• Anti-obesity and anti-diabetic effects of nitrate and nitrite.

  2017cites this paper
• Nitrite administration improves sepsis-induced myocardial and mitochondrial dysfunction by modulating stress signal responses

  2017cites this paper
• It is rocket science - why dietary nitrate is hard to 'beet'! Part I: twists and turns in the realization of the nitrate-nitrite-NO pathway.

  2017cites this paper
• Acute beetroot juice supplementation on sympathetic nerve activity: a randomized, double-blind, placebo-controlled proof-of-concept study.

  2017cites this paper
• Dietary nitrate load lowers blood pressure and renal resistive index in patients with chronic kidney disease: A pilot study.

  2017cites this paper
• The Role of ATP-Sensitive Potassium Channels and Nitric Oxide in the Protective Effect of Preconditioning of the Brain

  2017cites this paper
• Methane bioactivity and interactions with other biological gases

  2017cites this paper
• The Neuroprotective Effect of Sodium Nitrite on Ischemic Stroke-Induced Mitochondrial Dysfunction via Downregulation of Intrinsic Apoptosis Pathway

  2017cites this paper
• The macrophage stimulating anti-cancer agent, RRx-001, protects against ischemia-reperfusion injury

  2017cites this paper
• The Medicinal Chemistry of Nitrite as a Source of Nitric Oxide Signaling.

  2017cites this paper
• Mining Natural Products for Cardiovascular Benefits Acute beetroot juice supplementation on sympathetic nerve activity : a randomized , double-blind , placebo-controlled proof-of-concept study

  2017cites this paper
• Differential mitochondrial dinitrosyliron complex formation by nitrite and nitric oxide

  2017cites this paper
• Molecular Bases of Brain Preconditioning

  2017cites this paper
• Changes of Nitric Oxide Content in the Rat Hippocampus, Heart and Liver in Acute Phase of Ischemia

  2016cites this paper
• Neuroprotective effect of nitrite-derived NO in brain injury mediated through the NOS-independent but not the GC/COX/xanthine oxidase/PGIS-dependent pathways

  2016cites this paper
• Sodium nitrite impacts the peripheral control of contracting skeletal muscle microvascular oxygen pressure in healthy rats

  2016cites this paper
• Preconditioning is hormesis part I: Documentation, dose-response features and mechanistic foundations.

  2016cites this paper
• Nitrite Reduces Ischemia-Induced Ventricular Arrhythmias by Attenuating Connexin 43 Dephosphorylation in Rats

  2016cites this paper
• [The role of ATP-dependent potassium channels and nitric oxide system in the neuroprotective effect of preconditioning].

  2016cites this paper
• Therapeutic effects of inorganic nitrate and nitrite in cardiovascular and metabolic diseases

  2016cites this paper
• Investigating the mechanisms of nitrite-mediated cardioprotection

  2016cites this paper
• Is Nitric Oxide Assuming a Janus-Face in The Central Nervous System?

  2016cites this paper
• To Be-et, or Not to Be-et, That is the Question: The Role(s) of Nitrate and Nitrite in Health and Illness.

  2016cites this paper
• Why Part I: Twists and Turns in the Realisation of the Nitrate-Nitrite-NO Pathway

  2016cites this paper
• Inhibition of myeloperoxidase-mediated oxidative damage by nitrite in SH-SY5Y cells: Relevance to neuroprotection in neurodegenerative diseases.

  2016cites this paper
• Peritoneal dialysis impairs nitric oxide homeostasis and may predispose infants with low systolic blood pressure to cerebral ischemia.

  2016cites this paper
• Dietary Nitrate and the Epidemiology of Cardiovascular Disease: Report From a National Heart, Lung, and Blood Institute Workshop

  2016cites this paper
• It is Rocket Science – Why Dietary Nitrate is Hard to Beet! Part I: Twists and Turns in the Realisation of the Nitrate-Nitrite-NO Pathway

  2016cites this paper
• Molecular Dissection of Renal Ischemia-Reperfusion: Oxidative Stress and Cellular Events.

  2016cites this paper
• Dietary Nitrate, Nitric Oxide, and Cardiovascular Health

  2016cites this paper
• The cytoprotective effect of nitrite is based on the formation of dinitrosyl iron complexes.

  2015cites this paper
• Dietary intake and bio-activation of nitrite and nitrate in newborn infants

  2015cites this paper
• agingnitrite supplementation for healthy arterial

  2015cites this paper