Alarming dendritic cells for Th2 induction

There is an ever-increasing understanding of the mechanisms by which pathogens such as bacteria, viruses, and protozoa activate dendritic cells (DCs) to drive T helper type 1 (Th1) responses, but we know much less about how these cells elicit Th2 responses. This gap in our knowledge puts us at a distinct disadvantage in designing therapeutics for certain immune-mediated diseases. However, progress is being made with the identification of novel endogenous tissue factors that can enhance Th2 induction by DCs.

• Publication year

  2008

• Venue

  Journal of Experimental Medicine

• Publication date

  2008-01-21

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1084/jem.20072665PMID 18195077PMCID 2234366
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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