Acquired dysfunction due to the circulation of "exhausted" platelets.

No abstract is available for this paper.

• Publication year

  1980

• Venue

  American Journal of Medicine

• Publication date

  1980-08-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1016/0002-9343(80)90383-6PMID 7405945
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• "Exhausted" platelets continue to circulate.

  1978cited by this paper
• The hemolytic-uremic syndrome is a syndrome.

  1978cited by this paper
• Thrombocytopathy associated with autoimmune haemolytic anaemia.

  1978cited by this paper
• Adenine nucleotides in thrombin-degranulated platelets: effect of prolonged circulation in vivo.

  1977cited by this paper
• Acquired storage pool disease in platelets during disseminated intravascular coagulation.

  1976cited by this paper
• In Vitro and in Vivo Functions of Thrombin-Treated Platelets

  1976cited by this paper
• The Prothrombin Time Test: Effect of Varying Citrate Concentration

  1976cited by this paper
• Rapid, Sensitive Microassay for Platelet 5HT

  1974cited by this paper
• Letter: Rapid, sensitive microassay for platelet 5HT.

  1974cited by this paper
• Platelet function and coagulation profile in lupus erythematosus. Studies in 50 patients.

  1974cited by this paper
• Nucleotide and serotonin metabolism in platelets with defective secondary aggregation.

  1974cited by this paper
• Acquired "storage pool disease" of platelets associated with circulating antiplatelet antibodies.

  1974cited by this paper
• Effect of Repeated Treatment of Rabbit Platelets with Low Concentrations of Thrombin on their Function, Metabolism and Survival

  1973cited by this paper
• Observations on the Mechanism of the Haematological Changes in the Haemolytic Uraemic Syndrome of Infancy

  1972cited by this paper
• The bleeding time as a screening test for evaluation of platelet function.

  1972cited by this paper
• Human blood coagulation, haemostasis and thrombosis;

  1972cited by this paper
• Platelet and fibrinogen consumption in man.

  1972cited by this paper
• Studies of platelets in a variant of the Hermansky-Pudlak syndrome.

  1971cited by this paper
• HUMAN RENAL ALLOGRAFTS: The Role of Vascular Injury in Early Graft Failure

  1971cited by this paper
• MECHANISMS OF IMMUNOLOGICAL INJURY DURING ANTIBODY-MEDIATED HYPERACUTE REJECTION OF RENAL HETEROGRAFTS

  1971cited by this paper
• Human renal allografts. Glomerular deposits of horse immunoglobulin G and nephritis following administration of antilymphocyte globulin.

  1971cited by this paper
• Hereditary Defect in the Platelet Release Reaction Caused by a Deficiency in the Storage Pool of Platelet Adenine Nucleotides

  1970cited by this paper
• Milestone in Dermatology

  1968cited by this paper

• Platelet function abnormalities in acquired hemophilia A

  2025cites this paper
• Idiopathic Mild Platelet Dysfunction: Baseline Characteristics and Clinical Courses

  2025cites this paper
• Platelets in Hemostasis, Thrombosis, and Inflammation After Major Trauma

  2024cites this paper
• High-Dimensional Single-Cell Mass Cytometry Demonstrates Differential Platelet Functional Phenotypes in Infants With Congenital Heart Disease

  2024cites this paper
• Mitochondrial dysfunction in platelets from severe trauma patients - A prospective case-control study.

  2024cites this paper
• The Diagnostic Assessment of Platelet Function Defects - Part 2: Update on Platelet Disorders

  2024cites this paper
• Role of single-dose intravenous iron therapy for the treatment of anaemia after orthopaedic trauma: protocol for a pilot randomised controlled trial

  2023cites this paper
• Pulmonary hypertension: An unexplored risk factor for stroke in patients with atrial fibrillation.

  2023cites this paper
• Challenges in Platelet Functions in HIV/AIDS Management

  2023cites this paper
• Effects of the circulating environment of COVID-19 on platelet and neutrophil behavior

  2023cites this paper
• What can we learn from senescent platelets, their transcriptomes and proteomes?

  2023cites this paper
• Prospective evaluation of platelet function and fibrinolysis in 20 dogs with trauma.

  2023cites this paper
• Detection of cellular traction forces via the force-triggered Cas12a-mediated catalytic cleavage of a fluorogenic reporter strand

  2023cites this paper
• A Critical Reappraisal of the Bleeding Time

  2023cites this paper
• Laboratory-based inequity in thrombosis and hemostasis: review of the evidence.

  2023cites this paper
• Contemporary tools for evaluation of hemostasis in neonates. Where are we and where are we headed?

  2023cites this paper
• Release of MMP-2 in the circulation of patients with acute coronary syndromes undergoing percutaneous coronary intervention: Role of platelets.

  2022cites this paper
• "Importance of catecholamine signaling in the development of platelet exhaustion after traumatic injury": Comment

  2022cites this paper
• Traumatic brain injury patients with platelet inhibition receiving platelet transfusion demonstrate decreased need for neurosurgical intervention and decreased mortality

  2022cites this paper
• Importance of catecholamine signaling in the development of platelet exhaustion after traumatic injury

  2022cites this paper
• The level of serotonin and its metabolite in hemolytic-uremic syndrome in children

  2022cites this paper
• “Importance of catecholamine signaling in the development of platelet exhaustion after traumatic injury”: Reply

  2022cites this paper
• Platelet reactivity and platelet count in women with iron deficiency treated with intravenous iron

  2022cites this paper
• Early SARS-CoV-2 infection: Platelet-neutrophil complexes and platelet function

  2022cites this paper
• Postinjury platelet aggregation and venous thromboembolism

  2022cites this paper
• Chronic Immune Platelet Activation Is Followed by Platelet Refractoriness and Impaired Contractility

  2022cites this paper
• Variation of platelet function in clinical phenotypes of acute venous thromboembolism – Results from the GMP‐VTE project

  2021cites this paper
• Assessment of Platelet Thrombus Formation under Flow Conditions in Adult Patients with COVID-19: An Observational Study

  2021cites this paper
• Good Platelets Gone Bad: The Effects of Trauma Patient Plasma on Healthy Platelet Aggregation.

  2020cites this paper
• Qualitative disorders of platelets and vasculature

  2020cites this paper
• Identification of injury and shock driven effects on ex vivo platelet aggregometry: A cautionary tale of phenotyping

  2020cites this paper
• Platelets and Fibrinogen: Emerging Complexity in Trauma-Induced Coagulopathy

  2020cites this paper
• Coagulation Profiles of Pulmonary Arterial Hypertension Patients, Assessed by Non-Conventional Hemostatic Tests and Markers of Platelet Activation and Endothelial Dysfunction

  2020cites this paper
• D-Dimer and Fibrin Degradation Products Impair Platelet Signaling: Plasma D-Dimer Is a Predictor and Mediator of Platelet Dysfunction During Trauma.

  2020cites this paper
• Immunothrombotic Dysregulation in COVID-19 Pneumonia Is Associated With Respiratory Failure and Coagulopathy

  2020cites this paper
• Intensive Care for Emergency Surgeons

  2019cites this paper
• Spontaneous and induced platelet aggregation in apparently healthy subjects in relation to age

  2019cites this paper
• Disseminated intravascular coagulation in cardiac arrest and resuscitation

  2019cites this paper
• Activation, function and content of platelets in burn patients

  2019cites this paper
• Understanding Platelets in Infectious and Allergic Lung Diseases

  2019cites this paper
• Acquired Glanzmann thrombasthenia: From antibodies to anti-platelet drugs.

  2019cites this paper
• Coagulation Derangements in the ACS Patient: Understanding and Addressing Acute Coagulopathy

  2019cites this paper
• Platelets retain inducible alpha granule secretion by P‐selectin expression but exhibit mechanical dysfunction during trauma‐induced coagulopathy

  2019cites this paper
• Acquired Disorders of Platelet Function

  2019cites this paper
• Pharmacological strategies for targeting platelet activation in asthma.

  2019cites this paper
• Investigation into the mechanisms of platelet recruitment and migration during allergic inflammation

  2018cites this paper
• Different resuscitation strategies and novel pharmacologic treatment with valproic acid in traumatic brain injury

  2018cites this paper
• Trauma-Associated Coagulopathy

  2018cites this paper
• Platelet and coagulation disorders in newly diagnosed patients with pulmonary arterial hypertension.

  2018cites this paper
• Valproic acid modulates platelet and coagulation function ex vivo

  2017cites this paper
• Is Coagulopathy an Appropriate Therapeutic Target During Critical Illness Such as Trauma or Sepsis?

  2017cites this paper
• Adenosine diphosphate platelet dysfunction on thromboelastogram is independently associated with increased morality in traumatic brain injury

  2017cites this paper
• Fibrinolysis shutdown is associated with a fivefold increase in mortality in trauma patients lacking hypersensitivity to tissue plasminogen activator

  2017cites this paper
• Traditional and pharmacologic resuscitation in traumatic brain injury: targeting inflammatory and hemostatic pathways

  2017cites this paper
• Thromboelastography with Platelet Mapping as an Alternative for the Platelet Function Assay-100 in Detecting Clopidogrel in Trauma Patients

  2017cites this paper
• Acute effects of 30 minutes of exposure to a smartphone call on in vitro platelet function.

  2017cites this paper
• Acute traumatic coagulopathy: The elephant in a room of blind scientists

  2017cites this paper
• Platelet aggregation after blunt trauma is associated with the acute respiratory distress syndrome and altered by cigarette smoke exposure

  2017cites this paper
• Platelet adenosine diphosphate inhibition in trauma patients by thromboelastography correlates with paradoxical increase in platelet dense granule content by flow cytometry.

  2016cites this paper
• Utility of the Aspirin and P2Y12 Response Assays to Determine the Effect of Antiplatelet Agents on Platelet Reactivity in Traumatic Brain Injury

  2016cites this paper
• Use of Aspirin and P2Y12 Response Assays in Detecting Reversal of Platelet Inhibition With Platelet Transfusion in Patients With Traumatic Brain Injury on Antiplatelet Therapy

  2016cites this paper
• Platelet Aggregation Study in Patients With Hemoglobin Eβ Thalassemia in India

  2016cites this paper
• Validation of acute traumatic coagulopathy in an ovine model of trauma and haemorrhage

  2016cites this paper
• Assessment of hemostatic changes in a model of acute hemorrhage in dogs.

  2016cites this paper
• Platelet closure time in anesthetized Greyhounds with hemorrhagic shock treated with hydroxyethyl starch 130/0.4 or 0.9% sodium chloride infusions.

  2016cites this paper
• Advances in the understanding of trauma-induced coagulopathy.

  2016cites this paper
• Inhibition of platelet function is common following even minor injury

  2016cites this paper
• Platelet mitochondrial dysfunction in critically ill patients: comparison between sepsis and cardiogenic shock

  2015cites this paper
• Traumatic brain injury causes platelet adenosine diphosphate and arachidonic acid receptor inhibition independent of hemorrhagic shock in humans and rats

  2014cites this paper
• Early Platelet Dysfunction in a Rodent Model of Blunt Traumatic Brain Injury Reflects the Acute Traumatic Coagulopathy Found in Humans

  2014cites this paper
• The Effect of hydroxyethyl starch 130/0.4 on canine platelet function

  2014cites this paper
• Treatment with a histone deacetylase inhibitor, valproic acid, is associated with increased platelet activation in a large animal model of traumatic brain injury and hemorrhagic shock.

  2014cites this paper
• Platelets and allergic inflammation

  2014cites this paper
• Elevated platelet count, C-reactive protein and thromboxane analog-induced platelet aggregation in patients with Gulf War veterans’ illnesses: evidence of a chronic inflammatory state?

  2013cites this paper
• Acquired Disorders of Platelet Function

  2013cites this paper
• EVALUACIÓN DE LA HEMOSTASIA EN PERROS DE RAZA BEAGLE INFECTADOS EXPERIMENTALMENTE CON UNA CEPA DE ANAPLASMA PLATYS

  2013cites this paper
• Platelet Dysfunction is an Early Marker for Traumatic Brain Injury-Induced Coagulopathy

  2013cites this paper
• Infection-associated platelet dysfunction of canine platelets detected in a flow chamber model

  2013cites this paper
• Early platelet dysfunction: an unrecognized role in the acute coagulopathy of trauma.

  2012cites this paper
• Hemoptise relacionada ao uso de clopidogrel em regime ambulatorial

  2010cites this paper
• Increased platelet glycoprotein Ib receptor number, enhanced platelet adhesion and severe cerebral ischaemia in a patient with polycythaemia vera

  2009influential citation
• Thrombotic thrombocytopenic purpura in 2 siblings: defective platelet function and plasma factor deficiency occurring simultaneously.

  2009cites this paper
• [Role of blood platelets in microcirculatory disorders].

  2008cites this paper
• [Differential therapy of thrombotic-thrombopenic purpura. Administration of fresh plasma versus plasma separation].

  2008cites this paper
• Aspirin-induced platelet inhibition in patients undergoing cardiac surgery

  2007cites this paper
• CHAPTER 58 – Acquired Disorders of Platelet Function

  2007cites this paper
• Defining a role for platelets in allergic inflammation.

  2007cites this paper
• Acquired platelet dysfunction.

  2007cites this paper
• Platelet Activation During Allergic Inflammation

  2007cites this paper
• Novel uses for anti‐platelet agents as anti‐inflammatory drugs

  2007influential citation
• Defective platelet beta-N-acetyl hexosaminidase content and release in chronic myeloproliferative disorders.

  2006cites this paper
• Defective platelet β-N-acetyl hexosaminidase content and release in chronic myeloproliferative disorders

  2006cites this paper
• Hemostatic studies in patients with infective endocarditis: a report on nine consecutive cases with evidence of coagulopathy

  2005cites this paper
• Primary dysfunction in aggregation and secretion of SHRSP platelets: Not secondary to the circulation of “exhausted” platelets

  2004cites this paper
• [Disseminated intravascular coagulation].

  2004cites this paper
• In vivo Platelet Activation and Hyperaggregation in Hemoglobin E/β-Thalassemia: A Consequence of Splenectomy

  2003cites this paper
• Protective role of nitric oxide in mice with Shiga toxin-induced hemolytic uremic syndrome.

  2002cites this paper
• Platelet functions in patients with meningococcal meningitis at the Kenyatta National Hospital, Nairobi.

  2002influential citation
• Non-haematological functions of platelets.

  2002cites this paper
• In vivo characterization of Lopap, a prothrombin activator serine protease from the Lonomia obliqua caterpillar venom.

  2001cites this paper