A critical role for cortactin phosphorylation by Abl-family kinases in PDGF-induced dorsal-wave formation.

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Current Biology

• Publication date

  2007-03-06

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/J.CUB.2007.01.057PMID 17306540
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2003influential reference
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• Inhibition of Cell Migration by Abl Family Tyrosine Kinases through Uncoupling of Crk-CAS Complexes*

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• Profilin and the Abl tyrosine kinase are required for motor axon outgrowth in the Drosophila embryo.

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• The BCR/ABL oncogene alters the chemotactic response to stromal-derived factor-1alpha.

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• c-Abl is activated by growth factors and Src family kinases and has a role in the cellular response to PDGF.

  1999influential reference
• Growth Factor-dependent Phosphorylation of the Actin-binding Protein Cortactin Is Mediated by the Cytoplasmic Tyrosine Kinase FER*

  1998cited by this paper
• Essential roles for the Abl and Arg tyrosine kinases in neurulation.

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• The Role of Tyrosine Phosphorylation of Cortactin in the Locomotion of Endothelial Cells*

  1998cited by this paper
• Overexpression of EMS1/cortactin in NIH3T3 fibroblasts causes increased cell motility and invasion in vitro

  1998cited by this paper
• BCR/ABL induces multiple abnormalities of cytoskeletal function.

  1997cited by this paper
• BCR-ABL gene variants.

  1997cited by this paper
• Inhibition of the Abl protein-tyrosine kinase in vitro and in vivo by a 2-phenylaminopyrimidine derivative.

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• The involvement of the chromosome 11q13 region in human malignancies: cyclin D1 and EMS1 are two new candidate oncogenes--a review.

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• Specific and redundant roles of Src and Fyn in organizing the cytoskeleton

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• c‐Abl kinase regulates the protein binding activity of c‐Crk.

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• Identification and characterization of a novel cytoskeleton-associated pp60src substrate

  1991cited by this paper
• Isolation and characterization of a novel human gene expressed specifically in the cells of hematopoietic lineage.

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• The repeat region of cortactin is intrinsically disordered in solution

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• Cortactin: Cell Functions of A Multifaceted Actin-Binding Protein.

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• Corticosteroid‐induced dendrite loss and behavioral deficiencies can be blocked by activation of Abl2/Arg kinase

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