Microglia activation in the hypothalamic PVN following myocardial infarction.

No abstract is available for this paper.

• Publication year

  2010

• Venue

  Brain Research

• Publication date

  2010-04-22

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.brainres.2010.02.028PMID 20156424
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2008cited by this paper
• Effects of a Rho kinase inhibitor on pressure overload induced cardiac hypertrophy and associated diastolic dysfunction.

  2008cited by this paper
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  2008cited by this paper
• Inhibition of brain proinflammatory cytokine synthesis reduces hypothalamic excitation in rats with ischemia-induced heart failure.

  2008cited by this paper
• Microglial activation and TNFα production mediate altered CNS excitability following peripheral inflammation

  2008cited by this paper
• TNF-α blockade decreases oxidative stress in the paraventricular nucleus and attenuates sympathoexcitation in heart failure rats

  2007cited by this paper
• Increased interleukin-6 receptor expression in the paraventricular nucleus of rats with heart failure.

  2007cited by this paper
• TNF-alpha blockade decreases oxidative stress in the paraventricular nucleus and attenuates sympathoexcitation in heart failure rats.

  2007cited by this paper
• Modulation of microglial pro-inflammatory and neurotoxic activity for the treatment of Parkinson’s disease

  2006cited by this paper
• Role of cytokines in inflammatory process in Parkinson's disease.

  2006cited by this paper
• Post-infarction ventricular remodeling: an array of molecular events.

  2005cited by this paper
• Pathophysiological roles of extracellular nucleotides in glial cells: differential expression of purinergic receptors in resting and activated microglia.

  2005cited by this paper
• Resting Microglial Cells Are Highly Dynamic Surveillants of Brain Parenchyma in Vivo

  2005cited by this paper
• ATP mediates rapid microglial response to local brain injury in vivo

  2005cited by this paper
• Disruption of the blood–brain barrier during TNBS colitis

  2005cited by this paper
• Stimulation of Microglial Metabotropic Glutamate Receptor mGlu2 Triggers Tumor Necrosis Factor α-Induced Neurotoxicity in Concert with Microglial-Derived Fas Ligand

  2005cited by this paper
• Acute myocardial infarction induces hypothalamic cytokine synthesis.

  2004influential reference
• Heterogeneity and potentiation of AMPA type of glutamate receptors in rat cultured microglia

  2004cited by this paper
• Neural regulation of the proinflammatory cytokine response to acute myocardial infarction.

  2004influential reference
• Superoxide Is Involved in the Central Nervous System Activation and Sympathoexcitation of Myocardial Infarction–Induced Heart Failure

  2004cited by this paper
• Pharmacological Modulation of Cardiovascular Remodeling: A Guide to Heart Failure Therapy

  2003cited by this paper
• P2X4 receptors induced in spinal microglia gate tactile allodynia after nerve injury

  2003cited by this paper
• Production and neuroprotective functions of fractalkine in the central nervous system.

  2003cited by this paper
• Heart failure and the brain: new perspectives.

  2003influential reference
• Activation of group II metabotropic glutamate receptors underlies microglial reactivity and neurotoxicity following stimulation with chromogranin A, a peptide up‐regulated in Alzheimer's disease

  2002cited by this paper
• World Wide Web at:

  2001cited by this paper
• IFN-gamma production by antigen-presenting cells: mechanisms emerge.

  2001cited by this paper
• IFN-γ production by antigen-presenting cells: mechanisms emerge

  2001cited by this paper
• Dynamics of microglial activation: A confocal time‐lapse analysis in hippocampal slices

  2001cited by this paper
• Microglia: activation and their significance in the central nervous system.

  2001cited by this paper
• Regional Difference in Susceptibility to Lipopolysaccharide-Induced Neurotoxicity in the Rat Brain: Role of Microglia

  2000cited by this paper
• High levels of plasma brain natriuretic peptide and interleukin-6 after optimized treatment for heart failure are independent risk factors for morbidity and mortality in patients with congestive heart failure.

  2000influential reference
• Plasma Cytokine Parameters and Mortality in Patients With Chronic Heart Failure

  2000influential reference
• Role of Paraventricular Nucleus in Mediating Sympathetic Outflow in Heart Failure

  2000cited by this paper
• Extracellular ATP triggers tumor necrosis factor-alpha release from rat microglia.

  2000cited by this paper
• Neuronal expression of Fos protein in the hypothalamus of rats with heart failure.

  2000cited by this paper
• Prognostic value of serum cytokines in patients with congestive heart failure.

  2000influential reference
• Extracellular ATP Triggers Tumor Necrosis Factor‐α Release from Rat Microglia

  2000cited by this paper
• Mechanisms and models in heart failure: A combinatorial approach.

  1999cited by this paper
• Microglial motility in the rat facial nucleus following peripheral axotomy

  1999cited by this paper
• Molecular mechanisms of myocardial remodeling.

  1999cited by this paper
• Interleukin-6 spillover in the peripheral circulation increases with the severity of heart failure, and the high plasma level of interleukin-6 is an important prognostic predictor in patients with congestive heart failure.

  1998influential reference
• Neurons in the hypothalamic paraventricular nucleus send collaterals to the spinal cord and to the rostral ventrolateral medulla in the rat.

  1998cited by this paper
• Loss of inhibitory synapses on the soma and axon initial segment of pyramidal cells in human epileptic peritumoural neocortex: implications for epilepsy.

  1997cited by this paper
• Tumor necrosis factor-alpha and tumor necrosis factor receptors in the failing human heart.

  1996cited by this paper
• Proinflammatory cytokine levels in patients with depressed left ventricular ejection fraction: a report from the Studies of Left Ventricular Dysfunction (SOLVD).

  1996cited by this paper
• Tumor Necrosis Factor-α and Tumor Necrosis Factor Receptors in the Failing Human Heart

  1996cited by this paper
• Selective induction of interleukin-6 in mouse microglia by granulocyte-macrophage colony-stimulating factor

  1996cited by this paper
• Glial cytokines in Alzheimer's disease: review and pathogenic implications.

  1995cited by this paper
• Adverse consequences of high sympathetic nervous activity in the failing human heart.

  1995cited by this paper
• Expression of cytokines during glial differentiation.

  1994cited by this paper
• Reactive cell proliferation and microglia following injury to the rat brain

  1994cited by this paper
• Alterations in brain hexokinase activity associated with heart failure in rats.

  1993cited by this paper
• Elevated circulating levels of tumor necrosis factor in severe chronic heart failure.

  1990influential reference
• Production of tumor necrosis factor-alpha by microglia and astrocytes in culture.

  1989cited by this paper
• Recommendations for quantitation of the left ventricle by two-dimensional echocardiography. American Society of Echocardiography Committee on Standards, Subcommittee on Quantitation of Two-Dimensional Echocardiograms.

  1989cited by this paper
• Functional plasticity of microglia: A review

  1988cited by this paper
• Response of endogenous glial cells to motor neuron degeneration induced by toxic ricin

  1988cited by this paper
• Neurohormonal interactions and adaptations in congestive heart failure.

  1988cited by this paper
• Production of superoxide anions by a CNS macrophage, the microglia

  1987influential reference
• Survival after an experimental myocardial infarction: beneficial effects of long-term therapy with captopril.

  1985cited by this paper
• Hypothalamic integration: organization of the paraventricular and supraoptic nuclei.

  1983cited by this paper

• La régulation neuro-inflammatoire post-infarctus : de la réparation du myocarde à la vulnérabilité arythmogène

  2026cites this paper
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  2026cites this paper
• The effect of acute cardiovascular events on the risk of depression: What groups are vulnerable? Case-control study based on German health claims data.

  2025cites this paper
• Neural Inflammation in Thoracic Dorsal Root Ganglia Mediates Cardiopulmonary Spinal Afferent Sensitization in Chronic Heart Failure

  2025cites this paper
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  2025cites this paper
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  2025cites this paper
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  2025cites this paper
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  2025cites this paper
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  2024cites this paper
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  2024cites this paper
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  2024cites this paper
• Neuroimmune cross-talk in heart failure.

  2024cites this paper
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  2024cites this paper
• Neuroimmunology of Cardiovascular Disease

  2024cites this paper
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  2023cites this paper
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  2023cites this paper
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  2023cites this paper
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  2023cites this paper
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  2023cites this paper
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  2022cites this paper
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  2022cites this paper
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  2022cites this paper
• Probiotics: Protecting Our Health from the Gut

  2022influential citation
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  2022cites this paper
• Nerve-macrophage interactions in cardiovascular disease.

  2021cites this paper
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  2021cites this paper
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  2021cites this paper
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  2021cites this paper
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  2021cites this paper
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  2021cites this paper
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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
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  2019cites this paper
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  2019cites this paper
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  2019cites this paper
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  2018cites this paper
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  2018cites this paper
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  2018cites this paper
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  2018cites this paper
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  2018cites this paper
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  2018cites this paper
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  2017cites this paper
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  2017influential citation
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  2017cites this paper
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  2016cites this paper
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  2016cites this paper
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  2016cites this paper
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  2016cites this paper
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  2016cites this paper
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  2016cites this paper
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  2015cites this paper
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  2015cites this paper
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  2015cites this paper
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  2015cites this paper
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  2015cites this paper
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  2015cites this paper
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  2014cites this paper
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  2014cites this paper
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  2014cites this paper
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  2013cites this paper
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  2013cites this paper
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  2013cites this paper
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  2013cites this paper
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  2013cites this paper
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  2013influential citation
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  2013cites this paper
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  2012cites this paper
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  2012cites this paper
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  2012cites this paper
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  2012influential citation
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  2012cites this paper
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  2011cites this paper
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  2011cites this paper
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  2011cites this paper
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  2011cites this paper
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  2010cites this paper