Ammonia Mediates Methamphetamine-Induced Increases in Glutamate and Excitotoxicity

No abstract is available for this paper.

• Publication year

  2014

• Venue

  Neuropsychopharmacology

• Publication date

  2014-03-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1038/npp.2013.306PMID 24165886PMCID PMC3924538
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Peripheral Ammonia as a Mediator of Methamphetamine Neurotoxicity

  2012cited by this paper
• Decreased dopamine activity predicts relapse in methamphetamine abusers

  2011cited by this paper
• Lactulose: production, purification and potential applications.

  2011cited by this paper
• Wallerian-like axonal degeneration in the optic nerve after excitotoxic retinal insult: an ultrastructural study

  2010cited by this paper
• Acute methamphetamine intoxication: brain hyperthermia, blood-brain barrier, brain edema, and morphological cell abnormalities.

  2009cited by this paper
• Real‐time visualization of cytoplasmic calpain activation and calcium deregulation in acute glutamate excitotoxicity

  2009cited by this paper
• A review of the clinical pharmacology of methamphetamine.

  2009cited by this paper
• Ammonia triggers exocytotic release of L‐glutamate from cultured rat astrocytes

  2009cited by this paper
• Current trends in the treatment of hepatic encephalopathy

  2009cited by this paper
• Glutamate forward and reverse transport: From molecular mechanism to transporter‐mediated release after ischemia

  2008cited by this paper
• Control of acute, chronic, and constitutive hyperammonemia by wild‐type and genetically engineered Lactobacillus plantarum in rodents

  2008cited by this paper
• The Role of Oxidative Stress, Metabolic Compromise, and Inflammation in Neuronal Injury Produced by Amphetamine-Related Drugs of Abuse

  2008cited by this paper
• Two Distinct Modes of Hypoosmotic Medium-Induced Release of Excitatory Amino Acids and Taurine in the Rat Brain In Vivo

  2008cited by this paper
• Interactions between methamphetamine and environmental stress: role of oxidative stress, glutamate and mitochondrial dysfunction.

  2007cited by this paper
• Inflammation and hepatic encephalopathy: Ibuprofen restores learning ability in rats with portacaval shunts

  2007cited by this paper
• Reversible inhibition of mammalian glutamine synthetase by tyrosine nitration

  2007cited by this paper
• Cognitive function and nigrostriatal markers in abstinent methamphetamine abusers

  2006cited by this paper
• The prevalence of psychotic symptoms among methamphetamine users.

  2006cited by this paper
• Reflection impulsivity in current and former substance users.

  2006cited by this paper
• Methamphetamine‐induced spectrin proteolysis in the rat striatum

  2006cited by this paper
• Cognitive function and nigrostriatal markers in abstinent methamphetamine abusers

  2006cited by this paper
• In vivo regulation of extracellular dopamine in the neostriatum: influence of impulse activity and local excitatory amino acids

  2005cited by this paper
• Disparity in the temporal appearance of methamphetamine-induced apoptosis and depletion of dopamine terminal markers in the striatum of mice.

  2005cited by this paper
• Comparison of probiotics and lactulose in the treatment of minimal hepatic encephalopathy in rats.

  2005cited by this paper
• High-Dose Methamphetamine Acutely Activates the Striatonigral Pathway to Increase Striatal Glutamate and Mediate Long-Term Dopamine Toxicity

  2004cited by this paper
• Effects of Activation of NMDA and AMPA Glutamate Receptors on the Extracellular Concentrations of Dopamine, Acetylcholine, and GABA in Striatum of the Awake Rat: A Microdialysis Study

  2003cited by this paper
• Glutamine synthetase activity and glutamine content in brain: modulation by NMDA receptors and nitric oxide.

  2003cited by this paper
• The calpain system.

  2003cited by this paper
• Increased Extracellular Brain Glutamate in Acute Liver Failure: Decreased Uptake or Increased Release?

  2002cited by this paper
• Accumulation of non-erythroid alpha II-spectrin and calpain-cleaved alpha II-spectrin breakdown products in cerebrospinal fluid after traumatic brain injury in rats.

  2001cited by this paper
• Glutamate uptake.

  2001cited by this paper
• Accumulation of non‐erythroid αII‐spectrin and calpain‐cleaved αII‐spectrin breakdown products in cerebrospinal fluid after traumatic brain injury in rats

  2001cited by this paper
• Cognitive Performance of Current Methamphetamine and Cocaine Abusers

  2001cited by this paper
• Association of dopamine transporter reduction with psychomotor impairment in methamphetamine abusers.

  2001cited by this paper
• Effects of ammonia on glutamate transporter (GLAST) protein and mRNA in cultured rat cortical astrocytes.

  2000cited by this paper
• Effect of Temperature on Dopamine Transporter Function and Intracellular Accumulation of Methamphetamine: Implications for Methamphetamine-Induced Dopaminergic Neurotoxicity

  2000cited by this paper
• The Effects of Methamphetamine on Serotonin Transporter Activity

  2000cited by this paper
• Estimating intracellular calcium concentrations and buffering without wavelength ratioing.

  2000cited by this paper
• Evidence for an Astrocytic Glutamate Transporter Deficit in Hepatic Encephalopathy

  1999influential reference
• Differential expression of glutamate receptors by the dopaminergic neurons of the primate striatum.

  1999cited by this paper
• Dissociable Deficits in the Decision-Making Cognition of Chronic Amphetamine Abusers, Opiate Abusers, Patients with Focal Damage to Prefrontal Cortex, and Tryptophan-Depleted Normal Volunteers: Evidence for Monoaminergic Mechanisms

  1999cited by this paper
• Reduced Striatal Dopamine Transporter Density in Abstinent Methamphetamine and Methcathinone Users: Evidence from Positron Emission Tomography Studies with [11C]WIN-35,428

  1998cited by this paper
• Superoxide production and antioxidant enzymes in ammonia intoxication in rats.

  1997cited by this paper
• Effect of methamphetamine on glutamate‐positive neurons in the adult and developing rat somatosensory cortex

  1996cited by this paper
• Methamphetamine-induced hyperthermia and dopaminergic neurotoxicity in mice: pharmacological profile of protective and nonprotective agents.

  1995cited by this paper
• Methamphetamine‐induced neurotoxicity: Roles for glutamate and dopamine efflux

  1994cited by this paper
• Effects of repeated administration of a high dose of methamphetamine on dopamine and glutamate release in rat striatum and nucleus accumbens.

  1994cited by this paper
• Further studies of the role of hyperthermia in methamphetamine neurotoxicity.

  1994cited by this paper
• Neurotoxicity profiles of substituted amphetamines in the C57BL/6J mouse.

  1994influential reference
• The effect of oral‐administered lactulose on colonic nitrogen metabolism and excretion

  1992cited by this paper
• The N-methyl-D-aspartate antagonist MK-801 protects against serotonin depletions induced by methamphetamine, 3,4-methylenedioxymethamphetamine and p-chloroamphetamine.

  1992cited by this paper
• Methamphetamine neurotoxicity and striatal glutamate release: comparison to 3,4-methylenedioxymethamphetamine.

  1992cited by this paper
• The influence of environmental temperature on the transient effects of methamphetamine on dopamine levels and dopamine release in rat striatum.

  1992cited by this paper
• Non-vesicular release of glutamate from glial cells by reversed electrogenic glutamate uptake

  1990cited by this paper
• Competitive and noncompetitive antagonists at N-methyl-D-aspartate receptors protect against methamphetamine-induced dopaminergic damage in mice.

  1990cited by this paper
• Calpain I activation is specifically related to excitatory amino acid induction of hippocampal damage

  1989influential reference
• Proteolytic processing of human brain alpha spectrin (fodrin): identification of a hypersensitive site

  1988cited by this paper
• Neurotoxicity in Dopamine and 5‐Hydroxytryptamine Terminal Fields: A Regional Analysis in Nigrostriatal and Mesolimbic Projections

  1988cited by this paper
• Electrogenic glutamate uptake in glial cells is activated by intracellular potassium

  1988cited by this paper
• Glutamate neurotoxicity and diseases of the nervous system.

  1988cited by this paper
• An improved and rapid HPLC-EC method for the isocratic separation of amino acid neurotransmitters from brain tissue and microdialysis perfusates.

  1988cited by this paper
• The role of astrocytes in hepatic encephalopathy.

  1987cited by this paper
• Dopamine nerve terminal degeneration produced by high doses of methylamphetamine in the rat brain.

  1982cited by this paper
• Long-term effects of repeated methylamphetamine administration on dopamine and serotonin neurons in the rat brain: a regional study.

  1980cited by this paper
• Long-lasting depletions of striatal dopamine and loss of dopamine uptake sites following repeated administration of methamphetamine.

  1980cited by this paper
• METABOLISM OF AMINO ACIDS AND AMMONIA IN RAT BRAIN CORTEX SLICES IN VITRO: A POSSIBLE ROLE OF AMMONIA IN BRAIN FUNCTION

  1975cited by this paper
• The acute action of ammonia on rat brain metabolism in vivo.

  1973cited by this paper

• Novel neurotherapeutic targets for substance use disorders: Neuroplasticity, neuroinflammation, gasotransmitters and non-canonical organ systems

  2025cites this paper
• Treadmill Exercise Training Ameliorates Apoptotic Cells and DNA Oxidation in the Cerebral Cortex of Rats Exposed to Chronic Ketamine Abuse

  2025cites this paper
• Methamphetamine-induced impairment of memory and fleeting neuroinflammation: profiling mRNA changes in mouse hippocampus following short-term and long-term exposure.

  2024cites this paper
• NHH promotes Sepsis-associated Encephalopathy with the expression of AQP4 in astrocytes through the gut-brain Axis

  2024cites this paper
• Effect of Neurofeedback Training Along With Swimming Exercise on the Stress, Anxiety, Depression, Severity of Dependence, and Craving in Methamphetamine-Dependent Patients

  2024cites this paper
• Methamphetamine Neurotoxicity: Neurotoxic Effects, Mechanism of Toxicity, Molecular Mechanisms and Treatment Strategies.

  2024cites this paper
• The Role of Sgt1 in Methamphetamine/Hyperthermia-induced Necroptosis.

  2024cites this paper
• Effects of chronic methamphetamine exposure on rewarding behavior and neurodegeneration markers in adult mice

  2023cites this paper
• Amphetamines abuse and depression: Focus on TRPC channels.

  2023cites this paper
• The Role of Hyperthermia in Methamphetamine-Induced Depression-Like Behaviors: Protective Effects of Coral Calcium Hydride

  2022cites this paper
• Methamphetamine-induced lethal toxicity in zebrafish larvae

  2022cites this paper
• Molecular mechanisms of programmed cell death in methamphetamine-induced neuronal damage

  2022cites this paper
• HISTOPATHOLOGICAL EVIDENCE THAT DIETHYLENE GLYCOL PRODUCES KIDNEY AND NERVOUS SYSTEM DAMAGE IN RATS.

  2022cites this paper
• A review of basic to clinical studies of the association between hyperammonemia, methamphetamine

  2022cites this paper
• Natural Products in Modulating Methamphetamine-Induced Neuronal Apoptosis

  2022cites this paper
• Methamphetamine-Associated Hyperammonemic Encephalopathy: Case Reports.

  2021cites this paper
• Untargeted metabolomics analysis by gas chromatography/time‐of‐flight mass spectrometry of human serum from methamphetamine abusers

  2021cites this paper
• Combined and sequential effects of alcohol and methamphetamine in animal models.

  2021cites this paper
• Effect of Chaihu-jia-Longgu-Muli decoction on withdrawal symptoms in rats with methamphetamine-induced conditioned place preference

  2021cites this paper
• Electro-acupuncture Alleviates METH Withdrawal-induced Spatial Memory Deficits by Restoring Astrocyte-drived Glutamate Uptake in dCA1

  2020cites this paper
• Abuse potential and toxicity of the synthetic cathinones (i.e., "Bath salts").

  2020cites this paper
• Differential effects of synthetic psychoactive cathinones and amphetamine stimulants on the gut microbiome in mice

  2020cites this paper
• Synthetic psychoactive cathinones: Hypothermia and reduced lethality compared to methamphetamine and methylenedioxymethamphetamine.

  2020cites this paper
• High ambient temperature increases the toxicity and lethality of 3,4-methylenedioxymethamphetamine and methcathinone.

  2020cites this paper
• MeBib Suppressed Methamphetamine Self-Administration Response via Inhibition of BDNF/ERK/CREB Signal Pathway in the Hippocampus

  2020cites this paper
• Increasing excitation versus decreasing inhibition in auditory cortex: consequences on the discrimination performance between communication sounds

  2020cites this paper
• Role of alpha-synuclein phosphorylation at Serine 129 in methamphetamine-induced neurotoxicity in vitro and in vivo

  2020cites this paper
• Instant activation of TRP channels by NH4+ promotes neuronal bursting and glutamate spikes in CA1 neurons

  2020cites this paper
• Glutamate homeostasis and dopamine signaling: implications for psychostimulant addiction behavior.

  2020cites this paper
• Activation of Trace Amine-Associated Receptor 1 Stimulates an Antiapoptotic Signal Cascade via Extracellular Signal-Regulated Kinase 1/2

  2019cites this paper
• Inflammatory mechanisms of abused drugs

  2019cites this paper
• Ammonia induces calpain-dependent cleavage of CRMP-2 during neurite degeneration in primary cultured neurons

  2019cites this paper
• Postmortem Study of Molecular and Histological Changes in the CA1 Hippocampal Region of Chronic Methamphetamine User

  2019cites this paper
• Serial exposure to ethanol drinking and methamphetamine enhances glutamate excitotoxicity

  2019cites this paper
• Lactulose attenuates METH-induced neurotoxicity by alleviating the impaired autophagy, stabilizing the perturbed antioxidant system and suppressing apoptosis in rat striatum.

  2018cites this paper
• Neurotoxic Agent-Induced Injury in Neurodegenerative Disease Model: Focus on Involvement of Glutamate Receptors

  2018cites this paper
• Dissociation between hypothermia and neurotoxicity caused by mephedrone and methcathinone in TPH2 knockout mice

  2018cites this paper
• Effects of sequential ethanol exposure and repeated high-dose methamphetamine on striatal and hippocampal dopamine, serotonin and glutamate tissue content in Wistar rats.

  2018influential citation
• Effects of Administered Ethanol and Methamphetamine on Glial Glutamate Transporters in Rat Striatum and Hippocampus

  2017cites this paper
• Assessing the role of dopamine in the differential neurotoxicity patterns of methamphetamine, mephedrone, methcathinone and 4-methylmethamphetamine.

  2017cites this paper
• Swimming exercise attenuates psychological dependence and voluntary methamphetamine consumption in methamphetamine withdrawn rats

  2016cites this paper
• Cholecystokinin-8 inhibits methamphetamine-induced neurotoxicity via an anti-oxidative stress pathway.

  2016cites this paper
• Peripheral ammonia and blood brain barrier structure and function after methamphetamine.

  2016cites this paper
• Effects of Ceftriaxone on Glial Glutamate Transporters in Wistar Rats Administered Sequential Ethanol and Methamphetamine

  2016cites this paper
• Peripheral Influences of Methamphetamine Neurotoxicity

  2016cites this paper
• Methamphetamine-mediated endoplasmic reticulum (ER) stress induces type-1 programmed cell death in astrocytes via ATF6, IRE1α and PERK pathways

  2016cites this paper
• Ceftriaxone attenuates ethanol drinking and restores extracellular glutamate concentration through normalization of GLT-1 in nucleus accumbens of male alcohol-preferring rats.

  2015cites this paper
• Effect of the environmental enrichment on the severity of psychological dependence and voluntary methamphetamine consumption in methamphetamine withdrawn rats.

  2015cites this paper
• Methamphetamine effects on blood-brain barrier structure and function

  2015cites this paper
• Methamphetamine-induced toxicity: an updated review on issues related to hyperthermia.

  2014cites this paper
• Methamphetamine Neurotoxicity and Neuroinflammatory Processes

  2014cites this paper
• Iranian Journal of Basic Medical Sciences Swimming Exercise Attenuates Psychological Dependence and Voluntary Methamphetamine Consumption in Methamphet- Amine Withdrawn Rats

  year unknowncites this paper