Reduced tubulin polyglutamylation suppresses flagellar shortness in Chlamydomonas

T. Kubo,M. Hirono,Takumi Aikawa,R. Kamiya,G. Witman

Published 2015 in Molecular Biology of the Cell

ABSTRACT

Tubulin polyglutamylation is a posttranslational modification known to affect ciliary/flagellar motility and assembly. Investigation of Chlamydomonas mutants deficient in axonemal polyglutamylation shows that polyglutamylation functions by increasing tubulin turnover at the flagellar tip and reducing axonemal stability.

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