The elongation of primary cilia via the acetylation of α-tubulin by the treatment with lithium chloride in human fibroblast KD cells

No abstract is available for this paper.

• Publication year

  2015

• Venue

  Medical Molecular Morphology

• Publication date

  2015-03-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1007/s00795-014-0076-xPMID 24760594
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Mice lacking α-tubulin acetyltransferase 1 are viable but display α-tubulin acetylation deficiency and dentate gyrus distortion.

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  2013cited by this paper
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  2013cited by this paper
• Targeting of CRMP-2 to the Primary Cilium Is Modulated by GSK-3β

  2012influential reference
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  2012cited by this paper
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  2010influential reference
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  2009cited by this paper
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  2009influential reference
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  2008cited by this paper
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  2008cited by this paper
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  2007cited by this paper
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  2007cited by this paper
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  2006cited by this paper
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  2004influential reference
• Cell biology of normal and abnormal ciliogenesis in the ciliated epithelium.

  2004cited by this paper
• Regulation of Flagellar Assembly by Glycogen Synthase Kinase 3 in Chlamydomonas reinhardtii

  2004cited by this paper
• Molecular targets of lithium action.

  2003influential reference
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  2002cited by this paper
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  2002cited by this paper
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  2002cited by this paper
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  1999cited by this paper
• Regulation of flagellar length in Chlamydomonas.

  1998cited by this paper
• Ultrastructural observation on ‘transitional tubules’ in human oviductal ciliogenic cells

  1997cited by this paper
• Microtubules containing acetylated alpha-tubulin in mammalian cells in culture

  1987cited by this paper
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  1986cited by this paper
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  1985cited by this paper
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  1983cited by this paper
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  1971cited by this paper
• Cilia in cell-cultured fibroblasts. 3. Relationship between mitotic activity and cilium frequency in mouse 3T6 fibroblasts.

  1971cited by this paper

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  2024cites this paper
• GDF15 controls primary cilia morphology and function thereby affecting progenitor proliferation

  2024cites this paper
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  2023cites this paper
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