Hereditary nephrotic syndrome: a systematic approach for genetic testing and a review of associated podocyte gene mutations

Several genes have been implicated in genetic forms of nephrotic syndrome occurring in children. It is now known that the phenotypes associated with mutations in these genes display significant variability, rendering genetic testing and counselling a more complex task. This review will focus on the recent clinical findings associated with those genes known to be involved in isolated steroid-resistant nephrotic syndrome in children and, thereby, propose an approach for appropriate mutational screening. The recurrence of proteinuria after transplantation in patients with hereditary forms of nephrotic syndrome will also be discussed.

• Publication year

  2010

• Venue

  Pediatric nephrology (Berlin, West)

• Publication date

  2010-03-24

• Fields of study

  Medicine

• Identifiers
  DOI 10.1007/s00467-010-1495-0PMID 20333530PMCID 2908444
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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