Contribution of oxidative stress to endothelial dysfunction in hypertension

Endothelial dysfunction is the hallmark of hypertension, which is a multifactorial disorder. In the cardiovascular system reactive oxygen species play a pivotal role in controlling the endothelial function and vascular tone. Physiologically, the endothelium-derived relaxing factors (EDRFs) and endothelium-derived contractile factors (EDCFs) that have functions on the vascular smooth muscle cells. The relaxation induced by the EDRFs nitric oxide (NO), prostacyclin, and the endothelium-derived hyperpolarization factor (EDHF) could be impaired in hypertension. The impaired ability of endothelial cells to release NO along with enhanced EDCFs production has been described to contribute to the endothelium dysfunction, which appears to lead to several cardiovascular diseases. The present review discusses the role of oxidative stress, vascular endothelium, and vascular tone control by EDRFs, mainly NO, and EDCFs in different models of experimental hypertension.

• Publication year

  2012

• Venue

  Front. Physio.

• Publication date

  2012-12-05

• Fields of study

  Medicine, Environmental Science

• Identifiers
  DOI 10.3389/fphys.2012.00441PMID 23227009PMCID 3514688
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Oxidative species increase arginase activity in endothelial cells through the RhoA/Rho kinase pathway

  2012cited by this paper
• What is comparable in comparative cognition?

  2012cited by this paper
• Mysteries of the brain. Why are our brains so big?

  2012cited by this paper
• Key Factors for the Emergence of Collective Decision in Invertebrates

  2012cited by this paper
• What's social about social learning?

  2012cited by this paper
• Orbital prefrontal cortex volume predicts social network size: an imaging study of individual differences in humans

  2012cited by this paper
• Corvid Re-Caching without ‘Theory of Mind’: A Model

  2012cited by this paper
• Radar Tracking and Motion-Sensitive Cameras on Flowers Reveal the Development of Pollinator Multi-Destination Routes over Large Spatial Scales

  2012cited by this paper
• Recognition of Social Identity in Ants

  2012cited by this paper
• Three-dimensional reconstruction of brain-wide wiring networks in Drosophila at single-cell resolution.

  2011cited by this paper
• Friends and Foes from an Ant Brain's Point of View – Neuronal Correlates of Colony Odors in a Social Insect

  2011cited by this paper
• Social Network Size Affects Neural Circuits in Macaques

  2011cited by this paper
• Endothelium-Dependent Contractions in Hypertension: When Prostacyclin Becomes Ugly

  2011cited by this paper
• Single atom substitution in mouse protein kinase G eliminates oxidant sensing to cause hypertension

  2011cited by this paper
• Comparative analysis of constraints and caste differences in brain investment among social paper wasps

  2011cited by this paper
• Ruthenium-nitrite complex as pro-drug releases NO in a tissue and enzyme-dependent way.

  2011cited by this paper
• Specialized Face Learning Is Associated with Individual Recognition in Paper Wasps

  2011cited by this paper
• Parasitoidism, not sociality, is associated with the evolution of elaborate mushroom bodies in the brains of hymenopteran insects

  2011cited by this paper
• Gregarious desert locusts have substantially larger brains with altered proportions compared with the solitarious phase

  2010cited by this paper
• Rapid Decision-Making with Side-Specific Perceptual Discrimination in Ants

  2010cited by this paper
• Hydrogen peroxide as an endothelium-derived hyperpolarizing factor

  2010cited by this paper
• Socially induced brain development in a facultatively eusocial sweat bee Megalopta genalis (Halictidae)

  2010cited by this paper
• Chronic antioxidant treatment improves arterial renovascular hypertension and oxidative stress markers in the kidney in Wistar rats.

  2010cited by this paper
• Neural activity in the central complex of the insect brain is linked to locomotor changes.

  2010cited by this paper
• Neural reuse: A fundamental organizational principle of the brain

  2010cited by this paper
• Chronic Inhibition of Nitric-Oxide Synthase Potentiates Endothelium-Dependent Contractions in the Rat Aorta by Augmenting the Expression of Cyclooxygenase-2

  2010cited by this paper
• Ants recognize foes and not friends

  2009cited by this paper
• Are bigger brains better?

  2009cited by this paper
• Brain-size evolution and sociality in Carnivora

  2009cited by this paper
• Endothelium‐dependent contractions in SHR: a tale of prostanoid TP and IP receptors

  2009cited by this paper
• Endothelium negatively modulates the vascular relaxation induced by nitric oxide donor, due to uncoupling NO synthase.

  2009cited by this paper
• Prostanoids and reactive oxygen species: team players in endothelium-dependent contractions.

  2009cited by this paper
• Brain organization mirrors caste differences, colony founding and nest architecture in paper wasps (Hymenoptera: Vespidae)

  2009cited by this paper
• Antioxidant treatment with tempol and apocynin prevents endothelial dysfunction and development of renovascular hypertension.

  2009cited by this paper
• Collective cognition in animal groups.

  2009cited by this paper
• The chemical biology of nitric oxide: implications in cellular signaling.

  2008cited by this paper
• Diabetes-induced Coronary Vascular Dysfunction Involves Increased Arginase Activity

  2008cited by this paper
• Nitric Oxide, Tetrahydrobiopterin, Oxidative Stress, and Endothelial Dysfunction in Hypertension

  2008cited by this paper
• Age, sex, and dominance‐related mushroom body plasticity in the paperwasp Mischocyttarus mastigophorus

  2008cited by this paper
• Bidirectional Actions of Hydrogen Peroxide on Endothelial Nitric-oxide Synthase Phosphorylation and Function

  2008cited by this paper
• Vitamin C improves the effect of a new nitric oxide donor on the vascular smooth muscle from renal hypertensive rats.

  2008cited by this paper
• A novel mechanism of vascular relaxation induced by sodium nitroprusside in the isolated rat aorta.

  2008cited by this paper
• NAD(P)H oxidase-derived peroxide mediates elevated basal and impaired flow-induced NO production in SHR mesenteric arteries in vivo.

  2008cited by this paper
• Robust long-term social memories in a paper wasp.

  2008cited by this paper
• Correlation between Facial Pattern Recognition and Brain Composition in Paper Wasps

  2007cited by this paper
• Central Projections of Sensory Systems Involved in Honey Bee Dance Language Communication

  2007cited by this paper
• A critique of comparative studies of brain size

  2007cited by this paper
• Mushroom Body Volume Is Related to Social Aggression and Ovary Development in the Paperwasp Polistes instabilis

  2007cited by this paper
• EVIDENCE FOR COEVOLUTION OF SOCIALITY AND RELATIVE BRAIN SIZE IN THREE ORDERS OF MAMMALS

  2007cited by this paper
• Regulation of endothelial and myocardial NO synthesis by multi-site eNOS phosphorylation.

  2007cited by this paper
• Calcium and reactive oxygen species increase in endothelial cells in response to releasers of endothelium‐derived contracting factor

  2007cited by this paper
• Microcirculation and oxidative stress

  2007cited by this paper
• Do honeybees detect colour targets using serial or parallel visual search?

  2006cited by this paper
• Tetrahydrobiopterin, but Not l-Arginine, Decreases NO Synthase Uncoupling in Cells Expressing High Levels of Endothelial NO Synthase

  2006cited by this paper
• Endothelin-1-induced oxidative stress in DOCA-salt hypertension involves NADPH-oxidase-independent mechanisms.

  2006cited by this paper
• Age-dependent and task-related volume changes in the mushroom bodies of visually guided desert ants, Cataglyphis bicolor.

  2006cited by this paper
• DECREASED VASODILATION INDUCED BY A NEW NITRIC OXIDE DONOR IN TWO KIDNEY, ONE CLIP HYPERTENSIVE RATS IS DUE TO IMPAIRED K+ CHANNEL ACTIVATION

  2005cited by this paper
• Cellular and molecular biology of prostacyclin synthase.

  2005cited by this paper
• Reactive Oxygen Species Induce Tyrosine Phosphorylation of and Src Kinase Recruitment to NO-sensitive Guanylyl Cyclase*

  2005cited by this paper
• Individual recognition in ant queens.

  2005cited by this paper
• Ant Nestmate and Non-Nestmate Discrimination by a Chemosensory Sensillum

  2005cited by this paper
• Coevolution of generalist feeding ecologies and gyrencephalic mushroom bodies in insects.

  2005cited by this paper
• NAD(P)H oxidase and uncoupled nitric oxide synthase are major sources of glomerular superoxide in rats with experimental diabetic nephropathy.

  2005cited by this paper
• Redox modulation of vascular tone: focus of potassium channel mechanisms of dilation.

  2005cited by this paper
• Reactive oxygen species induce tyrosine phosphorylation of and Src kinase recruitment to NO-sensitive guanylyl cyclase

  2005cited by this paper
• Characterization of four different effects elicited by H2O2 in rat aorta.

  2005cited by this paper
• Roles of oxidative stress and antioxidant therapy in chronic kidney disease and hypertension

  2004cited by this paper
• Upregulation of Vascular Arginase in Hypertension Decreases Nitric Oxide–Mediated Dilation of Coronary Arterioles

  2004cited by this paper
• A macrocyclic nitrosyl ruthenium complex is a NO donor that induces rat aorta relaxation.

  2004cited by this paper
• Ca2+-Activated K+ Channels Underlying the Impaired Acetylcholine-Induced Vasodilation in 2K-1C Hypertensive Rats

  2004cited by this paper
• Arginine and endothelial and vascular health.

  2004cited by this paper
• Endothelial dysfunction.

  2004cited by this paper
• Mushroom body structural change is associated with division of labor in eusocial wasp workers (Polybia aequatorialis, Hymenoptera: Vespidae).

  2004cited by this paper
• From The Cover: Binocularity and brain evolution in primates.

  2004cited by this paper
• Mechanisms of endothelial dysfunction: clinical significance and preventive non-pharmacological therapeutic strategies.

  2003influential reference
• Phosphorylation of Threonine 497 in Endothelial Nitric-oxide Synthase Coordinates the Coupling of l-Arginine Metabolism to Efficient Nitric Oxide Production*

  2003cited by this paper
• Akt-dependent phosphorylation of serine 1179 and mitogen-activated protein kinase kinase/extracellular signal-regulated kinase 1/2 cooperatively mediate activation of the endothelial nitric-oxide synthase by hydrogen peroxide.

  2003cited by this paper
• Endothelial dysfunction.

  2003cited by this paper
• Visual signals of individual identity in the wasp Polistes fuscatus

  2002cited by this paper
• L-Arginine in cardiovascular disease: dream or reality?

  2002cited by this paper
• Oxidation of the zinc-thiolate complex and uncoupling of endothelial nitric oxide synthase by peroxynitrite.

  2002cited by this paper
• Expression of a Functionally Active gp91phox-Containing Neutrophil-Type NAD(P)H Oxidase in Smooth Muscle Cells From Human Resistance Arteries: Regulation by Angiotensin II

  2002cited by this paper
• Modulation by Peroxynitrite of Akt- and AMP-activated Kinase-dependent Ser1179 Phosphorylation of Endothelial Nitric Oxide Synthase*

  2002cited by this paper
• The concepts of ‘sameness’ and ‘difference’ in an insect

  2001cited by this paper
• NADH/NADPH Oxidase and Enhanced Superoxide Production in the Mineralocorticoid Hypertensive Rat

  2001cited by this paper
• Comparison of Brain Volumes between Single and Multiple Foundresses in the Paper Wasp Polistes dominulus

  2001cited by this paper
• Regulation of endothelium-derived nitric oxide production by the protein kinase Akt

  1999cited by this paper
• Increased NAD(P)H oxidase-mediated superoxide production in renovascular hypertension: evidence for an involvement of protein kinase C.

  1999cited by this paper
• Experience-expectant plasticity in the mushroom bodies of the honeybee.

  1998cited by this paper
• Evolution, discovery, and interpretations of arthropod mushroom bodies.

  1998cited by this paper
• Effect of xanthine oxidase inhibition on endothelium-dependent and nitrergic relaxations.

  1998cited by this paper
• Cyclooxygenase inhibition restores nitric oxide activity in essential hypertension.

  1997cited by this paper
• Oxidative stress in the Dahl hypertensive rat.

  1997cited by this paper
• Endothelial dysfunction coincides with an enhanced nitric oxide synthase expression and superoxide anion production.

  1997cited by this paper
• Role of superoxide in angiotensin II-induced but not catecholamine-induced hypertension.

  1997cited by this paper
• Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor tone.

  1996cited by this paper
• In vivo evidence for microvascular oxidative stress in spontaneously hypertensive rats. Hydroethidine microfluorography.

  1995cited by this paper
• Selective neuroanatomical plasticity and division of labour in the honeybee

  1993cited by this paper
• Endothelin stimulated by angiotensin II augments contractility of spontaneously hypertensive rat resistance arteries.

  1992cited by this paper
• Xanthine oxidase activity in rat pulmonary artery endothelial cells and its alteration by activated neutrophils.

  1989cited by this paper

• Association of placental manganese levels, maternal gut microbiota, and preeclampsia: a tripartite perspective

  2025cites this paper
• Endothelial Dysfunction: From Pathophysiology to Novel Therapeutic Approaches 2.0

  2025cites this paper
• Targeting endothelial oxidative stress in hypertension

  2025cites this paper
• The complement - dendritic cell - endothelial cell crosstalk in vascular inflammation.

  2025cites this paper
• Polyphenol-Microbiota Interactions in Atherosclerosis: The Role of Hydroxytyrosol and Tyrosol in Modulating Inflammation and Oxidative Stress

  2025cites this paper
• Mercury-Mediated Cardiovascular Toxicity: Mechanisms and Remedies

  2025cites this paper
• Knowledge domains and hotspots of the association between hypertension and noise: a bibliometric analysis and visualization study from 2003 to 2023

  2025cites this paper
• Differential Plasma Carotenoid Profiles in Hypertensive Disorders of Pregnancy

  2025cites this paper
• The relationship between mid-upper arm circumference and blood pressure in Walter Sisulu University community

  2024cites this paper
• Neurogranin expression regulates mitochondrial function and redox balance in endothelial cells

  2024cites this paper
• Effect of blueberry intervention on endothelial function: a systematic review and meta-analysis

  2024cites this paper
• The Pathophysiological, Genetic, and Hormonal Changes in Preeclampsia: A Systematic Review of the Molecular Mechanisms

  2024cites this paper
• Rice bran: Nutritional, phytochemical, and pharmacological profile and its contribution to human health promotion

  2023cites this paper
• İdiyopatik pulmoner fibrozisli hastalarda nabız dalga hızı, intima media kalınlığı ve akım aracılı dilatasyon ile kardiyovasküler risk değerlendirmesi

  2023cites this paper
• Chronic administration of catalase inhibitor attenuates hypertension in renovascular hypertensive rats.

  2023cites this paper
• Sympathetic and angiotensinergic activity in spontaneously hypertensive rats treated with 3-amino-1,2,4-triazole.

  2023cites this paper
• Effects of Hydroxytyrosol in Endothelial Functioning: A Comprehensive Review

  2023cites this paper
• Preeclampsia: Recent Advances in Predicting, Preventing, and Managing the Maternal and Fetal Life-Threatening Condition

  2023cites this paper
• Cardiovascular risk assessment with pulse wave velocity, intima media thickness, and flow-mediated dilatation in patients with idiopathic pulmonary fibrosis

  2023cites this paper
• Curcumin Attenuates Oxidative Stress-Induced Effects on TGF-β Expression and NF-κB Signaling in Bovine Aortic Endothelial Cells

  2023cites this paper
• Qiqilian ameliorates vascular endothelial dysfunction by inhibiting NLRP3-ASC inflammasome activation in vivo and in vitro

  2023cites this paper
• Association of gamma-tocopherol serum concentrations and blood pressure among adults in the United States: a cross-sectional study

  2023cites this paper
• Phytochemical composition and bioactivities of Crataegus aronia as antioxidant, antibacterial and antioxidative stress in red blood cells – Is it a window of hope for children with glucose-6-phosphate dehydrogenase deficiency

  2022cites this paper
• Perinatal plasma carotenoid and vitamin E concentrations with maternal blood pressure during and after pregnancy.

  2022cites this paper
• OXIDATIVE STRESS AND REPRODUCTIVE FUNCTION Oxidative stress in polycystic ovary syndrome

  2022cites this paper
• Pharmacological effects of statins in adult patients with type 2 diabetes mellitus: A protocol for systematic review and meta-analysis

  2022cites this paper
• Metabolomics analysis delineates the therapeutic effects of hydroethanolic extract of Cucumis sativus L. seeds on hypertension and isoproterenol-induced myocardial infarction.

  2022cites this paper
• Lung function impairment in relation to cognition and vascular brain lesions: the Rotterdam Study

  2022cites this paper
• Oxidative Stress-Induced Endothelial Dysfunction in Cardiovascular Diseases.

  2022cites this paper
• Reactive Oxygen Species Scavenging Nanomedicine for the Treatment of Ischemic Heart Disease

  2022cites this paper
• Therapeutic anti‐amyloid β antibodies cause neuronal disturbances

  2022cites this paper
• Oxidative stress in polycystic ovary syndrome (PCOS).

  2022cites this paper
• Ubiquinol ameliorates endothelial dysfunction and increases expression of miRNA-34a in a rat model of pulmonary hypertension

  2021cites this paper
• The wHole Story About Fenestrations in LSEC

  2021cites this paper
• Local delivery of a senolytic drug in ischemia and reperfusion-injured heart attenuates cardiac remodeling and restores impaired cardiac function.

  2021cites this paper
• Dynamics of skin microvascular blood flow in 4-6-year-old children in association with pre- and postnatal black carbon and particulate air pollution exposure.

  2021cites this paper
• Sex Differences in the Vasodilation Mediated by G Protein-Coupled Estrogen Receptor (GPER) in Hypertensive Rats

  2021cites this paper
• The Role of Mitochondrial Dysfunction in Preeclampsia: Causative Factor or Collateral Damage?

  2021cites this paper
• Endothelial Dysfunction in Atherosclerotic Cardiovascular Diseases and Beyond: From Mechanism to Pharmacotherapies

  2021cites this paper
• Phenotypic characterization of circulating endothelial cells induced by inflammation and oxidative stress in ankylosing spondylitis

  2021cites this paper
• Biological Functions and Activities of Rice Bran as a Functional Ingredient: A Review

  2021cites this paper
• Emerging role of long non-coding RNAs in endothelial dysfunction and their molecular mechanisms.

  2021cites this paper
• Cardio-protective effects of a dioxidovanadium(V) complex in male sprague–dawley rats with streptozotocin-induced diabetes

  2020cites this paper
• Protective Effect of Astragaloside IV on High Glucose-Induced Endothelial Dysfunction via Inhibition of P2X7R Dependent P38 MAPK Signaling Pathway

  2020cites this paper
• Endothelial dysfunction in neuroprogressive disorders—causes and suggested treatments

  2020influential citation
• Nicotinamide nucleotide transhydrogenase (NNT) regulates mitochondrial ROS and endothelial dysfunction in response to angiotensin II

  2020cites this paper
• Primary Dysmenorrhea in Relation to Oxidative Stress and Antioxidant Status: A Systematic Review of Case-Control Studies

  2020cites this paper
• Long-chain fatty dihydropyridines: Docking calcium channel studies and antihypertensive activity.

  2020cites this paper
• Quercetin improves vascular endothelial function through promotion of autophagy in hypertensive rats.

  2020cites this paper
• Nitric oxide donors as potential drugs for the treatment of vascular diseases due to endothelium dysfunction.

  2020cites this paper
• Combination of hyperglycaemia and hyperlipidaemia induces endothelial dysfunction: Role of the endothelin and nitric oxide systems

  2020cites this paper
• The angiotensin II type I receptor contributes to impaired cerebral blood flow autoregulation caused by placental ischemia in pregnant rats

  2019cites this paper
• The natural phenolic compounds as modulators of NADPH oxidases in hypertension.

  2019cites this paper
• NO donors induce vascular relaxation by different cellular mechanisms in hypertensive and normotensive rats.

  2019cites this paper
• The role of pericytes in brain disorders: from the periphery to the brain

  2019cites this paper
• Uric acid is a key player in salt-induced endothelial dysfunction: the therapeutic role of stigma maydis (corn silk) extract.

  2019cites this paper
• Mercury induces nuclear estrogen receptors to act as vasoconstrictors promoting endothelial denudation via the PI3K/Akt signaling pathway.

  2019cites this paper
• Catalase blockade reduces the pressor response to central cholinergic activation.

  2019cites this paper
• Cerebral venous congestion promotes blood-brain barrier disruption and neuroinflammation, impairing cognitive function in mice

  2019cites this paper
• Quercetin improves endothelial insulin sensitivity in obese mice by inhibiting Drp1 phosphorylation at serine 616 and mitochondrial fragmentation.

  2019cites this paper
• Nutritional and other health properties of olive pomace oil

  2019cites this paper
• TRAIL: A novel atheroprotective mechanism in the vasculature

  2019cites this paper
• Downregulation of circulating MOTS-c levels in patients with coronary endothelial dysfunction.

  2018cites this paper
• Periodic Assessment of Antenatal and Post Natal Serum Endothelin-1 (ET-1) and Nitric Oxide (NO) Levels in Hypertensive Disorders of Pregnancy (HDP)

  2018cites this paper
• From folk medicine to functional food: a review on the bioactive components and pharmacological properties of citrus peels

  2018cites this paper
• Diet-Induced Hyperinsulinemia as a Key Factor in the Etiology of Both Benign Prostatic Hyperplasia and Essential Hypertension?

  2018cites this paper
• Potentiation of endothelium-dependent vasorelaxation of mesenteric arteries from spontaneously hypertensive rats by gemigliptin, a dipeptidyl peptidase-4 inhibitor class of anti-diabetic drug

  2018cites this paper
• Systemic hypertension is not protective against chronic intraocular pressure elevation in a rodent model

  2018cites this paper
• Oxidative Stress Biomarkers as Prognostic Indicators of Severity in Patients With Dengue

  2018cites this paper
• Maoberry (Antidesma bunius) ameliorates oxidative stress and inflammation in cardiac tissues of rats fed a high-fat diet

  2018cites this paper
• Mathematical model of hypertension-induced arterial remodeling: A chemo-mechanical approach.

  2018cites this paper
• Elevated Circulating Trimethylamine N-Oxide Levels Contribute to Endothelial Dysfunction in Aged Rats through Vascular Inflammation and Oxidative Stress

  2017cites this paper
• Relaxation induced by the nitric oxide donor and cyclooxygenase inhibitor NCX2121 in renal hypertensive rat aortas

  2017cites this paper
• Development of an Adverse Outcome Pathway for the Onset of Hypertension by Oxidative Stress-Mediated Perturbation of Endothelial Nitric Oxide Bioavailability

  2017cites this paper
• Acute simvastatin treatment restores cerebral functional capillary density and attenuates angiotensin II‐induced microcirculatory changes in a model of primary hypertension

  2017cites this paper
• Antioxidant therapy for management of oxidative stress induced hypertension

  2017cites this paper
• Method Of Correction Of Endothelial Dysfunction Of Blood Vessels Of Patients With Peptic Ulcer Of Stomach And Duodenal Ulcers Combined With Arterial Hypertension And Diabetes Mellitus Type 2

  2017cites this paper
• The Study of Correlation between Diurnal Blood Pressure with Nocturnal Oxygen Desaturation and Nitrite Production in Subjects with Obstructive Sleep Apnea (OSA)

  2017cites this paper
• Cerebrovascular Disease: Consequences of Obesity-Induced Endothelial Dysfunction.

  2017cites this paper
• Inhibitors of soluble epoxide hydrolase minimize ischemia‐reperfusion‐induced cardiac damage in normal, hypertensive, and diabetic rats

  2017cites this paper
• Lymphocyte DNA damage and plasma antioxidant status in Korean subclinical hypertensive patients by glutathione S-transferase polymorphism

  2017cites this paper
• Retinal vessel morphology in rheumatoid arthritis: Association with systemic inflammation, subclinical atherosclerosis, and cardiovascular risk

  2017cites this paper
• Roselle supplementation prevents nicotine-induced vascular endothelial dysfunction and remodelling in rats.

  2017cites this paper
• Nicotinamide nucleotide transhydrogenase activity impacts mitochondrial redox balance and the development of hypertension in mice.

  2017cites this paper
• Antioxidant and phenolic characterization, bioavailability and protective effects under oxidative stress and endothelial dysfunction of a red wine pomace seasoning (RWPS)

  2016cites this paper
• Role of MicroRNA in Endothelial Dysfunction and Hypertension

  2016cites this paper
• Anti-hypertensive Herbs and their Mechanisms of Action: Part I

  2016cites this paper
• Auto-inhibitory regulation of angiotensin II functionality in hamster aorta during the early phases of dyslipidemia.

  2016cites this paper
• Effect of treatment with the antioxidant alpha-lipoic (thioctic) acid on heart and kidney microvasculature in spontaneously hypertensive rats

  2016influential citation
• Anti-hypertensive Herbs and their Mechanisms of Action: Part I

  2016cites this paper
• Association Between the Angiotensinogen Gene Polymorphism and The

  2016influential citation
• Fatores de risco associados ao agravamento de sepse em pacientes em Unidade de Terapia Intensiva

  2016cites this paper
• Assessing Mercury Risks for the Optimization of Nutrient Benefits from Wild-harvested Fish Consumption in the Northwest Territories, Canada

  2016cites this paper
• A single blueberry (Vaccinium corymbosum) portion does not affect markers of antioxidant defence and oxidative stress in healthy volunteers following cigarette smoking.

  2016cites this paper
• The endothelium as the common denominator in malignant hypertension and thrombotic microangiopathy.

  2016cites this paper
• Anti-Hypertensive Herbs and Their Mechanisms of Action: Part II

  2016cites this paper
• Association Between the Angiotensinogen Gene Polymorphism and The

  2016influential citation
• Oxidative stress and cardiovascular complications in polycystic ovarian syndrome.

  2015cites this paper
• N-nitro-l-arjinin metil ester (L-NAME) ile preeklampsi modeli oluşturulan sıçanlarda kurkuminin etkisinin incelenmesi

  2015cites this paper
• Oxidative Stress in Kawasaki Disease Vasculitis

  2015cites this paper