L-Arginine in cardiovascular disease: dream or reality?

No abstract is available for this paper.

• Publication year

  2002

• Venue

  Vascular Medicine

• Publication date

  2002-08-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1191/1358863x02vm434raPMID 12553744
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• Plasma concentration of asymmetric dimethylarginine, an endogenous inhibitor of nitric oxide synthase, is elevated in monkeys with hyperhomocyst(e)inemia or hypercholesterolemia.

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• Continuous perivascular L-arginine delivery increases total vessel area and reduces neointimal thickening after experimental balloon dilatation.

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• Asymmetric dimethylarginine plasma concentrations differ in patients with end-stage renal disease: relationship to treatment method and atherosclerotic disease.

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• Inhibition of nitric oxide synthesis in human epicardial coronary arteries and stenoses in relation to serum lipid level.

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• Effects of changing the availability of the substrate for nitric oxide synthase by L-arginine administration on coronary vasomotor tone in angina patients with angiographically narrowed and in patients with normal coronary arteries.

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• Review of alterations in endothelial nitric oxide production in diabetes: protective role of arginine on endothelial dysfunction.

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  1998cited by this paper
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  1998cited by this paper
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  1998cited by this paper
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  1998cited by this paper
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• Coronary stenosis dilatation induced by L-arginine.

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• Cigarette smoking is associated with increased human monocyte adhesion to endothelial cells: reversibility with oral L-arginine but not vitamin C.

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  1996cited by this paper
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  1996cited by this paper
• Dietary supplementation with L-arginine fails to restore endothelial function in forearm resistance arteries of patients with severe heart failure.

  1996cited by this paper
• Oral L-arginine improves endothelium-dependent dilation in hypercholesterolemic young adults.

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• Effect of L-arginine on in vitro plasmin-generation and fibrinogenolysis.

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• L-arginine decreases infarct size in rats exposed to environmental tobacco smoke.

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• Effects of L-arginine supplementation on endothelium-dependent coronary vasodilation in patients with angina pectoris and normal coronary arteriograms.

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• Increased adhesiveness of isolated monocytes to endothelium is prevented by vitamin C intake in smokers.

  1996cited by this paper
• Regression or progression. Dependency on vascular nitric oxide.

  1996cited by this paper
• Effects of dietary L-arginine on atherosclerosis and endothelium-dependent vasodilatation in the hypercholesterolemic rabbit. Response according to treatment duration, anatomic site, and sex.

  1996cited by this paper
• Arginine restores nitric oxide activity and inhibits monocyte accumulation after vascular injury in hypercholesterolemic rabbits.

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• Defective L-arginine-nitric oxide pathway in offspring of essential hypertensive patients.

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