Retinoic Acid Signaling Restricts the Cardiac Progenitor Pool

No abstract is available for this paper.

• Publication year

  2005

• Venue

  Science

• Publication date

  2005-01-14

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1126/SCIENCE.1101573PMID 15653502
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Organization of cardiac chamber progenitors in the zebrafish blastula

  2004cited by this paper
• Independent roles for retinoic acid in segmentation and neuronal differentiation in the zebrafish hindbrain.

  2004cited by this paper
• Beyond the neckless phenotype: influence of reduced retinoic acid signaling on motor neuron development in the zebrafish hindbrain.

  2004cited by this paper
• Erythropoietin and retinoic acid, secreted from the epicardium, are required for cardiac myocyte proliferation.

  2003cited by this paper
• A caudorostral wave of RALDH2 conveys anteroposterior information to the cardiac field

  2003cited by this paper
• Heart development: molecular insights into cardiac specification and early morphogenesis.

  2003cited by this paper
• Retinoic acid signalling in the zebrafish embryo is necessary during pre-segmentation stages to pattern the anterior-posterior axis of the CNS and to induce a pectoral fin bud.

  2002cited by this paper
• Retinoic acid signaling is required for a critical early step in zebrafish pancreatic development.

  2002cited by this paper
• Epicardial induction of fetal cardiomyocyte proliferation via a retinoic acid-inducible trophic factor.

  2002cited by this paper
• Embryonic retinoic acid synthesis is essential for heart morphogenesis in the mouse.

  2001cited by this paper
• The zebrafish neckless mutation reveals a requirement for raldh2 in mesodermal signals that pattern the hindbrain.

  2001cited by this paper
• BMS-189453, a novel retinoid receptor antagonist, is a potent testicular toxin.

  2001cited by this paper
• Serrate and Notch specify cell fates in the heart field by suppressing cardiomyogenesis.

  2000cited by this paper
• Retinoic acid is required in the mouse embryo for left-right asymmetry determination and heart morphogenesis.

  1999cited by this paper
• Notochord regulates cardiac lineage in zebrafish embryos.

  1998cited by this paper
• Retinoic acid can block differentiation of the myocardium after heart specification.

  1997cited by this paper
• Expression of the atrial-specific myosin heavy chain AMHC1 and the establishment of anteroposterior polarity in the developing chicken heart.

  1994cited by this paper
• Patterning the zebrafish heart tube: acquisition of anteroposterior polarity.

  1992cited by this paper

• Hedgehog and Bmp signaling pathways play opposing roles during establishment of the cardiac inflow tract in zebrafish

  2026cites this paper
• Hedgehog and Bmp signaling pathways play opposing roles during establishment of the cardiac inflow tract in zebrafish

  2025cites this paper
• Tbx1-dependent and independent pathways promote six gene expression downstream of retinoic acid signaling to determine cardiomyocyte number in zebrafish.

  2025cites this paper
• A retinoic acid:YAP1 signaling axis controls atrial lineage commitment

  2025cites this paper
• Early retinoic acid signaling organizes the body axis and defines domains for the forelimb and eye.

  2025cites this paper
• Chemical-induced heart defects using a transgenic zebrafish model

  2025cites this paper
• Retinoic acid production via the ray-finned fish gene beta-carotene oxygenase 1-like is essential for juvenile development

  2025cites this paper
• Retinoic acid promotes second heart field addition and regulates ventral aorta patterning in zebrafish.

  2025cites this paper
• Zebrafish as a Versatile Model for Cardiovascular Research: Peering into the Heart of the Matter

  2025cites this paper
• The molecular mechanisms of cardiac development and related diseases

  2024cites this paper
• Rewiring of the epigenome and chromatin architecture by exogenously induced retinoic acid signaling during zebrafish embryonic development

  2024cites this paper
• State-of-the-Art Differentiation Protocols for Patient-Derived Cardiac Pacemaker Cells

  2024cites this paper
• A Retinoic Acid:YAP1 signaling axis controls atrial lineage commitment

  2024cites this paper
• Screening (ant)agonistic activities of xenobiotics on the retinoic acid receptor alpha (RARα) using in vitro and in silico analysis.

  2024cites this paper
• Cxcr4a regulates heart progenitor development and cardiac rhythm in zebrafish

  2024influential citation
• Impaired retinoic acid signaling in cerebral cavernous malformations

  2023cites this paper
• The translation initiation factor homolog eif4e1c regulates cardiomyocyte metabolism and proliferation during heart regeneration

  2023influential citation
• Retinoic acid signaling pathway perturbation impacts mesodermal-tissue development in the zebrafish embryo: biomarker candidate identification using transcriptomics.

  2023cites this paper
• Identification of Greb1l as a genetic determinant of crisscross heart in mice showing torsion of the heart tube by shortage of progenitor cells.

  2023cites this paper
• Torsion of the heart tube by shortage of progenitor cells : identification of Greb1l as a genetic determinant of criss-cross hearts in mice

  2023cites this paper
• Human pluripotent stem cell-based models of heart development and disease.

  2023cites this paper
• Zebrafish as a Model to Study Retinoic Acid Signaling in Development and Disease

  2023cites this paper
• Transcriptome-based prediction of drugs, inhibiting cardiomyogenesis in human induced pluripotent stem cells

  2023cites this paper
• Lateral thinking in syndromic congenital cardiovascular disease

  2023cites this paper
• Dissecting mechanisms of chamber-specific cardiac differentiation and its perturbation following retinoic acid exposure.

  2022cites this paper
• The impact of Drew Noden's work on our understanding of craniofacial musculoskeletal integration

  2022cites this paper
• Endocardial identity is established during early somitogenesis by Bmp signalling acting upstream of npas4l and etv2

  2022cites this paper
• Retinoic acid, RARs and early development.

  2022cites this paper
• Retinoic acid signaling modulation guides in vitro specification of human heart field-specific progenitor pools

  2022cites this paper
• Modeling Human Cardiac Arrhythmias: Insights from Zebrafish

  2022cites this paper
• Patterning of vertebrate cardiac progenitor fields by retinoic acid signaling

  2021cites this paper
• Highlighting the gaps in hazard and risk assessment of unregulated Endocrine Active Substances in surface waters: retinoids as a European case study

  2021cites this paper
• Retinoic acid signaling restricts the size of the first heart field within the anterior lateral plate mesoderm.

  2021cites this paper
• GATA-targeted compounds modulate cardiac subtype cell differentiation in dual reporter stem cell line

  2021influential citation
• Atrial and Sinoatrial Node Development in the Zebrafish Heart

  2021cites this paper
• GATA-targeted compounds modulate cardiac subtype cell differentiation in dual reporter stem cell line

  2021influential citation
• A key moment for TiO2: Prenatal exposure to TiO2 nanoparticles may inhibit the development of offspring.

  2020cites this paper
• The Cdx transcription factors and retinoic acid play parallel roles in antero-posterior position of the pectoral fin field during gastrulation.

  2020cites this paper
• RA Signaling in Limb Development and Regeneration in Different Species.

  2020cites this paper
• The Biochemistry of Retinoid Signaling III: Vitamin A and Retinoic Acid in Embryonic Development

  2020cites this paper
• Vitamin A as a Transcriptional Regulator of Cardiovascular Disease

  2020cites this paper
• Retinoic acid promotes metabolic maturation of human Embryonic Stem Cell-derived Cardiomyocytes

  2020cites this paper
• Retinoic Acid Signaling and Heart Development.

  2020cites this paper
• Role of carotenoids and retinoids during heart development.

  2020cites this paper
• Pbx4 limits heart size and fosters arch artery formation by partitioning second heart field progenitors and restricting proliferation

  2020cites this paper
• Subtype‐specific cardiomyocytes for precision medicine: Where are we now?

  2020cites this paper
• Aldehyde dehydrogenases contribute to skeletal muscle homeostasis in healthy, aging, and Duchenne muscular dystrophy patients

  2020cites this paper
• Homozygous MESP1 knock-in reporter hESCs facilitated cardiovascular cell differentiation and myocardial infarction repair

  2020cites this paper
• Retinoic acid signaling pathways

  2019cites this paper
• How glyphosate and its associated acidity affect early development in zebrafish (Danio rerio)

  2019cites this paper
• A novel dual reporter embryonic stem cell line for toxicological assessment of teratogen-induced perturbation of anterior–posterior patterning of the heart

  2019cites this paper
• Endocardial differentiation in zebrafish occurs during early somitogenesis and is dependent on BMP and etv2 signalling

  2019cites this paper
• Discovery of retinoic acid receptor agonists as proliferators of cardiac progenitor cells through a phenotypic screening approach

  2019cites this paper
• Retinoic acid signaling in heart development

  2019cites this paper
• How glyphosate and its associated acidity affect early development in zebrafish ([i]Danio rerio[i])

  2019cites this paper
• Recent insights on the role and regulation of retinoic acid signaling during epicardial development

  2019cites this paper
• Nr2f-dependent allocation of ventricular cardiomyocyte and pharyngeal muscle progenitors

  2019cites this paper
• The ubiquitin ligase HECTD1 promotes retinoic acid signaling required for development of the aortic arch

  2019influential citation
• Hox genes: Downstream “effectors” of retinoic acid signaling in vertebrate embryogenesis

  2019cites this paper
• Reiterative Mechanisms of Retinoic Acid Signaling during Vertebrate Heart Development

  2019influential citation
• Novel Regulators of Feeding and Cardiovascular Physiology in Fish

  2018cites this paper
• The flow responsive transcription factor Klf2 is required for myocardial wall integrity by modulating Fgf signaling

  2018cites this paper
• Endothelial Contributions to Zebrafish Heart Regeneration

  2018cites this paper
• The developmental origin of heart size and shape differences in Astyanax mexicanus populations

  2018cites this paper
• Spatial Allocation and Specification of Cardiomyocytes during Zebrafish Embryogenesis

  2017cites this paper
• Perturbations in cell signaling elicit early cardiac defects in mucopolysaccharidosis type II

  2017cites this paper
• The transcription factor Foxc1a in zebrafish directly regulates expression of nkx2.5, encoding a transcriptional regulator of cardiac progenitor cells

  2017cites this paper
• Mechanisms of retinoic acid signaling during cardiogenesis.

  2017cites this paper
• Retinoic acid in developmental toxicology: Teratogen, morphogen and biomarker.

  2017cites this paper
• Characterizing the Contribution of First and Second Heart Field-derived Cells in Zebrafish Cardiac Development

  2017cites this paper
• Human Pluripotent Stem Cell Differentiation into Functional Epicardial Progenitor Cells

  2017cites this paper
• Fractionation of embryonic cardiac progenitor cells and evaluation of their differentiation potential.

  2017cites this paper
• PREPARING CARDOMYOCYTES FROM STEM CELLS AND USES THEREOF

  2017cites this paper
• Explorer Illuminating cardiac development : Advances in imaging add new dimensions to the utility of zebrafish genetics

  2017cites this paper
• Comparative Toxicogenomic Responses to the Flame Retardant mITP in Developing Zebrafish.

  2017cites this paper
• Congenital diaphragmatic hernia after exposure to a triple retinoic acid antagonist during pregnancy

  2017cites this paper
• The role of R-spondin3 in coronary artery formation and novel roles for retinoic acid signaling in cardiac development and repair

  2017cites this paper
• BMP and retinoic acid regulate anterior–posterior patterning of the non-axial mesoderm across the dorsal–ventral axis

  2016cites this paper
• Retinoic Acid Signaling Is Essential for Valvulogenesis by Affecting Endocardial Cushions Formation in Zebrafish Embryos

  2016cites this paper
• A Retinoic Acid-Hedgehog Cascade Coordinates Mesoderm-Inducing Signals and Endoderm Competence during Lung Specification.

  2016influential citation
• Strategies for analyzing cardiac phenotypes in the zebrafish embryo.

  2016cites this paper
• Evolution of the Amphibian Head and Neck: Fate and Patterning of Cranial Mesoderm in the Axolotl (Ambystoma Mexicanum)

  2016cites this paper
• Retinoic Acid Signaling and Heart Development

  2015cites this paper
• Excessive feedback of Cyp26a1 promotes cell non-autonomous loss of retinoic acid signaling.

  2015cites this paper
• ASYMMETRIC CELL CONVERGENCE-DRIVEN FIN BUD INITIATION AND PREPATTERN REQUIRES TBX5A CONTROL OF A MESENCHYMAL FGF SIGNAL

  2015cites this paper
• Dual embryonic origin and patterning of the pharyngeal skeleton in the axolotl (Ambystoma mexicanum)

  2015cites this paper
• Rdh10a Provides a Conserved Critical Step in the Synthesis of Retinoic Acid during Zebrafish Embryogenesis

  2015cites this paper
• Input overload: Contributions of retinoic acid signaling feedback mechanisms to heart development and teratogenesis

  2015influential citation
• Engineered Human Cardiac Tissue from Muscle Derived Stem Cells

  2015cites this paper
• Mechanisms of retinoic acid signalling and its roles in organ and limb development

  2015cites this paper
• Medicinal Chemistry Approaches to Heart Regeneration.

  2015cites this paper
• ZebRA: An overview of retinoic acid signaling during zebrafish development.

  2015cites this paper
• Signaling through retinoic acid receptors in cardiac development: Doing the right things at the right times.

  2015influential citation
• Pbx4 is Required to Restrict Second Heart Field and Ventricular Outflow Tract Size

  2015cites this paper
• Novel Video Imaging to Examine Cardiac Function in Xenopus Embryos

  2015cites this paper
• Zebrafish models of heart development and cardiovascular diseases

  2015cites this paper
• Atrial-like cardiomyocytes from human pluripotent stem cells are a robust preclinical model for assessing atrial-selective pharmacology

  2015influential citation
• Asymmetric cell convergence-driven zebrafish fin bud initiation and pre-pattern requires Tbx5a control of a mesenchymal Fgf signal

  2015cites this paper
• Heart Regeneration. The Developmental and Stem Cell Biology Approach.

  2014cites this paper
• Overexpression of miR-19b Impairs Cardiac Development in Zebrafish by Targeting ctnnb1

  2014cites this paper