Kidney Slices of Human and Rat to Characterize Cisplatin-Induced Injury on Cellular Pathways and Morphology

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Toxicologic pathology (Print)

• Publication date

  2004-08-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1080/01926230490508821PMID 15603542
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Identification of platform-independent gene expression markers of cisplatin nephrotoxicity.

  2004cited by this paper
• Kinetic study on the reaction of cisplatin with metallothionein.

  2003cited by this paper
• Metallothionein is a potential negative regulator of apoptosis.

  2003cited by this paper
• Kinetics of cisplatin binding to cellular DNA and modulations by thiol-blocking agents and thiol drugs.

  2002cited by this paper
• Cell metabolism in the regulation of programmed cell death.

  2002cited by this paper
• Cisplatin ototoxicity: involvement of iron and enhanced formation of superoxide anion radicals.

  2001cited by this paper
• Identification of genes that mediate sensitivity to cisplatin.

  2001cited by this paper
• Cisplatin Induces the Proapoptotic Conformation of Bak in a ΔMEKK1-Dependent Manner

  2001cited by this paper
• Modulation of cisplatin cytotoxicity and cisplatin-induced DNA cross-links in HepG2 cells by regulation of glutathione-related mechanisms.

  2001cited by this paper
• Assessment of cisplatin-induced nephrotoxicity by microarray technology.

  2001cited by this paper
• Is cisplatin-induced cell death always produced by apoptosis?

  2001influential reference
• Role of Gadd45 in apoptosis.

  2000cited by this paper
• A comparison of apoptosis and necrosis induced by hepatotoxins in HepG2 cells.

  2000cited by this paper
• [Platinum salts: cytotoxic mechanisms of action, mechanisms of resistance of cancer cells, interactions with ionizing radiation, specificity of carboplatin].

  2000cited by this paper
• Heme oxygenase-1 gene ablation or expression modulates cisplatin-induced renal tubular apoptosis.

  2000cited by this paper
• Renal toxicity caused by cisplatinum in glutathione-depleted metallothionein-null mice.

  2000cited by this paper
• Carrier-mediated uptake of cisplatin by the OK renal epithelial cell line.

  2000cited by this paper
• Multiple physiological functions for multidrug transporter P-glycoprotein?

  2000cited by this paper
• Evaluation préclinique de l'activité antitumorale des inhibiteurs de l'aromatase

  2000cited by this paper
• Protective role of metallothionein on DNA damage in rat kidney caused by cis-diamminedichloroplatinum.

  2000cited by this paper
• Potentiation of cisplatin-induced nephrotoxicity in rats by allopurinol.

  2000cited by this paper
• GADD45 induction of a G2/M cell cycle checkpoint.

  1999cited by this paper
• Modulation of cisplatinum cytotoxicity by p53: effect of p53-mediated apoptosis and DNA repair.

  1999cited by this paper
• Graded ATP depletion can cause necrosis or apoptosis of cultured mouse proximal tubular cells.

  1998cited by this paper
• Graded ATP depletion can cause necrosis or apoptosis of cultured mouse proximal tubular cells.

  1998cited by this paper
• Cisplatin- and paclitaxel-induced apoptosis of ovarian carcinoma cells and the relationship between bax and bak up-regulation and the functional status of p53.

  1998cited by this paper
• Cellular and molecular determinants of cisplatin resistance.

  1998cited by this paper
• Metallothionein (MT)-null mice are sensitive to cisplatin-induced hepatotoxicity.

  1998cited by this paper
• Temporal induction of clusterin in cisplatin nephrotoxicity.

  1997cited by this paper
• Suppression of P-glycoprotein expression and multidrug resistance by DNA cross-linking agents.

  1997cited by this paper
• Decomposition Kinetics of Cisplatin in Human Biological Fluids

  1996cited by this paper
• DNA damage inducible-gene expression following platinum treatment in human ovarian carcinoma cell lines

  1996cited by this paper
• Mechanisms of death induced by cisplatin in proximal tubular epithelial cells: apoptosis vs. necrosis.

  1996cited by this paper
• Cisplatin, camptothecin, and taxol sensitivities of cells with p53-associated multidrug resistance.

  1996cited by this paper
• Induction of heme oxygenase in toxic renal injury: a protective role in cisplatin nephrotoxicity in the rat.

  1995cited by this paper
• Critical subcellular targets of cisplatin and related platinum analogs in rat renal proximal tubule cells.

  1995cited by this paper
• Differential toxicity of cisplatin, carboplatin, and CI-973 correlates with cellular platinum levels in rat renal cortical slices.

  1995cited by this paper
• GS-X pump is functionally overexpressed in cis-diamminedichloroplatinum (II)-resistant human leukemia HL-60 cells and down-regulated by cell differentiation.

  1994cited by this paper
• Urinary pi-class glutathione transferase as an indicator of tubular damage in the human kidney.

  1994cited by this paper
• Toxicity of Cisplatin and Mercuric Chloride in Human Kidney Cortical Slices

  1994cited by this paper
• Immunohistochemical localization of alpha and pi class glutathione transferases in normal human tissues.

  1993cited by this paper
• Immunohistochemical Localization of α and φ Class Glutathione Transferases in Normal Human Tissues

  1993cited by this paper
• Effect of chronic cisplatin administration on phosphate and glucose transport by the renal brush border membrane.

  1991cited by this paper
• Augmentation of cisplatin (DDP) cytotoxicity in vivo by DL-buthionine sulfoximine (BSO) in DDP-sensitive and-resistant rat ovarian tumors and its relation to DNA interstrand cross links.

  1991cited by this paper
• Immunohistologic localization of alpha, Mu, and Pi class glutathione S‐transferases in human tissues

  1991cited by this paper
• Histopathological Study of Human Cisplatin Nephropathy

  1986cited by this paper
• Brush border membranes

  1983cited by this paper
• Cis-diamminedichlorplatinum-induced acute renal failure in the rat.

  1982cited by this paper
• Acute and chronic cisplatin nephropathy in rats.

  1981cited by this paper
• Acute and chronic cisplatin nephropathy in rats.

  1981cited by this paper
• Acute renal failure after cis-dichlorodiammineplatinum(II) and gentamicin-cephalothin therapies.

  1978cited by this paper
• Long term effect of Cis‐Diamminedichloride platinum (CDDP) on renal function and structure in man

  1978cited by this paper
• The renal pathology in clinical trials of Cis‐platinum (II) diamminedichloride

  1977cited by this paper
• Phase II study of cis-dichlorodiammineplatinum(II) (NSC-119875) in combination with cyclophosphamide (NSC-26271) in the treatment of human malignancies.

  1975cited by this paper
• Phase II study of cis-dichlorodiammineplatinum(II) (NSC-119875) in combination with cyclophosphamide (NSC-26271) in the treatment of human malignancies.

  1975cited by this paper
• Platinum nephrotoxicity

  1974cited by this paper
• Mechanisms of Death

  1966cited by this paper
• Radiation: Studies of Mouse Cells Lacking P53-mediated Dna Repair Responses to Uv

  year unknowncited by this paper

• Whole-organ and whole-body 3D atlases enable cellome-wide profiling.

  2026cites this paper
• The protective effect of curcumin nanoparticles on renal damage caused by a combination of bleomycin, etoposide, and cisplatin

  2025cites this paper
• Mouse precision-cut liver and kidney slices: an optimized ex vivo model for acute toxicity testing

  2025cites this paper
• Chemoprotective Mechanism of Sodium Thiosulfate Against Cisplatin-Induced Nephrotoxicity Is via Renal Hydrogen Sulfide, Arginine/cAMP and NO/cGMP Signaling Pathways

  2025cites this paper
• Mannitol versus furosemide for prevention of cisplatin-induced nephrotoxicity in a multicenter retrospective cohort study

  2025cites this paper
• Impact of Pre-treatment Proteinuria Progression on the Risk of Increased Proteinuria During Ramucirumab Therapy

  2025cites this paper
• Enzymes as indispensable markers in disease diagnosis.

  2024cites this paper
• An integrated view of cisplatin-induced nephrotoxicity, hepatotoxicity, and cardiotoxicity: characteristics, common molecular mechanisms, and current clinical management

  2024cites this paper
• Fanconi syndrome with acute proximal tubular injury induced by a dietary supplement containing beni-koji: a case series report

  2024cites this paper
• Association of Oral Tobacco-Free Nicotine Delivery Product with Acute Renal Tubular Necrosis

  2024cites this paper
• Visualization of intracellular ATP dynamics in the whole kidney under pathophysiological conditions using the kidney slice culture system

  2024cites this paper
• Role of Transcription Factor EB in Mitochondrial Dysfunction of Cisplatin-Induced Acute Kidney Injury

  2023cites this paper
• Valproic acid treatment attenuates cisplatin‐induced kidney injury by suppressing proximal tubular cell damage

  2023cites this paper
• Chapter 1: Evaluation of kidney function in patients undergoing anticancer drug therapy, from clinical practice guidelines for the management of kidney injury during anticancer drug therapy 2022

  2023cites this paper
• Acquired Disorders of Hypomagnesemia.

  2023cites this paper
• Protective effect of quercetin against corneal toxicities induced by cisplatin in male mice

  2022cites this paper
• Evaluation of Platinum Anticancer Drug-Induced Kidney Injury in Primary Culture of Rat Kidney Tissue Slices by Using Gas-Permeable Plates.

  2022cites this paper
• Analysis of Renal Platinum Content as a Novel Approach to Protect against Cisplatin Nephrotoxicity: A Review

  2021cites this paper
• Preventive effect of 20 mEq and 8 mEq magnesium supplementation on cisplatin-induced nephrotoxicity: a propensity score–matched analysis

  2021cites this paper
• An overview of diagnosis and management of drug‐induced hypomagnesemia

  2021cites this paper
• Abrogation of cisplatin-induced nephrotoxicity in rats and HEK-293 cell lines by formononetin: in vivo and in vitro study

  2021cites this paper
• Alternative in vitro models for safety and toxicity evaluation of nutraceuticals

  2021cites this paper
• Impact of Treatment with Imatinib on Renal Histology in Albino Rats

  2020cites this paper
• Protective effects of Citrus limonia oil against cisplatin-induced nephrotoxicity

  2020cites this paper
• Cisplatin-induced renal toxicity in elderly people

  2020cites this paper
• Curcumin nanoparticles ameliorate hepatotoxicity and nephrotoxicity induced by cisplatin in rats

  2020cites this paper
• Role of stem cells in decreasing renal failure in rats

  2020cites this paper
• Potential renoprotective effects of silymarin against vancomycin-induced nephrotoxicity in rats

  2020cites this paper
• Conventional chemotherapy

  2020cites this paper
• The Protective Effect of Omega3 Against Amikacin- Induced Nephrotoxicity in Rats

  2020cites this paper
• Quantitative prediction of human pharmacokinetic responses to drugs via fluidically coupled vascularized organ chips

  2020cites this paper
• High-intensity interval training is more effective than continuous training to reduce inflammation markers in female rats with cisplatin nephrotoxicity.

  2020cites this paper
• Sinapic acid attenuates cisplatin-induced nephrotoxicity through peroxisome proliferator-activated receptor gamma agonism in rats

  2020cites this paper
• Patient-derived tumour models for personalized therapeutics in urological cancers

  2020cites this paper
• Protective effects of sesamol against cisplatin-induced nephrotoxicity in rats: A mechanistic approach

  2020cites this paper
• Effect of Common Medications on the Expression of SARS‐CoV‐2 Entry Receptors in Kidney Tissue

  2020cites this paper
• Nanoparticulated Honokiol Mitigates Cisplatin-Induced Chronic Kidney Injury by Maintaining Mitochondria Antioxidant Capacity and Reducing Caspase 3-Associated Cellular Apoptosis

  2019cites this paper
• Testicular Cancer Survivorship.

  2019cites this paper
• The Screening of Renoprotective Agents by 99mTc-DMSA: A Review of Preclinical Studies.

  2019cites this paper
• Recapitulating human tissue damage, repair, and fibrosis with human pluripotent stem cell‐derived organoids

  2019cites this paper
• University of Birmingham A critical review of adverse effects to the kidney

  2019cites this paper
• The Role of Vitamin C on the Structural Changes of Male Albino Rats Kidney Induced by Tramadol

  2019cites this paper
• The Modern Use of Stem Cells in Treatment of Renal Failure in Rat Model

  2019cites this paper
• Kidney Safety Assessment: Current Practices in Drug Development.

  2019cites this paper
• Dietary restriction regimens for fighting kidney disease: Insights from rodent studies.

  2019cites this paper
• Ex vivo toxicological evaluation of experimental anticancer gold(i) complexes with lansoprazole-type ligands.

  2019cites this paper
• Effect of Suramin on Renal Proximal Tubular Cells Damage Induced by Cisplatin in Rats (Histological and Immunohistochemical Study)

  2019cites this paper
• NAG-targeting fluorescence based probe for precision diagnosis of kidney injury.

  2019cites this paper
• A suspected case of drug-induced tubulointerstitial nephritis by pilocarpine hydrochloride

  2019cites this paper
• Honokiol, a Polyphenol Natural Compound, Attenuates Cisplatin-Induced Acute Cytotoxicity in Renal Epithelial Cells Through Cellular Oxidative Stress and Cytoskeleton Modulations

  2018cites this paper
• Cisplatin-Induced Rodent Model of Kidney Injury: Characteristics and Challenges

  2018influential citation
• Cisplatin nephrotoxicity: a review of the literature

  2018cites this paper
• Analysis of the Oxidative Stress Parameters in Testicular, Hepatic and Renal Tissues Homogenates of Albino Rats after Administration of Imatinib at Peripuberty

  2018cites this paper
• Self-Assembly of a [1 + 1] Ionic Hexagonal Macrocycle and Its Antiproliferative Activity

  2018cites this paper
• A critical review of adverse effects to the kidney: mechanisms, data sources, and in silico tools to assist prediction

  2018cites this paper
• Effect of rutin on cisplatin-induced damage in human mesangial cells via apoptotic pathway

  2018cites this paper
• Toxicities Associated with Cisplatin-Based Chemotherapy and Radiotherapy in Long-Term Testicular Cancer Survivors

  2018cites this paper
• EFFICIENCY OF FISH OIL IN PROTECTION OF PERIODONTAL LIGAMENT AND MANDIBULAR BONE OF RATS TREATED WITH CISPLATIN AND GAMMA RADIATION

  2017cites this paper
• Sinapic acid modulates Nrf2/HO-1 signaling pathway in cisplatin-induced nephrotoxicity in rats.

  2017influential citation
• Magnesium attenuates cisplatin-induced nephrotoxicity by regulating the expression of renal transporters.

  2017cites this paper
• EFFECT OF CHRONOMODULATED ARTESUNATE ON RENAL AND HAEMATOLOGICAL TOXICITY IN CISPLATIN-TREATED WISTAR RATS

  2017cites this paper
• On the toxicity and transport mechanisms of cisplatin in kidney tissues in comparison to a gold-based cytotoxic agent.

  2017cites this paper
• Anticancer Gold N‐Heterocyclic Carbene Complexes: A Comparative in vitro and ex vivo Study

  2017cites this paper
• Transplanted Adipose Derived Mesenchymal Stem Cells Attenuate The Acute Renal Injury Induced by Cisplatin in Rats

  2017cites this paper
• Premedication with intravenous magnesium has a protective effect against cisplatin-induced nephrotoxicity

  2017cites this paper
• The Protective Effect of Naringenin-Oxime on Cisplatin-Induced Toxicity in Rats

  2017cites this paper
• Characterization of Cardiovascular Alterations Induced by Different Chronic Cisplatin Treatments

  2017cites this paper
• Coordination-Driven Self-Assembly of Ionic Irregular Hexagonal Metallamacrocycles via an Organometallic Clip and Their Cytotoxicity Potency.

  2017cites this paper
• Nephrotoxicity of Herbal Products

  2017cites this paper
• Protective effects of apigenin and myricetin against cisplatin-induced nephrotoxicity in mice

  2017cites this paper
• Electrolyte disorders associated with the use of anticancer drugs.

  2016cites this paper
• Amniotic Fluid-Derived Mesenchymal Stem Cells Cut Short the Acuteness of Cisplatin-Induced Nephrotoxicity in Sprague-Dawley Rats

  2016cites this paper
• Population Pharmacokinetic-Toxicodynamic Modeling and Simulation of Cisplatin-Induced Acute Renal Injury in Rats: Effect of Dosing Rate on Nephrotoxicity.

  2016cites this paper
• Mechanisms of soft-tissue mineralization induced by the inhibition of the MEK/ERK pathway or the inhibition of fibroblast growth factor receptors

  2016cites this paper
• Evaluation of New Palladium Cages as Potential Delivery Systems for the Anticancer Drug Cisplatin.

  2016cites this paper
• Nicotine-Induced Apoptosis in Human Renal Proximal Tubular Epithelial Cells

  2016cites this paper
• Renal fibrosis in precision-cut kidney slices.

  2016cites this paper
• Chemopreventive Effect of Tadalafil in Cisplatin-Induced Nephrotoxicity in Rats.

  2016cites this paper
• Investigative safety strategies to improve success in drug development

  2016cites this paper
• An integrative view of cisplatin-induced renal and cardiac toxicities: Molecular mechanisms, current treatment challenges and potential protective measures.

  2016cites this paper
• Adjusting the DNA Interaction and Anticancer Activity of Pt(II) N-Heterocyclic Carbene Complexes by Steric Shielding of the Trans Leaving Group.

  2015cites this paper
• Gold(I) NHC-based homo- and heterobimetallic complexes: synthesis, characterization and evaluation as potential anticancer agents

  2015cites this paper
• Improved synthesis of N-benzylaminoferrocene-based prodrugs and evaluation of their toxicity and antileukemic activity.

  2015cites this paper
• Cisplatin-mediated cytotoxicity through inducing CYP4A 11 expression in human renal tubular epithelial cells.

  2015cites this paper
• Correlation between the Stereochemistry and Bioactivity in Octahedral Rhodium Prolinato Complexes.

  2015cites this paper
• Renal Safety Pharmacology in Drug Discovery and Development.

  2015cites this paper
• Long-term Morbidity of Testicular Cancer Treatment.

  2015cites this paper
• The Journal of Toxicological Sciences

  2015cites this paper
• Renal and Cardiovascular Damage Induced by Cisplatin in Rats

  2014cites this paper
• Novel Liver and Kidney Biomarkers for Improved Drug Safety Testing In-vitro ( 2 D and 3 D cell culture ) , pre-clinical ( animal ) and human studies

  2014cites this paper
• Protective effect of polydatin, a natural precursor of resveratrol, against cisplatin-induced toxicity in rats.

  2014cites this paper
• Caffeine-based gold(I) N-heterocyclic carbenes as possible anticancer agents: synthesis and biological properties.

  2014cites this paper
• Diclofenac toxicity in human intestine ex vivo is not related to the formation of intestinal metabolites

  2014influential citation
• An Overview of Toxicogenomics Approaches to Mechanistically Understand and Predict Kidney Toxicity

  2014cites this paper
• Development of an in vitro rat proximal tubule cell model as a platform for drug transporter and drug-drug interaction studies

  2014cites this paper
• Role of losartan on the renal cortex damage induced by cisplatin in adult male albino rats

  2014cites this paper
• Biodegradable polymeric system for cisplatin delivery: development, in vitro characterization and investigation of toxicity profile.

  2014cites this paper
• Pharmacokinetics of guanidinosuccinic acid in rat blood and cerebrospinal fluid.

  2014cites this paper
• Preparation and culture of precision-cut organ slices from human and animal

  2013influential citation
• Signalling mechanisms involved in renal pathological changes during cisplatin-induced nephropathy

  2013cites this paper