Deciphering the Oligodendrogenic Program of Neural Progenitors: Cell Intrinsic and Extrinsic Regulators

No abstract is available for this paper.

• Publication year

  2010

• Venue

  Stem Cells and Development

• Publication date

  2010-05-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1089/scd.2009.0293PMID 19938982
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Control

  2012cited by this paper
• Mesenchymal Stem Cells Prime Proliferating Adult Neural Progenitors Toward an Oligodendrocyte Fate

  2012cited by this paper
• Mesenchymal Stem Cells Enhance the Engraftment and Myelinating Ability of Allogeneic Oligodendrocyte Progenitors in Dysmyelinated Mice

  2011cited by this paper
• Notch controls embryonic Schwann cell differentiation, postnatal myelination and adult plasticity

  2009cited by this paper
• HDAC1 and HDAC2 Regulate Oligodendrocyte Differentiation By Disrupting β-Catenin-TCF Interaction

  2009cited by this paper
• Overexpression of CNTF in Mesenchymal Stem Cells reduces demyelination and induces clinical recovery in experimental autoimmune encephalomyelitis mice.

  2009cited by this paper
• Mesenchymal Stem Cells Promote Oligodendroglial Differentiation in Hippocampal Slice Cultures

  2009cited by this paper
• Sonic hedgehog promotes the generation of myelin proteins by transplanted oligosphere‐derived cells

  2009cited by this paper
• Myelin-mediated inhibition of oligodendrocyte precursor differentiation can be overcome by pharmacological modulation of Fyn-RhoA and protein kinase C signalling

  2009cited by this paper
• Vitronectin promotes oligodendrocyte differentiation during neurogenesis of human embryonic stem cells

  2009cited by this paper
• p57kip2 is dynamically regulated in experimental autoimmune encephalomyelitis and interferes with oligodendroglial maturation

  2009cited by this paper
• Interaction of NG2+ glial progenitors and microglia/macrophages from the injured spinal cord

  2009cited by this paper
• Human bone marrow‐derived mesenchymal stem cells induce Th2‐polarized immune response and promote endogenous repair in animal models of multiple sclerosis

  2009cited by this paper
• Postinjury Niches Induce Temporal Shifts in Progenitor Fates to Direct Lesion Repair after Spinal Cord Injury

  2009influential reference
• Convergent Functional Genomics of Oligodendrocyte Differentiation Identifies Multiple Autoinhibitory Signaling Circuits

  2009cited by this paper
• Promotion of central nervous system remyelination by induced differentiation of oligodendrocyte precursor cells

  2009cited by this paper
• Tenascin C and tenascin R similarly prevent the formation of myelin membranes in a RhoA‐dependent manner, but antagonistically regulate the expression of myelin basic protein via a separate pathway

  2009cited by this paper
• Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS.

  2009cited by this paper
• Paracrine control of oligodendrocyte differentiation by SRF-directed neuronal gene expression

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• Bone Marrow Stromal Cells Increase Oligodendrogenesis after Stroke

  2009cited by this paper
• LINGO-1 and its role in CNS repair.

  2008cited by this paper
• The cyclin-dependent kinase inhibitor p57kip2 is a negative regulator of Schwann cell differentiation and in vitro myelination

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• p57 kip2's role beyond Schwann cell cycle control.

  2008cited by this paper
• c-Jun is a negative regulator of myelination

  2008cited by this paper
• Negative regulation of myelination: Relevance for development, injury, and demyelinating disease

  2008cited by this paper
• Platelet-derived growth factor-AA mediates oligodendrocyte lineage differentiation through activation of extracellular signal-regulated kinase signaling pathway.

  2008influential reference
• p57kip2's role beyond Schwann cell cycle control

  2008cited by this paper
• Differentiation block of oligodendroglial progenitor cells as a cause for remyelination failure in chronic multiple sclerosis.

  2008cited by this paper
• Wnt signal transduction pathways

  2008cited by this paper
• A novel role for anosmin‐1 in the adhesion and migration of oligodendrocyte precursors

  2008cited by this paper
• Sox9 and Sox10 influence survival and migration of oligodendrocyte precursors in the spinal cord by regulating PDGF receptor α expression

  2008cited by this paper
• The balance between oligodendrocyte and astrocyte production in major white matter tracts is linearly related to serum total thyroxine.

  2008cited by this paper
• Bone morphogenetic proteins 4, 6, and 7 are up‐regulated in mouse spinal cord during experimental autoimmune encephalomyelitis

  2008cited by this paper
• Thyroid hormones promote differentiation of oligodendrocyte progenitor cells and improve remyelination after cuprizone-induced demyelination.

  2008cited by this paper
• Oligodendrogenesis of adult neural progenitors: differential effects of ciliary neurotrophic factor and mesenchymal stem cell derived factors

  2008cited by this paper
• CDK inhibitors: cell cycle regulators and beyond.

  2008cited by this paper
• Differentiation of oligodendrocytes in neurospheres derived from embryonic rat brain using growth and differentiation factors

  2007cited by this paper
• Bone Morphogenetic Protein Signaling and Olig1/2 Interact to Regulate the Differentiation and Maturation of Adult Oligodendrocyte Precursor Cells

  2007cited by this paper
• Semaphorin 3A and 3F: key players in myelin repair in multiple sclerosis?

  2007cited by this paper
• Induction of oligodendrocyte differentiation by Olig2 and Sox10: evidence for reciprocal interactions and dosage-dependent mechanisms.

  2007cited by this paper
• Sonic hedgehog promotes the migration and proliferation of optic nerve oligodendrocyte precursors.

  2007cited by this paper
• Olig1 and Sox10 Interact Synergistically to Drive Myelin Basic Protein Transcription in Oligodendrocytes

  2007cited by this paper
• Bone morphogenetic proteins promote gliosis in demyelinating spinal cord lesions

  2007cited by this paper
• LINGO-1 antagonist promotes spinal cord remyelination and axonal integrity in MOG-induced experimental autoimmune encephalomyelitis

  2007cited by this paper
• Mesenchymal stem cells: a new strategy for immunosuppression?

  2007cited by this paper
• Transforming Growth Factor-&bgr;1 Is a Negative Modulator of Adult Neurogenesis

  2006cited by this paper
• Stem cells in inflammatory demyelinating disorders: a dual role for immunosuppression and neuroprotection

  2006cited by this paper
• Mesenchymal Stem Cells Instruct Oligodendrogenic Fate Decision on Adult Neural Stem Cells

  2006cited by this paper
• PDGFRα-Positive B Cells Are Neural Stem Cells in the Adult SVZ that Form Glioma-like Growths in Response to Increased PDGF Signaling

  2006cited by this paper
• SoxD proteins influence multiple stages of oligodendrocyte development and modulate SoxE protein function.

  2006cited by this paper
• Schwann cell‐like differentiation by adult oligodendrocyte precursor cells following engraftment into the demyelinated spinal cord is BMP‐dependent

  2006cited by this paper
• Thyroid hormone deficiency changes the distribution of oligodendrocyte/myelin markers during oligodendroglial differentiation in vitro

  2006cited by this paper
• Polychlorinated biphenyls exert selective effects on cellular composition of white matter in a manner inconsistent with thyroid hormone insufficiency.

  2006cited by this paper
• Identification of Sox17 as a Transcription Factor That Regulates Oligodendrocyte Development

  2006cited by this paper
• Delayed Transplantation of Adult Neural Precursor Cells Promotes Remyelination and Functional Neurological Recovery after Spinal Cord Injury

  2006cited by this paper
• Failure of Schwann cells as supporting cells for adult neural progenitor cell grafts in the acutely injured spinal cord

  2006cited by this paper
• Olig2 Overexpression Induces the In Vitro Differentiation of Neural Stem Cells into Mature Oligodendrocytes

  2006cited by this paper
• Anosmin-1 modulates the FGF-2-dependent migration of oligodendrocyte precursors in the developing optic nerve.

  2006cited by this paper
• Myelinogenesis and Axonal Recognition by Oligodendrocytes in Brain Are Uncoupled in Olig1-Null Mice

  2005cited by this paper
• Consequences of noggin expression by neural stem, glial, and neuronal precursor cells engrafted into the injured spinal cord.

  2005cited by this paper
• Wnt signaling controls the timing of oligodendrocyte development in the spinal cord.

  2005cited by this paper
• Wnt signaling regulates the sequential onset of neurogenesis and gliogenesis via induction of BMPs

  2005cited by this paper
• LIF and BMP signaling generate separate and discrete types of GFAP-expressing cells

  2005cited by this paper
• The molecular orchestra of the migration of oligodendrocyte precursors during development.

  2005cited by this paper
• Thyroid hormone and remyelination in adult central nervous system: a lesson from an inflammatory-demyelinating disease.

  2005cited by this paper
• Analysis of congenital hypomyelinating Egr2Lo/Lo nerves identifies Sox2 as an inhibitor of Schwann cell differentiation and myelination.

  2005cited by this paper
• Roles of bHLH genes in neural stem cell differentiation.

  2005cited by this paper
• Allodynia limits the usefulness of intraspinal neural stem cell grafts; directed differentiation improves outcome

  2005cited by this paper
• Cell proliferation and replacement following contusive spinal cord injury

  2005cited by this paper
• Autologous transplantation of expanded neural precursor cells into the demyelinated monkey spinal cord.

  2004cited by this paper
• The extracellular matrix glycoprotein Tenascin‐C is expressed by oligodendrocyte precursor cells and required for the regulation of maturation rate, survival and responsiveness to platelet‐derived growth factor

  2004cited by this paper
• Thyroid hormone administration enhances remyelination in chronic demyelinating inflammatory disease

  2004cited by this paper
• bHLH Transcription Factor Olig1 Is Required to Repair Demyelinated Lesions in the CNS

  2004cited by this paper
• Olig genes are expressed in a heterogeneous population of precursor cells in the developing spinal cord

  2004cited by this paper
• Interactions between ID and OLIG proteins mediate the inhibitory effects of BMP4 on oligodendroglial differentiation

  2004cited by this paper
• Treatment of spinal cord injury by transplantation of fetal neural precursor cells engineered to express BMP inhibitor.

  2004cited by this paper
• Thyroid hormone administration enhances remyelination in chronic demyelinating inflammatory disease.

  2004cited by this paper
• Regulation of notch signaling activity.

  2004cited by this paper
• Adult neural progenitor cells provide a permissive guiding substrate for corticospinal axon growth following spinal cord injury

  2004cited by this paper
• Regulation of innate and adaptive immune responses by MAP kinase phosphatase 5

  2004cited by this paper
• Remyelination of spinal cord axons by olfactory ensheathing cells and Schwann cells derived from a transgenic rat expressing alkaline phosphatase marker gene.

  2004cited by this paper
• Platelet-derived growth factor regulates oligodendrocyte progenitor numbers in adult CNS and their response following CNS demyelination.

  2004cited by this paper
• Glial progenitors in the CNS and possible lineage relationships among them.

  2004cited by this paper
• Converse control of oligodendrocyte and astrocyte lineage development by Sonic hedgehog in the chick spinal cord.

  2004cited by this paper
• The remyelinating potential and in vitro differentiation of MOG‐expressing oligodendrocyte precursors isolated from the adult rat CNS

  2004cited by this paper
• Expression of insulin-like growth factor 1 and receptor in ischemic rats treated with human marrow stromal cells

  2004cited by this paper
• Fetal and adult human oligodendrocyte progenitor cell isolates myelinate the congenitally dysmyelinated brain

  2004cited by this paper
• The Sox9 transcription factor determines glial fate choice in the developing spinal cord.

  2003cited by this paper
• Olfactory ensheathing cells induce less host astrocyte response and chondroitin sulphate proteoglycan expression than Schwann cells following transplantation into adult CNS white matter.

  2003cited by this paper
• Temporal progressive antigen expression in radial glia after contusive spinal cord injury in adult rats

  2003cited by this paper
• Hes1 but not Hes5 regulates an astrocyte versus oligodendrocyte fate choice in glial restricted precursors

  2003cited by this paper
• Adult neural progenitor cell grafts survive after acute spinal cord injury and integrate along axonal pathways

  2003cited by this paper
• Basic helix-loop-helix factors in cortical development.

  2003cited by this paper
• NG2-expressing glial progenitor cells: an abundant and widespread population of cycling cells in the adult rat CNS.

  2003cited by this paper
• Transgenic overexpression of BMP4 increases astroglial and decreases oligodendroglial lineage commitment.

  2003cited by this paper
• Gli2 is required for normal Shh signaling and oligodendrocyte development in the spinal cord.

  2003cited by this paper
• The bHLH transcription factors OLIG2 and OLIG1 couple neuronal and glial subtype specification.

  2002cited by this paper
• Thyroid hormone activates oligodendrocyte precursors and increases a myelin-forming protein and NGF content in the spinal cord during experimental allergic encephalomyelitis

  2002cited by this paper
• Progenitor cells derived from the adult human subcortical white matter disperse and differentiate as oligodendrocytes within demyelinated lesions of the rat brain

  2002cited by this paper
• Mesenchymal Stem Cells

  2002cited by this paper

• Platelets During Myelin Repair in Multiple Sclerosis: Friend or Foe?

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• Newly Identified Deficiencies in the Multiple Sclerosis Central Nervous System and Their Impact on the Remyelination Failure

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• Targeting Fibronectin to Overcome Remyelination Failure in Multiple Sclerosis: The Need for Brain- and Lesion-Targeted Drug Delivery

  2022cites this paper
• Pericytes Favor Oligodendrocyte Fate Choice in Adult Neural Stem Cells

  2019cites this paper
• The Molecular Basis for Remyelination Failure in Multiple Sclerosis

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• Pericytes in Multiple Sclerosis.

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• Myelin plasticity, neural activity, and traumatic neural injury

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• The Thrombin Receptor Restricts Subventricular Zone Neural Stem Cell Expansion and Differentiation

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• Heterogeneous populations of neural stem cells contribute to myelin repair

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• From zebrafish to human: A comparative approach to elucidate the role of the thyroid hormone transporter MCT8 during brain development.

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• Taking Advantage of Nature’s Gift: Can Endogenous Neural Stem Cells Improve Myelin Regeneration?

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• Pushing Forward: Remyelination as the New Frontier in CNS Diseases.

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• Modulation of Oligodendrocyte Differentiation by Mechanotransduction

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• Beyond Clotting: A Role of Platelets in CNS Repair?

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• Modulation of oligodendrocyte differentiation and maturation by combined biochemical and mechanical cues

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• Intracellular Protein Shuttling: A Mechanism Relevant for Myelin Repair in Multiple Sclerosis?

  2015cites this paper
• Catalpol induces oligodendrocyte precursor cell-mediated remyelination in vitro.

  2015cites this paper
• An Examination of the Mechanisms by which Neural Precursors Augment Recovery following Spinal Cord Injury: A Key Role for Remyelination

  2014cites this paper
• The Effect of Functional Electrical Stimulation on Oligodendrocyte Biology after Spinal Cord Injury

  2014influential citation
• Fate modulation of oligodendroglial progenitor cells and adult neural stem cells

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• Characterization and functionalization of hydrogels for cell culture

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• Bone morphogenetic proteins prevent bone marrow stromal cell-mediated oligodendroglial differentiation of transplanted adult neural progenitor cells in the injured spinal cord.

  2013cites this paper
• Differentiation of neonatal dorsal root ganglion-derived neural stem cells into oligodendrocytes after intrathecal transplantation into a cauda equina lesion model.

  2013cites this paper
• Mesenchymal stromal-cell transplants induce oligodendrocyte progenitor migration and remyelination in a chronic demyelination model

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• Neuropoietic cytokines in normal brain development and neurodevelopmental disorders.

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• The Long and the Short of it: Gene and Environment Interactions During Early Cortical Development and Consequences for Long-Term Neurological Disease

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• The remyelination Philosopher's Stone: stem and progenitor cell therapies for multiple sclerosis

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• Adult mesenchymal stem cell therapy for myelin repair in multiple sclerosis.

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• A Role for the Cannabinoid 1 Receptor in Neuronal Differentiation of Adult Spinal Cord Progenitors in vitro is Revealed through Pharmacological Inhibition and Genetic Deletion

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• Mesenchymal Stem Cells Prime Proliferating Adult Neural Progenitors Toward an Oligodendrocyte Fate

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• p57kip2 regulates glial fate decision in adult neural stem cells

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• From Hydra Regeneration to Human Brain Structural Plasticity: A Long Trip through Narrowing Roads

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• Remyelination in Multiple Sclerosis: The Therapeutic Potential Of Neural And Mesenchymal Stem/Progenitor Cells

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• Mesenchymal Stem Cells Enhance the Engraftment and Myelinating Ability of Allogeneic Oligodendrocyte Progenitors in Dysmyelinated Mice

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• p57 and Cancer: Time for a Critical Appraisal

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