Water channel proteins (later called aquaporins) and relatives: Past, present, and future

No abstract is available for this paper.

• Publication year

  2009

• Venue

  IUBMB Life - A Journal of the International Union of Biochemistry and Molecular Biology

• Publication date

  2009-02-01

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1002/iub.156PMID 19165894
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Mechanism of selectivity in aquaporins and aquaglyceroporins

  2008cited by this paper
• Presence of aquaporin and V‐ATPase on the contractile vacuole of Amoeba proteus

  2008cited by this paper
• High-resolution x-ray structure of human aquaporin 5

  2008influential reference
• Junction-forming aquaporins.

  2008cited by this paper
• Aquaporins and cell migration

  2008cited by this paper
• Intracellular aquaporins: clues for intracellular water transport?

  2008cited by this paper
• Carbon Dioxide Transport through Membranes*

  2008cited by this paper
• Water movements in the brain: role of aquaporins.

  2008influential reference
• Plant aquaporins: membrane channels with multiple integrated functions.

  2008influential reference
• ER membrane aquaporins in plants

  2008influential reference
• A case of aquaporin 2 R85X mutation in a boy with congenital nephrogenic diabetes insipidus

  2008cited by this paper
• A current view of the mammalian aquaglyceroporins.

  2008influential reference
• All‐trans retinoic acid attenuates ultraviolet radiation‐induced down‐regulation of aquaporin‐3 and water permeability in human keratinocytes

  2008cited by this paper
• Aquaporin structure-function relationships: water flow through plant living cells.

  2008cited by this paper
• Barley plasma membrane intrinsic proteins (PIP Aquaporins) as water and CO2 transporters

  2008cited by this paper
• Aquaporin 7 Is a β-Cell Protein and Regulator of Intraislet Glycerol Content and Glycerol Kinase Activity, β-Cell Mass, and Insulin Production and Secretion

  2007cited by this paper
• Molecular characterization of water-selective AQP (EbAQP4) in hagfish: insight into ancestral origin of AQP4.

  2007cited by this paper
• Comparative functional analysis of aquaporins/glyceroporins in mammals and anurans

  2007cited by this paper
• Aquaporins with selectivity for unconventional permeants

  2007cited by this paper
• Functional analysis of the aquaporin gene family in Caenorhabditis elegans.

  2007cited by this paper
• Amphibian aquaporins and adaptation to terrestrial environments: a review.

  2007cited by this paper
• Plant aquaporins: Novel functions and regulation properties

  2007influential reference
• Exploring gas permeability of cellular membranes and membrane channels with molecular dynamics.

  2007cited by this paper
• The role of aquaporin 3 in teleost fish.

  2007cited by this paper
• Major intrinsic proteins (MIPs) in plants: a complex gene family with major impacts on plant phenotype

  2007influential reference
• Mouse models for congenital nephrogenic diabetes insipidus: what can we learn from them?

  2007cited by this paper
• Aquaporins in the brain: from aqueduct to “multi-duct”

  2007influential reference
• Role of aquaporins in lung liquid physiology.

  2007influential reference
• Prevention of Skin Tumorigenesis and Impairment of Epidermal Cell Proliferation by Targeted Aquaporin-3 Gene Disruption

  2007cited by this paper
• AQP7 is localized in capillaries of adipose tissue, cardiac and striated muscle: implications in glycerol metabolism.

  2007cited by this paper
• Aquaporin 1 May Be Involved in the Pathophysiology of Migraine: A Hypothesis

  2007cited by this paper
• Aquaporin 7 is a beta-cell protein and regulator of intraislet glycerol content and glycerol kinase activity, beta-cell mass, and insulin production and secretion.

  2007cited by this paper
• Aquaporins as targets for drug discovery.

  2007cited by this paper
• Structural basis of aquaporin inhibition by mercury.

  2007cited by this paper
• Localization of a Drosophila DRIP-like aquaporin in the Malpighian tubules of the house cricket, Acheta domesticus.

  2007cited by this paper
• Evidence against Functional Interaction between Aquaporin-4 Water Channels and Kir4.1 Potassium Channels in Retinal Müller Cells*

  2007influential reference
• Aquaporin superfamily with unusual npa boxes: S-aquaporins (superfamily, sip-like and subcellular-aquaporins).

  2006influential reference
• A silicon transporter in rice

  2006cited by this paper
• The Arabidopsis Major Intrinsic Protein NIP5;1 Is Essential for Efficient Boron Uptake and Plant Development under Boron Limitation

  2006cited by this paper
• Functional aquaporin diversity in plants.

  2006influential reference
• The barrier for proton transport in aquaporins as a challenge for electrostatic models: The role of protein relaxation in mutational calculations

  2006cited by this paper
• The Genome of Black Cottonwood, Populus trichocarpa (Torr. & Gray)

  2006cited by this paper
• Who discovered the water channels (aquaporins)?

  2006cited by this paper
• Crystal Structure of AqpZ Tetramer Reveals Two Distinct Arg-189 Conformations Associated with Water Permeation through the Narrowest Constriction of the Water-conducting Channel*

  2006influential reference
• Differential expression of aquaporin 7 in adipose tissue of lean and obese high fat consumers.

  2006cited by this paper
• A regrettable mistake in the award of the 2003 Nobel Prize in Chemistry: the omission of Gheorghe Benga, the first discoverer of the water channel protein in the red blood cell membrane.

  2006cited by this paper
• The structure of aquaporins

  2006influential reference
• The Role of the Tight Junction in Paracellular Fluid Transport across Corneal Endothelium. Electro-osmosis as a Driving Force

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• AQPs and Control of Vesicle Volume in Secretory Cells

  2006cited by this paper
• Point mutations in the aromatic/arginine region in aquaporin 1 allow passage of urea, glycerol, ammonia, and protons.

  2006cited by this paper
• Pathogenesis and treatment of autosomal-dominant nephrogenic diabetes insipidus caused by an aquaporin 2 mutation

  2006cited by this paper
• The structure, function and regulation of the nodulin 26-like intrinsic protein family of plant aquaglyceroporins.

  2006cited by this paper
• Identification and localization of aquaporin 5 in the mammalian conjunctival epithelium.

  2006cited by this paper
• Comments on the Discovery of water Channels, Selected for the 2003 Nobel Prize in Chemistry, and the Regrettable Omission of Gheorghe Benga

  2006cited by this paper
• Aquaporin-1 Transports NO Across Cell Membranes

  2006cited by this paper
• Water Channels (Aquaporins and Relatives): Twenty Years after Their Discovery in Cluj-Napoca, Romania

  2006cited by this paper
• Water channel proteins of adipocytes

  2006cited by this paper
• Increased migration and metastatic potential of tumor cells expressing aquaporin water channels

  2006influential reference
• Aquaporin Water and Solute Channels from Malaria Parasites and Other Pathogenic Protozoa

  2006cited by this paper
• Implications of the aquaporin-4 structure on array formation and cell adhesion.

  2006cited by this paper
• Water channel proteins: from their discovery in 1985 in Cluj-Napoca, Romania, to the 2003 Nobel Prize in Chemistry.

  2006cited by this paper
• Priorities in the discovery of the implications of water channels in epilepsy and Duchenne muscular dystrophy.

  2006cited by this paper
• Why do microorganisms have aquaporins?

  2006influential reference
• Structural mechanism of plant aquaporin gating

  2006influential reference
• The discovery by Gh. Benga of the first water channel protein in 1985 in Cluj-Napoca, Romania, A few years before P. Agre (2003 Nobel Prize in Chemistry).

  2006cited by this paper
• Aquaporin gating.

  2006cited by this paper
• The Role of Aquaporin Water Channels in Fluid Secretion by the Exocrine Pancreas

  2006cited by this paper
• Proteomic knowledge of human aquaporins

  2006cited by this paper
• Comment on: cloning and characterization of porcine aquaporin 1 water channel expressed extensively in the gastrointestinal system.

  2006cited by this paper
• The story of the discovery of aquaporins: convergent evolution of ideas--but who got there first?

  2006cited by this paper
• Water channel proteins: from their discovery in Cluj-Napoca, Romania in 1985, to the 2003 Nobel Prize in chemistry and their implications in molecular medicine.

  2006cited by this paper
• Evidence that aquaporin 1 is a major pathway for CO2 transport across the human erythrocyte membrane

  2006cited by this paper
• Cloning and characterization of porcine aquaporin 1 water channel expressed extensively in gastrointestinal system.

  2006cited by this paper
• Accelerated cataract formation and reduced lens epithelial water permeability in aquaporin-1-deficient mice.

  2006cited by this paper
• Priorities in the discovery of the implications of water channels in epilepsy and duchenne muscular dystrophy.

  2006cited by this paper
• Aquaporins in Saccharomyces cerevisiae wine yeast.

  2006cited by this paper
• The renal plumbing system: aquaporin water channels

  2005cited by this paper
• A Novel Plant Major Intrinsic Protein in Physcomitrella patens Most Similar to Bacterial Glycerol Channels1

  2005cited by this paper
• Developmental expression and biophysical characterization of a Drosophila melanogaster aquaporin.

  2005cited by this paper
• IgG marker of optic-spinal multiple sclerosis binds to the aquaporin-4 water channel

  2005cited by this paper
• What makes an aquaporin a glycerol channel? A comparative study of AqpZ and GlpF.

  2005cited by this paper
• The Journal of Experimental Medicine CORRESPONDENCE

  2005cited by this paper
• Novel type aquaporin SIPs are mainly localized to the ER membrane and show cell‐specific expression in Arabidopsis thaliana

  2005cited by this paper
• Modeling association in longitudinal binary outcomes: A brief review

  2005cited by this paper
• Aquaporin‐3 functions as a glycerol transporter in mammalian skin

  2005influential reference
• Regulation of expression of two aquaporin homologs in the intestine of the European eel: effects of seawater acclimation and cortisol treatment.

  2005cited by this paper
• Disruption of Aquaporin-11 Produces Polycystic Kidneys following Vacuolization of the Proximal Tubule

  2005cited by this paper
• Defective water and glycerol transport in the proximal tubules of AQP7 knockout mice.

  2005cited by this paper
• Structural basis for conductance by the archaeal aquaporin AqpM at 1.68 A.

  2005influential reference
• Phylogeny and evolution of the major intrinsic protein family

  2005cited by this paper
• Marine Fish Egg Hydration Is Aquaporin-Mediated

  2005cited by this paper
• Aquaporins from pathogenic protozoan parasites: structure, function and potential for chemotherapy

  2005cited by this paper
• Aquaporins as targets for drug discovery.

  2005cited by this paper
• Aquaporins in yeasts and filamentous fungi

  2005influential reference
• Loss of perivascular aquaporin 4 may underlie deficient water and K+ homeostasis in the human epileptogenic hippocampus.

  2005cited by this paper
• Why does the mammalian red blood cell have aquaporins?

  2005cited by this paper
• Regulation of plant aquaporin activity

  2005cited by this paper
• MIPDB: a relational database dedicated to MIP family proteins

  2005cited by this paper
• Discovery of the Porosome: revealing the molecular mechanism of secretion and membrane fusion in cells

  2004cited by this paper
• The Saccharomyces cerevisiae aquaporin Aqy1 is involved in sporulation.

  2004cited by this paper

• Genome-wide identification of aquaporin and their potential role in osmotic pressure regulation in Ruditapes philippinarum.

  2025cites this paper
• Aquaporin Gene Expression in Cultured Buffalo Cumulus and Fibroblast Cells

  2025cites this paper
• Da-Yuan-Yin decoction suppresses NETs formation, inhibits the IL-23/JAK2/STAT3 signalling pathway, and modulates metabolic profiles and gut microbiota composition in damp-heat syndrome

  2025cites this paper
• Serum Aquaporin-1 and 3 Levels in Term Newborns

  2025cites this paper
• A Comparative Analysis of Erythrocyte Osmotic Fragility across Vertebrate Taxa

  2024cites this paper
• Application of Aquaporins as Markers in Forensic Pathology: A Systematic Review of the Literature

  2024cites this paper
• A composite vase solution improved vase quality of cut peony after long-term cold storage by maintaining better physiological activities and enhancing the absorption of water

  2024cites this paper
• Comparative Analysis of the Osmotic Fragility of Erythrocytes Across Various Taxa of Vertebrates

  2024cites this paper
• Roles and regulation of Aquaporin-3 in maintaining the gut health: an updated review

  2023cites this paper
• AQP1 in the Gastrointestinal Tract of Mice: Expression Pattern and Impact of AQP1 Knockout on Colonic Function

  2023cites this paper
• Ontogenetic development of the water channel protein AQP5 in mouse salivary gland tissue

  2023cites this paper
• Light and Scanning Electron Microscopy of Red Blood Cells From Humans and Animal Species Providing Insights into Molecular Cell Biology

  2022cites this paper
• EuPIP1;2, a Plasma Membrane Aquaporin Gene from Eucommia ulmoides, Enhances Drought and Salt Tolerance in Transgenic Tobacco

  2022cites this paper
• Vaccines as a Strategy to Control Trichinellosis

  2022cites this paper
• Inflammatory bowel disease: an overview of Chinese herbal medicine formula-based treatment

  2022cites this paper
• Aquaporins: A new target for traditional Chinese medicine in the treatment of digestive system diseases

  2022cites this paper
• Overexpression of the Eucommia ulmoides Aquaporin, EuPIP1;1, Promotes Leaf Growth, Flowering and Bolting, and Stress Tolerance in Arabidopsis

  2022cites this paper
• Phytoremediation of Arsenic Contaminated Water Using Aquatic, Semi-Aquatic and Submerged Weeds

  2021cites this paper
• Alterations in aquaporin gene expression level on cyclophosphamide-induced cardiac injury and possible protective role of Ganoderma lucidum

  2021cites this paper
• Acute or chronic pulmonary emphysema? Or both?—A contribution to the diagnosis of death due to violent asphyxiation in cases with pre-existing chronic emphysema

  2021cites this paper
• Overexpression of the Zygophyllum xanthoxylum Aquaporin, ZxPIP1;3, Promotes Plant Growth and Stress Tolerance

  2021cites this paper
• Silencing of Aquaporin Homologue Accumulates Uric Acid and Decreases the Lifespan of the Asian Citrus Psyllid, Diaphorina citri (Hemiptera: Liviidae)

  2021cites this paper
• The role of AQP3 and AQP4 channels in cisplatin-induced cardiovascular edema and the protective effect of melatonin

  2021cites this paper
• The role of aquaporins in the regulation of body fluids homeostasis

  2020cites this paper
• TRANSMEMBRANE ION AND WATER TRANSPORTS IN ERYTHROCYTE VOLUME HOMEOSTASIS: AN OVERVIEW OF THE PHYSIOLOGIC PROCESSES

  2020cites this paper
• Role of Aquaporins in the Physiological Functions of Mesenchymal Stem Cells

  2020cites this paper
• Pharmacogenomics with red cells: a model to study protein variants of drug transporter genes

  2020cites this paper
• Evaluation of Aquaporins 1 and 5 Expression in Rat Parotid Glands After Volumetric Modulated Arc Radiotherapy and Use of Low-Level Laser Therapy at Different Times.

  2020cites this paper
• Up-concentration of succinic acid, lactic acid, and ethanol fermentations broths by forward osmosis

  2020cites this paper
• Molecular Cloning of cDNA Encoding an Aquaglyceroporin , AQP-h 9 , in the Japanese Tree Frog , Hyla japonica : Possible Roles of AQP-h 9 in Freeze Tolerance

  2019cites this paper
• Liver Fibrosis Conventional and Molecular Imaging Diagnosis Update

  2019cites this paper
• Plant Aquaporins: Diversity, Evolution and Biotechnological Applications.

  2019cites this paper
• Production and recovery of valuable bioproducts through anerobic fermentation of organic waste.

  2019cites this paper
• Biomimetic and bioinspired membranes for water purification: A critical review and future directions

  2019cites this paper
• Osmotic tolerance of avian erythrocytes to complete hemolysis in solute free water

  2019cites this paper
• Urea and ammonium rejection by an aquaporin-based hollow fiber membrane

  2019cites this paper
• Ion channels and transporters in adipose-derived stem cells

  2018cites this paper
• Artificial water channels—deconvolution of natural Aquaporins through synthetic design

  2018cites this paper
• Mechanism of Treatment Methods of Arsenic-Contaminated Water

  2018cites this paper
• Vaccines against Trichinella spiralis: Progress, challenges and future prospects

  2018cites this paper
• Aquaporin1 and 3 modification as a result of chondrogenic differentiation of human mesenchymal stem cell

  2018cites this paper
• Identification and Functional Analysis of the First Aquaporin from Striped Stem Borer, Chilo suppressalis

  2018cites this paper
• Rejection of trace organic water contaminants by an Aquaporin-based biomimetic hollow fiber membrane

  2018cites this paper
• SYNTHESIS OF BIOLOGICALLY-INSPIRED NANOFILTRATION MEMBRANES USING PROTECTED, MUTATED, AND SIMULATED AQUAPORINS

  2018influential citation
• Molecular mechanism of the increased tissue uptake of trivalent inorganic arsenic in mice with type 1 diabetes mellitus.

  2018cites this paper
• Selection of housekeeping genes and demonstration of RNAi in cotton leafhopper, Amrasca biguttula biguttula (Ishida)

  2018cites this paper
• Knock down of Whitefly Gut Gene Expression and Mortality by Orally Delivered Gut Gene-Specific dsRNAs

  2017cites this paper
• AQP-4 AND ITS ROLE IN MAINTAINING THE HYDRIC BALANCE IN THE BRAIN

  2017cites this paper
• Aquaporins in the male reproductive tract and sperm: Functional implications and cryobiology

  2017cites this paper
• Are Aquaporins (AQPs) the Gateway that Conduits Nutrients, Persistent Organic Pollutants and Perfluoroalkyl Substances (PFASs) into Plants?

  2017cites this paper
• Aquaporins in boar and bull spermatozoa: identification and functional implications

  2017cites this paper
• Functional and molecular analysis of Organic Cation Transporters (OCTs and OCTNs) in human airway epithelial cells and macrophages

  2017cites this paper
• Heparin-Binding Epidermal Growth Factor–Like Growth Factor Enhances Aquaporin 3 Expression and Function During Mouse Embryo Implantation

  2017cites this paper
• Aquaglyceroporins in the kidney: present state of knowledge and prospects.

  2016cites this paper
• AcEBP1, an ErbB3-Binding Protein (EBP1) from halophyte Atriplex canescens, negatively regulates cell growth and stress responses in Arabidopsis.

  2016cites this paper
• Putative new groups of invertebrate water channels based on the snail Helix pomatia L. (Helicidae) MIP protein identification and phylogenetic analysis.

  2016cites this paper
• Molecular and functional characterization of Bemisia tabaci aquaporins reveals the water channel diversity of hemipteran insects.

  2016cites this paper
• Molecular Pathology of Pulmonary Edema in Forensic Autopsy Cases with Special Regard to Fatal Methamphetamine Intoxication

  2016cites this paper
• Root Pressure: Getting to the Root of Pressure

  2016cites this paper
• Quantitative assessment of early liver fibrosis in rats using 13N-NH3·H2O PET/CT

  2015cites this paper
• Immunohistochemical identification of aquaporin 2 in the kidneys of wild boars (Sus scrofa)

  2015influential citation
• Morphology and water permeability of red blood cells from green sea turtle (Chelonia mydas)

  2015cites this paper
• Hyperosmotic stress induces cisplatin sensitivity in ovarian cancer cells by stimulating aquaporin-5 expression

  2015cites this paper
• AcPIP2, a plasma membrane intrinsic protein from halophyte Atriplex canescens, enhances plant growth rate and abiotic stress tolerance when overexpressed in Arabidopsis thaliana

  2015cites this paper
• Cloning, identification, and bioinformatics analysis of a putative aquaporin TsAQP from Trichinella spiralis.

  2015cites this paper
• Aquaporins in the female reproductive system of mammals.

  2015cites this paper
• Molecular Cloning of cDNA Encoding an Aquaglyceroporin, AQP-h9, in the Japanese Tree Frog, Hyla japonica: Possible Roles of AQP-h9 in Freeze Tolerance

  2015cites this paper
• Oxidation Status of β-Thalassemia Minor and Hb H Disease, and Its Association with Glycerol Lysis Time (GLT50)

  2014influential citation
• Novel vasotocin-regulated aquaporins expressed in the ventral skin of semiaquatic anuran amphibians: evolution of cutaneous water-absorbing mechanisms.

  2014cites this paper
• Molecular and functional characterization of multiple aquaporin water channel proteins from the western tarnished plant bug, Lygus hesperus.

  2014cites this paper
• Electric polarization properties of single bacteria measured with electrostatic force microscopy.

  2014cites this paper
• Ion/water channels for embryo implantation barrier.

  2014cites this paper
• AQP1 expression in human gingiva and its correlation with periodontal and peri-implant tissue alterations.

  2014cites this paper
• Immunohistochemical identification of aquaporin 2 in the kidneys of young beef cattle

  2014influential citation
• Water permeability of the mammalian cochlea: functional features of an aquaporin-facilitated water shunt at the perilymph–endolymph barrier

  2014cites this paper
• Gene expression and localization of two types of AQP5 in Xenopus tropicalis under hydration and dehydration.

  2014cites this paper
• The Role of Aquaporin 3 (AQP3) in Breast Cancer

  2014influential citation
• Transfer of tritium released into the marine environment by French nuclear facilities bordering the English Channel.

  2013cites this paper
• The Gating Mechanism of the Human Aquaporin 5 Revealed by Molecular Dynamics Simulations

  2013cites this paper
• Phospholipid Membrane Protection by Sugar Molecules during Dehydration—Insights into Molecular Mechanisms Using Scattering Techniques

  2013cites this paper
• In vivo analysis of aquaporin 0 function in zebrafish: permeability regulation is required for lens transparency.

  2013cites this paper
• Regulation and transport mechanisms of eukaryotic aquaporins

  2013cites this paper
• Trypanosoma brucei aquaglyceroporin 2 is a high-affinity transporter for pentamidine and melaminophenyl arsenic drugs and the main genetic determinant of resistance to these drugs

  2013cites this paper
• The expression and distribution of aquaporin 3 in mouse embryos before and after vitrification

  2013cites this paper
• Molecular pathology of pulmonary edema in forensic autopsy cases with special regard to fatal hyperthermia and hypothermia.

  2013cites this paper
• The key role of aquaporin 3 and aquaporin 10 in the pathogenesis of pompholyx.

  2013cites this paper
• Does Aquaporin-1 expression have clinical significance in serous epithelial ovarian cancer?

  2013cites this paper
• Water Homeostasis and Osmoregulation as Targets in the Control of Insect Pests

  2013cites this paper
• Roles of Aquaporins in Osmoregulation, Desiccation and Cold Hardiness in Insects

  2013cites this paper
• AQUAPORINOLOGY (THE STUDY OF WATER CHANNEL PROTEINS - AQUAPORINS AND RELATIVES) AS A NEW DOMAIN OF NATURAL SCIENCES

  2013cites this paper
• SOLVENT EFFECT ON AQUAPORIN4

  2013cites this paper
• Implications of water channel proteins in selected neurological disorders: epilepsies, muscular dystrophies, amyotrophic lateral sclerosis, neuromyelitis optica, Parkinson's disease, and spongiform encephalopathies.

  2012influential citation
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  2012cites this paper
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  2012cites this paper
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  2012cites this paper
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  2012cites this paper
• The Activity of Human Aquaporin 1 as a cGMP-Gated Cation Channel Is Regulated by Tyrosine Phosphorylation in the Carboxyl-Terminal Domain

  2012cites this paper
• Water channel proteins in the gastrointestinal tract.

  2012cites this paper
• On the definition, nomenclature and classification of water channel proteins (aquaporins and relatives).

  2012cites this paper