ATP-sensitive potassium channel modulators and cardiac arrhythmias: an update.

No abstract is available for this paper.

• Publication year

  2014

• Venue

  Current pharmaceutical design

• Publication date

  2014-12-30

• Fields of study

  Medicine

• Identifiers
  DOI 10.2174/1381612820666141029102800PMID 25354183
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• The cardiac sarcolemmal ATP-sensitive potassium channel as a novel target for anti-arrhythmic therapy.

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• Genetic disruption of Kir6.2, the pore-forming subunit of ATP-sensitive K+ channel, predisposes to catecholamine-induced ventricular dysrhythmia.

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• Gene targeting approach to clarification of ion channel function: studies of Kir6.x null mice

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• Effects of a Novel Cardioselective ATP-Sensitive Potassium Channel Antagonist, 1-[[5-[2-(5-Chloro-o-anisamido)ethyl]-β-methoxyethoxyphenyl]sulfonyl]-3-methylthiourea, Sodium Salt (HMR 1402), on Susceptibility to Ventricular Fibrillation Induced by Myocardial Ischemia: In Vitro and in Vivo Studies

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